الصفحة 39
الصفحة 39
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Diplomacy and International Law in Globalized Relations

"The art of diplomacy has thoroughly changed in the age of globalization. Foreign policy is no longer the domain of relations among states, but is practiced by international organizations, transnational companies, and non-governmental organizations alike. This book explores the changing role of diplomacy in a globalizing world. It serves as an eye opener for anybody interested in the practice of international negotiations, written by one of the most experienced senior diplomats of the German foreign service."

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Dipeptidyl Aminopeptidases : Basic Science and Clinical Applications

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.

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Dioxygen Binding and Sensing Proteins : A Tribute to Beatrice and Jonathan Wittenberg

Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments.This book is dedicated to Jonathan’s and Bea’s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.

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Digital darwinism : Surviving the new age of business disruption

This book guides you through the unrelenting pace of change and uncertainty facing business leaders today. Currently in a hybrid world where digital and real-world experiences collide and are expected to seamlessly blend into one another, never has the need to be on top of your digital transformation been felt more strongly.

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Diffuse matter from star forming regions to active galaxies : A volume honouring John Dyson

In this volume dedicated to him, introductory reviews to a number of the key processes and to the sources themselves are given by leading experts. The mechanisms in which the multi-component natures of media affect their dynamics receive particular attention, but the roles of hydromagnetic effects are also highlighted.

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Diastolic Heart Failure

This book addresses the epidemiology, pathophysiologic mechanisms, diagnostic methods, treatment and prognosis. It also gives an analysis of specific problems, related to coronary artery disease, arterial hypertension, diabetes, hypertrophic and restrictive cardiomyopathies, and constrictive pericarditis.

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Diapause in Aquatic Invertebrates : Theory and Human Use

Contributors to this new book are leaders in the field of diapause studies, and many authors were participants at a recent workshop on diapause in aquatic invertebrates (Pallanza, Italy 2003). The book consists of two major parts, as indicated in its title: Phenomenology of diapause and significance of this adaptation in scientific and practical uses. Application to newly developing areas such as cultivation of live food, like rotifers or Artemia, in modern aquaculture is covered, as are aspects of diapause that promote the colonization of new environments by facilitating the passive transport of resting stages of invasive species. Creation of artificial ecosystems outside of the Earth’s biosphere using dormant propagules becomes an actual possibility as humankind develops plans to colonize our nearest planets.

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Diagrammatology : An investigation on the borderlines of phenomenology, ontology, and semiotics

Diagrammatology investigates the role of diagrams for thought and knowledge. Based on the general doctrine of diagrams in Charles Peirce's mature work, Diagrammatology claims diagrams to constitute a centerpiece of epistemology. The book reflects Peirce's work on the issue in Husserl's contemporanous doctrine of "categorial intuition" and charts the many unnoticed similarities between Peircean semiotics and early Husserlian phenomenology. Diagrams, on a Peircean account, allow for observation and experimentation with ideal structures and objects and thus furnish the access to the synthetic a priori of the regional and formal ontology of the Husserlian tradition.

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Diagnostic Nuclear Medicine

The present text, supplemented with many detailed and informative illustrations, represents an adjunct to the standard knowledge of diagnostic nuclear medicine and provides both the student and the professional with an overview of developments during the past decade.

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Diagnosis of pathogenic microorganisms : Causing infectious diseases

Infectious diseases are caused by the pathogenic microbial organisms. These microbes can multiply and can cause an infection, once they enter the body. Infectious diseases are transmissible, and may cause mild to life-threatening illnesses. It can be airborne, waterborne, foodborne, and soilborne. It can be spread through direct contact (human to human, animal to human). It has also been one of the leading causes of human deaths. Therefore, there is a need to have rapid diagnostic methods to prevent and control these diseases. This book titled “Diagnosis of Pathogenic Microorganisms Causing Infectious Diseases” will help the scientific community to understand the transmission dynamics of some infectious diseases of public health importance.

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Diabetes mellitus and bacterial and fungal urinary tract infection

Diabetes mellitus is a heterogeneous group of disorders characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. Patients with type 2 diabetes mellitus are at increased risk of infections, with the urinary tract being the most frequent infection site. Various impairments in the immune system, in addition to poor metabolic control of diabetes, and incomplete bladder emptying due to autonomic neuropathy, may all contribute in the pathogenesis of urinary tract infections (UTI) in diabetic patients. Factors that were found to enhance the risk for UTI in diabetics include age, metabolic control, and long-term complications, primarily diabetic nephropathy and cystopathy. The spectrum of UTI in these patients ranges from asymptomatic bacteriuria (ASB) to lower UTI (cystitis), pyelonephritis, and severe urosepsis.

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Diabetes Mellitus & Recent developments

Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defect in insulin secretion, insulin action, or both. Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia, and blurred vision. Frequency of diabetic in the world About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic Classification Of Diabetic Mellitus. 1-Type 1 diabetes: which accounts for only5–10% of those with diabetes, results from a cellular-mediated autoimmune destruction of the cells of the pancreas. 2-Type 2 diabetes: which accounts for90 –95% of those with diabetes, result from insulin resistance. The chronic complications of diabetes mellitus affect many organ systems and are responsible for the majority of morbidity and mortality. Such as, retinopathy, diabetic foot, neuropathy, and nephropathy, sexual dysfunction, and skin changes.

