Human Drug Metabolism
The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this fast moving field and its clinical impact.
Human Challenge Studies in Endemic Settings : Ethical and Regulatory Issues
This book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide
Hubble : 15 Years of Discovery
This book forms part of the European Space Agency’s 15th anniversary celebration activities for the 1990 launch of the NASA/ESA Hubble Space Telescope. As an observatory in space, Hubble is one of the most successful scientific projects of all time, both in terms of scientific output and its immediate public appeal.Hubble creates an enormous impact by exploiting a unique scientific niche where no other instruments can compete. It consistently delivers super-sharp images and clean, uncontaminated spectra over the entire near-infrared and ultraviolet regions of the electromagnetic spectrum. This has opened up new scientific territory and resulted in many paradigm-breaking discoveries.
How the stock market works : A beginner's guide to investment
Cuts through the complex jargon that can alienate newcomers by providing a clear and accessible overview on how the stock market and investing works / Provides guidance on how to safely invest, and covers the responsibilities of being a shareholder to the taxation regime / New to this edition: incorporates changes and fluctuations from 2021 onwards, including the UK's exit from the EU as well as the rise of fake news and its' impact on the financial world and decision making
How Apollo flew to the moon
Out of the technological battlefield of World War II came a team of gifted German engineers and designers who developed the vengeance weapon, the V-2, which evolved into the peaceful, powerful Saturn V rocket to take men to the Moon. David Woods tells the exciting story, starting from America’s post war astronautical research facilities, that used the V-2 for the development of the robust, resilient and reliable Saturn V launcher. He describes the initial launches through manned orbital spaceflights, comprehensively detailing each step, including computer configuration, the role of ground control, trajectory planning, lunar orbiting, separation of the lander, walking and working on the Moon, retrieval of the lunar astronauts and returning to Earth in this massive technical accomplishment.
How AI Impacts Urban Living and Public Health ; 17th International Conference, ICOST 2019, New York City, NY, USA, October 14-16, 2019, Proceedings
This book cover topics such as: e-health technology design; well-being technology; biomedical and health informatics; and smart environment technology.
Housing Estates in Europe : Poverty, Ethnic Segregation and Policy Challenges
Explores the formation and socio-spatial trajectories of large housing estates in Europe. Are these estates clustered or scattered? Which social groups originally had access to residential space in housing estates? What is the size, scale and geography of housing estates, their architectural and built environment composition, services and neighbourhood amenities, and metropolitan connectivity? How do housing estates contribute to the urban mosaic of neighborhoods by ethnic and socio-economic status? What types of policies and planning initiatives have been implemented in order to prevent the social downgrading of housing estates?The collection of chapters in this book addresses these questions from a new perspective previously unexplored in scholarly literature. The social aspects of housing estates are thoroughly investigated (including socio-demographic and economic characteristics of current and past inhabitants; ethnicity and segregation patterns; population dynamics; etc.), and the physical composition of housing estates is described in significant detail (including building materials; building form; architectural and landscape design; built environment characteristics; etc.).
Housing Contemporary Ireland : Policy, Society and Shelter
This book, the first comprehensive review of housing in Ireland for many years, introduces, in an accessible manner, the key housing developments since the foundation of the State and also reports on the findings of the latest research on the transformation of the sector in the past decade. The issues examined here include: -the impact of the house price boom on wealth and affordability / -the urban renewal schemes and private rented housing -the management of social housing / -the accommodation of Travellers and homeless people -rural housing policy and politics
Hot Property : The Housing Market in Major Cities
This book discusses booming housing markets in cities around the globe, and the resulting challenges for policymakers and central banks. Cities are booming everywhere, leading to a growing demand for urban housing. In many cities this demand is out-pacing supply, which causes house prices to soar and increases the pressure on rental markets. These developments are posing major challenges for policymakers, central banks and other authorities responsible for ensuring financial stability, and economic well-being in general. This volume collects views from high-level policymakers and researchers, providing essential insights into these challenges, their impact on society, the economy and financial stability, and possible policy responses. The respective chapters address issues such as the popularity of cities, the question of a credit-fueled housing bubble, the role of housing supply frictions and potential policy solutions. Given its scope, the book offers a revealing read and valuable guide for everyone involved in practical policymaking for housing markets, mortgage credit and financial stability.
Hosting server management
At a high level, this project involves building and configuring a hosting server to provide website, email, and FTP hosting services to customers. The project also includes building a website where customers can register an account, choose hosting packages, and manage their hosting plan by linking the website to the hosting server's control panel using APIs. To effectively manage the hosting server and provide reliable hosting services to customers, it is important to have a deep understanding of the technologies and protocols involved in web hosting. This includes knowledge of web server software, email protocols, FTP protocols, and security best practices.
