الصفحة 31
الصفحة 31
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Alpha-1 antitrypsin : Methods and protocols

Provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Allelopathy : A Physiological Process with Ecological Implications

This book provides the reader relevant information about actual knowledge about the process of allelopathy, covering all aspects from the molecular to the ecological level. Special relevance is given to the physiological and ecophysiological aspects of allelopathy. Several ecosystems are studied and methodological considerations are taken into account in several different chapters. The book has been written to be useful both for Ph.D. students and for senior researchers, so the chapters include all necessary information to be read by beginners, but they also include a lot of useful information and discussion for the initiated.

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Alkaliphiles : Genetic properties and applications of enzymes

The pioneering work of Dr. Koki Horikoshi on the discovery, research and applications of alkaliphilic bacteria are described here in their entirety. The isolation, distribution and taxonomy of alkaliphilic microorganisms as well as their cell structure and physiology are discussed for a basic understanding of these entities. The molecular biology and genome sequencing of some alkaliphilic bacterial strains are also presented. Part II of the volume focuses on enzymes of alkaliphiles and their applications. These include alkaline proteases, starch-degrading enzymes and numerous others. Some of these enzymes are currently in wide commercial use as laundry detergent additives and in wastewater treatment. Alkaliphiles are a relatively recent field of research that will no doubt provide avenues to a wide range of further discoveries and applications for a new generation of workers in bioscience and technology.

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Algorithms in Bioinformatics ; Vol. 3692 ; 5th international workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005, Proceedings

this book present the proceedings of the 5th Workshop on Algorithmsin Bioinformatics (WABI 2005) which took place in Spain, 2005. The Workshop on Algorithms in Bioinformatics highlights research workspecifically developed to address algorithmic problems in biosequence analysis. The emphasis is therefore on statistical and probabilistic algorithms that addressimportant problems in the field of molecular and structural biology. the workshop aims to present recent research results, includingsignificant work in progress, and to identify and explore directions of futureresearch.Original research papers (including significant work in progress) or state-of-the-art surveys were solicited on all aspects of algorithms in bioinformatics,including, but not limited to: exact and approximate algorithms for genomics,genetics, sequence analysis, gene and signal recognition, alignment, molecularevolution, phylogenetics, structure determination or prediction, gene expressionand gene networks, proteomics, functional genomics, and drug design.

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Algorithmic Aspects of Bioinformatics

Advances in bioinformatics and systems biology require improved computational methods for analyzing data, while progress in molecular biology is in turn influencing the development of computer science methods. This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. This book describes topics in detail and presents formal models in a mathematically precise, yet intuitive manner, with many figures and chapter summaries, detailed derivations, and examples. It is well suited as an introduction into the field of bioinformatics, and will benefit students and lecturers in bioinformatics and algorithmics, while also offering practitioners an update on current research topics.

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AI in drug discovery

Constitutes the refereed proceedings of the First international workshop on ai in Drug Discovery, AIDD 2024, held as a part of the 33rd International Conference on Artificial Neural Networks, ICANN 2024, in Lugano, Switzerland, on September 19, 2024. These papers focus on various aspects of the rapidly evolving field of Artificial Intelligence (AI)-driven drug discovery in chemistry, including Big Data and advanced Machine Learning, eXplainable AI (XAI), Chemoinformatics, Use of deep learning to predict molecular properties, Modeling and prediction of chemical reaction data and Generative models.

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Agrobacterium : From Biology to Biotechnology

Agrobacterium’ is a comprehensive book on Agrobacterium research, including its history, application, basic biology discoveries, and effects on human society. Although the book largely focuses on providing a detailed review of virtually all molecular events of the genetic transformation process, it also provides coverage of ethical and legal issues relevant to the use of Agrobacterium as a "genetic transformation machine". The result is an all-inclusive text which readers—including scientists and students involved in plant genetic engineering—will find useful as a reference source for all major aspects of the Agrobacterium-mediated genetic transformation of plant and non-plant organisms.

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Aging and the Heart : A Post-Genomic View

In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken.

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Aging and Senescence

Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. Although recent developments in molecular biology are far from understanding the biological basis of aging, research suggests that targeting the aging process itself could ameliorate many age-related pathologies.

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Advances in wheat genetics : From genome to field : Proceedings of the 12th International wheat genetics symposium

Provides a comprehensive review of the forefront of wheat research, across various important topics such as germplasm and genetic diversity, cytogenetics and allopolyploid evolution, genome sequencing, structural and functional genomics, gene function and molecular biology, biotic stress, abiotic stress, grain quality, and classical and molecular breeding. Following an introduction, 9 parts of the book are dedicated to each of these topics. A final, 11th part entitled “Toward Sustainable Wheat Production” contains 7 excellent papers that were presented in the 12th IWGS Special Session supported by the OECD.

