الصفحة 37
الصفحة 37
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Deciphering Growth

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.

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Databases, Information Systems, and Peer-to-Peer Computing ; International Workshops, DBISP2P 2005/2006, Trondheim, Norway, August 28-29, 2006, Revised Selected Papers

The P2P paradigm lends itself to constructing large-scale, complex, adaptive, autonomous and heterogeneous database and information systems, endowed with clearly specified and difierential capabilities to negotiate, bargain, coordinate and self-organize the information exchanges in large-scale networks. This vision will have a radical impact on the structure of complex organizations (business, sci- tific or otherwise) and on the emergence and the formation of social communities, and on how the information is organized and processed. The P2P information paradigm naturally encompasses static and wireless connectivity and static and mobile architectures. Wireless connectivity combined with the increasingly small and powerful mobile devices and sensors poses new challenges as well as opp- tunities to the database community. Information becomes ubiquitous, highly distributed and accessible anywhere and at any time over highly dynamic, - stable networks with very severe constraints on the information management and processing capabilities.

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Databases, information systems, and peer-to-peer computing ; 2nd international workshop, DBISP2P 2004, Toronto, Canada, August 29-30, 2004, revised selected papers

Peer-to-peer (P2P) paradigm lends itself to constructing large-scale complex, adaptive, - tonomous and heterogeneous database and information systems, endowed with clearly speci?ed and di?erential capabilities to negotiate, bargain, coordinate, and self-organize the information exchanges in large-scale networks. This vision will have a radical impact on the structure of complex organizations (business, scienti?c, or otherwise) and on the emergence and the formation of social c- munities, and on how the information is organized and processed. The P2P information paradigm naturally encompasses static and wireless connectivity, and static and mobile architectures. Wireless connectivity c- bined with the increasingly small and powerful mobile devices and sensors pose new challenges to as well as opportunities for the database community. Inf- mation becomes ubiquitous, highly distributed and accessible anywhere and at any time over highly dynamic, unstable networks with very severe constraints on the information management and processing capabilities.

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Database Theory – ICDT 2007 ; 11th International Conference, Barcelona, Spain, January 10-12, 2007, Proceedings

The papers are organized in topical sections on information integration and peer to peer, axiomatizations for XML, expressive power of query languages, incompleteness, inconsistency, and uncertainty, XML schemas and typechecking, stream processing and sequential query processing, ranking, XML update and query, as well as query containment.

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Database systems for advanced applications ; Vol. 3453 ; 10th international conference, DASFAA 2005, Beijing, China, April 17-20, 2005, Proceedings

Data Stream Mining and Resource Adaptive Computation.- Purpose Based Access Control for Privacy Protection in Database Systems.- Complex Networks and Network Data Mining.- Bioinformatics.- Indexing DNA Sequences Using q-Grams.- PADS: Protein Structure Alignment Using Directional Shape Signatures.- LinkageTracker: A Discriminative Pattern Tracking Approach to Linkage Disequilibrium Mapping.- Watermarking and Encryption.- Query Optimization in Encrypted Database Systems.- Watermarking Spatial Trajectory Database.- Effective Approaches for Watermarking XML Data.- XML Query Processing.- A Unifying Framework for Merging and Evaluating XML Information.- Efficient Evaluation of Partial Match Queries for XML Documents Using Information Retrieval Techniques.- PathStack: A Holistic Path Join Algorithm for Path Query with Not-Predicates on XML Data.- XML Coding and Metadata Management.- An Improved Prefix Labeling Scheme: A Binary String Approach for Dynamic Ordered XML.- Efficiently Coding and Indexing XML Document.- XQuery-Based TV-Anytime Metadata Management.- Data Mining.- Effective Database Transformation and Efficient Support Computation for Mining Sequential Patterns.

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Data Warehousing and Knowledge Discovery ; 9th International Conference, DaWaK 2007, Regensburg, Germany, September 3-7, 2007, Proceedings

Data Warehousing and Knowledge Discovery have been widely accepted as key te- nologies for enterprises and organizations to improve their abilities in data analysis, decision support, and the automatic extraction of knowledge from data. With the exponentially growing amount of information to be included in the decision-making process, the data to be processed become more and more complex in both structure and semantics. Consequently, the process of retrieval and knowledge discovery from this huge amount of heterogeneous complex data constitutes the reality check for research in the area.

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Data science in theory and practice : Techniques for big data analytics and complex data sets

Delivers a comprehensive treatment of the mathematical and statistical models useful for analyzing data sets arising in various disciplines, like banking, finance, health care, bioinformatics, security, education, and social services. Written in five parts, the book examines some of the most commonly used and fundamental mathematical and statistical concepts that form the basis of data science. The authors go on to analyze various data transformation techniques useful for extracting information from raw data, long memory behavior, and predictive modeling. Readers will also learn from topics like: Analyses of foundational theoretical subjects, including the history of data science, matrix algebra and random vectors, and multivariate analysis A comprehensive examination of time series forecasting, including the different components of time series and transformations to achieve stationarity Introductions to both the R and Python programming languages, including basic data types and sample manipulations for both languages An exploration of algorithms, including how to write one and how to perform an asymptotic analysis A comprehensive discussion of several techniques for analyzing and predicting complex data sets

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Data Science for Civil Engineering : A Beginner's Guide

Explains use of data science-based techniques for modeling and providing optimal solutions to complex problems in civil engineering. It discusses civil engineering problems like air, water and land pollution, climate crisis, transportation infrastructures, traffic and travel modes, mobility services, and so forth. Divided into two sections, the first one deals with the basics of data science and essential mathematics while the second section covers pertinent applications in structural and environmental engineering, construction management, and transportation.

