الصفحة 2
الصفحة 2
One Hundred Years of Chemical Warfare : Research, Deployment, Consequences
On April 22, 1915, the German military released 150 tons of chlorine gas at Ypres, Belgium. Carried by a long-awaited wind, the chlorine cloud passed within a few minutes through the British and French trenches, leaving behind at least 1,000 dead and 4,000 injured. This chemical attack, which amounted to the first use of a weapon of mass destruction, marks a turning point in world history. The preparation as well as the execution of the gas attack was orchestrated by Fritz Haber, the director of the Kaiser Wilhelm Institute for Physical Chemistry and Electrochemistry in Berlin-Dahlem. During World War I, Haber transformed his research institute into a center for the development of chemical weapons (and of the means of protection against them).
Ondansetron Patches
The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.
Oncologic and Cardiologic PET/CT-Diagnosis : An Interdisciplinary Atlas and Manual
Since 1999/2000 simultaneous imaging of anatomical features and metabolic activities using fused PET and CT images has complemented and in many cases even replaced what was originally done as separate analysis. – Is this a small revolution? – In fact, this new approach can be considered to be without a rival for imaging diagnosis. The complementary efforts of nuclear medicine physicians and radiologists have improved the diagnostic value of PET/CT scans. The successful use of PET/CT in the field of oncology has been documented world-wide, and in cardiology we can take advantage of the significant findings of PET diagnosis, particularly in the USA. New prospects are now available for paediatric oncology and molecular medicine.
Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
Once upon a time : illustrations from fairytales, fables, primers, pop-ups, and other children's books
The 1905 obituary of John McLoughlin, Jr., in Publisher's Weekly declared,?Every child in the land knows the McLoughlin books. ... In fact, the history in the last decade of colored toy books for youngsters is the history of Mr. McLoughlin and his firm.?
On the Way to the Web : The Secret History of the Internet and its Founders
On the Way to the Web: The Secret History of the Internet and Its Founders is an absorbing chronicle of the inventive, individualistic, and often cantankerous individuals who set the Internet free. Michael A. Banks describes how the online population created a new culture and turned a new frontier into their vision of the future. This book will introduce you to the innovators who laid the foundation for the Internet and the World Wide Web, the man who invented online chat, and the people who invented the products all of us use online every day. Learn where, when, how and why the Internet came into being, and exactly what hundreds of thousands of people were doing online before the Web. See who was behind it all, and what inspired them.
On the Uniqueness of Humankind
Europäische Akademie organized the conference "The Uniqueness of Humankind – Über die Sonderstellung des Menschen". The proceedings of the conference documented in this volume approached the theoretical and practical concept of the "Sonderstellung" against the background of present day knowledge in biosciences.
On the Topology of Isolated Singularities in Analytic Spaces
The aim of this book is to give an overview of selected topics on the topology of real and complex isolated singularities, with emphasis on its relations to other branches of geometry and topology. The first chapters are mostly devoted to complex singularities and a myriad of results spread in a vast literature, which are presented here in a unified way, accessible to non-specialists. Among the topics are the fibration theorems of Milnor; the relation with 3-dimensional Lie groups; exotic spheres; spin structures and 3-manifold invariants; the geometry of quadrics and Arnold's theorem which states that the complex projective plane modulo conjugation is the 4-sphere. The second part of the book studies pioneer work about real analytic singularities which arise from the topological and geometric study of holomorphic vector fields and foliations. In the low dimensional case these turn out to be related to fibred links in the 3-sphere defined by meromorphic functions. This provides new methods for constructing manifolds equipped with a rich geometry.
On the path to AI : Law’s prophecies and the conceptual foundations of the machine learning age
This book explores machine learning and its impact on how we make sense of the world. It does so by bringing together two ‘revolutions’ in a surprising analogy: the revolution of machine learning, which has placed computing on the path to artificial intelligence, and the revolution in thinking about the law that was spurred by Oliver Wendell Holmes Jr in the last two decades of the 19th century.
On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, OnToContent, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007,
it is clear that there is an acute and increasing need to address and discuss in an integrated forum the implied software and system issues as well as methodological, semantical, theoretical and application issues. As we all know, e-mail, the Internet, and even video conferences are not sufficient for effective and efficient scientific exchange. This is why the OnTheMove (OTM) Federated Conferences series has been created to cover the increasingly wide yet closely connected range of fundamental technologies such as data and Web Semantics.
