الصفحة 43
الصفحة 43
Oxidative Stress and Neuroprotection
This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.
Oxidative Phosphorylation in Health and Disease
Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, function, and molecular biology of the mitochondrial respiratory chain, information on traditional diagnostical methodologies, and an overview of the diagnostic promise of new technologies. The hypermetabolism of Luft disease, although only seen twice, is also studied. There are critical reviews of symptoms and signs associated with syndromes, as well as updates on the genetic defects of either the mitochondrial or the nuclear genome responsible for many disorders.
Oxidation : The Cornerstone of Carcinogenesis: Oxidation and Tobacco Smoke Carcinogenesis : A Relationship Between Cause and Effect
In order to learn oncology, it is necessary to acquire a comprehensive knowledge of molecular biology in carcinogenesis, and then, with this as a background, to consider the principles of the theoretical and clinical basis of the subject. For graduate students who are preparing themselves for the specialty of internal medicine or clinical oncology, and physicians who wish to become proficient in oncology, it is exceedingly difficult to be highly skilled and completely informed in this expanding field of science without a comprehensive text on the subject. This book is unique, due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. I hope this book will prove to be a helpful companion to the internist, the oncologist and the research scientist in molecular biology as well as a work of reference for the general practitioner and physician interested in cancer research.
Oxidants in Biology : A Question of Balance
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
Oxford textbook of anaesthesia for oral and maxillofacial surgery ; 2nd ed.
Encompasses a wide range of procedures, treatments, and interventions for pathologies affecting the teeth, mouth, and jaw. To provide safe and effective care to this diverse and often challenging patient population, in a variety of clinical settings, requires an in-depth understanding of the specific challenges posed by this cohort, a comprehensive knowledge of the underlying pathologies and associated comorbidities, and an appreciation of the implications of a ‘shared airway’.
Oxford Professional Practice : Handbook of Patient Safety
Empowers doctors, nurses and other professionals to be able to develop safe clinical processes that allow proactive management and minimisation of risk, so that people are not harmed when they receive clinical care. It gives the rationale for patient safety, the theories behind the science of patient safety and then the practical methods that frontline staff can use on a daily basis to decrease harm.
Oxford Handbook of Head and Neck Anatomy
A sound knowledge of anatomy forms the scientific backbone of medicine and surgery – equipping the owner with the tools necessary to understand, remember and ultimately manage the clinical scenarios encountered throughout ones career. The Oxford Handbook of clinical head and neck anatomy is a novel venture for the Oxford Handbook series into the field of anatomy. It tackles the notoriously difficult three-dimensional anatomy of the head and neck and provides clinically relevant correlates, etymology and a brief insight into the people behind the commonly encountered eponymous structures and syndromes.
Oxford handbook of dental nursing
Enables users to find relevant information quickly, and will support dental nurses in their everyday work and provide easy access to information they may require in clinical sessions. As well as the basics it highlights the core competencies and contains further information which is of use to qualified dental nurses working in general dental practice, in the NHS or private sector, dental hospitals, and community dental services.
Oxford Handbook of Clinical Surgery
Provides an accessible pocket reference for surgical trainees, medical students, and all those involved in the care of the surgical patient. It is thoroughly comprehensive, without sacrificing the clear, concise, and quick-reference style the Oxford Medical Handbooks are known for. It provides surgically relevant anatomy and physiology, quick reference symbols, key diagrams, and a focus on evidence-based practice with key references throughout.
Oxford handbook of clinical medicine
A complete and concise guide to the core areas of medicine that also encourages thinking about the world from the patient's perspective, offering a holistic, patient-centred approach. Loved and trusted by millions for over three decades, the Oxford Handbook of Clinical Medicine continues to be a truly indispensable companion for the practice of modern medicine
Oxford Handbook of Clinical Dentistry ; 7th ed.
It balances a pragmatic approach alongside evidence-based clinical knowledge, guidelines, and protocols. It details how to take a history and perform an examination, moving on to discussing preventive and community dentistry, paediatric dentistry, and orthodontics. It thoroughly examines the subject of restorative dentistry through periodontology, tooth repair, tooth replacement, endodontics, and dental implants. It also explores oral surgery, oral medicine, and maxillofacial surgery
Oxford Clinical Guidelines : Newly Qualified Doctor
Summarises the key clinical practice guidelines which all final year medical students and Foundation Year 1 and 2 doctors should know when managing common conditions. Logically organised by medical specialty, the reader can quickly familiarise themselves with the key principles of diagnosis and management at the appropriate level for beginning a new rotation on the wards.
