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الصفحة 2
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Linking Restoration and Ecological Succession
Recognizes the critical roles of disturbance ecology, landscape ecology, ecological assembly, invasion biology, ecosystem health, and historical ecology in habitat restoration and argues that restoration within a successional context will best utilize the lessons from each of these disciplines.
Lifestyle psychiatry through the lens of behavioral medicine
Lifestyle medicine is a practice which adopts evidence-based lifestyle interventions as a primary modality to prevent, treat, and reverse chronic diseases. The six main pillars of this specialty include physical activity, nutrition, stress resilience, cessation or risk reduction of substance use, quality sleep, and connectivity. Lifestyle psychiatry is a rapidly emerging area within healthcare informed by rigorous research within the social and biological sciences, public health, and medicine. A volume in the Lifestyle Medicine series, this book uses a comprehensive biopsychosocial approach to prevent and treat psychiatric disorders and promote mental and physical well-being through evidence-based lifestyle interventions.
Lifestyle nutrition eating for good health by lowering the risk of chronic diseases
Provides physicians with an evidence-based introduction to nutrition science with a practical emphasis on how to apply this information to improve the health of their patients and enhance their own lives. From nutrition and atherosclerosis to erectile dysfunction and chronic kidney disease to osteoporosis, this comprehensive guide covers a wide range of conditions influenced by diet. It delves into specialized areas, such as nutrition for physically active people to the elderly, ensuring relevance for diverse patient populations. The reader will find detailed analysis of the Dietary Guidelines for Americans 2020–2025 and their applications and strategies for adopting healthy plant-based diets, such as Mediterranean, DASH, and vegan.
Lifestyle nursing
Examines the concepts of lifestyle medicine and nursing practice, it is specifically designed to help nurses introduce the concepts of lifestyle medicine to readers while also encouraging them to focus on their own wellness. This book features nutritional guidelines and supplemental materials operationalizing this basic nutrition knowledge into personal and patient wellness. It addresses evidence-based findings of chronic diseases including heart diseases and stroke, type 2 diabetes, and cancers, which can often be prevented by lifestyle interventions.
Lifestyle medicine
Contains extensive sections on the treatment and prevention of coronary heart disease,stroke, cancer, diabetes, obesity, substance abuse, dementia, and many other clinical conditions. Key lifestyle modalities such as physical activity, nutrition, weight management, sleep, stress reduction, and positive connections with other humans are supported by detailed discussion and state-of-the-art evidence. The expanded section on behavioral medicine provides an important framework for these discussions. Every chapter has been completely revised and many new topics added, such as lifestyle medicine for nursing, psychiatry, and preventive neurology.
Les thérapies ciblées = Targeted therapies
We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.
Les infections urinaires = Urinary tract infections
Les Infections urinaires provides an update on knowledge concerning the epidemiology of community-based infection, on the mechanisms of bacterial resistance and on certain aspects of the disease useful to urologists as well as infectious diseases, gynecologists, emergency physicians and attending physicians. . Nosocomial urinary tract infection is approached from the perspective of risk factors. Acute and chronic prostatitis was the subject of a consensus conference supported by the World Health Organization within the framework of the International Consensus Conferences in Urology in Paris. The full text and the recommendations are reported with the consent of their authors. This book is an author's book and not an author's book because urinary tract infection is multiple, complex and justifies a multidisciplinary approach.
Les fonctions sphinctériennes = Sphincter functions
This book on Sphincter functions provides an update on a very topical subject, urinary and anal incontinence. Divided into three parts, it first deals with fundamental aspects, whether anatomical, physiological or clinical. The explorations of the various urinary and anorectal functions are described with electrophysiological, manometric, urodynamic tests as well as imaging. The second part is devoted to the pathology with all the dysfunctions that we encounter in daily practice. Urinary and anal incontinence, dysuria and retention, neurological sphincter disorders, dysfunctions in pregnant women and children are discussed. The last part takes stock of treatments, whether pharmacological, rehabilitative or surgical. This work, which contains a considerable amount of information, will undoubtedly be of interest to many medical specialists (physicians in physical medicine and rehabilitation, neurologists, gastroenterologists, gynecologists, general practitioners, pediatricians), surgeons (urologists, gynecological surgeons, surgeons). digestive) whether they are in training or already involved in the management of perineal disability. Other health professionals will find reference material there (nurses, physiotherapists, midwives).
