الصفحة 16
الصفحة 16
Fundamentals of drug delivery
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems. Provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery.
Fundamentals of Cancer Detection, Treatment, and Prevention
The book offers a comprehensive overview of cancer in humans, from its causes, symptoms, and diagnosis to the variety of treatment options available today. Intuitively organized by cancer type, this guide provides concise information on risk factors, diagnosis, and treatment options for all commonly encountered tumors, including surgery, radiation therapy, chemotherapy, and immunotherapy.
Fundamentals of anatomy and physiology of speech, language, and hearing
Each topic is explored in bullet-point form with augmentative paragraph information, in-depth box features, and detailed illustrations. High-resolution Anatomage virtual dissection table figures derived from real cadavers offer an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors and an impressive level of detail. Topics explored include respiration, phonation, articulation, swallowing, resonance, hearing, balance, neuroanatomy, and neurophysiology.
Fundamentals of analytical toxicology : Clinical and forensic ; 2nd ed.
An integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. Focuses on analytical, statistical, and pharmacokinetic principles / Describes basic methodology, including colour tests and immunoassay and enzyme-based assays / Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation / Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides / Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS)
Functional Hydrogels in Drug Delivery : Key Features and Future Perspectives
Deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed--whether natural and synthetic--and the improvement, such as modifications of synthetic approach and polymerization technique, of their physicochemical and biological properties to synthetize high performing carriers for specific uses, i.e. stimuli-responsive materials, molecularly imprinted polymers, mucoadhesive materials, carrier for the delivery of high molecular weight drugs, and gene-delivery.
Functional Foods
Functional Foods Presenting cutting-edge information on new and emerging food engineering processes, Functional Foods, the second volume in the groundbreaking new series, “Bioprocessing in Food Science,” is an essential reference on the modeling, quality, safety, and technologies associated with food processing operations today.
Frontiers of Fundamental Physics ; Proceedings of the Sixth International Symposium "Frontiers of Fundamental and Computational Physics", Udine, Italy, 26-29 September 2004
The Sixth International Symposium "Frontiers of Fundamental and Computational Physics", Udine, Italy, 26-29 September 2004, aimed at providing a platform for a wide range of physicists to meet and share thoughts on the latest trends in various, mainly cross-disciplinary research areas. This includes the exploration of frontier lines in High Energy Physics, Theoretical Physics, Gravitation and Cosmology, Astrophysics, Condensed Matter Physics, Fluid Mechanics. Such frontier lines were unified by the use of computers as an, often primary, research instruments, or dealing with issues related to information theory.
Frontiers in Anti-Infective Drug Discovery ; Vol.9
Covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs
From parity violation to hadronic structure and more : Refereed and selected contributions from Grenoble, France, June 8-11, 2004
Almost 50 years after the proposal of Lee and Young in 1956 to test the hypothesis of parity violation in weak interactions and the subsequent experimental verification of parity violation by C. S. Wu, parity violation has today become a useful property of weak interactions. This is due to the fact that the focus nowadays has changed: parity violation in weak interactions is no more a topic of investigation but is used as a tool in many different fields ranging from nuclear physics to the search for the hidden extra dimensions requested by string theory. For our first workshop which took place June 5-8, 2002, at the Institut fiir Ke- physik of the Johannes Gutenberg-Universitat Mainz, we concentrated on the in vestigation of the strangeness contribution in the nucleon. This book contains the refereed and selected papers of the second workshop "From Parity Violation to Hadron Structure and more (Part II)", which took place June 8-11, in the Labo- toire de Physique Subatomique et de Cosmologie, in Grenoble. These papers appear in EPJAdirect, the electronic-only part of EPJA, and they are accessible without restrictions. They will also appear in printed form and can be ordered through Springer. The excellent presentations show the dramatic and steady progress in the accuracy of measured parity violating asymmetries over the last few years.
From Nucleons to Nucleus : Concepts of Microscopic Nuclear Theory
From Nucleons to Nucleus deals with single-particle and collective features of spherical nuclei. Each nuclear model is introduced and derived in detail. The formalism is then applied to light and medium-heavy nuclei in worked-out examples, and finally the acquired skills are strengthened by a wide selection of exercises, many relating the models to experimental data.
