الصفحة 2
الصفحة 2
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Breast cancer ; 2nd ed.

This book highlights M. D. Anderson Cancer Center’s multidisciplinary approach and reviews the entire spectrum of patient care, from prevention and screening through diagnosis and treatment through posttreatment follow-up and survivorship issues.

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Breast cancer : Nuclear medicine in diagnosis and therapeutic options

This book provides general information on breast cancer management and considers all new methods of diagnosis and therapy. It focuses on nuclear medicine modalities by comparing their results with other diagnostic and therapeutic approaches.

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Biologie und epidemiologie der hormonersatztherapie : Diskussionen zur postmenopausalen gesundheit = Biology and epidemiology of hormone replacement therapy : Discussions on postmenopausal health

The advantages and disadvantages of hormone replacement therapy (HRT) are discussed by a group of experts with regard to the epidemiological evidence. However, the focus of the discussion is the problem of breast cancer risk. Among other things, it is shown that the results derived from epidemiological studies do not coincide with the growth characteristics of these tumors, so that further population studies with the inclusion of pathobiological expertise appear necessary. The benefits and risks of hormone replacement therapy (HRT) are discussed by a group of experts with a view towards the evidence provided by recent epidemiological studies. Although all aspects of HRT indications and contra-indications are reviewed, the particular emphasis of this discussion is on breast cancer. Among other things, it is shown that the evidence on breast cancer provided in epidemiological studies does not match the growth characteristics of the tumors, and that further population research incorporating pathobiological assessments is required.

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Aromatase Inhibitors

Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.

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Aromatase Inhibitors

Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.

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AJCC Atlante per la stadiazione dei tumori maligni = Atlas for the Staging of Malignant Tumors

he atlas contains over 400 specially created black and white illustrations describing the anatomical extent of the malignant tumor in the primary site (T), regional lymph nodes (N) and distant metastases (M) for various sites, including the head and neck area, the digestive system, the thorax, the musculoskeletal system, the soft tissues, the breast, the urinary system and the genital system. Each illustration provides precise and detailed descriptions designed to clarify the crucial anatomical structures and to provide the reader with an immediate view of the progressive extension of the disease. The most important anatomical structures are identified by specific definitions.

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Advances in Breast Cancer Management, 2nd ed.

Advances in Breast Cancer Management, Second Edition will highlight many of the important advances that have transformed our understanding of the biology and therapeutics of breast cancer.

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Accelerated Partial Breast Irradiation : Techniques and Clinical Implementation

Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text will be a concise handbook designed to assist the clinician in the implementation of APBI.

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Artificial neural networks : Recent advances, new perspectives and applications

This book explores the potential of ANNs for applications in different fields. Itincludes eight chapters that discuss deep learning, ANN tools, and other cutting-edgetechnologies. It also suggests avenues for further research into ANN techniques formedical imaging to detect breast tumors, classification of COVID-19 surveillancedatasets, health management, estimation of materials processing parameters, solarenergy management, and control of a petrochemical unit.

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Alternative breast imaging : Four model-based approaches

Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).

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Algorithms for Decision Making

A broad introduction to algorithms for decision making under uncertainty, introducing the underlying mathematical problem formulations and the algorithms for solving them. Automated decision-making systems or decision-support systems—used in applications that range from aircraft collision avoidance to breast cancer screening—must be designed to account for various sources of uncertainty while carefully balancing multiple objectives. This textbook provides a broad introduction to algorithms for decision making under uncertainty, covering the underlying mathematical problem formulations and the algorithms for solving them.

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Advancement of Deep Learning and its Applications in Object Detection and Recognition

In just the past five years, deep learning has taken the world by surprise, driving rapid progress in fields as diverse as computer vision, natural language processing, automatic speech recognition, etc. This book presents an introduction to deep learning and various applications of deep learning such as recommendation systems, text recognition, diabetic retinopathy prediction of breast cancer, prediction of epilepsy, sentiment, fake news detection, software defect prediction and protein function prediction.

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Laser Spectroscopy : Vol.2 Experimental Techniques

Keeping abreast of the latest techniques and applications, this new edition of the standard reference and graduate text on laser spectroscopy has been completely revised and expanded. While the general concept is unchanged, the new edition features a broad array of new material, e.g. frequency doubling in external cavities, reliable cw-parametric oscillators, tunable narrow-band UV sources, more sensitive detection techniques, tunable femtosecond and sub-femtosecond lasers (X-ray region and the attosecond range), control of atomic and molecular excitations, frequency combs able to synchronize independent femtosecond lasers, coherent matter waves, and still more applications in chemical analysis, medical diagnostics, and engineering.

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Laser Spectroscopy : Vol.1 Basic Principles

Keeping abreast of the latest techniques and applications, this new edition of the standard reference and graduate text on laser spectroscopy has been completely revised and expanded. While the general concept is unchanged, the new edition features a broad array of new material, e.g., frequency doubling in external cavities, reliable cw-parametric oscillators, tunable narrow-band UV sources, more sensitive detection techniques, tunable femtosecond and sub-femtosecond lasers (X-ray region and the attosecond range), control of atomic and molecular excitations, frequency combs able to synchronize independent femtosecond lasers, coherent matter waves, and still more applications in chemical analysis, medical diagnostics, and engineering.

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Air Pollution Modeling and Its Application XIX

The book is aimed at researchers and government policy makers who wish to keep abreast of the most recent developments in air pollution modelling and air quality issues. The book emphasizes the following key topics: 1. Local and urban scale modelling; 2. Regional and intercontinental modelling; 3. Data assimilation and air quality forecast; 4. Model assessment and verification; 5. Aerosols in the atmosphere; 6. Interactions between air quality and climate change; 7. Air quality and human health.

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Advanced computer simulation approaches for soft matter sciences II

This series presents critical reviews of the present and future trends in polymer and biopolymer science including chemistry, physical chemistry, physics and materials science. It is addressed to all scientists at universities and in industry who wish to keep abreast of advances in the topics covered.The second volume contains four contributions, and has a very strong topical focus on long range interactions.

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