الصفحة 21
الصفحة 21
Geometrical dynamics of complex systems : A unified modelling approach to physics, control, biomechanics, neurodynamics and psycho-socio-economical dynamics
This volume presents a comprehensive introduction into rigorous geometrical dynamics of complex systems of various natures. By "complex systems", in this book are meant high-dimensional nonlinear systems, which can be (but not necessarily are) adaptive. This monograph proposes a unified geometrical approach to dynamics of complex systems of various kinds: engineering, physical, biophysical, psychophysical, sociophysical, econophysical, etc. The main objective of this book is to show that high-dimensional nonlinear systems in "real life" can be modeled and analyzed using rigorous mathematics, which enables their complete predictability and controllability, as if they were linear systems.
Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegenerative diseases.
Genome editing in neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Genetic control of neuronal migrations in human cortical development
Introduction Cortical development is a complex, tightly regulated process that eventually leads to the six-layered adult human neocortex, the substrate of the unique cognitive, emotional, and social abilities of our species. The basic mechanisms of early cortical development are believed to be very similar among mammals, which has led to a tendency of extrapolating experimental data from rodents on humans.
Fuzzy-Neuro Approach to Agent Applications : From the AI Perspective to Modern Ontology
The book provides a full explanation of the concepts and theories of intelligent agents and agent-based systems. Providing a comprehensive theoretical background, the author covers modern artificial intelligence topics such as ontologies, neural networks, chaos theory, fuzzy logics and genetic algorithms. Finally, the author details how the iJADK toolkit (intelligent Java agent development kit for intelligent e-business applications) can be used in the design and implementation phases of real applications.
Fundamentals of anatomy and physiology of speech, language, and hearing
Each topic is explored in bullet-point form with augmentative paragraph information, in-depth box features, and detailed illustrations. High-resolution Anatomage virtual dissection table figures derived from real cadavers offer an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors and an impressive level of detail. Topics explored include respiration, phonation, articulation, swallowing, resonance, hearing, balance, neuroanatomy, and neurophysiology.
Functional Somatic Symptoms in Children and Adolescents : A Stress-System Approach to Assessment and Treatment
This book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system
Functional Neuroanatomy of Pain
Pain is an unpleasant but very important biological signal for danger. Nociception is necessary for survival and maintaining the integrity of the organism in a potentially hostile environment. Pain is both a sensory experience and a perceptual metaphor for damage and it is activated by noxious stimuli that act on a complex pain sensory apparatus. However, chronic pain having no more a protective role can become a ruining disease itself, termed "neuropathic pain".
Functional MRI : Basic principles and clinical applications
This practical and timely volume presents an overview of the principles of fMRI and explains key concepts, including scanning methodologies, experimental research design, and data analysis. Informative discussions cover the technical and clinical challenges associated with fMRI. A neuroanatomical atlas adds to the sensible approach and serves as a useful reference by clearly illustrating normal functioning for important areas of the brain.
From Object to Experience : The New Culture of Architectural Design
Combines a history of ideas about architectural experience with the latest insights from the fields of neuroscience, cognitive science and evolutionary biology to make a powerful argument about the nature and future of architectural design. Today, the sciences have granted us the tools to help us understand better than ever before the precise ways in which the built environment can affect the building user's individual experience. Through an understanding of these tools, architects should be able to become better designers, prioritizing the experience of space - the emotional and aesthetic responses, and the sense of homeostatic well-being, of those who will occupy any designed environment. In From Object to Experience, Mallgrave goes further, arguing that it should also be possible to build an effective new cultural ethos for architectural practice. Drawing upon a range of humanistic and biological sources, and emphasizing the far-reaching implications of new neuroscientific discoveries and models, this book brings up-to-date insights and theoretical clarity to a position that was once considered revolutionary but is fast becoming accepted in architecture
FPGA Implementations of Neural Networks
During the 1980s and early 1990s there was signi?cant work in the design and implementation of hardware neurocomputers. Nevertheless, most of these efforts may be judged to have been unsuccessful: at no time have have ha- ware neurocomputers been in wide use. This lack of success may be largely attributed to the fact that earlier work was almost entirely aimed at developing custom neurocomputers, based on ASIC technology, but for such niche - eas this technology was never suf?ciently developed or competitive enough to justify large-scale adoption. On the other hand, gate-arrays of the period m- tioned were never large enough nor fast enough for serious arti?cial-neur- network (ANN) applications.
Foundations of Sport-Related Brain Injuries
A major take-home point from this book should be the assumption that symptom resolution does not necessarily mean injury resolution. As can be seen by research focusing on global metabolic cascades and neural activity of the brain, long-standing dysfunctional pathways continue to exist for extended periods of time even after a minor concussion. Until we completely understand the consequences of short-term perturbations and long-term residual brain dysfunctions, concussions must be treated with respect and given a higher priority for continued research activity.
