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Cancer grading manual
Cancer Grading Manual addresses all histopathologic aspects of tumor pathology essential for grading of tumors. It discusses the history and basic tenets of tumor grading; principles of microscopic grading of tumors; ancillary methods currently used to improve tumor grading; and new techniques used in evaluating tumors and formulating prognosis. It is designed to be a practice-oriented, concise and well-illustrated resource for diagnostic surgical pathologists and pathology residents.
Cancer drug resistance : methods and protocols
Discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry.
Cancer cell biology : methods and protocols
Provides detailed methods on the mechanisms of underlying cancer cell biology. Chapters guide readers through techniques for culturing cancer cell lines, xenografts, cryopreservation of tumor cells, analyzing the co-culture of breast cancer cells, protein secretion by ELISA, flow cytometry-based, multi-parametric immunofluorescence analysis, protein expression by western blot, analysis of surface protein levels, protein recycling by biotinylation assay, and proteomics analysis by liquid chromatography-mass spectrometry.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
By-catch Reduction in the Worlds Fisheries
This book comes after several decades of outstanding and successful research that has helped ameliorate some of the most important and controversial fisheries issues in the world – those associated with the unwanted wastage of fish from by-catch and discarding. The 8 chapters encompass contributions from 27 of the world’s leading experts in by-catch reduction. They take the reader through most aspects of the field at a variety of scales and viewpoints. They examine the methodologies used to develop by-catch reduction techniques and provide new avenues for assisting and broadening such work. Case studies are provided that encompass most of the world’s fishing techniques and regions.
Breast MRI : Diagnosis and Intervention
This superbly illustrated practical guide is an excellent resource on all aspects of breast MRI for practicing radiologists, oncologists, and surgeons, as well as residents and fellows. Drs. Elizabeth Morris and Laura Liberman, two experts in the field from the Memorial Sloan-Kettering Cancer Center, have collaborated with colleagues from their institution and selected medical centers to share their expertise. Introductory chapters are devoted to diagnosis and cover the basics of performing breast MRI exams, setting up a breast MRI program, and understanding clinical indications. Additional chapters discuss breast interventional procedures including MRI-guided needle localization, MRI-guided biopsy, and percutaneous ablation of breast cancer; MRI of breast implants.
Breast Cancer Management and Molecular Medicine : Towards Tailored Approaches
This book provides an overview of the most recent techniques, agents and approaches for breast cancer that contribute to the individualization of treatment. Current biomedical research focuses on facilitating the transfer of molecular biology knowledge into the clinical management of patients, leading to increased survival as well as improved quality of life. Particular attention is given in this book to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation.
Brain Repair
Brain Repair, addresses all relevant issues underlying the mechanisms of brain damage, brain plasticity and post-traumatic reorganisation after CNS lesions. This book is divided the three major sections that follow; cellular and molecular basis of brain repair, plasticity and reorganisation of neural networks, and experimental therapy strategies. Brain Repair is written by high profile, international experts who describe in detail the newest results from basic research and highlight new model systems, techniques and therapy approaches. Based on a careful analysis of the cellular and molecular reaction patterns of the CNS to lesions, the contributions cover possibilities for endogenous reorganisation and repair as well as exciting new therapies emerging from basic research, some of which have already been introduced into the clinics.
Botulinum Toxin in Aesthetic Medicine
This is an excellent resource for learning how to inject Botox. Even if you are a seasoned injector, I am sure you will discover tips to improve your technique. … The audience includes any physicians who use Botox in their practice. The book specifically focuses on cosmetic use of Botox, so plastic surgeons and dermatologists would be the majority of physicians interested in reading it.
Botulinum toxin
Offering a step-by-step, practical approach to this commonly performed cosmetic procedure, Procedures in Cosmetic Dermatology: Botulinum Toxin, 5th Edition, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. It covers the science behind these neuromodulators and their usage areas in cosmetic dermatology, as well as the latest treatment options—all abundantly illustrated and evidence based. A substantial video library demonstrating injection techniques helps you successfully incorporate the latest procedures into your practice.
Borrelia burgdorferi : Methods and protocols
Covers the latest advancements and techniques used to understand the fastidious bacterium, Borrelia burgdorferi, and its significance in infectious disorders by combining both conventional and cutting-edge approaches. This book covers diverse topics, including direct detection, diagnostic methods, immune response analysis, alternative model systems, advanced proteomics, social media analysis, and clinical research. It also discusses unconventional wet lab research such as content analysis, the use of ChatGPT, clinical algorithms for chronic Lyme, establishment of a pregnancy Lyme disease biobank, and investigates Lyme in pregnant women. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bone and Cartilage Engineering
Bone and Cartilage Engineering presents the theory and practice of cell-based regeneration of skeletal defects. Much of the focus is on the importance of the cell biological and biomaterial aspects for engineering a clinically relevant device. The basic key techniques for optimal engineering outcomes including cell and organ culture, biomaterial development, and bioreactor use are described in detail and highlighted by multiple figures.
Biotic elicitors: Production, purification, and characterization
Details techniques to study biotic elicitors involved in the field of agriculture for the benefit of the environment and growers. Chapters guide readers through protein, carbohydrate, lipid, glycoprotein and glycolipid components derived from microorganisms and their production, purification, and characterization.
Biotechnologies for plant mutation breeding : Protocols
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.
Biosurfactants for a sustainable future : Production and applications in the environment and biomedicine
The book emphasizes the different techniques that are used for the production of biosurfactants from microorganisms and their characterization. Various aspects of biosurfactants, including structural characteristics, developments, production, bio-economics and their sustainable use in the environment and biomedicine, are addressed, and the book also presents metagenomic strategies to facilitate the discovery of novel biosurfactants producing microorganisms.
Bioreactors for Tissue Engineering : Principles, Design and Operation
This volume addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. It also deals with the application of bioreactor technology to tissue engineering products.
Biophysical Techniques in Photosynthesis ; Vol. II
Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume (Volume 3 in the Series) by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis. The contributions are written by leading scientists in their field. The book has 5 sections: Imaging; Structure; Optical and laser spectroscopy; Magnetic resonance; Theory. Each chapter describes the basic concepts of the technique, practical applications and scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but also to assess the resources that are required for implementation. The book is intended for use by graduate students and researchers in photosynthesis as well as in (bio)physics, (bio)chemistry and biology in general.
Biopharmaceutical manufacturing progress, trends and challenges
Source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.
Biomolecular and bioanalytical techniques : Theory, methodology and applications
Offers an introduction to, and a basic understanding of, a wide range of biophysical techniques. The text takes an interdisciplinary approach with contributions from a panel of distinguished experts. With a focus on research, the text comprehensively covers a broad selection of topics drawn from contemporary research in the fields of chemistry and biology. Each of the internationally reputed authors has contributed a single chapter on a specific technique. The chapters cover the specific technique’s background, theory, principles, technique, methodology, protocol and applications.
Biomedical EPR ; Part B : Methodology, Instrumentation, and Dynamics
Biomedical EPR – Part B focuses on applications of EPR techniques and instrumentation, with applications to dynamics. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field that lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
