Dissecting the Molecular Anatomy of Tissue
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Discrete-time Sliding Mode Control : A Multirate Output Feedback Approach
Sliding mode control is a simple and yet robust control technique, where the system states are made to confine to a selected subset. With the increasing use of computers and discrete-time samplers in controller implementation in the recent past, discrete-time systems and computer based control have become important topics. This monograph presents an output feedback sliding mode control philosophy which can be applied to almost all controllable and observable systems, while at the same time being simple enough as not to tax the computer too much. It is shown that the solution can be found in the synergy of the multirate output sampling concept and the concept of discrete-time sliding mode control.
Diabetic Kidney Disease
Presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of “classic” diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease. Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments.
Design of Very High-Frequency Multirate Switched-Capacitor Circuits : Extending the Boundaries of CMOS Analog Front-End Filtering
Presents the theory and the corresponding CMOS implementation of the novel multirate sampled-data analog interpolation technique. In order to tackle physical IC imperfections at very high frequency, this work discusses the circuit design and layout techniques for high-speed Switched-Capacitor (SC) circuits.
Data science on the Google cloud platform : Implementing end-to-end real-time data pipelines : From ingest to machine learning
Learn how easy it is to apply sophisticated statistical and machine learning methods to real-world problems when you build using Google Cloud Platform (GCP). This hands-on guide shows data engineers and data scientists how to implement an end-to-end data pipeline with cloud native tools on GCP. You'll work through a sample business decision by employing a variety of data science approaches. Follow along by building a data pipeline in your own project on GCP, and discover how to solve data science problems in a transformative and more collaborative way. Employ best practices in building highly scalable data and ML pipelines on Google Cloud Automate and schedule data ingest using Cloud Run Create and populate a dashboard in Data Studio Build a real-time analytics pipeline using Pub/Sub, Dataflow, and BigQuery Conduct interactive data exploration with BigQuery Create a Bayesian model with Spark on Cloud Dataproc Forecast time series and do anomaly detection with BigQuery ML Aggregate within time windows with Dataflow Train explainable machine learning models with Vertex AI Operationalize ML with Vertex AI Pipelines
Data science in theory and practice : Techniques for big data analytics and complex data sets
Delivers a comprehensive treatment of the mathematical and statistical models useful for analyzing data sets arising in various disciplines, like banking, finance, health care, bioinformatics, security, education, and social services. Written in five parts, the book examines some of the most commonly used and fundamental mathematical and statistical concepts that form the basis of data science. The authors go on to analyze various data transformation techniques useful for extracting information from raw data, long memory behavior, and predictive modeling. Readers will also learn from topics like: Analyses of foundational theoretical subjects, including the history of data science, matrix algebra and random vectors, and multivariate analysis A comprehensive examination of time series forecasting, including the different components of time series and transformations to achieve stationarity Introductions to both the R and Python programming languages, including basic data types and sample manipulations for both languages An exploration of algorithms, including how to write one and how to perform an asymptotic analysis A comprehensive discussion of several techniques for analyzing and predicting complex data sets
Cytologic Detection of Urothelial Lesions
Cytologic Detection of Urothelial Lesions by Dorothy L. Rosenthal, MD and Stephen S. Raab, MD is the second volume in the Series. This volume will present a simple approach to dealing with cellular samples from the urinary tract.
Critical Points for the Organisation of Test Performance Studies in Microbiology : Plant Pathogens as a Case Study
This book in the field of plant pest detection shows a constant demand in development and improvement of fast and reliable detection tools, especially for high-priority pests. This open access book describes and summarizes the whole process of the organization of test performance study (TPS) for these tools. The outcome of TPS, obtained through the evaluation of the performance of one or more diagnostic tests by several laboratories on defined samples, is the finding of the best performing test/s for particular pest and for specific uses.
Creating Client Extranets with SharePoint 2003
Creating Client Extranets with SharePoint 2003 is a guide for creating client-facing extranets using SharePoint 2003. This book serves as a how-to for building full-featured extranets using SharePoint 2003 and .NET technologies. If you already have experience developing and deploying business applications in .NET, then this book will help you master the intricacies of SharePoint 2003 development and customization. This is the only book of its kind—one designed to help you build a functioning client extranet from start to finish, avoiding many inherent traps in SharePoint development. It contains numerous valuable tips, tricks, and traps. And it offers various working code samples to help you get up to speed quickly using the SharePoint object model and Web Services. It uniquely focuses on SharePoint as a corporate development platform, while other books tend to focus only on end-user features.
Conducting Quantitative Research In Education
provides a clear and straightforward guide for all those seeking to conduct quantitative research in the field of education, using primary research data samples. While positioned as less powerful and somehow inferior, non-parametric tests can be very useful where the research can only be designed to accommodate data structure which is ordinal, or scale but violates a normality assumption, which is required for parametric tests. Non-parametric data are a staple of educational research, and as such, it is essential that educational researchers learn how to work with these data with confidence and rigour.
