الصفحة 33
الصفحة 33
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Cachexia and Wasting : A Modern Approach

Aim of the volume is to provide the best available evidence on the pathogenesis, clinical features and therapeutic approach of cachexia, and to facilitate the understanding of the complex yet unequivocal clinical role of this syndrome, that truly represents a disease, or, better still, a disease within other different diseases.

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C++ mit Visual Studio 2019 : C++17 für Studierende und erfahrene Programmierer

C++ hat sich in den letzten Jahren rasant entwickelt: C++11, C++14, C++17 und C++20 haben viele Verbesserungen und neue Möglichkeiten gebracht. Vieles, was vor 10 Jahren noch gut und empfehlenswert war, kann heute besser und sicherer gemacht werden. Dieses Buch stellt C++ mit Visual Studio 2019 auf dem Stand von Mai 2020 umfassend dar. Das ist nicht nur der Umfang von C++17, sondern auch schon ein Teil von C++20.

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Building ASIPs : The Mescal Methodology

A number of system designers use ASIP's rather than ASIC's to implement their system solutions. This book gives a comprehensive methodology for the design of these application-specific instruction processors (ASIPs). It includes demonstrations of applications of the methodologies using the Tipi research framework.

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Buccal patches of salbutamol

The Potential of alternative routes of application compared to the traditional oral route is constantly growing. Especially in transmucosal applications for the oral cavity, the oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technology advance in mucoadhesive, sustained drug release, permeability enhancers and drug deliver vectors are increasing the efficient delivery of drug to treat oral and systemic disease...

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Brown and Mulholland’s drug calculations

A realistic practice problems and unique "proof" step in the answer key that allows you to double-check your answers to avoid medication errors. This edition continues to promote critical thinking, clinical judgment, and patient safety with respect to accurate drug dosages. Helpful worksheets, assessment tests, and Clinical Alerts call attention to situations in actual practice that have resulted in drug errors — giving you extensive hands-on practice for the Next Generation NCLEX® and beyond.

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Bridging Educational Leadership, Curriculum Theory and Didaktik : Non-affirmative Theory of Education

This book is open access under a CC BY 4.0 license. This volume argues for the need of a common ground that bridges leadership studies, curriculum theory, and Didaktik. It proposes a non-affirmative education theory and its core concepts along with discursive institutionalism as an analytical tool to bridge these fields. It concludes with implications of its coherent theoretical framing for future empirical research.

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Breast cancer chemosensitivity

In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.

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Breast cancer : Nuclear medicine in diagnosis and therapeutic options

This book provides general information on breast cancer management and considers all new methods of diagnosis and therapy. It focuses on nuclear medicine modalities by comparing their results with other diagnostic and therapeutic approaches.

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Brain Metastases

Brain metastases are the most dreaded complication of systemic cancer, affecting approximately 170,000 people a year, a far greater incidence than primary brain tumors. Advances in modern chemotherapy have led to an improved control of system cancers, often with agents that poorly penetrate the central nervous system, resulting in an increasing incidence of brain metastases. Traditional chemotherapy has had little impact on brain metastases. The main therapeutic option is radiation therapy, and in a small number of patients - surgery. However, refinements in all of these treatments offer some positive outcomes and an increased ability to stratify patients based on certain criteria.

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Botulinum toxin

Offering a step-by-step, practical approach to this commonly performed cosmetic procedure, Procedures in Cosmetic Dermatology: Botulinum Toxin, 5th Edition, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. It covers the science behind these neuromodulators and their usage areas in cosmetic dermatology, as well as the latest treatment options—all abundantly illustrated and evidence based. A substantial video library demonstrating injection techniques helps you successfully incorporate the latest procedures into your practice.

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Botanical drug products : Recent developments and market trends

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process.

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Bone Resorption

Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgenic mouse models to human pathology. Another chapter treats diseases of osteoclast function. Because osteoporosis may be considered a disease in which the bone resorption rate exceeds formation, a separate chapter deals with current and potential therapeutic approaches to this widespread disease that affects both men and women. Bone metastases and an analysis of the central role of the osteoclast in this condition are treated in the concluding chapter.

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Bone Morphogenetic Proteins : From Local to Systemic Therapeutics

Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs.

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Bone Marrow Derived Progenitors

The ability of stem cells to acquire different desired phenotypes has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. Each chapter has been written by an accomplished expert in the field, making this a hugely valuable resource for anyone looking for an up-to-the-minute assessment of current practice in adult bone marrow-derived cell therapy.

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BNF for Children 2022-2023

BNF for Children is the first choice for concise medicines information for children. Trusted by healthcare professionals across the world to support confident decision-making at the point of care. provides you with: Up-to-date information on prescribing, dispensing, and administering medicines Authoritative, independent guidance on best practice enabling you to select safe and effective medicines Information you know you can trust for quality, reliability, and independence

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BNF 84 (British National Formulary)

The British National Formulary (BNF) is the first choice for concise medicines information. Trusted by health professionals across the world to support confident decision-making at the point of care.

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BNF 83 : March 2022

The first choice for concise medicines information. Trusted by healthcare professionals across the world to support confident decision-making at the point of care. The new edition (BNF 83) provides up-to-date guidance on prescribing, dispensing, and administering medicines, plus legal and professional guidelines.

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Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics

In this newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, William B. White, MD, and a panel of highly distinguished clinicians give a critical review of every aspect of the evaluation of high blood pressure. This includes home and ambulatory blood pressure monitoring, the relationship between whole-day blood pressure and the cardiovascular disease process, and the effects of antihypertensive therapies on these blood pressure parameters. World-class contributors describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders and demonstrate that ambulatory blood pressure values are independent predictors of cardiovascular morbidity and mortality.

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Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects

Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.

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Biosimilars : Regulatory, clinical, and biopharmaceutical development

Provides a comprehensive overview of the biosimilar regulatory framework, the development process and clinical aspects for development of biosimilars. The development path of a biosimilar is just as unique as a development path of a new drug, tailored by the mechanism of action, the quality of the molecule, published information on the reference product, the current competitive environment, the target market and regulatory guidance, and most importantly, the emerging totality of evidence for the proposed biosimilar during development.

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