الصفحة 3
الصفحة 3
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Novel Carrier Systems for Targeted and Controlled Drug Delivery
Presents novel carrier systems for the targeted and controlled drug delivery for the treatment of various diseases which are difficult to be treated with conventional drug delivery systems like cancer, autoimmune disorders, and emerging infectious diseases. It also reviews the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The book also explores the potential applications of the parenteral route of administration for the delivery of active pharmaceutical substances with a narrow therapeutic index and poor bioavailability. Further, the book presents common routes of administration for the systemic delivery of peptides and proteins. It also examines the applications of various implantable systems in drug delivery. The book also covers the important colloidal drug delivery systems, including liposomes and niosomes and solid lipid nanoparticles, and nanostructured lipid carriers.
Novel Biotechnologies for Biocontrol Agent Enhancement and Management
This multidisciplinary group, having backgrounds in the diff- ent aspects of biotechnologies (transgenic enhancement, molecular biology, formulation, genetics, risk assessment, new technology, biochemistry, and physiology), presented highly advanced lectures during the 10-day-ASI, in order to allow students to improve their capability to enhance and manage - ological control agents. This approach will allow ASI attendees to bring new ideas, new approaches, or new methodologies coming from different ?elds of application to their own ?eld of expertise.
Northeast Asia : Ripe for Integration?
Can regional mechanisms better institutionalize the increasing complexity of economic and security ties among the countries in Northeast Asia? As the international state system undergoes dramatic changes in both security and economic relations in the wake of the end of the Cold War, the Asian financial crisis, and the attack of 9/11, this question is now at the forefront of the minds of both academics and policymakers. Still, little research has been done to integrate the analysis of security and economic analysis of changes in the region within a broader context that will give us theoretically-informed policy insights. Against this backdrop, this book investigates the origins and evolution of Northeast Asia's new institutional architecture in trade, finance, and security from both a theoretical and empirical perspective.
Nonsmooth Variational Problems and their Inequalities : Comparison Principles and Applications
The main purpose of this book is to provide a systematic and unified exposition of comparison principles based on a suitably extended sub-supersolution method. This method is an effective and flexible technique to obtain existence and comparison results of solutions. Also, it can be employed for the investigation of various qualitative properties, such as location, multiplicity and extremality of solutions. In the treatment of the problems under consideration a wide range of methods and techniques from nonlinear and nonsmooth analysis is applied, a brief outline of which has been provided in a preliminary chapter in order to make the book self-contained.
Nonsmooth Mechanics and Analysis : Theoretical and Numerical Advances
Nonsmooth mechanics concerns mechanical situations with possible nondifferentiable relationships, eventually discontinuous, as unilateral contact, dry friction, collisions, plasticity, damage, and phase transition. The basis of the approach consists in dealing with such problems without resorting to any regularization process. Indeed, the nonsmoothness is due to simplified mechanical modeling; a more sophisticated model would require too large a number of variables, and sometimes the mechanical information is not available via experimental investigations. Therefore, the mathematical formulation becomes nonsmooth; regularizing would only be a trick of arithmetic without any physical justification. Nonsmooth analysis was developed, especially in Montpellier, to provide specific theoretical and numerical tools to deal with nonsmoothness. It is important not only in mechanics but also in physics, robotics, and economics.
Nonsmooth Analysis
The book treats various concepts of generalized derivatives and subdifferentials in normed spaces, their geometric counterparts (tangent and normal cones) and their application to optimization problems. It starts with the subdifferential of convex analysis, passes to corresponding concepts for locally Lipschitz continuous functions and finally presents subdifferentials for general lower semicontinuous functions. All basic tools are presented where they are needed; this concerns separation theorems, variational and extremal principles as well as relevant parts of multifunction theory. The presentation is rigorous, with detailed proofs. Each chapter ends with bibliographic notes and exercises.
Nonparametric Monte Carlo Tests and Their Applications
A fundamental issue in statistical analysis is testing the fit of a particular probability model to a set of observed data. Monte Carlo approximation to the null distribution of the test provides a convenient and powerful means of testing model fit. Nonparametric Monte Carlo Tests and Their Applications proposes a new Monte Carlo-based methodology to construct this type of approximation Every chapter of the book includes algorithms, simulations, and theoretical deductions. The prerequisites for a full appreciation of the book are a modest knowledge of mathematical statistics and limit theorems in probability,empirical process theory.
Nonparametric Bayesian Learning for Collaborative Robot Multimodal Introspection
This book focuses on robot introspection, which has a direct impact on physical human–robot interaction and long-term autonomy, and which can benefit from autonomous anomaly monitoring and diagnosis, as well as anomaly recovery strategies.
Nonlinear Time Series Analysis in the Geosciences : Applications in Climatology, Geodynamics and Solar-Terrestrial Physics
This book presents recent developments in nonlinear time series which have been motivated by present day problems in geosciences. Modern methods of spatio-temporal data analysis, time-frequency analysis, dimension analysis, nonlinear correlation and synchronization analysis and other nonlinear concepts are used to study emerging questions in climatology, geophysics, solar-terrestrial physics and related scientific disciplines. This volume collects contributions of some of the world's leading experts in geoscientific time series analysis.
Nonlinear Smoothing and Multiresolution Analysis
This monograph presents a new theory for analysis, comparison and design of nonlinear smoothers, linking to established practices. Although a part of mathematical morphology, the special properties yield many simple, powerful and illuminating results leading to a novel nonlinear multiresolution analysis with pulses that may be as natural to vision as wavelet analysis is to acoustics. Similar to median transforms, they have the advantages of a supporting theory, computational simplicity, remarkable consistency, full trend preservation, and a Parceval-type identity.
