الصفحة 4
الصفحة 4
Nanopharmaceuticals ; Vol.1 : Expectations and realities of multifunctional drug delivery systems
Reviews advances in the drug delivery field via nanovehicles or nanocarriers that offer benefits like targeted therapy and serves as a single dose magic bullet for multiple drug delivery with improved drug efficiency at a lower dose, transportation of the drug across physiological barriers as well as reduced drug-related toxicity. The chapters are written by a diverse group of international researchers from industry and academia. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
Nanoparticle-based cancer vaccines
Reviews the fundamentals of cancer vaccines, explores the role of nanotechnology in improving vaccine design and delivery, and evaluates current clinical applications, challenges, and regulatory considerations, highlighting the potential of nanoparticle-based cancer vaccines in future cancer treatment.
Nanometer technology designs high-quality delay tests
Nanometer Technology Designs: High-Quality Delay Tests discusses these challenges in detail and proposes new techniques and methodologies to improve the overall quality of the delay test for nanotechnology designs
Nanomedicine : Innovations, applications, and breakthroughs in the quest for health and medicine's future
Revolutionizing healthcare, by providing innovative solutions to some of the most challenging issues in medicine. This book provides an in-depth overview of nanoscale materials and devices that are advancing diagnostics, therapeutics, and personalized care in medical field. It focuses on nanomedicine’s impact on vaccine efficacy as well as innovative diagnosis and therapy for various type of cancer while addressing concerns about safety and toxicity. It examines how nanotechnology is enhancing drug delivery by precisely targeting medicines to specific cells or tissues, thereby increasing treatment efficacy with reduced side effects. Explores how nanoparticles are advancing medical imaging for earlier and more accurate disease detection, and how nanosensors allow real-time biomarker monitoring for faster and more reliable diagnoses. Additionally, it explores nanomedicine's role in managing cardiovascular diseases, improving bone health through nano-extracellular vesicles, and regenerative medicine, including ongoing clinical trials and ethical considerations.
Nanoformulations in Human Health: Challenges and Approaches
This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
Nanoelectronics and Photonics : From Atoms to Materials, Devices, and Architectures
Nanoelectronics and Photonics: From Atoms to Materials, Devices, and Architectures provides a description of the core elements and challenges of advanced and future information technology. By linking the materials physics and chemistry at the atomic scale with device and circuit design and performance requirements, tutorial chapters from leaders in the field present a coherent picture of theoretical and experimental research efforts and technology development in this highly interdisciplinary area.
Nano physical pharmaceutics
Nanomedicine is an emerging and rapidly evolving field, which could significantly help in early disease diagnosis, therapeutic improvement, novel therapeutic modality development, and medical expenditure reduction. The challenge remains, however, that the specially designed and carefully synthesized nanomedicines function poorly in animal verification despite great performance in vitro. A deeper understanding of the physicochemical properties of nanomedicine is the key. This book applies physical theories and models to determine the parameters for controlling the physicochemical properties of nanomedicines, including micelles, liposomes, and inorganic nanoparticles. Qualitative and quantitative relationships are established to provide guidance for nanomedicine design, characterization, and analysis. The text also compiles cutting-edge research in nanomedicine from the interdisciplinary team of the Department of Nanomedicine at Naval Medical University, China, which is currently establishing the characteristic discipline called Nano Physical Pharmaceutics. Edited by Wei Li, a prominent nanotechnology researcher, this book will appeal to anyone involved in nanotechnology, medicine, macromolecular science, biology, chemistry, and especially those with an interest in drug delivery or cancer therapy.
Multiwavelength Mapping of Galaxy Formation and Evolution ; Proceedings of the ESO Workshop Held at Venice, Italy, 13-16 October 2003
The possibilities of astronomical observation have dramatically increased over the last decade. Major satellites, like the Hubble Space Telescope, Chandra and XMM Newton, are complemented by numerous large ground-based observatories, from 8m-10m optical telescopes to sub-mm and radio facilities. As a result, observational astronomy has access to virtually the whole electromagnetic spectrum of galaxies, even at high redshifts. Theoretical models of galaxy formation and cosmological evolution now face a serious challenge to match the plethora of observational data. In October 2003, over 170 astronomers from 15 countries met for a 4-day workshop to extensively illustrate and discuss all major observational projects and ongoing theoretical efforts to model galaxy formation and evolution. This volume contains the complete proceedings of this meeting and is therefore a unique and timely overview of the current state of research in this rapidly evolving field.
Multiscale Problems in the Life Sciences : From Microscopic to Macroscopic
The aim of this volume that presents Lectures given at a joint CIME and Banach Center Summer School, is to offer a broad presentation of a class of updated methods providing a mathematical framework for the development of a hierarchy of models of complex systems in the natural sciences, with a special attention to Biology and Medicine. Mastering complexity implies sharing different tools requiring much higher level of communication between different mathematical and scientific schools, for solving classes of problems of the same nature. Today more than ever, one of the most important challenges derives from the need to bridge parts of a system evolving at different time and space scales, especially with respect to computational affordability. As a result the content has a rather general character; the main role is played by stochastic processes, positive semigroups, asymptotic analysis, kinetic theory, continuum theory and game theory.
Multiscale Methods in Science and Engineering
Multiscale problems naturally pose severe challenges for computational science and engineering. The smaller scales must be well resolved over the range of the larger scales. Challenging multiscale problems are very common This volume is an overview of current mathematical and computational methods for problems with multiple scales with applications in chemistry, physics and engineering.