Fractures du genou = Knee fractures
Provides a comprehensive yet practical overview of the management of knee fractures and their complications. The editorial team comprises specialists from France, Switzerland, Belgium, the United States, and Ireland, many of whom are members of the AO group. Imaging strategies, assessment, classification, and anatomical variations are reviewed for each anatomical location. All therapeutic approaches are discussed without exception: conventional implants, intramedullary nailing, minimally invasive techniques, including the role of external fixation, and newer technologies such as the LISS. These approaches are subjected to critical analysis to identify the best options based on the indications and individual circumstances. The patellar apparatus is addressed in its functional unity. Postoperative management, influenced by functional prognosis, is also covered, as is the management of malunion, stiffness, and other complications. Finally, very specific problems are discussed, such as pediatric injuries, patellectomies, periprosthetic fractures, often complex projectile injuries, the role of immediate arthroplasty and massive grafts, but also associated injuries which sometimes have a heavy impact on the final prognosis.
Foundation PHP5 for Flash
This latest, completely rewritten, edition again brings together three of the web's hottest technologies—Flash, the server-side language PHP, and the MySQL database system. We've brought things back up to date, using ActionScript 2.0, PHP 5.0, and MySQL 4.1, the book has been designed to be version-neutral. In other words, you can be confident that you're working with the latest standards, but that your applications won't break if deployed on an older server. The book also provides a brief introduction to an alternative database system, SQLite, which is now automatically bundled with PHP 5 and requires no installation.
Formulating poorly water soluble drugs
A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.
Formulas, ingredients and production of cosmetics technology of skin- and hair-care products in Japan
Provides the comprehensive knowledge and instruction necessary for researchers to design and create cosmetics products. The book’s chapters cover a comprehensive list of topics, which include, among others, the basics of cosmetics, such as the raw materials of cosmetics and their application; practical techniques and technologies for designing and manufacturing cosmetics, as well as theoretical knowledge; emulsification; sensory evaluations of cosmetic ingredients; and how to create products such as soap-based cleansers, shampoos, conditioners, creams, and others. The potential for innovation is great in Japan’s cosmetics industry. This book expresses the hope that the high level of dedicated research continues and proliferates, especially among those who are innovators at heart.
Formalizing Medieval Logical Theories : Suppositio, Consequentiae and Obligationes
This book presents novel formalizations of three of the most important medieval logical theories: supposition, consequence and obligations. In an additional fourth part, an in-depth analysis of the concept of formalization is presented – a crucial concept in the current logical panorama, which as such receives surprisingly little attention.
Food physics : Physical properties : Measurement and applications
Food Physics deals with the physical properties of food, food ingredients and their measurement. Physical properties of food play a key role in all fields where modern technological processes are applied for the generation of food raw materials and the production of food. The determination of physical properties of food and related products are a pre-requisite for planning, production engineering and automation processes in today’s food, pharmaceutical and cosmetics industries as well as in all related quality control activities.This book describes the principles of food physics starting with the very basics and focuses on the needs of practitioners without omitting important basic principles.
Food allergens : methods and protocols
Provides a comprehensive collection of methods and protocols in food allergy and food allergens studies. The selected protocols explore the study of food allergens, from recombinant production, purification procedures, IgE and T cell epitopes characterization, to allergen structure description, cellular responses, and tolerance induction, through a variety of techniques and animal models.
Food addiction
This approach acknowledges the apparent parallels between substance use disorders and overeating of highly palatable, high-caloric foods. Although this idea seems to be relatively new, research on food addiction actually encompasses several decades, a fact that often remains unrecognized. Scientific use of the term addiction in reference to chocolate even dates back to the 19th century. In the 20th century, food addiction research underwent several paradigm shifts, which include changing foci on anorexia nervosa, bulimia nervosa, obesity, or binge eating disorder. Thus, the purpose of this review is to describe the history and state of the art of food addiction research and to demonstrate its development and refinement of definitions and methodologies
FOBA : Buildings
The book also chronicles the FOB Homes systema FOBA subsidiary company established in 1999a uniquely creative response to the generic mass-produced pre-fabricated housing available in Japan. With five basic prototypes that can be easily adapted to any site or client, FOB Homes redefines the concept of standardized housing. Their simple, neutral white boxes counter the visual chaos of contemporary Japan and offer the elegance and experience of "architecture" to the general publica union of modernist aesthetics with the modernist ideology of democratic, affordable design.
Flow and microreactor technology in medicinal chemistry
The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort.
