NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders : from Genes to Therapeutics
The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.
Novel Trends in Brain Science : Brain Imaging, Learning and Memory, Stress and Fear, and Pain
With the development of neural science, knowledge of the molecules and neurons that comprise the brain has increased exponentially in the past two decades. In Novel Trends in Brain Science, leading neuroscientists from Japan and Taiwan describe the latest and most relevant research in brain science, including state-of-the-art brain-imaging technologies such as fMRI, MR-DTI, TMS, and MEG, and also discuss learning, memory, emotions, and pain. With a wide range of contributors, the book presents valuable insights into functional neuroimaging, white matter tractography, synaptic plasticity, emoti.
Novel NMR and EPR Techniques
This book delivers a survey of recent research in the fields of condensed matter physics and chemistry based on novel NMR and ESR techniques. Applications include quantum computing, metal nanoparticles, low dimensional magnets, fullerenes as atomic cages, superconductors, porous media, and laser assisted studies. The book is dedicated to Professor Robert Blinc, on the occasion of his seventieth birthday, in appreciation of his remarkable scientific accomplishments in the NMR of condensed matter.
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Novel Biotechnologies for Biocontrol Agent Enhancement and Management
This multidisciplinary group, having backgrounds in the diff- ent aspects of biotechnologies (transgenic enhancement, molecular biology, formulation, genetics, risk assessment, new technology, biochemistry, and physiology), presented highly advanced lectures during the 10-day-ASI, in order to allow students to improve their capability to enhance and manage - ological control agents. This approach will allow ASI attendees to bring new ideas, new approaches, or new methodologies coming from different ?elds of application to their own ?eld of expertise.
Notes on Set Theory
This is introduction to axiomatic set theory, viewed both as a foundation of mathematics and as a branch of mathematics with its own subject matter, basic results, open problems.
Notes on Coxeter Transformations and the McKay Correspondence
One of the beautiful results in the representation theory of the finite groups is McKay's theorem on a correspondence between representations of the binary polyhedral group of SU(2) and vertices of an extended simply-laced Dynkin diagram. The Coxeter transformation is the main tool in the proof of the McKay correspondence, and is closely interrelated with the Cartan matrix and Poincaré series. The Coxeter functors constructed by Bernstein, Gelfand and Ponomarev plays a distinguished role in the representation theory of quivers.
Nostalgia and Hope : Intersections between Politics of Culture, Welfare, and Migration in Europe
This book shows how the politics of migration affect community building in the 21st century, drawing on both retrogressive and progressive forms of mobilization. It elaborates theoretically and shows empirically how the two master frames of nostalgia and hope are used in local, national and transnational settings, in and outside conventional forms of doing politics.
Norwegian Shipping in the 20th Century : Norway's Successful Navigation of the World's Most Global Industry
This open access book discusses how Norwegian shipping companies played a crucial role in global shipping markets in the 20th century, at times transporting more than ten per cent of world seaborne trade. Chapters explore how Norway managed to remain competitive, despite being a high labour-cost country in an industry with global competition. Among the features that are emphasised are market developments, business strategies and political decisions The Norwegian experience was shaped by the main breaking points in 20th century world history, such as the two world wars, and by long-term trends, such as globalization and liberalization. The shipping companies introduced technological and organizational innovations to build or maintain a competitive advantage in a rapidly changing world. The growing importance of offshore petroleum exploration in the North Sea from the 1970s was both a threat and an opportunity to the shipping companies. By adapting both business strategies and the political regime to the new circumstances, the Norwegian shipping sector managed to maintain a leading position internationally.
Non-viral Gene Therapy: Gene Design and Delivery
The development of gene medicine based on the concept of molecular therapy has opened new medical horizons. Among the many techniques in gene medicine, gene design and delivery are especially significant in clinical applications. This book presents state-of-the-art information on non-viral gene-delivery techniques, covering a broad spectrum of disciplines that include chemistry, molecular biology, cell biology, and pharmacokinetics
Nonstandard Analysis
The book is an introduction with emphasis on those more advanced applications in analysis which are hardly accessible by other methods. Examples of such topics are a deeper analysis of certain functionals like Hahn-Banach limits or of finitely additive measures: From the viewpoint of classical analysis these are strange objects whose mere existence is even hard to prove. From the viewpoint of nonstandard analysis, these are rather 'explicit' objects.
Nonsmooth Mechanics and Analysis : Theoretical and Numerical Advances
Nonsmooth mechanics concerns mechanical situations with possible nondifferentiable relationships, eventually discontinuous, as unilateral contact, dry friction, collisions, plasticity, damage, and phase transition. The basis of the approach consists in dealing with such problems without resorting to any regularization process. Indeed, the nonsmoothness is due to simplified mechanical modeling; a more sophisticated model would require too large a number of variables, and sometimes the mechanical information is not available via experimental investigations. Therefore, the mathematical formulation becomes nonsmooth; regularizing would only be a trick of arithmetic without any physical justification. Nonsmooth analysis was developed, especially in Montpellier, to provide specific theoretical and numerical tools to deal with nonsmoothness. It is important not only in mechanics but also in physics, robotics, and economics.
