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Amino acid biosynthesis : Pathways, regulation and metabolic engineering
Amino Acids Biosynthesis presents the current knowledge of fundamental as well as applied microbiology of amino acids. Topics discussed are the amino acid biosynthetic pathways, their genetic and biochemical regulation, transport of amino acids and genomics of producing microorganisms. The characterization of the control mechanisms of amino acid biosynthesis has revealed insights into principles of genetic and biochemical regulation, such as transcriptional regulators and a new class of regulatory elements, the riboswitch. The volume further deals with the metabolic engineering of microorganisms for the biotechnological production of amino acids for use as pharmaceuticals and, particularly, as food and feed additives.
Agroecological transitions : From theory to practice in local participatory design
There is wide agreement on the need to change the prevalent agricultural models, given their negative impacts and their incompatibility with current societal issues. Agroecological transition has been promoted as a potential solution to the ecological, social and economic problems generated by these models. It however involves a systemic, multi-scale and transdisciplinary process. Due to this complexity, the overall picture of what farms and food systems “actually are” and “might be” may not be apparent at the individual level. Yet individuals’ knowledge and values provide complementary insights on how to proceed in deepening ecological modernisation. Expertise can also provide landmarks to be considered in that process. Because local stakeholders’ experience and skills are key resources in the adaptation and adoption of agroecological transition, new conceptual and methodological frameworks and tools have to be developed to support them in the design process of such a complex transition. This book presents feedback from the ‘Territorial Agroecological Transition in Action’- TATA-BOX research project, which was devoted to these specific issues.
Agricultural Biotechnology in China : Origins and Prospects
Building on a long tradition of agricultural advances, Chinese scientists have applied biotechnology techniques to develop hundreds of novel crop varieties suited to local farming conditions and challenges.Agricultural Biotechnology in China: Origins and Prospects is a comprehensive examination of how the origins of biotechnology research agendas, along with the effectiveness of the seed delivery system and biosafety oversight, help to explain current patterns of crop development and adoption in China. Based on firsthand insights from China’s laboratories and farms, Valerie Karplus and Dr. Xing Wang Deng explore the implications of China’s investment for the nation’s rural development, environmental footprint, as well as its global scientific and economic competitiveness.
Ageing : The Paradox of Life : Why We Age
For centuries people have been puzzled by the inevitability of human aging. For most of the second half of the twentieth century aging remained a mystery, or an unsolved biological problem. At the end of the 20th century a remarkable scientific discovery emerged. It was not a single discovery in the usual sense, because it was based on a series of important interconnected insights over quite a long period of time. These insights made it possible for the very first time to understand the biological reasons for aging in animals and man. It can already be said, however, that the many observations and insights that explain aging will not be accepted as established knowledge for a long time.
Advances in Alzheimer’s and Parkinson’s Disease : Insights, Progress, and Perspectives
Proceedings of the 7th International Conference on Alzheimer’s Disease and Parkinson’s Disease (ADPD), held March 9-13, 2005 in Sorrento, Italy.The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, covering topics such as immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the history, epidemiology, clinical phenomenology, diagnosis, imaging, treatment ,and future perspectives of Alzheimer’s and Parkinson’s Diseases.
Advanced Issue Resolution in Safety Pharmacology
Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
Acute Endocrinology : From Cause to Consequence
The integration of endocrinology in critical care medicine has led to new experimental and clinical data on the complex endocrine and metabolic derangements accompanying non-endocrine severe illnesses. The joining of these two disciplines has generated important novel insights with significant clinical implications. Acute Endocrinology: From Cause to Consequence compiles these new findings into an important and highly relevant new resource.
China and the World in a Changing Context : Perspectives from Ambassadors to China
This book aims to present an overview of China and the world from diverse angles. It brings together essays by ambassadors to China on a range of bilateral and multilateral issues, including trade and investment, regional economic cooperation, sustainable development, technology and innovation, and entrepreneurship. Given their familiarity with China and extensive international experience, the insights of these ambassadors are useful for policymakers, academics, entrepreneurs, students, and anyone trying to make sense of our rapidly changing world.
AI and law : How automation is changing the law
Provides insights into how AI is changing legal practice, government processes, and individuals’ access to those processes, encouraging each of us to consider how technological advances are changing the legal system. Particularly, and distinct from current debates on how to regulate AI, this books focuses on how the progressive merger between computational methods and legal rules changes the very structure and application of the law itself.