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Data Monitoring in Clinical Trials : A Case Studies Approach

Randomized clinical trials are the gold standard for establishing many clinical practice guidelines and are central to evidence based medicine. Obtaining the best evidence through clinical trials must be done within the boundaries of rigorous science and ethical principles. One fundamental principle is that trials should not continue longer than necessary to reach their objectives. Therefore, trials must be monitored for recruitment progress, quality of data, adherence to patient care or prevention standards, and early evidence of benefit or harm. Frequently, a group of external experts, independent from the investigators and trial sponsor, is charged with this monitoring responsibility, especially for safety and early benefit. This group is referred to by various names, such as a data monitoring committee or a data and safety monitoring board. This book, through a series of case studies presented by many distinguished clinical trial experts, illustrates the complexity of this monitoring process.No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included. This series of cases should provide broad background information for potential monitoring committee members and better prepare them for the challenges that may exist in the trials for which they are responsible.

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Data Mining : Foundations and Practice

This book contains valuable studies in data mining from both foundational and practical perspectives. The foundational studies of data mining may help to lay a solid foundation for data mining as a scientific discipline, while the practical studies of data mining may lead to new data mining paradigms and algorithms.

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Data Management. Data, Data Everywhere ; 24th British National Conference on Databases, BNCOD 24, Glasgow, UK, July 3-5, 2007, Proceedings

One of the most pressing challenges is to ?nd ways of evolving database technology to cope with its new role in underpinning the massively distributed and heterogeneous applications built on top of the Internet. This has afiected both the ways in which data has been accessed and the ways in which it is represented, with XML data management becoming an important issue and, as such, heavily represented at this conference. It has also brought back issues of performance that might have been considered largely solved by the improvements in hardware, since data now has to be managed on devices of low power and small memory as well as on standard client and powerful server machines. We therefore invited papers on all aspects of data management, particularly related to how dataisused in the ubiquitous environment of the modern Internet by complex distributed and scientific applications.

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Data Complexity in Pattern Recognition

Data Complexity in Pattern Recognition is unique in its comprehensive coverage and multidisciplinary approach from various methodological and practical perspectives. Researchers and practitioners alike will find this book an insightful reference to learn about the current status of available techniques as well as application areas.

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Data and applications security XXII ; 22nd Annual IFIP WG 11.3 Working Conference on data and applications security London, UK, July 13-16, 2008 Proceedings

This volume contains the papers presented at the 22nd Annual IFIP WG 11.3 Working Conference on Data and Applications Security (DBSEC) held in L- don, UK, July 13–16, 2008.

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Data Analysis, Classification and the Forward Search ; Proceedings of the Meeting of the Classification and Data Analysis Group (CLADAG) of the Italian Statistical Society, University of Parma, June 6-8, 2005

This book presents new developments in data analysis, classification and multivariate statistics, and in their algorithmic implementation. The volume offers contributions to the theory of clustering and discrimination, multidimensional data analysis, data mining, and robust statistics with a special emphasis on the novel Forward Search approach. Many papers provide significant insight in a wide range of fields of application. Customer satisfaction and service evaluation are two examples of such emerging fields.

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Cyclized Helical Peptides : Synthesis, Properties and Therapeutic Applications

Constraint helical peptides have emerged as a solution to target previously undruggable protein-protein interactions, which feature large and complex surfaces. Cyclized Helical Peptides: Synthesis, Properties and Therapeutic Applications offers a review of the most current methodologies of constructing constrained helices. The authors noted experts on the topic include the information on the fundamental features of cyclized helical peptides and discuss their limitations. The book summarizes and explores the effects of chemical methods constructing helical peptides on helicity, binding affinity, cell penetration, and nonspecific toxicity

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Cycle Spaces of Flag Domains : A Complex Geometric Viewpoint

This monograph, divided into four parts, presents a comprehensive treatment and systematic examination of cycle spaces of flag domains. Assuming only a basic familiarity with the concepts of Lie theory and geometry, this work presents a complete structure theory for these cycle spaces, as well as their applications to harmonic analysis and algebraic geometry.

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Cyber-physical systems of systems : Foundations : A conceptual model and some derivations : The AMADEOS legacy

Technical Systems-of-Systems (SoS) – in the form of networked, independent constituent computing systems temporarily collaborating to achieve a well-defined objective – form the backbone of most of today’s infrastructure. The energy grid, most transportation systems, the global banking industry, the water-supply system, the military equipment, many embedded systems, and a great number more, strongly depend on systems-of-systems. The correct operation and continuous availability of these underlying systems-of-systems are fundamental for the functioning of our modern society.

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Cybernetical Physics : From Control of Chaos to Quantum Control

This book is, perhaps, the first attempt to present a unified exposition of the subject and methodology of cybernetical physics as well as solutions to some of its problems. Emphasis of the book is on the examination of fundamental limits on energy transformation by means of control procedures in both conservative and dissipative systems.

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Current Concepts in Autoimmunity and Chronic Inflammation

The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. This book explores clinical and experimental evidence suggesting that the importance of an individual factor changes during the course of the disease.

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Cultural Linguistics and World Englishes

This book investigates the study of World Englishes from the perspective of Cultural Linguistics, a theoretical and analytical framework for cultural cognition, cultural conceptualisations and language that employs and expands on the analytical tools and theoretical advancements in a number of disciplines, including cognitive psychology/science, anthropology, distributed cognition, and complexity science.

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