الصفحة 41
الصفحة 41
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Deciphering Growth

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.

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Decentralised Government in an Integrating World: Quantitative Studies for OECD Countries

The book offers a comprehensive empirical analysis of the determinants of changes in the distribution of expenditure and revenue-raising powers among fiscal tiers in OECD countries. Using a new indicator of fiscal decentralisation which accounts for subnational decision-making autonomy, common decentralisation trends are investigated.

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Death Threats and Violence : New Research and Clinical Perspectives

Threats of violence—and especially of homicide—are a too-familiar part of modern life, paralleling stressful conditions at home, on the job, on campus, and in relationships. Death Threats and Violence analyzes the meaning and impact of homicidal threats, the means by which they are communicated, and their development from infrequent private occurrence to ongoing social problem.

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Death in a consumer culture

Organised into five sections covering: The death industry; death rituals; death and consumption; death and the body; and alternate endings, The book explores topics from celebrity death tourism, pet and online memorialization; family history research, to alternatives to traditional corpse disposal methods and patient-assisted suicide. Work from scholars in history, religious studies, sociology, psychology, anthropology, and cultural studies sits alongside research in marketing and consumer culture.

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Daylighting Design Planning Strategies and Best Practice Solutions

The primary objective of daylight systems is to make maximum use of daylight for certain building types and climates. The book documents the various dimensions of the optimum use of daylight with particular reference to window orientation, light distribution, and prism technology, and discusses the health and economic related aspects.

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Datatype-Generic Programming ; International Spring School, SSDGP 2006, Nottingham, UK, April 24-27, 2006, Revised Lectures

A leitmotif in the evolution of programming paradigms has been the level and extent of parametrisation that is facilitated — the so-called genericity of the paradigm. The sorts of parameters that can be envisaged in a programming language range from simple values, like integers and fioating-point numbers, through structured values, types and classes, to kinds (the type of types and/or classes).Datatype-generic programming is about parametrising programsby the structure of the data that they manipulate. To appreciate the importance of data type genericity,one need look no further than the internet. The internet is a massive repository of structured data, but the structure is rarely exploited. For example, compression of data can be much more efiective if its structure is known, but most compression algorithms regard the input data as simply a string of bits, and take no account of its internal organisation. Datatype-generic programming is about exploiting the structure of data when it is relevant and ignoring it when it is not. Programming languages most c- monly used at the present time do not provide efiective mechanisms for do- menting and implementing datatype genericity.

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Database and expert systems applications ; DEXA 2020 International workshops BIOKDD, IWCFS and MLKgraphs, Bratislava, Slovakia, September 14–17, 2020, Proceedings

This volume constitutes the refereed proceedings of the three workshops held at the 31st International Conference on Database and Expert Systems Applications, DEXA 2020, held in September 2020: The 11th International Workshop on Biological Knowledge Discovery from Data, BIOKDD 2020, the 4th International Workshop on Cyber-Security and Functional Safety in Cyber-Physical Systems, IWCFS 2020, the 2nd International Workshop on Machine Learning and Knowledge Graphs, MLKgraphs2019. Due to the COVID-19 pandemic the conference and workshop were held virtually. The 10 papers were thoroughly reviewed and selected from 15 submissions, and discuss a range of topics including: knowledge discovery, biological data, cyber security, cyber-physical system, machine learning, knowledge graphs, information retriever, data base, and artificial intelligent.

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Data rights in transition

Maps the development of data rights that formed and reformed in response to the socio-technical transformations of the postwar twentieth century. The authors situate these rights, with their early pragmatic emphasis on fair information processing, as different from and less symbolically powerful than utopian human rights of older centuries

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Data parallel C++programming accelerated systems using C++ and SYCL

Full of practical advice, detailed explanations, and code examples to illustrate key topics. SYCL enables access to parallel resources in modern accelerated heterogeneous systems. Now, a single C++ application can use any combination of devices–including GPUs, CPUs, FPGAs, and ASICs–that are suitable to the problems at hand. This book teaches data-parallel programming using C++ with SYCL and walks through everything needed to program accelerated systems. The book begins by introducing data parallelism and foundational topics for effective use of SYCL. Later chapters cover advanced topics, including error handling, hardware-specific programming, communication and synchronization, and memory model considerations.