Les cancers digestifs = Digestive cancers
Digestive tumors are among the most common malignant tumors and represent a major public health problem. This is one of the areas that has evolved the most in recent years in oncology due to significant progress in diagnostic strategies and therapeutic management. It seems essential that this progress be implemented in the daily practice of physicians treating these tumors. This book, the result of multidisciplinary work, provides a practical and up-to-date approach to the management of malignant digestive tumors. The first chapters are devoted to general and original subjects such as epidemiology, genetics, the management of elderly subjects. A second part approaches in a pragmatic and practical way the principles of diagnostic and therapeutic management by localization. A third part, devoted to the practical realization of chemotherapy, takes stock of new therapeutic approaches, oral or locoregional chemotherapy. Finally, the last part of the book is dedicated to digestive cancer emergencies and the palliative management of these tumors.
Le Distilbène trente ans après : Les enfants des 2èmes et 3èmes générations = Distilbene thirty years later : The children of the 2nd and 3rd generations
The various consequences on the anatomy and physiology of the female genitalia, as well as male, of children exposed in utero are reviewed. The impact on girls is greater than on boys: modification of the uterine cervix, reduction in the volume of the uterus with its consequences on fertility and the progress of pregnancies, risk of cancer of the vagina and the cervix. . The potential repercussions on the third generation are analyzed from experimental studies. Finally, the medico-legal implication is studied from the various trials that took place in the United States and from the first French trial that took place in Nanterre in November 2003. This work is the result of the collaboration of several experts recognized for their competence in this field. It will be of interest to all obstetrician gynecologists, urologists, but also public health physicians and midwives.
Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue
Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.
Le dépistage du cancer du col de lutérus = Cervical cancer screening
Each year, cervical cancer kills approximately 1,000 people in France, making it the fifth leading cause of cancer death and the eighth most common cancer among women. While eradicating cervical cancer is not possible, a national screening campaign should significantly reduce its incidence. This campaign should be based, in particular, on the systematic use of Pap smears. Conventional Pap smears have already reduced the number of invasive cancers by more than 50%. Improving them requires optimizing their sensitivity. This book details the natural history of cervical cancer, its incidence and mortality, and the various aspects of screening: general principles, the French screening program, the different types of Pap smears, the role and contribution of the HPV test, the management of abnormal Pap smears, the role of colposcopy, and the follow-up of treated women. It is intended for all those involved in this screening : specialist interns and gynecologists, pathologists and biologists, public health physicians, but also general practitioners whose role in screening is privileged since they are at the forefront of medical demand.
Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives
Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.
Le complicazioni neurologiche in oncologia = Neurological complications in oncology
This volume, both necessary and new in the panorama of Italian medical literature, acknowledges this and presents an updated and complete review of the pathologies of the central and peripheral nervous system associated with tumors and their treatment. The purpose of the volume is to present an integrated approach between specialists that must see the neurologist and the oncologist in dialogue, and able to develop a new super-specialized clinical capacity in neuro-oncology. Many experts have contributed to its preparation by sharing knowledge on topics ranging from metastatic complications, to those of surgical cancer therapy, radio- and chemo-therapy, paraneoplastic syndromes, pain therapy, delirium and the affective alterations associated with the disease. The book is aimed in particular at neurologists, oncologists, palliative care practitioners and surgeons, but it is certainly useful for general practitioners and all operators who are daily involved in the demanding work of taking care of cancer patients.
Le Cancer du rein = Kidney cancer
Localized tumors are discovered at an earlier stage. The concept of active surveillance emerges. Minimally invasive treatments such as cryotherapy or radiofrequency for selected cases are now available. The indications for elective open partial nephrectomy are expanding and laparoscopic and then robotic partial nephrectomy are being evaluated.
Le bouddhisme et la médecine traditionnelle de lInde = Buddhism and traditional medicine from India
Aims to return to ancient India, to the sources of Buddhism. It is a question of comparing the religious bodies of Buddhism of the origins with the treatises relating to Ayurveda, the medicine practiced in India at that time.
Lapproccio e la gestione per processi in pneumologia = The process-based approach and management in pulmonology
The topics covered are highly relevant to the application of the methods and tools outlined in quality improvement programs. This is in an effort to enhance the specific skills of the pulmonologist, thus making him an effective and independent liaison with the relevant strategic management. With great sensitivity, the SIMeR (Italian Society of Respiratory Medicine) has chosen to sponsor this edition, the only one to date in the field of Pulmonology, whose contents are based on the proposals and work of the leaders of one of its most recently established Study Groups, the "Continuous Quality Improvement in Pulmonology" Study Group.
Landscape Pattern Analysis for Assessing Ecosystem Condition
Landscape Pattern Analysis for Assessing Ecosystem Condition presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA).
Lactic acid bacteria : Methods and protocols
This updated volume presents experimentation-based approaches to lactic acid bacteria (LAB) research. Split into three parts, the book explores techniques for analyzing lactic acid bacteria metabolism and characteristics, applications for food-related industries, such as yogurt production, beer, and wine making, and functions of LAB in human health. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
