الصفحة 4
الصفحة 4
Fetal and Neonatal Pathology
The book presenting the same practical approach to the examination of both fetuses and perinatal deaths. It provides essential clinical and pathophysiological information and discusses the pathogenesis of abnormalities as a basis for appropriate methods of investigation. Part 1 deals with the examination of the products of conception after the termination of pregnancy for fetal anomalies. The range of pathological abnormalities is described and their relevance discussed. Special attention is paid to the differences in pathological findings of specific conditions between the second and third trimesters. Part 2 is organised by system, describing and illustrating those pathological problems which are likely to be encountered in the fetus and neonate. Each chapter is introduced by a concise account of the development of the relevant system. There is also a discussion, as appropriate, of changes at birth as well as changes in normal function that may occur during the neonatal period.
Ferroptosis : Methods and protocols
A comprehensive collection of experimental protocols for investigating ferroptosis in different systems, including cultured cells, animal models, and human tissues. The techniques covered in this book look at various aspects of ferroptosis ranging from the detection of lipid peroxidation to the measurement of glutathione peroxidase activity and the evaluation of mitochondrial morphology. Chapters also discuss basic molecular biology methods such as quantitative PCR and immunoblotting, and advanced imaging techniques such as transmission electron microscopy and confocal fluorescence microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Fecal Incontinence : Diagnosis and Treatment
Fecal incontinence is a frequent, distressing condition that has a devastating impact on patients’ lives. However, patients are typically embarrassed and reluctant to acknowledge this disability, so they relinquish the possibility of being cured and remain socially isolated. Since fecal incontinence may result from various pathophysiological situations, an accurate diagnostic work-up of each patient is fundamental. Today, a wide range of therapeutic options is available, but making the correct choice is pivotal to the successful management of this condition. This book is aimed at all physicians involved in the assessment and treatment of fecal incontinence. Its main purpose is to review the latest advances in the epidemiologic, socio-economic, psychologic, diagnostic, and therapeutic aspects of fecal incontinence, in order to establish guidelines for effective treatment.
Farewell to the Internal Clock : A contribution in the field of chronobiology
Nearly everything making up what we call the “environment” of a plant has an infuence on the way it grows. Sunlight, te- perature, moisture contents of soil and atmosphere and vib- tions are all obvious examples of environmental components, and transient variations in their amount or intensity lead the plant to manifest more or less immediate responses. Small changes in carbon dioxide level in the atmosphere can even have effects, but these take a longer time to be registered – at least those that are visible, albeit at the microscopic level. Plants meet the challenges of the environment by means of acclimation. In this respect, plants are notable for the pl- ticity of their development. However, where morphological or physiological plasticity is no longer an option, the responses would be by means of adaptations as a result of genetic - lection or genetic “assimilation” (Waddington 1957).
Evoked Spinal Cord Potentials : An illustrated Guide to Physiology, Pharmocology, and Recording Techniques
This book surveys the neurophysiological and neuropharmacological bases of evoked SCPs with reference to animal studies and to recording those potentials mainly from the spinal epidural space. Generous use of illustrations promotes understanding of the neurophysiological and neuropharmacological backgrounds of monitoring spinal cord functions, and case studies provide additional insight into the monitoring and diagnosis of spinal cord dysfunction and disease.
Evidence-Based Endocrinology
Evidence-based medicine (EBM) stresses the use of evidence from clinical research as the basis for medical decision making, rather than simple reliance on unsystematic clinical experience and pathophysiological rationales. EBM has changed many aspects of medical practice for the better, but its incorporation into endocrine practice has been minimal.
Ethylene Action in Plants
The plant hormone ethylene plays a prominent role among several intrinsic and extrinsic factors that control growth and physiology of plants. Its biological activity was discovered over a century ago. However, extensive studies on its mode of action came later. To date, it is well documented that ethylene is a versatile signaling molecule that plays an important role in many physiological processes - like growth, senescence, fruit ripening, stress responses, symbioses, and photosynthesis. Molecular-genetic analyses have revealed mechanisms responsible for ethylene production, perception, and signal transduction. The present work brings into focus the recent developments on the biochemical, physiological, and molecular basis for ethylene action in plants.
Essentials of pharmacodynamics and drug action
Provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment.
Essential physiology for dental students
Offers comprehensive information on human physiology, tailored to the needs of students of dentistry. This new addition to the Dentistry Essentials series helps students gain a deeper understanding of how physiological concepts apply to clinical dental practice. Each chapter outlines an organ system in sufficient detail whilst emphasizing its relevance to clinical dentistry. Written in a student-friendly style, it contextualizes how normal and altered physiology affects dental care and highlights the implications of dental interventions on the body’s functioning.
