الصفحة 132
الصفحة 132
Abeta Peptide and Alzheimers Disease : Celebrating a Century of Research
Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases.
Abductive Reasoning : Logical Investigations into Discovery and Explanation
Abductive Reasoning: Logical Investigations into Discovery and Explanation is a much awaited original contribution to the study of abductive reasoning, providing logical foundations and a rich sample of pertinent applications.
A window on the future of geodesy ; Proceedings of the International Association of Geodesy. IAG General Assembly, Sapporo, Japan June 30 - July 11, 2003
These proceedings represent the worldwide picture of the state of the art of geodesy. The volume comprehensively covers the most recent results and supplies a good review of the new ideas developing in the field, opening a window to the future of geodesy.
A Successful Transformation? : Restructuring of the Czech Automobile Industry
This book investigates the complex processes of the post-1990 transformation in the Czech automotive industry and its selective integration in the West European automobile manufacturing system. The post-1990 restructuring of the Czech automotive industry is analyzed in the context of its pre-1990 development and in the context of the Central and East European automobile industry as a whole. Specifically, the book examines the development and post-1990 restructuring of the Czech passenger car industry, the components industry and truck manufacturing. Major topics covered include the development of the Czech automotive industry before 1990, the detailed case study of Škoda Auto, the effects of the post-1990 privatization in the Czech automotive industry, the role and effects of foreign direct investment during the post-1990 restructuring, the restructuring of the Czech truck industry, and the rapid development of the automotive components manufacturing.
A Singular Introduction to Commutative Algebra
Aims to lead a further stage in the computational revolution in commutative algebra. Another feature of the book is its breadth of coverage of theoretical topics in the portions of commutative algebra closest to algebraic geometry, with algorithmic treatments of almost every topic.
A short guide to clinical pharmacokinetics
Consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics.
A Remarkable Collection of Babylonian Mathematical Texts : Manuscripts in the Schøyen Collection: Cuneiform Texts I
This new text from Jöran Friberg, the leading expert on Babylonian mathematics, presents 130 previously unpublished mathematical clay tablets from the Norwegian Schøyen collection, and provides a synthesis of the author's most important work. Through a close study of these tablets, Friberg has made numerous amazing discoveries, including the first known examples of pre-Classical labyrinths and mazes, a new understanding of the famous table text Plimpton 322, and new evidence of Babylonian familiarity with sophisticated mathematical ideas and objects, such as the three-dimensional Pythagorean equation and the icosahedron.
A Pan-Chromatic View of Clusters of Galaxies and the Large-Scale Structure
The reviews presented in this volume cover a wide-range of cluster of galaxies topics like the physics of the ICM gas, the internal cluster dynamics, the detection of clusters using different observational techniques, the great advances in analytical or numerical modeling of clusters, weak and strong lensing effects, the large scale structure as traced by clusters, the cosmological significance of clusters as well as the formation and evolution of clusters within the new cosmological paradigm.
A New Foundation of Physical Theories
Written in the tradition of G. Ludwig’s groundbreaking works, this book aims to clarify and formulate more precisely the fundamental ideas of physical theories. By introducing a basic descriptive language of simple form, in which it is possible to formulate recorded facts, ambiguities of physical theories are avoided as much as possible. In this approach the field of physics that should be described by a theory is determined by basic concepts only, i.e. concepts that can be explained without a theory.In this context the authors introduce a new concept of idealization and review the process of discovering new concepts. They believe that, when the theories are formulated within an axiomatic basis, solutions can be found to many difficult problems such as the interpretation of physical theories, the relations between theories as well as the introduction of physical concepts.
A Modern Introduction to Probability and Statistics : Understanding Why and How
A Modern Introduction to Probability and Statistics has numerous quick exercises to give direct feedback to the students. In addition the book contains over 350 exercises, half of which have answers, of which half have full solutions. A website at www.springeronline.com/1-85233-896-2 gives access to the data files used in the text, and, for instructors, the remaining solutions. The only pre-requisite for the book is a first course in calculus; the text covers standard statistics and probability material, and develops beyond traditional parametric models to the Poisson process, and on to useful modern methods such as the bootstrap.
A History of Plastic Surgery
Te frst section deals with anatomy and the healing of wounds, discusses You have in your hands a work that should become a old and new plastic surgical procedures, and outlines the milestone of our understanding of medical history. In it history of anaesthesia. Te second covers the methods Professor Paolo Santoni-Rugiu and Mr Philip Sykes trace used from ancient times to reconstruct various areas of the development of plastic surgery and much of medi- the body and is the most extensive. Te last section d- cine in general, over three millennia. With his extensive cusses the history of cosmetic surgery and the origin of knowledge of clinical plastic surgery, no one could be present day procedures. better placed than the senior author to gather this valu- Te pages ring with the names of giants of the medical able material from historical documents.