Oxford Assess and Progress: Clinical Dentistry
An authoritative guide for dental students providing a wealth of revision. Organised by specialties, chapter introductions unlock difficult subjects with hints and tips. Each question is accompanied by detailed answers explaining the rationale behind right and wrong answers.
Overweight and the Metabolic Syndrome : From Bench to Bedside
This volume examines the problem of the overweight individual and the metabolic syndrome from the laboratory bench to the bedside. Clearly, translating the findings we make in the laboratory to the betterment of humankind is an important mission. Areas where basic science is making important contributions to the problems associated with metabolic syndrome are illustrated in the chapters on Neuroendocrine Control of Food Intake, Current Views of the Fat Cell as an Endocrine Cell: Lipotoxicity, and Ectopic Fat and Metabolic Syndrome. For each of these, the fast-moving basic science area is opening new vistas for translation to the bedside and clinic.
Overcoming Insomnia
Nowadays, a high percentage of the population in modern society suffers from various kinds of sleep disturbances, due to the impact of increased physiological and socio-cultural stress factors. One of the most common sleep complaints, which the human being has suffered from since ancient times, is insomnia. Although its literal meaning is a total lack of sleep, in clinical and practical terms insomnia has come to refer to a difficulty in initiating and/or maintaining sleep, or non-restorative, non-refreshing sleep. In a survey conducted in the general population of different countries, the prevalence of insomnia was estimated to be about one third of the adult population.
Ovarian Cancer : State of the Art and Future Directions in Translational Research
Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. The Symposium on Ovarian Cancer: State of the Art and Future Directions intends to bring together international experts interested in the development of novel diagnostic, prognostic and therapeutic tools for ovarian cancer. The meeting will function as a think tank where clinicians, translational and basic scientists, and parties from the biotechnology and pharmaceutical industry will get together to review recent advances in clinical research and translational science in ovarian cancer and define areas of future research opportunities and priorities.
Outdoor Learning and Play : Pedagogical Practices and Children's Cultural Formation
Examines children’s participation in dialectical reciprocity with place-based institutional practices by presenting empirical research from Australia, Brazil, China, Poland, Norway and Wales. Underpinned by cultural-historical theory, the analysis reveals how outdoors and nature form unique conditions for children's play, formal and informal learning and cultural formation. The analysis also surfaces how inequalities exist in societies and communities, which often limit and constrain families' and children's access to and participation in outdoor spaces and nature. The findings highlight how institutional practices are shaped by pedagogical content, teachers' training, institutional regulations and societal perceptions of nature, children and suitable, sustainable education for young children. Due to crises, such as climate change and the recent pandemic, specific focus on the outdoors and nature in cultural formation is timely for the cultural-historical theoretical tradition. In doing so, the book provides empirical and theoretical support for policy makers, researchers, educators and families to enhance, increase and sustain outdoor and nature education.
Othodontic aligner treatment : A review of materials, clinical management, and evidence
Introduces and discusses all the presently available thermoplastically formed products that apply a predetermined strain to the teeth and jaw, with the goal of correcting malpositioned teeth, while also being esthetically acceptable for the patient.
Orthopoxviruses Pathogenic for Humans
Orthopoxviruses Pathogenic for Humans covers those viruses capable of causing disease in man, including monkeypox, smallpox, cowpox, and vaccinia. The coverage of each virus is comprehensive, covering the biology, molecular biology, and ecology of the virus as well as the clinical and epidemiological aspects of these viruses in humans and animals. In addition, this volume highlights developments in genetic engineering that are paving the way for potential therapeutic treatments of these viruses.
Orthodontics for Dental Hygienists and Dental Therapists
Covers essential orthodontic theory for dental hygienists and dental therapists Clear, comprehensive, and easy to read, Orthodontics for Dental Hygienists and Dental Therapists outlines orthodontic theory and explains clinical techniques, without assuming prior knowledge. By learning the orthodontic mechanics and fundamentals, dental hygiene and therapy students can become valuable team members in an orthodontic practice. Student-friendly guide to essential orthodontic theory and clinical techniques for dental hygienists, dental therapists, and oral health therapists. Superbly illustrated with explanations on terminologies, orthodontic appliances, instruments, and procedures / Features multiple choice questions at the end of each chapter and interactive self-assessment questions on a companion website to help you test your knowledge
