الصفحة 2
الصفحة 2
Sindrome Coronarica Acuta, un nuovo modo di fare diagnosi, un nuovo modo di impostare la terapia = Acute Coronary Syndrome : Anew way of diagnosing and setting therapy
Aims to provide the reader with a concise yet comprehensive and up-to-date overview of the issue of acute coronary syndrome, in light of the enormous body of literature published on the subject over the past decade. Introduction to the concepts of electrocardiography and histophysiopathology, the nosological reclassification of acute coronary disease resulting from the introduction of new myocardial necrosis markers into clinical practice is addressed. It also emphasizes the need for physicians to assess the intrinsic risk of the disease by calculating specific scores proposed by clinical studies. Based on these new concepts, the various therapeutic approaches that should be implemented are analyzed, including both purely pharmacological and more "aggressive" approaches in terms of effectiveness. Ample space is therefore given to the use of new antithrombotic treatments and the choice between pharmacological therapy and invasive approaches using coronary angiography and angioplasty. a crossroads that sometimes puts the doctor in difficulty, but which can imply, if the options are faced rationally, a radical change in the patient's destiny.
Sexually Transmitted Diseases : A Practical Guide for Primary Care
Sexually Transmitted Diseases: A Practical Guide for Primary Care covers the diagnosis and treatment of STDs and other information critical to patient care in the new millennium. This collaboration provides the clinician with the ability to identify and manage Sexually Transmitted Infections (STIs), as well as obtain information about preventing their sequelae. Among the topics covered in this book are human papillomavirus and genital warts, genital herpes, viral hepatitis, HIV infection and AIDS, chlamydial and gonorrheal infections, and upper genital tract infections in women. Other topics of interest include syphilis, trichomoniasis, chancroid, granuloma inguinale, lymphogranuloma venereum, and molluscum contagiosum. Special consideration is given to ectoparasites, patient-clinician communication and STD care, cultural competence and STI care, effectiveness of barrier methods for STI prevention, and the future role of vaccines and microbides.
Sensitization of Cancer Cells for Chemo/immuno/Radio-therapy
Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy, edited by Benjamin Bonavida, reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. Such sensitizing agents target gene products that regulate resistance and therefore identify novel targets for drug development. This book also introduces several of the current approaches that have been developed by established investigators in the field that are aimed at overcoming resistance. This book is the first that compiles studies on tumor cell sensitization and is useful for students, scientists, clinicians and pharmaceutical companies.
Secondary Analysis of Electronic Health Records
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence.
Scenario Logic and Probabilistic Management of Risk in Business and Engineering
In this volume the methodological aspects of the scenario logic and probabilistic (LP) non-success risk management are considered. The theoretical bases of scenario non-success risk LP-management in business and engineering are also stated. Methods and algorithms for the scenario risk LP-management in problems of classification, investment and effectiveness are described. Risk LP- models and results of numerical investigations for credit risks, risk of frauds, security portfolio risk, risk of quality, accuracy, and risk in multi-stage systems reliability are given. In addition, a rather large number of new problems of estimation, analysis and management of risk are considered. Software for risk problems based on LP-methods, LP-theory, and GIE are described too.
Scarcity Marketing : Impact of Limited-ed. Packaging on Purchase Intentions in The Syrian Market
The Syrian market have relied on the basic scarcity product tactics, but creativity and uniqueness have become more in need, hence that is what this paper aims at delivering by evaluating the effectiveness of limited-edition packaging as a scarcity product tactic. The purpose of this study is to examine the effect of scarcity messages on the consumer’s purchase intention. Specifically, we explore the effect of LEP’s on the consumer’s purchase intention using limited time, limited quantity and FOMO as moderators. how they affect the purchase intention of consumers, and how the feeling of ‘Fear of Missing Out’ (FOMO) does influence this relationship. For this research, an online questionnaire has been conducted among 306 participants, focused within the context of food and beverages. The results show that there is positive impact of LEPs on consumer purchase intentions, in addition to the positive moderation effect that was founded, strengthening the relationship furthermore.