Essential echocardiography : A practical guide
A Practical Handbook serves as today's premier practical guide to the understanding of the most commonly used cardiac imaging technique in the world. The perfect marriage between anatomy and physiology, the text covers emerging cardiac imaging technologies, advances in ultrasound technology, as well as new techniques and applications of cardiac ultrasound. Essential Echocardiography: A Practical Handbook provides the physiological, anatomical, and diagnostic grounding for all students of cardiac ultrasound, as well as a sound basis for a more general understanding of cardiac imaging.
Endocrinology : Basic and Clinical Principles
For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion.
Electrical Diseases of the Heart : Genetics, Mechanisms, Treatment, Prevention
Electrical Diseases of the Heart is a thorough clinical reference on the current status of cardiac electrophysiological disease,emphasizing common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology, and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science.
Effect of antioxidants in plant extracts and free radicals on blood sample
Antioxidants are substances that inhibit and regulate the formation of free radicals, and prevent or slow down the damage to cells caused by free radicals. There is a balance between antioxidants and free radicals throughout the body, and free radicals become dangerous when the balance is disturbed Free radicals play a key role in many physiological decisions in cells. Since free radicals are toxic to cellular components, it is known that they cause DNA damage, contribute to DNA instability and mutation and thus favor carcinogenesis.Low levels of free radicals and steady state levels of antioxidant enzymes are responsible for the fine tuning of redox status inside cells. A change in redox state is a way to modify the physiological status of the cell.Many healthful foods contain antioxidants. If a person consumes some or all of these foods regularly, they may increase their antioxidant levels, potentially helping them prevent the damage that doctors associate with oxidative stress.
Ecology of Tidal Freshwater Swamps of the Southeastern United States
This book draws together the latest findings from investigators focusing on the hydrological processes, community organization, and stress physiology of freshwater, tidally influenced land-margin forests of the southeastern United States. It describes the land use history that led to the restricted distribution of these wetlands, and provides descriptions of the hydrology, soils, biogeochemistry, and physiological ecology of these systems, highlighting the similarities shared among tidal freshwater forested wetlands.
Ecocardiografia clinica = Clinical echocardiography
This Atlantean is a candidate for a didactic strategy that is established and intends fornire agli specialisti, co-involves the management of cardiac malattia, strumenti communicates for the understanding of the treatment of the variegated problem of this law in everyday clinical practice. The information is precisely selected and the echocardiography is immersed in the clinical, anatomical, pathophysiological, therapeutic and chirurgical answer when used regularly.
Drugs, the brain, and behavior : The pharmacology of therapeutics and drug use disorders
Provides a comprehensive overview of the brain and explores the clinical and pharmacological issues surrounding drug abuse and dependence. Dr Brick provides definitions, historic discoveries about the nervous system, and original, eye-catching illustrations to discuss the brain/behavior relationship, basic neuroanatomy, neurophysiology, and the mechanistic actions of mood-altering drugs. Topics include: how psychoactive drugs affect cognition, behavior, and emotion; the brain/behavior relationship; the specific effects of major addictive and psychoactive drug groups; new definitions and thinking about abuse and dependence; and the medical uses of drugs, such as cannabinoids. A new chapter on biobehavioral markers explores how markers can guide the clinician in the diagnosis of some disorders. This book offers a quick reference guide which uses a balance of instruction, illustrations, tables, and formulas, that will give you a broad, lasting introduction to this intriguing subject.
Drug delivery via nasal route
Over the past 10 years, the interest in intranasal drug delivery has increased. The objective of this research is to summarize recent developments on intranasal administration for local and systemic delivery, as well as for CNS indications. Nasal delivery offers many advantages over standard systemic delivery systems, nevertheless, there are still formulation limitations and side effects to be optimized. Intranasal drug delivery in the field of drug development is an interesting delivery route for the treatment of neurological disorders. Systemic approaches often fail to efficiently supply the CNS with drugs. This research describes the anatomical, histological and physiological basis and summarizes currently approved drugs for administration via intranasal delivery. Further, the research focuses on advantages and disadvantages of intranasal applied compounds and discusses formulation aspects that need to be considered for drug development.
Drug Delivery Approaches : Perspectives from Pharmacokinetics and Pharmacodynamics
Delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes.
Drug Addiction : From Basic Research to Therapy
Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.
Digital Human Modeling : Trends in Human Algorithms
The emerging information technologies have given rise to new human patterns in terms of both physiological and psychological interactions. Human Algorithms aim to model human forms, interactions, and dynamics in this new context.