Hospitality marketing and consumer behavior : Creating memorable experiences
Drawing on global experiences, this new book, Hospitality marketing and consumer behavior: Creating memorable experiences, looks at the diverse factors that create these positive experiences and provides insight into marketing and consumer behavior in the context of hospitality and tourism. The dynamics of emerging economies has been captured, and some lessons have been drawn from best practices across the globe. The book covers marketing research, different elements of the marketing mix, consumer feedback and recovery, technology, people aspects, and how they impact consumer experience.
Hormones and the brain
Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.
Homotopy Methods in Topological Fixed and Periodic Points Theory
The notion of a fixed point plays a crucial role in numerous branches of mat- maticsand its applications. Informationabout the existence of such pointsis often the crucial argument in solving a problem. In particular, topological methods of fixed point theory have been an increasing focus of interest over the last century. These topological methods of fixed point theory are divided, roughly speaking, into two types. The ?rst type includes such as the Banach Contraction Principle where the assumptions on the space can be very mild but a small change of the map can remove the fixed point. The second type, on the other hand, such as the Brouwer and Lefschetz Fixed Point Theorems, give the existence of a fixed point not only for a given map but also for any its deformations. This book is an exposition of a part of the topological fixed and periodic point theory, of this second type, based on the notions of Lefschetz and Nielsen numbers. Since both notions are homotopyinvariants, the deformationis used as an essential method, and the assertions of theorems typically state the existence of fixed or periodic points for every map of the whole homotopy class, we refer to them as homotopy methods of the topological fixed and periodic point theory.
Homology modeling : Methods and protocols
It Provides state-of-the-art methodologies and reviews of important topics in the field of homology modeling. From homology modeling in the twilight zone and improving accuracy through sequence space analysis to approaches to construct multi-protein complex models, the book explores a wide variety of uses and applications of this valuable technique.
Homocysteine : Related Vitamins and Neuropsychiatric Disorders
There is an increasing interest in the connection between the homocysteine metabolism and neuropsychiatric disease with a steeply increasing number of publications. In particular, the association between homocysteine metabolism and cognitive decline/dementia attracts much interest. If simple, non-toxic homocysteine-lowering treatment with vitamins can reduce the incidence of, or delay the onset of dementia, it would have an enormous impact in societies with a rapidly increasing number of elderly at risk for dementia. This book summarises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects.
Homo Oeconomicus : The Economic Model of Behaviour and Its Applications in Economics and Other Social Sciences
The economic model of behaviour is fundamental not only in economic theory, but also in modern approaches of other social sciences, above all in political science and law. This book provides a comprehensive treatise of the general model, its philosophical and methodological foundations and its applications in different fields. In addition to the basic model, extensions to its assumptions are examined to account for complex applications like low-cost situations with moral behaviour. Finally, the book takes a broader perspective by evaluating the impact of the model on economic policy and on the development of the field of social science as a whole, such as the competition between individualistic and collectivist approaches.
Home-oriented informatics and telematics ; Proceedings of the IFIP WG 9.3 HOIT2005 Conference
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
Home Long-Term Oxygen Treatment in Italy : The Additional Value of Telemedicine
This book, edited by Roberto W. Dal Negro and Allen I. Goldberg, gives us a full account of the impact of the telemedicine system on H-LTOT. According to the information in this book, we have to begin to think about the possibility of using telemonitoring in H-LTOT in a really general manner. In fact, telemonitoring allows better control of the compliance of patients suffering from respiratory failure, and this means a better clinical condition and longer survival, both linked to the long-term administration of oxygen. Moreover, it also permits a reduction in expenditure for the management of patients under LTOT.
Home decorating for dummies
All the information you need to know about décor into one easy-to-read source. Whether you want to decorate one room or make over the whole house, this book has everything you need to design like a pro. This is the only reference you’ll need to transform your home into a space you’ll love. Dummies offers no-nonsense help, so you can plan perfect projects and stay within budget. Updated with the latest on smart homes, short-term rentals, DIY décor, and more. Learn how to optimize your home’s floor plan Discover tricks for mixing patterns, colors, and textures successfully Refresh your home’s style without spending a fortune Decorate rental properties with eye-catching, trendy style Untangle the terms—mid-century modern, farmhouse, minimalism—and pinpoint your design style
Holomorphic Morse Inequalities and Bergman Kernels
The main analytic tool is the analytic localization technique in local index theory developed by Bismut-Lebeau. The book includes the most recent results in the field and therefore opens perspectives on several active areas of research in complex, Kähler and symplectic geometry. A large number of applications are included, e.g., an analytic proof of the Kodaira embedding theorem, a solution of the Grauert-Riemenschneider and Shiffman conjectures, a compactification of complete Kähler manifolds of pinched negative curvature, the Berezin-Toeplitz quantization, weak Lefschetz theorems, and the asymptotics of the Ray-Singer analytic torsion.



