Managing Risk and Information Security : Protect to Enable
Examine the evolving enterprise security landscape and discover how to manage and survive risk. While based primarily on the author’s experience and insights at major companies where he has served as CISO and CSPO, the book also includes many examples from other well-known companies and provides guidance for a management-level audience. Managing Risk and Information Security provides thought leadership in the increasingly important area of enterprise information risk and security. It describes the changing risk environment and why a fresh approach to information security is needed. Because almost every aspect of an enterprise is now dependent on technology not only for internal operations but increasing as a part of product or service creation, the focus of IT security must shift from locking down assets to enabling the business while managing and surviving risk. This edition discusses business risk from a broader perspective, including privacy and regulatory considerations. It describes the increasing number of threats and vulnerabilities and offers strategies for developing solutions. These include discussions of how enterprises can take advantage of new and emerging technologies—such as social media and the huge proliferation of Internet-enabled devices—while minimizing risk.
Knowledge graphs and big data processing
This book is part of the LAMBDA Project (Learning, Applying, Multiplying Big Data Analytics), funded by the European Union, GA No. 809965. Data Analytics involves applying algorithmic processes to derive insights.
Communication research into the digital society : Fundamental insights from the Amsterdam School of Communication Research
Media and communication have become ubiquitous in today’s societies andaffect all aspects of life. On an individual level, they impact how we learnabout the world, how we entertain ourselves, and how we interact withothers. On an organisational level, the interactions between media andorganisations, such as political parties, NGOs, businesses and brands, shapeorganisations’ reputation, legitimacy, trust and (financial) performance, aswell as individuals’ consumer, political, social and health behaviours. Atthe societal level, media and communication are crucial for shaping publicopinion on current issues such as climate change, sustainability, diversity,and well-being.
Building an Enterprise Architecture Practice : Tools, Tips, Best Practices, Ready-to-Use Insights
This book clearly describes how to establish an architecture practice that delivers value for an organization. The authors demonstrate a wealth of experience and a deep understanding of the multifaceted nature of this challenging task and they provide sound advice on how to avoid the many pitfalls that may be encountered along the way. Building an Enterprise Architecture Practice provides practical advice on how to develop your enterprise architecture practice.
Blockchain : Empowering Secure Data Sharing
The book explains the security architecture model and the practice of building data sharing from the blockchain infrastructure, allowing readers to understand the importance of data sharing security based on the blockchain framework, as well as the threats to security and privacy. Further, by presenting specific data sharing case studies, it offers insights into solving data security sharing problems in more practical fields. The book is intended for readers with a basic understanding of the blockchain infrastructure, consensus mechanisms, smart contracts, secure multiparty computing, homomorphic encryption and image retrieval technologies.
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Beginning Game Development with Python and Pygame : From novice to professional
Beginning Game Development with Python and Pygame is written with the budding game developer in mind, introducing games development through the Python programming language and the popular Pygame games development library. You'll be privy to insights that will not only help you to exploit Pygame to its maximum potential, but also make you a more creative and knowledgeable games developer all round.
Artificial Intelligent Techniques for Wireless Communication and Networking
Wireless communication and networking based on AI concepts and techniques are explored in this book, specifically focusing on the current research in the field by highlighting empirical results along with theoretical concepts. The possibility of applying AI mechanisms towards security aspects in the communication domain is elaborated; also explored is the application side of integrated technologies that enhance AI-based innovations, insights, intelligent predictions, cost optimization, inventory management, identification processes, classification mechanisms, cooperative spectrum sensing techniques, ad-hoc network architecture, and protocol and simulation-based environments.
AmIware : Hardware Technology Drivers of Ambient Intelligence
Ambient Intelligence is one of the new paradigms in the development of information and communication technology, which has attracted much attention over the past years. The aim is the to integrate technology into people environment in such a way that it improves their daily lives in terms of well-being, creativity, and productivity. Ambient Intelligence is a multidisciplinary concept, which heavily builds on a number of fundamental breakthroughs that have been achieved in the development of new hardware concepts over the past years. New insights in nano and micro electronics, packaging and interconnection technology, large-area electronics, energy scavenging devices, wireless sensors, low power electronics and computing platforms enable the realization of the heaven of ambient intelligence by overcoming the hell of physics.
Advances in fuzzy logic systems
Fuzzy logic systems have been a hot topic in the scientific and academic community for more than half a century. The idea of making machines behave and make decisions like humans do is astounding. The development and implementation of fuzzy logic systems can be seen in various real physical applications in daily human life. The methods employed using fuzzy logic have resulted in innovative technologies. This book provides insights into understanding the principles and concepts behind the advances of fuzzy logic systems. It presents ideas concerning fuzzy logic systems and their technological applications. The book is arranged into two sections on theories and foundations of fuzzy logic systems and implementations of fuzzy logic systems in service to the community.
