الصفحة 34
الصفحة 34
Entry Inhibitors in HIV Therapy
The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present.
English for Everyone Junior Beginner's Practice Book : Look, Listen, Learn, and Practise
Featuring hundreds of exercises, this practice book tests all the vocabulary and grammar structures taught in the English for Everyone Junior: Beginner's Course, making use of a range of both familiar and new exercise mechanisms.
English as a foreign language for Deaf and hard of hearing learners : Teaching strategies and interventions
The chapters cover a wide range of interventions and strategies including early education teaching strategies, using sign -bilingualism in the classroom, enhancing oral communication, speech visualization, improving pronunciation, using films and cartoons, lip reading techniques, written support, and harnessing writing as a memory strategy.
Energy Metabolism and Obesity : Research and Clinical Applications
Elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them.
Energy branding : Harnessing consumer power
Demonstrating the potential of building strong brands in the energy sector, This book explores the challenges of shifting the perception of energy from a commodity business into a consumer brand. Energy suppliers are increasingly being met with skepticism, indicating the need for a greater focus on marketing and branding in the energy industry. The author examines both perspectives of energy as a commodity business and a consumer brand, as well as the perception of energy consumers across Europe. Topics discussed include green energy, the liberalisation of the electricity industry, and the relationship between consumers and executives in the energy market.
Endurance time excitation functions : Intensifying dynamic loads for seismic analysis and design
Seismic assessment and earthquake-resistant design are essential applications of earthquake engineering for achieving seismic safety for buildings, bridges, infrastructure, and many other components of the built environment. The Endurance Time Method (ETM) is used for seismic analysis of simple and complex structural systems and civil engineering infrastructure as well as producing optimal and cost-effective structural and detail designs. ETM is a relatively new approach to seismic assessment and design of structures. It has developed into a versatile tool in the field, and its practical applications are expected to increase greatly in the near future.
End-to-End Quality of Service Over Heterogeneous Networks
The book presents mechanisms, protocols, and system architectures to achieve end-to-end Quality-of-Service (QoS) over heterogeneous wired/wireless networks in the Internet. Particular focus is on measurement techniques, traffic engineering mechanisms and protocols, signalling protocols as well as transport protocol extensions to support fairness and QoS. It shows how those mechanisms and protocols can be combined into a comprehensive end-to-end QoS architecture to support QoS in the Internet over heterogeneous wired/wireless access networks. Finally, techniques for evaluation of QoS mechanisms such as simulation and emulation are presented.
Endophytic microbes: Isolation, identification, and bioactive potentials
Provides basic insight and protocols relating to endophytic microbes. Chapter are divided into five major sections detailing basic isolation, bioactive metabolites production. endophytism, isolation and identification of endophytes, bioactive potentials, and screening of metabolites.
Endocrinology : Basic and Clinical Principles
For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion.
Endocrine-Disrupting Chemicals : From Basic Research to Clinical Practice
This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
Encyclopedia of Molecular Pharmacology
It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Encyclopedia of Molecular Pharmacology
Covers all aspects of pharmacology, from the chemistry of drugs and the biochemistry of drug targets to the clinical application of drugs, with emphasis on molecular mechanisms. It also includes techniques for describing the effects of drugs and characterizing drug targets. With over 2,000 entries and 350 detailed essays by leading experts, this book is also an up-to-date and important reference for scientists in fields outside pharmacology, students, health care workers, teachers, physicians, and laypersons.
Encyclopedia of Geomagnetism and Paleomagnetism
Consisting of more than 300 articles written by ca 200 leading experts, this authoritative reference encompasses the entire fields of Geomagnetism and Paleomagnetism in a single volume. It describes in fine detail at an assessable level the state of the current knowledge and provides an up-to-date synthesis of the most basic concepts. As such, it will be an indispensable working tool not only for geophysicists and geophysics students but also for geologists, physicists, atmospheric and environmental scientists, and engineers.
Emerging Threats to Energy Security and Stability; Proceedings of the NATO Advanced Research Workshop on Emerging Threats to Energy Security and Stability, London, United Kingdom, from 23 to 25 January 2004
In particular, it sought to assess emerging threats to energy security and stability and discuss new security strategies to protect global energy supplies from regional instability and terrorism. The format involved a wide-ranging international group of poli- formers and advisers from NATO, Partner and other countries, in a unique forum for intensive expert discussion. Background The international community is increasingly conscious of the need to develop new energy security strategies in order to protect global energy supplies from regional instability and terrorism. Energy security is a vital element in international stability. However, a variety of energy-related economic, technical, and military/political factors pose serious challenges to the international community’s pursuit of energy security and stability: The global economy is expected to continue to be largely dependent on oil and gas for the next twenty to thirty years.