Nonlinear Partial Differential Equations with Applications
This book primarily concerns quasilinear and semilinear elliptic and parabolic partial differential equations, inequalities, and systems. It balances the abstract functional-analysis approach based on nonlinear monotone, pseudomonotone, weakly continuous, or accretive mappings with concrete partial differential equations in their weak (or more general) formulation. Methods of Galerkin or of Rothe are exposed in a large generality. Other methods include various direct methods, regularization, or fixed points. The exposition leads general theory as fast as possible towards the analysis of concrete equations, which have specific applications in continuum (thermo-) mechanics of solids and fluids, electrically (semi-) conductive media, modelling of biological systems, or in mechanical engineering. Selected parts are rather an introduction into the subject while some others form an advanced textbook. The intended audience is graduate and PhD students and researchers in the theory of partial differential equations or in mathematical modelling of distributed parameter systems.
Nonlinear Homogenization and its Applications to Composites, Polycrystals and Smart Materials ; Proceedings of the NATO Advanced Research Workshop, held in Warsaw, Poland, 23-26 June 2003
Although several books and conference proceedings have already appeared dealing with either the mathematical aspects or applications of homogenization theory, there seems to be no comprehensive volume dealing with both aspects. The present volume is meant to fill this gap, at least partially, and deals with recent developments in nonlinear homogenization emphasizing applications of current interest. It contains thirteen key lectures presented at the NATO Advanced Workshop on Nonlinear Homogenization and Its Applications to Composites, Polycrystals and Smart Materials. The list of thirty one contributed papers is also appended.
Nonlinear Fokker-Planck Equations : Fundamentals and Applications
Providing an introduction to the theory of nonlinear Fokker-Planck equations, this book discusses fundamental properties of transient and stationary solutions, emphasizing the stability analysis of stationary solutions by means of self-consistency equations, linear stability analysis, and Lyapunov's direct method. Also treated are Langevin equations and correlation functions. Nonlinear Fokker-Planck Equations addresses various phenomena such as phase transitions, multistability of systems, synchronization, anomalous diffusion, cut-off solutions, travelling-wave solutions and the emergence of power law solutions. A nonlinear Fokker-Planck perspective to quantum statistics, generalized thermodynamics, and linear nonequilibrium thermodynamics is given. Theoretical concepts are illustrated where possible by simple examples. The book also reviews several applications in the fields of condensed matter physics, the physics of porous media and liquid crystals, accelerator physics, neurophysics, social sciences, population dynamics, and computational physics.
Nonlinear Finite Element Methods
Finite element methods have become ever more important to engineers as tools for design and optimization, now even for solving non-linear technological problems. However, several aspects must be considered for finite-element simulations which are specific for non-linear problems: These problems require the knowledge and the understanding of theoretical foundations and their finite-element discretization as well as algorithms for solving the non-linear equations. This book provides the reader with the required knowledge covering the complete field of finite element analyses in solid mechanics.
Nonlinear finite element analysis of composite and reinforced concrete beams
Nonlinear Finite Element Analysis of Composite and Reinforced Concrete Beams presents advanced methods and techniques for the analysis of composite and FRP reinforced concrete beams. The title introduces detailed numerical modeling methods and the modeling of the structural behavior of composite beams, including critical interfacial bond-slip behavior. It covers a new family of composite beam elements developed by the authors. Other sections cover nonlinear finite element analysis procedures and the numerical modeling techniques used in commercial finite element software that will be of particular interest to engineers and researchers executing numerical simulations.
Nonlinear Dynamics in Geosciences
Nonlinear Dynamics in Geosciences is comprised of the proceedings of "20 Years of Nonlinear Dynamics in Geosciences", held June 11-16, 2006 in Rhodes, Greece as part of the Aegean Conferences. The volume brings together the most up-to-date research from the atmospheric sciences, hydrology, geology, and other areas of geosciences, and discusses the advances made in the last two decades and the future directions of nonlinear dynamics. Topics covered include predictability, ensemble prediction, nonlinear prediction, nonlinear time series analysis, low-dimensional chaos, nonlinear modeling, fractals and multifractals, bifurcation, complex networks, self-organized criticality, extreme events, and other aspects of nonlinear science.
Nonlinear dynamics in complex systems via fractals and fractional calculus
Current advances in the knowledge of nonlinear dynamical networks, systems and processes, as well as their unified repercussions, allow us to include some typical complex natural phenomena, from the nanoscale to an extra-galactic scale, in an unitarian comprehensive manner. In other words, the physical, biological and financial data, as well as technological ones (mechanical or electronic devices), of complex systems available today can be managed by the same unique conceptual approach, both analytically and through a computer simulation, using effective nonlinear dynamics procedures. This volume collected some important advances in the fields of fractal curves, fractal analysis and fractional calculus, as well as new solutions of fractal differential equations.
Nonlinear Dimensionality Reduction
This book describes existing and advanced methods to reduce the dimensionality of numerical databases. For each method, the description starts from intuitive ideas, develops the necessary mathematical details, and ends by outlining the algorithmic implementation. Methods are compared with each other with the help of different illustrative examples. The purpose of the book is to summarize clear facts and ideas about well-known methods as well as recent developments in the topic of nonlinear dimensionality reduction. With this goal in mind, methods are all described from a unifying point of view, in order to highlight their respective strengths and shortcomings.
Nonequilibrium Phenomena in Plasmas
This book presents studies of complexity in the context of nonequilibrium phenomena using theory, modeling, simulations, and experiments, both in the laboratory and in nature.