Routing Congestion in VLSI Circuits : Estimation and Optimization
Routing Congestion in VLSI Circuits: Estimation and Optimization provides the reader with a complete understanding of the root causes of routing congestion in present-day and future VLSI circuits, available techniques for estimating and optimizing this congestion, and a critical analysis of the accuracy and effectiveness of these techniques, so that the reader may prudently choose an approach that is appropriate to their design goals. The scope of the work includes metrics and optimization techniques for routing congestion at various stages of the VLSI design flow, including the architectural level, the logic synthesis/technology mapping level, the placement phase, and the routing step. A particular focus of this work is on the congestion issues that deal primarily with standard cell based design.
Reliability-based Structural Design
Reliability-based Structural Design provides readers with an understanding of the fundamentals and applications of structural reliability, stochastic finite element method, reliability analysis via stochastic expansion, and optimization under uncertainty. Probability theory, statistic methods, and reliability analysis methods including Monte Carlo sampling, Latin hypercube sampling, first and second-order reliability methods, stochastic finite element method, and stochastic optimization are discussed. In addition, the use of stochastic expansions, including polynomial chaos expansion and Karhunen-Loeve expansion, for the reliability analysis of practical engineering problems is also examined. Detailed examples of practical engineering applications including an uninhabited joined-wing aircraft and a supercavitating torpedo are presented to illustrate the effectiveness of these methods.
Rehabilitation and palliation of cancer patients : (Patient care)
To maintain quality of life is an important challenge not only for health aftercare service, but also in palliative and terminal situations. The invasiveness of some of the current therapies and the restricted life expectancy of many patients led to the change in therapeutic paradigms. Rehabilitation and palliation have become an essential part of modern comprehensive cancer care. There are many excellent text books in cancer management which provide therapeutic recommendations thereby influencing the disease. Quality of life is now the second parameter after survival used to evaluate the effectiveness of first line oncologial therapies and is still the first parameter of most therapies in the case of recurrence. It contains experiences of the author and specific instructions how to assess, treat and evaluate rehabilitative and palliative measures.
Rational cybersecurity for business : The security leaders' guide to business alignment
This book presents six priority areas to focus on to maximize the effectiveness of your cybersecurity program: risk management, control baseline, security culture, IT rationalization, access control, and cyber-resilience. Common challenges and good practices are provided for businesses of different types and sizes. And more than 50 specific keys to alignment are included.
Rapid Integration of Software Engineering Techniques ; Vol. 3475 : 1st International Workshop, RISE 2004, Luxembourg-Kirchberg, Luxembourg, November 26, 2004, Revised Selected Papers
This paper reports on the experiences of integrating several Software Engineering techniques by the Rapid Prototyping group of Siemens Corporate Research. This experience was gained during our recent project that involved developing a web-based, workflow-driven information system. The techniques integrated for this project included agile and iterative processes, user centered design, requirements discovery and maturation, and test-driven development. These techniques were integrated and supported by a proprietary process entitled “Siemens Rapid Prototyping” (S-RaP), a software architecture, and project management techniques. This paper will detail the specific characteristics of S-RaP, the software architecture, and the project management techniques that supported the integration of the above listed software engineering techniques. We will also report on our experience with their effectiveness and our thoughts on future enhancements in all three areas
Quantified Eco-Efficiency : An Introduction with Applications
A central asset of eco-efficiency analysis is that it does not depend on a specific evaluation of environmental impacts against economic effects. Several evaluation methods may be used, including those based on willingness-to-pay, panel procedures, and public statements on policy goals
Qualità dei Dati : Concetti, Metodi e Tecniche = Data quality: Concepts, Methods and Techniques
Poor data quality can hinder or seriously damage the efficiency and effectiveness of organizations and businesses. The growing awareness of these repercussions has led to important public initiatives such as the promulgation of the "Data Quality Act" in the United States and the Directive 2003/98 of the European Parliament. The authors present a complete and systematic introduction to the wide range of problems related to data quality. The book starts with a detailed description of different dimensions of data quality, such as accuracy, completeness and consistency, and discusses its importance in relation to both different types of data, such as federated data, data present on the web and data with temporal dependencies, which to the different categories in which the data can be classified. The comprehensive description of techniques and methodologies from not only research in the area of data quality but also related areas, such as data mining, probability theory, statistical data analysis and machine learning, provides an excellent introduction to the state of the art. current art. The presentation is complemented by a short description and a critical comparison of practical tools and methodologies, which will help the reader to solve their quality problems.