Emerging Technologies and Information Systems for the Knowledge Society ; 1st World Summit on the Knowledge Society, WSKS 2008, Athens, Greece, September 24-26, 2008. Proceedings
This book, in conjunction with the volume CCIS 19, constitutes the refereed proceedings of theFirst World Summit, WSKS 2008, held in Athens, Greece, in September 2008.
Emerging Organic Pollutants in Waste Waters and Sludge
Over the past fifteen years regulatory agencies have relied on their approaches to characterise and control the release of toxic substances into the aquatic environment: a GC/MS analysis for U.S. EPA designated 126 priority pollutants and 132 dangerous substances according to the European 76/464/CEE Directive and on the bioassays with aquatic bioorganisms. "Emerging Contaminants" correspond in most cases to irregulated contaminants, e.g. surfactants, pharmaceuticals and personal care products (PPCP), or gasoline additives. These two volumes, 5/I and 5/O, of this Handbook deal with the analytical, toxicological and environmental issues of these toxicants. Based on results of up-to-date research they give the reader a balanced view on this rapidly developing and complex subject.
Emergent Computation : Emphasizing Bioinformatics
Emergent Computation is concerned with recent applications of Mathematical Linguistics or Automata Theory. This subject has a primary focus upon ""Bioinformatics"" (the Genome and arising interest in the Proteome), but the closing chapter also examines applications in Biology, Medicine, Anthropology, etc. The book is composed of an organized examination of DNA, RNA, and the assembly of amino acids into proteins. Rather than examine these areas from a purely mathematical viewpoint (that excludes much of the biochemical reality), the author uses scientific papers written mostly by biochemists based upon their laboratory observations. Thus while DNA may exist in its double stranded form, triple stranded forms are not excluded. Similarly, while bases exist in Watson-Crick complements, mismatched bases and abasic pairs are not excluded, nor are Hoogsteen bonds. Just as there are four bases naturally found in DNA, the existence of additional bases is not ignored, nor amino acids in addition to the usual complement of 20. Can there be more than ""64"" possible codons? RNA is examined from the point of view of Nussinov plots.
Emergence of Communication and Language
This volume brings together studies from diverse disciplines, showing how they can inform and stimulate each other. It includes work in linguistics, psychology, neuroscience, anthropology and computer science. New empirical work is reported on both human and animal communication, using some novel techniques that have only recently become viable. A principal theme is the importance of studies involving artificial agents, their contribution to the body of knowledge on the emergence of communication and language, and the role of simulations in exploring some of the most significant issues. A number of different synthetic systems are described, demonstrating how communication can emerge in natural and artificial organisms. Theories on the origins of language are supported by computational and robotic experiments. Worldwide contributors to this volume include some of the most influential figures in the field, delivering essential reading for researchers and graduates in the area, as well as providing fascinating insights for a wider readership.
Elliptic Theory and Noncommutative Geometry : Nonlocal Elliptic Operators
This comprehensive yet concise book deals with nonlocal elliptic differential operators, whose coefficients involve shifts generated by diffeomorophisms of the manifold on which the operators are defined. The main goal of the study is to relate analytical invariants (in particular, the index) of such elliptic operators to topological invariants of the manifold itself. This problem can be solved by modern methods of noncommutative geometry. This is the first and so far the only book featuring a consistent application of methods of noncommutative geometry to the index problem in the theory of nonlocal elliptic operators. Although the book provides important results, which are in a sense definitive, on the above-mentioned topic, it contains all the necessary preliminary material, such as C*-algebras and their K-theory or cyclic homology.
Elevating video content creation with ai assistance = ارتقاء إنشاء محتوى الفيديو بمساعدة الذكاء الاصطناعي
We developed an AI Assistant equipped with features such as description crafting, title generation, keyword extraction, image captioning, clickbait detection, and sentiment analysis.To achieve these functionalities, we proposed a model for generating video descriptions using ResNet50 as a feature extractor and a LSTM network with an attention mechanism as a sequence generator, achieving a BLEU-1 score of 0.907 and a ROUGE-L score of 0.645. For keyword extraction, we utilized Sentence Transformer to identify strategically relevant keywords from the generated descriptions. For title generation, we fine-tuned the BART model, achieving a ROUGE-L score of 0.45. For clickbait detection, we used SVC classifier with linear kernel and TF-IDF vectorization for feature extraction, resulting in 96% accuracy. Our sentiment analysis model using a CNN-LSTM architecture achieved 80% accuracy in analyzing comments on videos. For image captioning, we employed a feature extractor with a CNN layer followed by an LSTM model, achieving a BLEU-1 score of 0.53. Our platform empowers creators by simplifying complex tasks and offering deeper audience engagement insights, making it a powerful tool in the evolving digital content creation.
