الصفحة 25
الصفحة 25
Baculovirus : Methods and protocols
Provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacteriophage therapy: From lab to clinical practice
Details new and updated experimental approaches for isolating, formulating, and engineering bacteriophage medicinal products. Authored by leading experts and written in the highly successful Methods in Molecular Biology series format, each chapter includes introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and valuable tips for troubleshooting and avoiding known pitfalls.
Bacteriophage therapy : a potential solution for antibiotic resistance crisis
For many years, humans have been fighting with bacteria, in a matter of fact, bacteria have been winning for the last decade, becoming resistant to every weapon we have; The antibiotics. In order to win the fight humans had to think of alternative ways, like viruses. There is a special type of viruses that have been in a war with bacteria for millenniums, Bacteriophages. Bacteriophages (or phages), the most abundant viral entity of the planet. On the basis of their unique characteristics and anti-bacterial property, phages are being the freshly evaluated taxonomically. Phages replicate inside the host either by lytic or lysogenic mode after infecting and using the cellular machinery of a bacterium. Phage became an important agent for combating pathogenic bacteria in clinical treatments and its related research gained momentum. However, due to recent rise of bacterial resistance on antibiotics, applications of phage (phage therapy) become an unavoidable option of research. In this dissertation, the advantage and limitations of Bacteriophages for use in humans will be discussed. Furthermore, this dissertation deals with recent development of its application in the areas of biotechnology.
Bacterial regulatory RNA : Methods and protocols
Details new and updated methods used for studying prokaryotic non-coding RNAs and their protein accomplices. Chapters detail discovery of ncRNAs, characterization of their structure, functions, and their interactomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Bacterial chromatin : Methods and protocols
Brings together new and updated methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in vivo and in vitro approaches, approaches to genome structure modeling, and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Bacterial Biofilms
This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.
Autonomous Robots and Agents
This book deals with the theoretical and methodological aspects of incorporating intelligence in Autonomous Robots and Agents. Challenges faced in the real world to accomplish complex tasks, which require collaborative efforts, and methods to overcome them, are detailed. Several informative articles deal with navigation, localization and mapping of mobile robots, a problem that engineers and researchers are grappling with all the time.This edited volume is targeted to present the latest state-of-the-art methodologies in Robotics. It is a compilation of the extended versions of the very best papers selected from the many that were presented at the 3rd International Conference on Autonomous Robots and Agents (ICARA 2006) which was held at Palmerston North, New Zealand from 11-14 December, 2006. Scientists and engineers who work with mobile robots will find this book very useful and stimulating.
Autonomous intelligent systems : Multi-agents and data mining ; 2nd International workshop, AIS-ADM 2007, St. Petersburg, Russia, June 3-5, 2007, Proceedings
MAS offiers powerful metaphors for information system conceptualization, a range of new techniques, and technologies specifically focused on the design and implementation of lar- scale open distributed intelligent systems. KDD also provides intelligent inf- mation technology with powerful ideas, algorithms, and software means to help cope with the main problem of artificial intelligence, formulated in the we- known question “Where does the knowledge come from?”, thus actually making modern applications intelligent and adaptive. The evident recent trend in both science and industry is to integrate and take advantage of both technologies. The existing experience with combined application of multi-agent technology to design architectures of distributed (- erarchical and peer-to-peer) data mining and KDD systems, as well as the u- lization of data mining and KDD achievements to provide enhanced intelligence of MAS, confirms the fact that both technologies are capable of mutual enri- ment and their integrateduse may result in intelligent information systems with new emergent properties.
Autonomous intelligent systems : Agents and data mining ; International workshop, AIS-ADM 2005
This book constitutes the refereed proceedings of the International Workshop on Autonomous Intelligent Systems: Agents and Data Mining, AIS-ADM 2005, held in St. Petersburg, Russia in June 2005. The 17 revised full papers presented together with 5 invited papers and the abstract of an invited talk were carefully reviewed and selected from 29 submissions. The papers are organized in topical sections on agent-based data mining issues, ontologies and Web mining, and applications and case studies.