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Data parallel C++ : Mastering DPC++ for programming of heterogeneous systems using C++ and SYCL

This book teaches data-parallel programming using C++ and the SYCL standard from the Khronos Group and walks through everything needed to use SYCL for programming heterogeneous systems. The book begins by introducing data parallelism and foundational topics for effective use of SYCL and Data Parallel C++ (DPC++), the open source compiler used in this book.

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Data Mining in Bioinformatics

8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biological research has shifted from genome sequences to protein functionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erent tissues, its3Dstructure and activesites,its functionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support.

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Data Mining and Diagnosing IC Fails

This book brings together a large number of analysis techniques that are suitable for IC fail data, but that are not available elsewhere in a single place. Several of the techniques, in fact, have been presented only recently in technical conferences. The purpose of the book is to bring together in one place a large number of analysis, data mining and diagnosis techniques that have proven to be useful in analyzing IC fails. The descriptions of the techniques and analysis routines is sufficiently detailed that profession manufacturing engineers can implement them in their own work environment

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Data feminism

We have seen through many examples that data science and artificial intelligence can reinforce structural inequalities like sexism and racism. Data is power, and that power is distributed unequally. This book offers a vision for a feminist data science that can challenge power and work towards justice. This book takes a stand against a world that benefits some (including the authors, two white women) at the expense of others. It seeks to provide concrete steps for data scientists seeking to learn how feminism can help them work towards justice, and for feminists seeking to learn how their own work can carry over to the growing field of data science.

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Danno Vascolare E Tromboemostasi : Fisiopatologia e patologia clinica = Vascular injury and thrombohemostasis : Pathophysiology and clinical pathology

Quest’opera descrive alcuni meccanismi chiave dell’angiogenesi e le opportunità riguardanti lo sviluppo di nuove strategie in campo terapeutico. Il volume fornisce un quadro esaustivo della materia spaziando dall’embriologia dei vasi e del sistema emopoietico ai più avanzati approcci terapeutici, primo fra tutti quello che si basa sull'utilizzazione del sangue midollare autologo ad attività staminalica. Grande rilevanza viene inoltre attribuita alla patogenesi dei difetti dell’emostasi e della coagulazione, all’ipertensione arteriosa e ai difetti del quadro lipidico.

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Damage and Cracking of Concrete Structures : From Theory to Practice

Understanding and managing damage and cracking in concrete is essential to ensuring the integrity and durability of civil engineering structures. This book also addresses many situations, such as monotonic or cyclic behavior, seismic responses, a description of fast dynamic situations and effects due to the maturation of concrete at an early age in massive structures. Numerous detailed exercises are provided to help students to understand modeling and calculation techniques.

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Cytokines and Cancer

This volume provides a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies.The volume is divided in two sections. Section one focuses on current developments in the basic science field with particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second section deals with translational and clinical research in the field, and many of the chapter authors were among the first to introduce several cytokines in the treatment of certain tumors.

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Cytochrome P450 : Structure, Mechanism, and Biochemistry

In this newest edition, we find that the newest discussion of P450 structure includes information of bacterial (soluble) P450s interwoven with that of eukaryotic (membrane bound) of this superfamily, highlighting the newest developments in this area. The complete battery of human P450s is now known and summarized in the new edition. In addition, general overviews of plant P450s and those from microbes contained within this newest edition provide a broader view of P450 diversity than seen in earlier editions. Each of these three editions should be on bookshelves of laboratories studying P450s. The third edition of Cytochrome P450: Structure, Mechanism, and Biochemistry provides an opportunity to judge progress in many key areas of P450 research while at the same time learn of new directions in the field. It is an excellent and most useful volume.

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Cyclin Dependent Kinase 5 (Cdk5)

Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during development as well as in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role that Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may have therapeutic potential for the treatment of a number of neurodegenerative diseases.

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Cybersecurity in Poland : Legal Aspects

This book explores the legal aspects of cybersecurity in Poland. The authors are not limited to the framework created by the NCSA (National Cybersecurity System Act – this act was the first attempt to create a legal regulation of cybersecurity and, in addition, has implemented the provisions of the NIS Directive) but may discuss a number of other issues. The book presents international and EU regulations in the field of cybersecurity and issues pertinent to combating cybercrime and cyberterrorism. Moreover, regulations concerning cybercrime in a few select European countries are presented in addition to the problem of collision of state actions in ensuring cybersecurity and human rights.

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Current Topics in Innate Immunity

This volume represents a collection of topics on natural killer cells, mast cells, phagocytes, toll like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches discussed during the conference.

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