Psychosocial Interventions for Chronic Pain : In Search of Evidence
This book fills a major gap in the practice literature for healthcare professionals engaged in providing psychosocial care for their patients suffering from chronic pain or illness. Ranjan Roy’s introductory chapters explain how effectiveness is measured in psychosocial practice, and these concepts are clearly applied in compelling case examples, including: Family and couple therapy for longstanding pain issues. / Psychodynamic psychotherapy in a case of abuse and chronic pain. / Interpersonal psychotherapy for identity issues following a hysterectomy. / Cognitive-behavioral therapy for "immobilizing" pain. / Grief therapy following catastrophic loss. / Multidisciplinary approaches to complex chronic pain.
Progress and Confusion : The State of Macroeconomic Policy
The chapters address whether we have entered a "new normal" of low growth, negative real rates, and deflationary pressures, with contributors taking opposing views; whether new financial regulation has stemmed systemic risk; the effectiveness of macro prudential tools; monetary policy, the choice of inflation targets, and the responsibilities of central banks; fiscal policy, stimulus, and debt stabilization; the volatility of capital flows; and the international monetary and financial system, including the role of international policy coordination.
Production Planning in Production Networks : Models for Medium and Short-term Planning
Production Planning in Production Networks addresses production planning problems in distributed manufacturing networks from strategic, tactical, organisational and operative perspectives. New methodologies for capacity negotiation, allocation and workload assignment in production networks are presented. Specifically, three main problems are focussed on: how to negotiate production capacity availability in the long-term; how to allocate production capacity in medium-term planning; and, how to assign workloads in the short-term. The proposed approaches are based on negotiation algorithms in multi-agent networks. These approaches are compared with classical centralised approaches using discrete event simulation methodologies. Benchmark analysis is provided to understand the effectiveness and efficiency of the proposed approaches.
Prodrug Design : Perspectives, Approaches and Applications in Medicinal Chemistry
Provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference.
Principles of management : Efficiency and effectiveness in the private and public sector
Shows an overview of how the activities of an organisation can be managed to satisfy the needs of stakeholders through the cost effective, operationally efficient and sustainable transformation of resources into outputs. Taking an interdisciplinary approach, the authors show the relationship between management and economics and within this framework present the key areas of management activity. Also explains the connections between these areas and provides tools and instruments for successful management. The book's approach and content is relevant for all kinds of organisation - private or public sector, service or manufacturing, non-profit, large or small.
Primary Retinal Detachment : Options for Repair
This information-packed volume is the ultimate guide for today’s vitreo-retinal surgeon. It is written by leading experts in the field. The book begins with an extensive review, analyzing the evolution of present-day detachment surgery over the past 70 years. Here, a changing pattern of treatment modalities comes into view, with four primary procedures in use at the beginning of the twenty-first century. Experts in the field of retinal and vitreous surgery then describe the following surgical techniques: cerclage with drainage, pneumatic retinopexy, primary vitrectomy, and minimal segmental buckling without drainage. The advantages and disadvantages of each technique are assessed in relation to case selection, single operation attachment, final attachment, complications, visual function, and cost effectiveness.
Preventing Crime : What Works for Children, Offenders, Victims and Places
Crime prevention should be rational and should be based on the best possible evidence. Decision-makers should weigh heavily any available evidence on what works best. How can a program that has produced no discernable evidence of effectiveness, as shown through numerous evaluations, be considered for implementation? Unfortunately, this happens all the time. Evidence-based crime prevention attempts to overcome this and other obstacles by ensuring that the best available evidence is considered in any decision to implement a program designed to prevent crime. This book is about evidence-based crime prevention.