Autoimmunity : Methods and protocols
Brings together a comprehensive and up-to-date collection of protocols that reflect the diverse experimental strategies. Chapters detail T-cell, macrophage characterization, neutrophil functional assays, organoid culture methods, spatial transcriptomics, RNA FISH, microRNA profiling, and ribosome profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Assessment of the fate and effects of toxic agents on water resources
Like all limited and vulnerable resources, water has become one of the potential targets of terrorists. Coastal lagoons are especially vulnerable as they are densely populated centers of commerce and/or tourism. This volume addresses the basic scientific concepts that must be integrated by decisionmakers to minimize damages and optimize recovery operations in the aftermath of such an attack. Scientists from many disciplines including water resource management, hydrodynamics, aquatic ecology and social science combine their expertise in an effort to assess and model emergency scenarios for coastal lagoon systems. This case study uses existing numerical models such as-EFCD, WASP and AQUATOX are used to demonstrate how to optimize rapid response and decision-making
Aspirin tablet film coated with famotidine
Focuses on enhancing the gastrointestinal tolerance of aspirin tablets by coating them with famotidine, a histamine-2 receptor antagonist known for its ability to reduce stomach acid production. The project aims to investigate the potential of famotidine coating in mitigating the gastric side effects commonly associated with aspirin usage, such as gastric irritation and ulcers. Through a series of in vitro studies, the project will evaluate the effectiveness of famotidine-coated aspirin tablets in reducing gastric mucosal damage and improving overall gastrointestinal safety.
Artificial neural networks – ICANN 2007 ; 17th International Conference, Porto, Portugal, September 9-13, 2007, Proceedings, Part I
This book contains learning theory, advances in neural network learning methods, ensemble learning, spiking neural networks, advances in neural network architectures neural network technologies, neural dynamics and complex systems, data analysis, estimation, spatial and spatio-temporal learning, evolutionary computing, meta learning, agents learning, complex-valued neural networks, as well as temporal synchronization and nonlinear dynamics in neural networks.
Artificial Intelligence. IJCAI 2019 International Workshops ; Macao, China, August 10–12, 2019, Revised Selected Best Papers
This book presents selected papers of 12 Workshops held in conjunction with the 28th International Joint Conference on Artificial Intelligence, IJCAI 2019, in Macao, China, in August 2019.
Artificial intelligence in the design process : The impact on creativity and team collaboration
Discusses how to include artificial intelligence (AI) systems in the early stages of the design process. Today designers need new tools capable of supporting them in dealing with the increasing project's complexity and empowering their performances and capabilities. AI systems appear to be powerful means to enhance designers' creativity. This assumption was tested in a workshop where sixteen participants collaborated with three AI systems throughout the creative phases of research, sketching, and color selection. Results show that designers can access a broader level of variance and inspiration while reducing the risk of fossilization by triggering lateral thinking through AI-generated data. Therefore, AI could significantly impact the creative phases of the design process if applied consciously. Being AI systems intelligent agents, the book treats the Human-AI collaboration as a collaboration between human agents, proposing a set of guidelines helpful to achieving an efficient partnership with the machine.
Artificial intelligence applications and innovations II; IFIP TC12 and WG12.5 ; 2nd IFIP conference on artificial intelligence applications and innovations (AIAI-2005), Sept. 7-9, 2005, Beijing, China
Artificial Intelligence is one of the oldest and most exciting subfields of computing, covnering such areas as intelligent robotics, intelligent planning and scheduling, model-based reasoning, fault diagnosis, natural language processing, maching translation, knowledge representation and reasoning, knowledge-based systems, knowledge engineering, intelligent agents, machine learning, neural nets, genetic algorithms and knowledge management. The papers in this volume comprise the refereed proceedings of the Second International Conference on Artificial Intelligence Applications and Innovations,held in Beijing, China in 2005.
Artificial intelligence : Methodology, systems, and applications ; 12th International Conference, AIMSA 2006, Varna, Bulgaria, September 12-15, 2006, Proceedings
This book constitutes the refereed proceedings of the 12th International Conference on Artificial Intelligence: Methodology, Systems, and Applications, AIMSA 2006. The 28 revised full papers presented together with the abstracts of 2 invited lectures were carefully reviewed and selected from 81 submissions. The papers are organized in topical sections on agents, constraints and optimization, user concerns, decision support, models and ontologies, machine learning, ontology manipulation, natural language processing, and applications.
Artificial Intelligence : Applications and innovations
It's about the science of artificial intelligence (AI). AI is the study of the design of intelligent computational agents. This book provides a valuable resource for researchers, scientists, professionals, academicians and students dealing with the new challenges and advances in the areas of AI and innovations. This book also covers a wide range of applications of machine learning such as fire detection, structural health and pollution monitoring and control. Provides insight into prospective research and application areas related to industry and technology / Discusses industry- based inputs on success stories of technology adoption / Discusses technology applications from a research perspective in the field of AI / Provides a hands- on approach and case studies for readers of the book to practice and assimilate learning
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