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Advances in plant and animal boron nutrition ; Proceedings of the 3rd International symposium on all aspects of plant and animal boron nutrition

Reviews all aspects of boron research in recent years and is based on the Third International Symposium on all Aspects of Plant and Animal Boron Nutrition which was held in Wuhan, P.R. China. The following issues are discussed: Boron sorption mechanisms in soils / Deficiency and toxicity of boron / Boron fertilizer application / Basic research on the physiology and molecular biology of plant boron nutrition / The nutritional function of boron in animals and humans

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Advances in natural computation ; Vol. 3610 ; 1st International conference, ICNC 2005, Changsha, China, August 27-29, 2005, Proceedings, Part I

Featured the most up-to-date research results in computational algorithms inspired from nature, including biological, ecological, andphysical systems. It is an exciting and emerging interdisciplinary area in which a wide range of techniques and methods are being studied for dealing with large, complex, and dynamic problems. The joint conferences also promoted cross-fertilization over these exciting and yet closely-related areas, which had a sig-nificant impact on the advancement of these important technologies. Specificareas included neural computation, quantum computation, evolutionary com-putation, DNA computation, chemical computation, information processing incells and tissues, molecular computation, computation with words, fuzzy com-putation, granular computation, artificial life, swarm intelligence, ants colonies

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Advances in Molecular Oncology

Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.

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Advances in Molecular Breeding Toward Drought and Salt Tolerant Crops

Advances in Molecular Breeding toward Drought and Salt Tolerant Crops seeks to integrate the most recent findings about key biological determinants of plant stress tolerance with modern crop improvement strategies. This volume is unique because is provides exceptionally wide coverage of current knowledge and expertise being applied in drought and salt tolerance research, spanning the scientific hierarchy from physiology, biochemistry, development, and genetics, to the newest technologies being used to manipulate drought and salinity associated traits for germplasm improvement. This book will be an invaluable reference for educators and researchers in agronomy and horticulture, crop breeding, molecular genetics, and biotechnology.

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Advances in bioinformatics and computational biology ; 2nd Brazilian symposium on bioinformatics, BSB 2007, Angra dos Reis, Brazil, August 29-31, 2007, Proceedings

This book address a broad range of current topics in computationl biology and bioinformatics featuring original research in computer science, mathematics and statistics as well as in molecular biology, biochemistry, genetics, medicine, microbiology and other life sciences.

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Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives

Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.

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Advanced Techniques in Soil Microbiology

"Advanced Techniques in Soil Microbiology" presents a wide range of biotechnological methods for application in soil microbiology analysis. These include all essential methods involving molecular biology, immunology, microbiology, and structural biology, such as transcriptome analysis, RNAi technology, molecular matchmaking, RAPD, T-RFLP and FT/MS. The techniques and procedures have been selected with the aim of offering practical guides for immediate use in the laboratory. The systems investigated range from individual molecules and cells to entire eukaryotic organisms, with a focus on bacteria, fungi, mycorrhiza, and higher plants. This volume of state-of-the-art, practice oriented methods will be of great use both to the first-timer and to the experienced scientist.

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Advanced computer simulation approaches for soft matter sciences I

Soft matter science is nowadays an acronym for an increasingly important class of materials, which ranges from polymers, liquid crystals, colloids up to complex macromolecular assemblies, covering sizes from the nanoscale up the microscale. Computer simulations have proven as an indispensable, if not the most powerful, tool to understand properties of these materials and link theoretical models to experiments. In this first volume of a small series recognized leaders of the field review advanced topics and provide critical insight into the state-of-the-art methods and scientific questions of this lively domain of soft condensed matter research.

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Adult stem cells : Methods and protocols

Expands on the previous edition with updated chapters covering a broader range of tissues and techniques pertaining to stem cell technologies. The chapters also cover topics such as the generation of iPSC-derived cells unique to the individual human genome addressing the possibility of more personalized clinical applications to an individual with a specific degenerative disease; and the use of nanoparticles such as 3D scaffolds and biomaterials as a means of improving stem cell viability after transplantation in the host tissue. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Adsorption and Diffusion

Molecular Sieves - Science and Technology covers, in a comprehensive manner, the science and technology of zeolites and all related microporous and mesoporous materials. Authored by renowned experts, the contributions to this handbook-like series are grouped together topically in such a way that each volume deals with a specific sub-field. Volume 7 is treating fundamentals and analyses of adsorption and diffusion in zeolites including single-file diffusion, i.e. phenomena of basic importance, especially with respect to separation processes and catalysis. Various methods of measuring adsorption and diffusion are described and discussed, i.e. techniques such as chromatographic, gravimetric and barometric uptake and desorption, nuclear magnetic resonance, infrared spectroscopy, interference microscopy, neutron scattering, frequency response as well as proton profiling.

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