Nonlinear Waves : Classical and Quantum Aspects
Leading scientists discuss the most recent physical and experimental results in the physics of Bose-Einstein condensate theory, the theory of nonlinear lattices (including quantum and nonlinear lattices), and nonlinear optics and photonics. Classical and quantum aspects of the dynamics of nonlinear waves are considered. The contributions focus on the Gross-Pitaevskii equation and on the quantum nonlinear Schrödinger equation. Recent experimental results on atomic condensates and hydrogen bonded systems are reviewed. Particular attention is given to nonlinear matter waves in periodic potential.
Nonlinear Smoothing and Multiresolution Analysis
This monograph presents a new theory for analysis, comparison and design of nonlinear smoothers, linking to established practices. Although a part of mathematical morphology, the special properties yield many simple, powerful and illuminating results leading to a novel nonlinear multiresolution analysis with pulses that may be as natural to vision as wavelet analysis is to acoustics. Similar to median transforms, they have the advantages of a supporting theory, computational simplicity, remarkable consistency, full trend preservation, and a Parceval-type identity.
Nonlinear Fokker-Planck Equations : Fundamentals and Applications
Providing an introduction to the theory of nonlinear Fokker-Planck equations, this book discusses fundamental properties of transient and stationary solutions, emphasizing the stability analysis of stationary solutions by means of self-consistency equations, linear stability analysis, and Lyapunov's direct method. Also treated are Langevin equations and correlation functions. Nonlinear Fokker-Planck Equations addresses various phenomena such as phase transitions, multistability of systems, synchronization, anomalous diffusion, cut-off solutions, travelling-wave solutions and the emergence of power law solutions. A nonlinear Fokker-Planck perspective to quantum statistics, generalized thermodynamics, and linear nonequilibrium thermodynamics is given. Theoretical concepts are illustrated where possible by simple examples. The book also reviews several applications in the fields of condensed matter physics, the physics of porous media and liquid crystals, accelerator physics, neurophysics, social sciences, population dynamics, and computational physics.
Nonlinear Dynamics of Structures Under Extreme Transient Loads
Covers model building for different engineering structures and provides detailed presentations of extreme loading conditions. A number of illustrations are given quantifying; a plane crash or explosion induced impact loading, the effects of strong earthquake motion, and the impact and long-duration effects of strong stormy winds—along with a relevant framework for using modern computational tools. The book considers the levels of reserve in existing structures, and ways of reducing the negative impact of high-risk situations by employing sounder design procedures.
Non-Linear Dynamics Near and Far from Equilibrium
This text gives a detailed account of various techniques that are used in the study of dynamics of continuous systems, near as well as far from equilibrium. The analytic methods covered include diagrammatic perturbation theory, various forms of the renormalization group and self-consistent mode coupling.
Non-Linear Dynamics and Fundamental Interactions
This volume contains the papers presented at the NATO Advanced Research Institute on "Non-Linear Dynamics and Fundamental Interactions" held in Tashkent, Uzbekistan, from Oct.10-16,2004. The main objective of the Workshop was to bring together people working in areas of Fundamental physics relating to Quantum Field Theory, Finite Temperature Field theory and their applications to problems in particle physics, phase transitions and overlap regions with the areas of Quantum Chaos. The other important area is related to aspects of Non-Linear Dynamics which has been considered with the topic of chaology. The applications of such techniques are to mesoscopic systems, nanostructures, quantum information, particle physics and cosmology. All this forms a very rich area to review critically and then find aspects that still need careful consideration with possible new developments to find appropriate solutions.
Nonlinear Analysis and Synthesis Techniques for Aircraft Control
Given the continuous increase in the complexity of aircraft control laws, and the corresponding - crease in the demands on their performance and reliability, industrial control law designers are highly motivated to explore the applicability of new and more powerful methods for design and analysis. The successful application of fully nonlinear control techniques to aircraft control problems o?ers the prospect of improvements in several di?erent areas. Firstly, there is the possibility of - proving design and analysis criteria to more fully re?ect the nonlinear nature of the dynamics of the aircraft. Secondly, the time and e?ort required on the part of designers to meet demanding speci?cations on aircraft performance and h- dling could be reduced. Thirdly, nonlinear analysis techniques could potentially reduce the time and resources required to clear ?ight control laws, and help to bridge the gap between design, analysis and ?nal ?ight clearance.
Non-Equilibrium Phase Transitions ; Vol. I : Absorbing Phase Transitions
This book describes two main classes of non-equilibrium phase-transitions: (a) static and dynamics of transitions into an absorbing state, and (b) dynamical scaling in far-from-equilibrium relaxation behaviour and ageing. The first volume begins with an introductory chapter which recalls the main concepts of phase-transitions, set for the convenience of the reader in an equilibrium context. The extension to non-equilibrium systems is made by using directed percolation as the main paradigm of absorbing phase transitions and in view of the richness of the known results an entire chapter is devoted to it, including a discussion of recent experimental results. Scaling theories and a large set of both numerical and analytical methods for the study of non-equilibrium phase transitions are thoroughly discussed.



