A History of Interior Design ; 4th Ed
Exploring a broad range of design styles and movements, this revised and expanded edition includes coverage of non-Western design and vernacular interior architecture and features 665 photographs and drawings (color and black-and-white). The companion image bank includes an interactive presentation of periods and styles, incorporating more than 100 illustrations.
A handful of happiness herbs
Depression is a multifactorial disorder that affects millions of people worldwide, and none of the currently available therapeutics can completely cure it. Thus, there is a need for developing novel, potent, and safer agents. Recent medicinal chemistry findings on the structure and function of the serotonin 2A (5-HT2A) receptor facilitated design and discovery of novel compounds with antidepressant action. The consumption of cocoa-based products rich in bioactive compounds can be related to decreased risk in coronary heart problems, hypertension, diabetes, and depression...
A Guide to Methods in the Biomedical Sciences
A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research. This is not intended to be a methods book. Rather, it is intended to be a book that outlines the purpose of the methods described, their limitations and provide alternative approaches as appropriate. Thousands of methods have been developed in the various biomedical disciplines and those covered in this book represent the basic, essential and most widely used methods in several different disciplines. The historical background (including some interesting anecdotes) leading to the development of ground-breaking techniques are described, especially those that significantly advanced the field of biomedical research. Advances that earned their inventors prestigious Nobel Prizes are emphasized. The book is divided into six sections, highlighting selected methods in protein chemistry, nucleic acids, recombinant DNA technology (including forensic based methods), antibody-based techniques, microscopy and imaging, and the use of animals in biomedical sciences.
A Guide to Graph Algorithms
Offers high-quality content in the research area of graph algorithms and explores the latest developments in graph algorithmics. The reader will gain a comprehensive understanding of how to use algorithms to explore graphs. It is a collection of texts that have proved to be trend setters and good examples of that. The book aims at providing the reader with a deep understanding of the structural properties of graphs that are useful for the design of efficient algorithms. These algorithms have applications in finite state machine modelling, social network theory, biology, and mathematics. The book contains many exercises, some up at present-day research-level. The exercises encourage the reader to discover new techniques by putting things in a clear perspective.
A guide to dental sedation
This concise guide bridges the gap between classroom instruction and the actual application of various methods of sedation. The considerations for each dental specialty are covered, with special focus on pediatric and special needs patients. Chapters summarize the medications used in sedation, including dosages, warnings, and reversal agents, and sections on nitrous oxide discuss how to administer it without harm to the provider.
A Geometry of Approximation : Rough Set Theory: Logic, Algebra and Topology of Conceptual Patterns
A Geometry of Approximation' addresses Rough Set Theory, a field of interdisciplinary research first proposed by Zdzislaw Pawlak in 1982, and focuses mainly on its logic-algebraic interpretation. The theory is embedded in a broader perspective that includes logical and mathematical methodologies pertaining to the theory, as well as related epistemological issues. Any mathematical technique that is introduced in the book is preceded by logical and epistemological explanations. Intuitive justifications are also provided, insofar as possible, so that the general perspective is not lost.
A First Course in Statistical Inference
Offers a modern and accessible introduction to Statistical Inference, the science of inferring key information from data. Aimed at beginning undergraduate students in mathematics, it presents the concepts underpinning frequentist statistical theory. Written in a conversational and informal style, this concise text concentrates on ideas and concepts, with key theorems stated and proved. Detailed worked examples are included and each chapter ends with a set of exercises, with full solutions given at the back of the book. Examples using R are provided throughout the book, with a brief guide to the software included. Topics covered in the book include: sampling distributions, properties of estimators, confidence intervals, hypothesis testing, ANOVA, and fitting a straight line to paired data.
A First Course in Modular Forms
This book introduces the theory of modular forms with an eye toward the Modularity Theorem: All rational elliptic curves arise from modular forms. The topics covered include: • elliptic curves as complex tori and as algebraic curves, • modular curves as Riemann surfaces and as algebraic curves, • Hecke operators and Atkin–Lehner theory, • Hecke eigenforms and their arithmetic properties, • the Jacobians of modular curves and the Abelian varieties associated to Hecke eigenforms, • elliptic and modular curves modulo p and the Eichler–Shimura Relation, • the Galois representations associated to elliptic curves and to Hecke eigenforms. As it presents these ideas, the book states the Modularity Theorem in various forms, relating them to each other and touching on their applications to number theory.
A First Course in Differential Equations
This text is designed for the standard post-calculus course in elementary differential equations. It is a brief, one-semester treatment of the basic ideas, models, and solution methods. The book, which serves as an alternative to existing texts for instructors who want more concise coverage, emphasizes graphical, analytical, and numerical approaches, and is written with clear language in a user-friendly format. It provides students with the tools to continue on to the next level in applying differential equations to problems in engineering, science, and applied mathematics.