On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, On To Content, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part II
This two-volume set LNCS 4805/4806 constitutes the refereed proceedings of 10 international workshops and papers of the OTM Academy Doctoral Consortium held as part of OTM 2007 in Vilamoura, Portugal, in November 2007. The first volume begins with 23 additional revised short or poster papers of the OTM 2007 main conferences.
On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol.4278 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF ,IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS,SWWS,SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part II
This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.
On the move to meaningful internet systems 2006 : OTM 2006 Workshops ; Vol. 4277 ; OTM Confederated International Conferences and Posters, AWeSOMe, CAMS, COMINF, IS, KSinBIT, MIOS-CIAO, MONET, On To Content, ORM, PerSys, OTM Academy Doctoral Consortium, RDDS, SWWS, SeBGIS 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part I
This two-volume set LNCS 4277/4278 constitutes the refereed proceedings of 14 international workshops held as part of OTM 2006 in Montpellier, France in October/November 2006. The 191 revised full papers presented were carefully reviewed and selected from a total of 493 submissions to the workshops. The first volume begins with 26 additional revised short or poster papers of the OTM 2006 main conferences.
On the move to meaningful internet systems 2006 : CoopIS, DOA, GADA, and ODBASE ; Vol. 4276 ; OTM Confederated International Conferences, CoopIS, DOA, GADA, and ODBASE 2006, Montpellier, France, October 29 - November 3, 2006, Proceedings, Part II
A two-volume set, which constitutes the refereed proceedings of the four confederated conferences CoopIS 2006, DOA 2006, GADA 2006, and ODBASE 2006 held as OTM 2006 in Montpellier, France. It contains 106 revised full and 9 short papers, which were carefully reviewed and selected from a total of 361 submissions.
On the move to meaningful internet systems : OTM 2008 Workshops ; OTM Confederated International Workshops and Posters, ADI, AWeSoMe, COMBEK, EI2N, IWSSA, MONET, OnToContent + QSI, ORM, PerSys, RDDS, SEMELS, and SWWS 2008, Monterrey, Mexico, November 9-14, 2008. Proceedings
This volume constitutes the refereed proceedings of 13 international workshops held as part of OTM 2008 in Monterrey, Mexico, in November 2008.The 106 revised full papers presented were carefully reviewed and selected from a total of 171 submissions to the workshops. The volume starts with 19 additional revised poster papers of the OTM 2008 main conferences CoopIS and ODBASE. Topics of the workshop papers are ambient data integration (ADI 2008), agents and web services merging in distributed environment (AWeSoMe 2008), community-based evolution of knowledge-intensive systems (COMBEK 2008), enterprise integration, interoperability and networking (EI2N 2008), system/software architectures .
On the Moon : The Apollo Journals
This book explains how the Apollo crews learned to work on the lunar surface. Its lively and informative text draws heavily on transcripts and photographs to illustrate points. It puts the reader on the lunar surface with the astronauts, sharing their observations, excitement, and frustrations.
On the construction of engineering handbooks : With an Illustration from the railway safety domain
This book is the first to reflect upon the question of how to construct a desktop handbook. It is demonstrated how concept analysis can be used for identifying settled knowledge as the key ingredient by utilizing the assembled data for classification; a presentation scheme for handbook articles is developed and demonstrated to be suitable. The sketched approach is then illustrated by an example from the railway safety domain. Finally, the limitations of the presented methods are discussed.
On color
Investigates color from numerous perspectives: literary, historical, cultural, anthropological, philosophical, art historical, political, and scientific. In ten lively and wide-ranging chapters, each devoted to a different color, they examine the various ways colors have shaped and continue to shape our social and moral imaginations. Each individual color becomes the focal point for a consideration of one of the extraordinary ways in which color appears and matters in our lives. Beautifully produced in full color, this book is a remarkably smart, entertaining, and fascinating guide to this elusive topic.
On Bypass : Advanced Perfusion Techniques
With the introduction of cardiac surgery more than five decades ago and the use of the heart-lung machine for open heart surgical procedures granting the surgeon unlimited time in which to operate inside the heart, a complex task has been given to the Perfusionist. With a pairing of a perfusionist and a surgeon for each chapter, On Bypass: Advanced Perfusion Techniques is an essential collection of techniques and protocols to aid in the difficult and immediate decision making in the operating room. Among the topics covered in this comprehensive text are pediatric perfusion techniques for complex congenital, separation from cardiopumonary bypass, blood flow during cardiopumonary bypass, and minimally invasive perfusion techniques. Also covered is ultrafiltration in cardiac surgery, echocardiography and cardiopulmonary bypass, and advances in long-term pulmonary support.