Formative research in social marketing : Innovative methods to gain consumer insights
Brings together the state of the art and current debates in the field of formative research, and examines many of the innovative methods largely overlooked in the available literature. This book will help social marketing to move beyond surveys and focus groups.The book addresses the needs of social marketing academics and practitioners alike by providing a robust and critical academic discussion of cutting-edge research methods, while demonstrating at the same time how each respective method can help us arrive at a deeper understanding of the issues that social marketing interventions are seeking to remedy. Each chapter includes a scholarly discussion of key formative research methods.
Forensic Pathology Reviews ; Vol. 5
In this volume of the globally recognized Forensic Pathology Reviews, Dr. Michael Tsokos has gathered chapters from the top experts in the field to reveal both the applied and scientific areas of expertise along the broad spectrum of forensics studies.
Forensic pathology reviews ; Vol. 3
Maintaining the high quality achieved in earlier volumes, leading national and international forensic pathologists provide in Forensic Pathology Reviews, Volume 3 evidence-based accounts of special topics of current interest from various fields of forensic pathology and death-scene investigation. The authors offer cutting-edge insights into the medicolegal investigation of bodies found in water, the forensic aspects of the human immunodeficiency virus (HIV)-1 infection of the central nervous system, deaths in a head-down position, and forensic bitemark analysis. Additional chapters address taphonomic changes in human bodies during the early postmortem interval, arrhythmogenic ventricular dysplasia that produces sudden death in young people, the postmortem diagnosis of death in anaphylaxis, and iatrogenic deaths. The forensic aspects of suicide, murder-suicide, and suicide trends in the United States are also discussed, along with the evaluation of fatal pulmonary thromboembolism and the use of radiology in medicolegal investigations. A comprehensive, up-to-date review of the international literature is given for each chapter. Evidence-based and state-of-the-art, Forensic Pathology Reviews, Volume 3 synthesizes the practical advances made in a variety of important subspecialties of forensic pathology, demonstrating how the latest medical and scientific advances are being applied to solve current problems of high interest to forensic pathologists today.
Forensic neuropathology and associated neurology
Incorporating the most recent literature and state-of-the-art methods, this practical work and atlas covers the entire domain of neuropathology for forensic pathologists as well as for specialists in associated fields. Its concise, direct style provides the reader with succinct and easy-to-find answers to forensic, pathological, pathophysiological, biomechanical, and molecular biology problems.
Flavonoids as nutraceuticals
Flavonoids are well-known plant metabolites that have extraordinary properties that can be used for treating health issues. The pharmaceutical importance of flavonoids is due to their anti-depressant, anti-viral, anti-inflammatory, and antioxidant capacities. They are also of great importance when it comes to neuroprotection, cardiovascular disorders, and many types of cancer. Flavonoids are also easily available and produce less harmful side effects than some conventional therapeutics. This new volume examines the growing use of flavonoids for prevention and treatment of diseases and discusses their beneficial mechanisms. Chapters in the volume address diverse uses as anti-aging tools, as anti-inflammatory agents, for treating pregnancy-induced disorders, as a promising tool to combat infection of Covid-19, etc. The book explores their specific therapeutic antiviral potentials, the gene expression by flavonoids, and the role of flavonoids in agriculture.
Feldman and Pike's vitamin D; Vol. 2 : Health, disease and therapeutics
Covers the evidence for new roles of vitamin D, ranging from organ transplantation to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. The coverage is appropriately broad, drawing on aspects of internal medicine, pediatrics, nutrition, orthopedics, oncology, neurology, obstetrics and gynecology, and immunology, as well as, new areas for vitamin D including sports medicine, opthalmology, veterinary medicine and ICU care – including COVID-19. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease and better understand future directions for research in this still-growing field.
Fecal Incontinence : Diagnosis and Treatment
Fecal incontinence is a frequent, distressing condition that has a devastating impact on patients’ lives. However, patients are typically embarrassed and reluctant to acknowledge this disability, so they relinquish the possibility of being cured and remain socially isolated. Since fecal incontinence may result from various pathophysiological situations, an accurate diagnostic work-up of each patient is fundamental. Today, a wide range of therapeutic options is available, but making the correct choice is pivotal to the successful management of this condition. This book is aimed at all physicians involved in the assessment and treatment of fecal incontinence. Its main purpose is to review the latest advances in the epidemiologic, socio-economic, psychologic, diagnostic, and therapeutic aspects of fecal incontinence, in order to establish guidelines for effective treatment.
Fatigue Science for Human Health
Fatigue is quite a familiar sensation, one that everyone is likely to have experienced. Its molecular and neural mechanisms have not yet been elucidated, however, probably because of the complicated nature of its causes. To provide a broad forum for discussion, the International Conference on Fatigue Science was organized, the first being held in 2002 in Sandhamn, Sweden, and the second in 2005 in Karuizawa, Japan. Subsequently it was decided that the papers presented at the two conferences should be collected and incorporated in this pioneering work, Fatigue Science for Human Health. The book summarizes fatigue researchers' achievements, explains the status of the research on fatigue, and presents perspectives on remedies for chronic fatigue and chronic fatigue syndrome. The result is an authoritative guide to recent progress in the molecular and neural mechanisms of fatigue and in the development of the ways to prevent and overcome fatigue and chronic fatigue.