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
Multi-processor system-on-chip 1 : Architectures
covers the key components of MPSoC: processors, memory, interconnect and interfaces. It describes advance features of these components and technologies to build efficient MPSoC architectures. All the main components are detailed: use of memory and their technology, communication support and consistency, and specific processor architectures for general purposes or for dedicated applications.
Multi-point Interaction with Real and Virtual Objects
This edited book covers some of the most challenging problems on the forefront of today’s research on physical interaction with real and virtual objects, with special emphasis on modelling contacts between objects, grasp planning algorithms, haptic perception, and advanced design of hands, devices and interfaces.
Multiple Stressors : A Challenge for the Future
This book publishes the Proceedings of the NATO Advanced Research Workshop on Multipollution Exposure and Risk Assessment, Ecotoxiclogical risk from multiple stressors covers any situation where org- isms are exposed to a combination of environmental stressors. These include physical and chemical pollutants as well as other stressors such as parasites and environmental impact (e. g. , climate change or habitat loss). The combi- tion of stressors can result in increased risk to organisms (either additive or synergistic effects) or decreased effects (protective or antagonistic effects). The multiple stressor challenge is an international, multi-disciplinary problem requiring an international, multi-disciplinary approach. The c- rent approach to multiple stressors is to examine one stressor at a time and assume additivity.
Multiple Stars Across the H-R Diagram ; Proceedings of the ESO Workshop held in Garching, Germany, 12-15 July 2005
Stars show a marked tendency to be in systems of different multiplicity, ranging from simple binaries and triples to globular clusters with several 10,000's of stars. The formation and evolution of multiple systems remains a challenging part of astrophysics, and the contributions in this book report on the significant progress that had been made in this research field in the last years. The reader will find a variety of research topics addressed, such as the dynamical evolution in multiple stars, the effects of the environment on multiple system parameters, stellar evolution within multiple stars, multiplicity of massive stars, pre-main sequence and intermediate mass stars, multiplicity of low-mass stars from embedded protostars to open clusters, and brown dwarfs and extrasolar planets in multiples.
Multiple Heterogeneous Unmanned Aerial Vehicles
Aerial robots can be considered as an evolution of the Unmanned Aerial Vehicles (UAVs). This book provides a quite complete overview of issues related to aerial robotics, addressing problems ranging from flight control to terrain perception and mission planning and execution. The major challenges and potentials of heterogeneous UAVs are comprehensively explored. It builds on the results of the European project COMETS, and highlights a number of key research topics in the area of UAV development, including communication, perception, teleoperation and decision making. The monograph emphasizes the current state of technology, the existing problems and potentialities of systems consisting of multiple UAVs which are heterogeneous in view of the different characteristics of the aerial vehicles, the different on-board payloads, and the different on-board information processing capabilities. The book also examines potential applications of UAVs and details a relevant application case: forest fire detection and monitoring.
Multiple Classifier Systems ; 2nd International Workshop, MCS 2001 Cambridge, UK, July 2-4, 2001 Proceedings
Driven by the requirements of a large number of practical and commercially - portant applications, the last decade has witnessed considerable advances in p- tern recognition. Better understanding of the design issues and new paradigms, such as the Support Vector Machine, have contributed to the development of - proved methods of pattern classi cation. However, while any performance gains are welcome, and often extremely signi cant from the practical point of view, it is increasingly more challenging to reach the point of perfection as de ned by the theoretical optimality of decision making in a given decision framework. The asymptoticity of gains that can be made for a single classi er is a re?- tion of the fact that any particular design, regardless of how good it is, simply provides just one estimate of the optimal decision rule.
Multiobjective Optimization : Interactive and Evolutionary Approaches
Multiobjective optimization deals with solving problems having not only one, but multiple, often conflicting, criteria. Such problems can arise in practically every field of science, engineering and business, and the need for efficient and reliable solution methods is increasing. The task is challenging due to the fact that, instead of a single optimal solution, multiobjective optimization results in a number of solutions with different trade-offs among criteria, also known as Pareto optimal or efficient solutions. Hence, a decision maker is needed to provide additional preference information and to identify the most satisfactory solution. Depending on the paradigm used, such information may be introduced before, during, or after the optimization process. Clearly, research and application in multiobjective optimization involve expertise in optimization as well as in decision support.
Multinational Enterprises, Foreign Direct Investment and Growth in Africa : South African Perspectives
How can Africa, the world’s most lagging region, benefit from globalisation and achieve sustained economic growth? Africa needs greater investment by Multinational Enterprises (MNEs) to improve competitiveness and generate more growth through positive spill-over effects. Despite the fact that Africa’s returns on investment averaged 29% since 1990, Africa has gained merely 1% of global Foreign Direct Investment (FDI) flows. The challenge for African countries is how to be a more desirable destination for FDI. The study integrates three currents of economic research, namely from the literature on (endogenous) economic growth, convergence and regional integration, the explanations for Africa’s poor growth and the growing understanding of the role of MNEs in a global economy. The empirical side of the book is based on an econometric study of the determinants of FDI in Africa as well as a detailed firm-level survey conducted in 2000.
Multimodality in architecture : Collaboration, technology and education
Examines multimodality in architecture and its impacts on collaborative, technical and educational processes or systems. Multimodality is becoming increasingly critical in contemporary architectural practice and education. Creative design teams face new challenges when they embrace new modes of communication, technology, and knowledge development processes. From diverse online modes of communication to shared digital environments, generative AI and advanced hardware solutions, new modes of information creation, sharing, and application are changing the ways architects and designers work. The book presents new research which empowers international researchers and designers to work more effectively in a diverse range of digital environments. Whether the readers are architects, teachers, students, or scholars, this book provides critical insights and practical tools for understanding and optimising processes in architecture and design.
