الصفحة 13
الصفحة 13
Mechanisms of Lymphocyte Activation and Immune Regulation XI ; B Cell Biology
These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.
Mechanisms of Lymphocyte Activation and Immune Regulation X ; Innate Immunity
Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Mechanisms of Insulin Action
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.
Mechanisms of Angiogenesis
Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.
Mechanics of Microelectromechanical Systems
This book offers a comprehensive coverage to the mechanics of microelectromechanical systems (MEMS), which are analyzed from a mechanical engineer’s viewpointelectric energy.
Mechanics and Physics of Fracture : Multiscale Modeling of the Failure Behavior of Solids
Provides a comprehensive understanding of the macroscopic failure behavior of solids from the description of the microscopic failure processes and their coupling with the microstructure. Several fundamental questions were addressed: the relation between the microstructural features of materials and their fracture properties and crack trajectories; the role of damage mechanisms and non-linear deformations near the crack tip on the failure behavior of solids; and finally the role of dynamic inertial effects during fast fracture was more briefly evoked.
Meat Biotechnology
The main goal of this book is to provide the reader with the recent developments in biotechnology and their applications in the meat processing chain. To achieve this goal, the book is divided into four parts. The first part deals with the use of modern biotechnology applied to farm animals. The second part focuses on the recent biotechnological developments in starter cultures for better meat fermentation. The third part discusses current approaches to improve the quality and nutritional properties of meats. The final part presents the latest advances in protection against foodborne pathogens, and other recent trends in the field. Written by distinguished international contributors, this book brings together the advances in such varied and different biotechnological topics
Means, Ends and Medical Care
In this remarkable book, Gary Wright brings his thirty years of experience as a physician in pediatric and family medicine together with his Ph.D. in philosophy to address the important problem of the nature of good medical reasoning. Wright gives a brilliant analysis of the complex internal structure of our concepts of health and disease, showing that our present models are wholly incapable of dealing with the realities of actual human disease. He then shows the error of assuming that we always know in advance what the medical and moral ends are for any medical situation. This leads to a radical questioning of so-called "rational actor" or "economic" models of rationality that are popular in medicine today.
Meaning in Action : Constructions, Narratives, and Representations
are far from genetically ? xing what behavioral preferences they may possess. Instead, learning mechanisms offer a ? exible way of attaining locally important cultural knowledge within temporal windows of opportunity as has been convi- ingly shown by research in language and culture attainment. Similar mechanisms are likely to exist for other social capacities, such as mate preferences, for example. It is this role of our biological inheritance that social science must appreciate in order to furnish a more complete understanding of human behavior. Within the natural range of variation of capacities and armed with biologically conditioned learning mechanisms we live out lives of meaning – in which we hold some things to be real, rational, valuable or morally right, and others not. It is this world of meaning in which we ? nd love and hate, struggles for justice, power, and money, and the dramas that lend to life both its depth and passion.
MDCT : A Practical Approach
Computed tomography (CT) is the most rapidly evolving medical imaging technology. This book describes current examination techniques and advanced clinical applications of state-of-the-art multidetector computed tomography (MDCT) scanners in chapters contributed by several distinguished radiologists and clinicians. Each chapter is written from a practical perspective so that radiologists, residents, medical physicists, and radiology technologists can obtain relevant information about MDCT applications in neuroradiology, cardiac imaging, chest, abdominal, and musculoskeletal radiology subspecialties. Each coauthor provides pertinent illustrations and tables for better understanding of current and advanced applications of MDCT scanners. Readers will benefit from the experience these authors describe in chapters on MDCT technology, contrast administration techniques, contrast adverse effects and their management, and advanced applications of MDCT.
Mathematics Education in Different Cultural Traditions- A Comparative Study of East Asia and the West : The 13th ICMI Study
The volume covers a very wide field including the contexts of mathematics education, the curriculum, teaching and learning, and teachers’ values and beliefs. Within these broad parameters some of the particular cross-cultural issues that are discussed include intuition and logical reasoning, influences of Confucianism and Ancient Greek traditions, basic skills and process abilities, learners’ perspectives, assessment practices, text books and ICT multimedia.