Computer Aided Bridge Engineering : Detail Design of Pre-Stressed Concrete I-Girder / Box-Girder Bridges
Real project design calculations for a deck-girder superstructure are presented along with the design of an abutment and pier with pile foundation as the bridge substructure. The book is proposed to be read in association with processing the design work by using the computer software ASTRA Pro as referred to in the book. The book describes two essential facets of the work, which are 'Analysis of the Grillage Model of the Deck-Girder Superstructure' and the subsequent 'Design of Deck Slab and PSC I-Girder'. The software provides three facets of the work: first is the 'Analysis of the Grillage Model of the Deck-Girder Superstructure', second is the 'Design of Deck Slab and PSC I-Girder, Abutment, Piers along with Pile Foundation', and the third is a 'Set of Sample Editable CAD Drawings for the work'. The drawings may be modified as per the design work and be submitted as required for the construction. The drawings contain information on dimensions, structural detailing, bar-bending schedules, pre-stressing details and construction guides.
Computational intelligence paradigms : Innovative Applications
The book includes a sample of research on the innovative applications of advanced computational intelligence paradigms. The characteristics of computational intelligence paradigms such as learning, generalization based on learned knowledge, knowledge extraction from imprecise and incomplete data are the extremely important for the implementation of intelligent machines.
Computational intelligence in automotive applications
This volume is the first of its kind, suitable to automotive researchers, engineers and students. It provides a representative sample of contemporary CI activities in the area of automotive technology.
Computational Fluid Dynamics for Engineers
This book introduces a wide range of Computational Fluid Dynamics (CFD) methods used in the aerospace industry to solve engineering problems. Its format is arranged so that students and practicing engineers can understand the fundamental principles used in CFD, with sample computer programs for the solution of model problems. The emphasis is on two-dimensional equations in order to present the material in a modest sized book. Source codes for selected problems are given so that the reader can understand how those methods are implemented in FORTRAN and C languages, while exercises provide more hands-on experience.
Collective Action in the Formation of Pre-Modern States
This book explores a collective action perspective on the formation of pre-modern states, but does not only promote a new mode of theoretical understanding. Rather, it subjects collective action theory to a methodologically rigorous evaluation using a systematic cross-cultural analysis of historical, ethnographic, and archaeological data drawn from a world-wide sample of societies. These data provide strong support for the theory while pointing the way to a more complex and nuanced approach to collective action, uniting theories of pre-modern and modern states.
CMOS Biotechnology
"CMOS Biotechnology reviews the recent research and developments joining CMOS technology with biology. Written by leading researchers these chapters delve into four areas including: Microfluidics for electrical engineers / CMOS Actuators CMOS Electrical Sensors CMOS Optical Sensors Bioanalytical instruments have been miniaturized on ICs to study various biophenomena or to actuate biosystems. These bio-lab-on-IC systems utilize the IC to facilitate faster, repeatable, and standardized biological experiments at low cost with a small volume of biological sample. CMOS Biotechnology will interest electrical engineers, bioengineers, biophysicists as well as researchers in MEMS, bioMEMS, microelectronics, microfluidics, and circuits and systems."
Management accounting & control scales handbook
This manual is a comprehensive compilation of multi-item measures used in empirical research in the field of management accounting and control. Utz Schäffer describes all scales, including the psychometric qualities as well as samples which have been used, in great detail. Thus, the reader of this book can avoid reinventing the wheel as it will in many cases reduce the need to conceptualize, test, and validate a measure from scratch.
Long-Term Preservation of Digital Documents : Principles and Practices
Key to our culture is that we can disseminate information, and then maintain and access it over time. While we are rapidly advancing from vulnerable physical solutions to superior, digital media, preserving and using data over the long term involves complicated research challenges and organization efforts. Uwe Borghoff and his coauthors address the problem of storing, reading, and using digital data for periods longer than 50 years. They briefly describe several markup and document description languages like TIFF, PDF, HTML, and XML, explain the most important techniques such as migration and emulation, and present the OAIS (Open Archival Information System) Reference Model. To complement this background information on the technology issues the authors present the most relevant international preservation projects, such as the Dublin Core Metadata Initiative, and experiences from sample projects run by the Cornell University Library and the National Library of the Netherlands. A rated survey list of available systems and tools completes the book.
Logging in Java with the JDK 1.4 Logging API and Apache log4j
In development scenarios where things can't be run in a debugger, or when you run the risk of masking the problem, logs are the greatest source of information about running a program. Pro Apache Log4j, Second Edition provides best practices guidelines and comprehensive coverage of the most recent release. Step by step, the book explains core concepts, from basic to advanced. Code samples are in Java and include guidelines for different application-specific needs. You'll also learn how to extend the API to write custom components and best practices for using the feature-rich log4j API. This book concludes with enterprise Java applications using log4j with JSP and J2EE.
Light Scattering from Polymer Solutions and Nanoparticle Dispersions
Light scattering is a very powerful method to characterize the structure of polymers and nanoparticles in solution. Recent technical developments have strongly enhanced the possible applications of this technique, overcoming previous limitations like sample turbidity or insufficient experimental time scales. However, despite their importance, these new developments have not yet been presented in a comprehensive form. In addition, and maybe even more important to the broad audience, there lacks a simple-to-read textbook for students and non-experts interested in the basic principles and fundamental techniques of light scattering. As part of the Springer Laboratory series, this book tries not only to provide such a simple-to-read and illustrative textbook about the seemingly very complicated topic of light scattering from polymers and nanoparticles in dilute solution, but also intends to cover some of the newest technical developments in experimental light scattering.



















