الصفحة 27
الصفحة 27
DNA Binders and Related Subjects
advances in technology and the application of new methods to outstanding problems have played a major part in the development of ideas about drug-nucleic acid recognition. The field has undergone an explosive diversification as wider and wider problems became accessible to study using the new ideas and techniques. This volume reflects that diversification by offering accounts of selected areas that illustrate recent advances in the study of ligand–nucleic acid binding over disparate areas of the subject. There are chapters dealing specifically with the invention and application of new methodology, and a particularly thoughtful essay on the interpretation of X-ray diffraction data which may not be as straightforward as is often imagined. Other chapters illustrate the diversity and complexity of drug-DNA binding from several perspectives, referring to particular groups of related compounds or the potential attractions of the less-preferred DNA major groove as a target for nucleotide sequence recognition by ligands.
DNA- and RNA-Based Computing Systems
DNA- and RNA-Based Computing Systems delivers an authoritative overview of DNA- and RNA-based biocomputing systems that touches on cutting-edge advancements in computer science, biotechnology, nanotechnology, and materials science.
DNA and RNA origami : methods and protocols
Detials diverse methodological approaches on the assembly and applications of DNA origami assemblies. Chapters guide readers through different synthetic and computational methods, isolation and structural characterization of 2D and 3D DNA origami nanoarchitectures, nanophotonics, drug delivery, biophysics, and synthetic biology.Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Discoveries in Photosynthesis
Conceived of as a way of summarizing the history of research advances in photosynthesis as of millennium 2000, the book evolved into a majestic and encyclopedic saga involving all of the basic sciences. This book is meant not only for the researchers and graduate students, but also for advanced undergraduates in Plant Biology, Microbiology, Cell Biology, Biochemistry, Biophysics and History of Science.
Directory of microbicides for the protection of materials : A handbook
This edition is divided into two parts. In Part One 23 contributions of worldwide selected experts present extensively diversified information about: -Microbicides with regard to the relationship between chemical structure and mode of action and activity, -Research and development in consideration of registration procedures,Legislative aspects,The use of microbicides in the major application areas (18) which are described in detail.The Microbicide Data is organized into 21 substance classes (e.g. alcohols, aldehydes, acids, amides, etc.) and collected in Part Two.
Directed Metallation
a new chelation-assisted methodology has been developed not only for controlling regio- and stereoselectivity of reactions, but also for accelerating reactions. In particular, chelation-methodology has been utilized as a new activation method, in which a carbon-metal bond is generated directly from a C-H bond; a reaction rarely achieved using conventional methods. A wide variety of catalytic functionalization reactions of C-H bonds by the utilization of a chelation, have been developed recently and are comprehensively discussed in this book by leading experts. In addition, new approaches to directed hydrometalation and directed carbometalation as a key step are also discussed. A unique stereo- and regioselective hydroformylation has been developed through the utilization of directed hydrometalation.
Dioxygen Binding and Sensing Proteins : A Tribute to Beatrice and Jonathan Wittenberg
Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments.This book is dedicated to Jonathan’s and Bea’s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.
Dilute III-V Nitride Semiconductors and Material Systems : Physics and Technology
A major current challenge for semiconductor devices is to develop materials for the next generation of optical communication systems and solar power conversion applications. Recently, extensive research has revealed that an introduction of only a few percentages of nitrogen into III-V semiconductor lattice leads to a dramatic reduction of the band gap. This discovery has opened the possibility of using these material systems for applications ranging from lasers to solar cells. Physics and Technology of Dilute III-V Nitride Semiconductors & Novel Dilute Nitride Material Systems reviews the current status of research and development in dilute III-V nitrides, with 24 chapters from prominent research groups covering recent progress in growth techniques, experimental characterization of band structure, defects carrier transport, transport properties, dynamic behavior of N atoms, device applications, modeling of device design, novel optoelectronic integrated circuits, and novel nitrogen containing III-V materials.
Digital transformation of the Laboratory : A practical guide to the connected lab
Digital Transformation of the Laboratory: A Practical Guide to the Connected Lab delivers essential and transformative new insights into current and future technologies and strategies for the digitization of laboratories. Thoroughly supported and backed-up with contributions from thought and industry leaders, the book shows scientists in academia and industry how to move from paper to digital in their own labs.
Digital Simulation in Electrochemistry
The book shows how to numerically solve the parabolic partial differential equations (pdes) encountered in electroanalytical chemistry. It does this in a didactic manner, by first introducing the basic equations to be solved and some model systems as text cases, for which solutions exist. Then it treats basic numerical approximation for derivatives and techniques for the numerical solution of ordinary differential equations, from which the more complicated methods for pdes can be derived. The major implicit methods are described in detail, and the handling of homogeneous chemical reactions, including coupled and nonlinear cases, is detailed. More advanced techniques are presented briefly, as well as some commercially available program packages.
Diffusion in Condensed Matter : Methods, Materials, Models
Diffusion as the process of particle transport due to stochastic movement is a phenomenon of crucial relevance for a large variety of processes and materials. This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. Leading experts in the field describe in 23 chapters the different aspects of diffusion, covering microscopic and macroscopic experimental techniques and exemplary results for various classes of solids, liquids and interfaces as well as several theoretical concepts and models. Students and scientists in physics, chemistry, materials science, and biology will benefit from this detailed compilation.
Differential Optical Absorption Spectroscopy : Principles and Applications
This book reviews the basics of atmospheric chemistry, radiation transport, and optical spectroscopy before detailing the principles underlying DOAS. The second part of the book describes the design and application of DOAS instruments as well as the evaluation and interpretation of spectra. The recent expansion of DOAS application to the imaging of trace gas distributions by ground, aircraft, and satellite-based instruments is also covered.