Isomorphisms Between H¹ Spaces
Presents a thorough and self-contained presentation of H¹ and its known isomorphic invariants, such as the uniform approximation property, the dimension conjecture, and dichotomies for the complemented subspaces. The necessary background is developed from scratch. This includes a detailed discussion of the Haar system, together with the operators that can be built from it (averaging projections, rearrangement operators, paraproducts, Calderon-Zygmund singular integrals). Complete proofs are given for the classical martingale inequalities of C. Fefferman, Burkholder, and Khinchine-Kahane, and for large deviation inequalities. Complex interpolation, analytic families of operators, and the Calderon product of Banach lattices are treated in the context of H^p spaces. Througout the book, special attention is given to the combinatorial methods developed in the field, particularly J. Bourgain's proof of the dimension conjecture, L. Carleson's biorthogonal system in H¹, T. Figiel's integral representation, W.B. Johnson's factorization of operators, B. Maurey's isomorphism, and P. Jones' proof of the uniform approximation property. An entire chapter is devoted to the study of combinatorics of colored dyadic intervals."
Iron Nutrition in Plants and Rhizospheric Microorganisms
This book uses an interdisciplinary approach to provide a comprehensive review on the status of iron nutrition in plants. International scientists discuss research on acquisition of iron by strategy I and strategy II plants. These reviews summarize a variety of plant species and include both laboratory and field observations. Topics covered in this book include: plants as a source of iron for animals and humans, iron translocation in the plants, iron-stimulated activities that influence crop yield and fruit tree productivity, iron uptake by plants as influenced by microorganisms (i.e. free living soil microorganisms, symbiotic nitrogen-fixing and pathogenic bacteria), the role of plant hormones in iron transport, iron-metal competition in phytoremediation, root zone activities involving interactions between minerals and organic matter, the role of microbial siderophores in rhizospheric iron cycling, iron storage as phytoferritin, proteomic and metabolic studies associated with iron stress response, methods for studying iron metabolism including stable isotopes, and the correction of iron deficiency through the use of synthetic or natural chelates.
Iron metabolism : Methods and protocols
Explores classical and cutting-edge methods optimized and validated to analyze various aspects of iron metabolism, from in vitro to multi-organ level. Opening with a section on basic iron metabolism methods, the book continues with methods applicable to a variety of systems, ranging from bacteria to cultured mammalian cells and tissues, with a focus on cellular heme and iron-sulfur cluster species, as well as mitochondrial iron and its derivatives. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
IQ Calibration Techniques for CMOS Radio Tranceivers
There are a lot of factors that degrade the matching of gains and phases between I/Q signals: the instinct layout mismatch, the random mismatch of the devices, the different temperatures over the I/Q signal paths. IQ Calibration Techniques For CMOS Radio Transceivers describes a fully-analog compensation technique without baseband circuitry to control the calibration process. This book will use an 802.11g transceiver design as an example to give a detailed description on the I/Q gains and phases imbalance auto-calibration mechanism.
Ionospheric Precursors of Earthquakes
Changes included changing my career from the field of space plasma physics to Earth sciences and geophysics, and changes in my personal life giving me h- piness and compliance in my present family.
Io After Galileo : A New View of Jupiter’s Volcanic Moon
A New View of Jupiter’s Volcanic Moon is the first book dedicated to this unique satellite, and it does justice to Io’s dubious charms.a thoughtful collection of articles ranging from the history of Io exploration through the satellite’s remarkable and hostile surface geology to its interaction with the harsh Jovian environment.
Investor-State Dispute Settlement and National Courts : Current Framework and Reform Options
This book examines the multiple intersections between national and international courts in the field of investment protection, and suggests possible modes for regulating future jurisdictional interactions between domestic courts and international tribunals.
Investment Management and Mismanagement : History, Findings, and Analysis
These issues include performance, anomalies, market timing, suitability, and churning, among others. The construct of mismanagement is presented in light of the impact of various costs on investment returns.
Investigating the Body in the Victorian Asylum : Doctors, Patients, and Practices
This book explores how the body was investigated in the late nineteenth-century asylum in Britain. As more and more Victorian asylum doctors looked to the bodily fabric to reveal the ‘truth’ of mental disease, a whole host of techniques and technologies were brought to bear upon the patient's body. These practices encompassed the clinical and the pathological, from testing the patient's reflexes to dissecting the brain.