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Developmental Biology of Neoplastic Growth

In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.

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Development of trans-free lipid systems and their use in food products

Encompasses the work of leading researchers discussing, from a scientific and technological perspective, the latest and most innovative approaches to structure edible oils without the use of trans fats. Additionally, the authors discuss practical uses and technical limitations associated with the use of "structured edible oils" in different food systems. Appealing to researchers and professionals working in lipid science, food chemistry and fat metabolism, it fills the gap in the literature for a book in this fast-changing field.

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Detection of Liquid Explosives and Flammable Agents in Connection with Terrorism

The organization of an Advanced Research Workshop with the title “Detection and Disposal of Liquid Explosives and Flammable Agents in Connection with Terrorism” was motivated by international findings about activities in this field of application. This ARW followed a meeting about the “Detection of Disposal Improvised Explosives” (St. Petersburg, 2005). Both items show the logistic problems as one of the lessons, terrorists have to overcome. These problems are connected with the illegal supply and transport of explosives and fuels and as counter-measure the detection of these materials. The invention of liquid explosives goes back to the middle of the 19th century and was used for special purposes in the commercial field of application. Because of the high sensitivity of liquid explosives against mechanical shock, caused by adiabatic compression of air-bobbles producing “hot spots” as origin of initiation the commercial application was not very successful. Because of this high risk, liquid explosives are not used in military or commercial application with some exceptions. In the commercial field explosives as slurries or emulsions consisting of suitable salts (Ammoniumnitrate etc.) and water are used to a large extend because of their high insensitivity. In many cases these slurries or emulsions were unfit for terrorist actions, because of their low sensitivity, large critical diameter and using in confinement. In the military field liquid explosives are used in World War I and II as bomb-fillings.

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Designing tall buildings : Structure as architecture

Advises you to consider the influence of a particular site's geology, wind conditions, and seismicity. Using this contextual knowledge and analysis, you can determine what types of structural solutions are best suited for a tower on that site. You can then conceptualize and devise efficient structural systems that are not only safe, but also constructible and economical. Sarkisian also addresses the influence of nature in design, urging you to integrate structure and architecture for buildings of superior performance, sustainability, and aesthetic excellence.

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Designing sustainable cities

Emphasizes new ways of designing for a sustainable city and urban environment. From several angles the future of our urbanism is illuminated. From a philosophical point of view, the city is seen as an organism, following complex ecosystemic principles, shining light on indigenous perspectives to become beneficial for sustainable design and core questions are asked whether current architectural practice is really sustainable. Simultaneously concrete practices are presented for cities in transformation, focusing on green infrastructure, smart city principles and health.

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Designing Organizations : 21st Century Approaches

The design of organizations has been an ongoing concern of management theory and practice over the past several decades. Over this time, there has been little change in the fundamental theory, principles and concepts of Organization Design (OD). Recently organizational life has changed dramatically with the advent of: new communication systems, adaptive mechanisms, information technology, knowledge management systems, innovation processes and more. This book systemically examines these developments and their impact on OD with contributions from leading scholars in the area. Also featured in the book are the practical issues with implementing OD in organizations. The individual chapters are organized into five sections: (1) Putting Contingency Theory in its Place, (2) Focus on Individuals Who Make up the Organization, (3) Innovation Processes and Organization Design, (4) Adaptation and Technology, and (5) Design for Performance. Each chapter examines aspects of the book’s threefold theme: (1) core issues in organization design, (2) emerging theoretical perspectives in OD, and (3) new developments and directions in OD. A special feature of each chapter is: 1) implications for theory, and 2) implications for practice.

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Designing Democracy : Ideas for Better Rules

While liberal democracies are the best systems of self-governance for societies, they rarely invoke great enthusiasm. On the one hand, democracies have been known to fail in achieving efficient or fair allocations. On the other hand, many citizens take the democratic system for granted as they have yet to experience an alternative. In this book the vision we propose is that the potential of democ­ racies has not yet been exhausted, and that optimal democracies are both the Utopia for societies and the aim that scientists should be committed to. We present a number of ideas for drawing up new rules to im­ prove the functioning of democracies. The book falls into two parts. The first part examines ways of combining incentive contracts with democratic elections. We suggest that a judicious combina­ tion of these two elements as a dual mechanism can alleviate a wide range of political failures, while at the same time adhering to the founding principles of democracies. The second part presents new rules for decision-making and agenda setting. Together with modern communication devices, these rules can sometimes transcend the limitations of liberal VI Preface democracies in achieving desirable outcomes. Examples of such rules include the flexible majority rule where the size of the ma­ jority required depends on the proposal, or the rule that only those belonging to the winning majority can be taxed.

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Design of Very High-Frequency Multirate Switched-Capacitor Circuits : Extending the Boundaries of CMOS Analog Front-End Filtering

Presents the theory and the corresponding CMOS implementation of the novel multirate sampled-data analog interpolation technique. In order to tackle physical IC imperfections at very high frequency, this work discusses the circuit design and layout techniques for high-speed Switched-Capacitor (SC) circuits.

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