Development of trans-free lipid systems and their use in food products
Encompasses the work of leading researchers discussing, from a scientific and technological perspective, the latest and most innovative approaches to structure edible oils without the use of trans fats. Additionally, the authors discuss practical uses and technical limitations associated with the use of "structured edible oils" in different food systems. Appealing to researchers and professionals working in lipid science, food chemistry and fat metabolism, it fills the gap in the literature for a book in this fast-changing field.
Development of breast cancer therapy and gender
Breast cancer is a disease in which abnormal cells in the breast tissues multiply and form an invasive (or malignant) tumor. Such tumors can invade and damage the tissue around them and spread to other parts of the body through the lymphatic or vascular systems. We will describe in our study several types of breast cancer, since they are classified into two main categories: “invasive” and “non-invasive,” or in situ. While invasive cancer has spread from the breast ducts or glands to other parts of the breast, non-invasive cancer has not spread from the original tissue. Our study will focus on the best tests that examine the breasts which are used to detect and diagnose breast cancer: Physical exam and health history, Clinical breast exam (CBE), Mammogram, Ultrasound exam, MRI (magnetic resonance imaging), Blood chemistry studies and Biopsy. We will include the value of such tests after breast cancer has been diagnosed, to find out if cancer cells have spread within the breast or to other parts of the body.
Detection of Liquid Explosives and Flammable Agents in Connection with Terrorism
The organization of an Advanced Research Workshop with the title “Detection and Disposal of Liquid Explosives and Flammable Agents in Connection with Terrorism” was motivated by international findings about activities in this field of application. This ARW followed a meeting about the “Detection of Disposal Improvised Explosives” (St. Petersburg, 2005). Both items show the logistic problems as one of the lessons, terrorists have to overcome. These problems are connected with the illegal supply and transport of explosives and fuels and as counter-measure the detection of these materials. The invention of liquid explosives goes back to the middle of the 19th century and was used for special purposes in the commercial field of application. Because of the high sensitivity of liquid explosives against mechanical shock, caused by adiabatic compression of air-bobbles producing “hot spots” as origin of initiation the commercial application was not very successful. Because of this high risk, liquid explosives are not used in military or commercial application with some exceptions. In the commercial field explosives as slurries or emulsions consisting of suitable salts (Ammoniumnitrate etc.) and water are used to a large extend because of their high insensitivity. In many cases these slurries or emulsions were unfit for terrorist actions, because of their low sensitivity, large critical diameter and using in confinement. In the military field liquid explosives are used in World War I and II as bomb-fillings.
Detection and Disposal of Improvised Explosives
It including: Methods of detection of Improvised Explosives (IE). Methods of detection of Improvised explosives devices (IED). Disposal and safe handling of ID and IED. The treatment of detection methods may be divided in the following groups: Overview about the different methods; Trace- and vapor detection; Electromagnetic methods; Neutron methods; Laser techniques. Because of different definitions of Improvised Explosives the parti- pants of the workshop agreed after some discussions with the following definition: An Improvised Explosive (IE) can be any chemical compound or mixture capable of an explosive reaction. They are normally easily prepared by a knowledgeable layman under simple conditions. Components of IE are typically inorganic salts containing molecular bound oxygen like nitrates, chlorates or perchlorates etc. or organic compounds with nitro-, nitami- or nitrate-groups or peroxides. Admixtures of military or commercial explosive materials are also used. From the chemical point of view IE can be divided into the following types: Salts containing chemical groups with oxygen (like nitrates, chlorates or perchlorates etc.) in mixtures with combustible substances like carbon-hydrogen compounds.
Detection and analysis of SARS Coronavirus : Advanced biosensors for pandemic viruses and related pathogens
The highly contagious SARS CoV-2 pathogen has challenged health systems around the world as they struggle to detect and monitor the spread of the pathogen. In Detection and Analysis of SARS Coronavirus: Advanced Biosensors for Pandemic Viruses and Related Pathogens expert chemists Chaudhery Mustansar Hussain and Sudheesh K. Shukla deliver a practical analysis of how contactless coronavirus detectors may be developed using existing biosensor technology.
Dental Hard Tissues and Bonding : Interfacial Phenomena and Related Properties
This book comprehensively reviews bonding to enamel, dentin and cementum and analyses relevant adhesion mechanisms. Emphasis is placed on the characterization of material interfaces with dental tissues in situ. The volume also stresses the importance of appropriate experimental protocol design in facilitating clinically-relevant research methods, clarifies the mechanisms of adhesion of polymeric materials to hard dental tissues and furnishes a handy reference for routine clinical procedures in restorative and prosthetic dentistry as well as orthodontics. The book introduces important aspects of the chemistry of dental materials and their adaptation to dental hard tissues. It also analyses interfacial phenomena occurring during application of materials, including mechanical properties, and structural-compositional alterations. The text presents the current instrumental approaches in studying related issues and a summary of the current status of theories concerning bonding to dental tissues.
Dental gold alloys and gold nanoparticles for biomedical applications
Focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with an extremely robust chemical stability in the mouth.
Dendrimer Catalysis
catalytically active dendrimers have emerged as a class of molecular catalysts that has substantially enriched the field of homogeneous (and in part heterogeneous) catalysis. A general survey of transition metal dendrimer catalysts and the way they have developed is followed by in-depth discussions of dendritic transition metal catalysis based on non-covalent catalyst-support interaction and an overview of the rapidly growing field of stereoselective dendrimer catalysis. The development of dendrimer-encapsulated bimetallic nanoparticles has provided the interface with heterogeneous colloid catalysis. As cheaper and readily accessible alternatives to regular dendrimers, hyperbranched polymers are increasingly being used as catalyst platforms. These topics are complemented by a review of metallodendritic exoreptors for the redox recognition of oxo-anions and halides.
