الصفحة 126
الصفحة 126
Biochemistry and molecular biology of antimicrobial drug action
This stimulating new edition of the well-respected title Biochemistry and Molecular Biology of Antimicrobial Drug Action primarily covers medically important antimicrobial agents, but also includes some compounds not in current medical use which have been invaluable as research tools in biochemistry.
Biochemistry and cell biology of ageing ; Part III : Biomedical science
Covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Bio-based Building Skin
This book provides a compendium of material properties, demonstrates several successful examples of bio-based materials’ application in building facades, and offers ideas for new designs and novel solutions. It features a state-of-the-art review, addresses the latest trends in material selection, assembling systems, and innovative functions of facades in detail. Selected case studies on buildings from diverse locations are subsequently presented to demonstrate the successful implementation of various biomaterial solutions, which defines unique architectural styles and building functions. The structures, morphologies and aesthetic impressions related to bio-based building facades are discussed from the perspective of art and innovation; essential factors influencing the performance of materials with respect to functionality and safety are also presented. Special emphasis is placed on assessing the performance of a given facade throughout the service life of a building, and after its end.
Bioanalytical aspects in biological therapeutics
The book discusses the challenges and considerations for bioanalytical support, covering a wide range of central topics in the field, including overview and basic immunology for testing of biological therapeutics, pharmacokinetic aspects, clinical immunogenicity prediction and testing, biomarker testing, biotransformation assessment for biologics, statistical aspects of bioanalytical testing, regulatory expectations, and more
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocycles V
This volume contains 10 chapters. The contributions are from researchers famous in their respective fields and the chapters contain high quality reviews on topics related to the chemo-biological studies of several different heterocyclic groups. The first chapter from Saracoglu reviews the functionalization of indoles and the pyrroles via Michael additions, as these compounds have potential for their biological activities. In second chapter Men ́endez reviews the chemistry of the welwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis and recent strategies for the synthesis of lignans.
Bioactive Heterocycles IV
This volume contains nine more contributions from expert researchers of the?eld, providing readers with in depth and current research results regarding therespective topics. In the?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in clinicaltrials. In the third chapter, Khan reviews some aspects of molecular modeling studies on biologically active alkaloids.
Bioactive Heterocycles III
Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, and providein sight in the new themesofnaturalproduct research.Manyofthe contributors illustrate their laboratory experiences. It's obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological activities of artemisinin, one of the most promising antimalarial molecules, and its related natural peroxides.
Bioactive Conformation I
This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts – it is still valid and useful after 5 or 10 years. More information as well as the electronic version of the whole content available at: springerlink.com. The book will appeal to scientists and practitioners in the mentioned fields and in industry.
Bioactive Confirmation II
Specific binding of a ligand to a receptor is a key step in a variety of biol- ical processes, such as immune reactions, enzyme cascades, or intracellular transport processes. The ligand-receptor terminology implies that the rec- tor molecule is signi?cantly larger than the ligand, and the term "bioactive conformation" usually characterizes the conformation of a ligand when it is bound to a receptor. In a more general sense, bioactive conformation applies toanymoleculeinabiologicallyrelevantboundstateregardlessofsizecons- erations. Mostofthecontributions tothisbookaddressligandsthat aremuch smaller than their receptors. X-ray crystallography and high resolution NMR spectroscopy are the two main experimental techniques used to study bioactive conformations. The- fore, the twovolumes ofthisbookcover approachesthat use either ofthetwo techniques, or a combination thereof.
Bioactive components of milk
Of all food products dairy foods have the most potential concerning functional foods. Therefore, there is a tremendous amount of interest in value-added milk products and the identification of components in food which have health benefits. Bioactive Components of Milk provides an overview of these derived components and their diverse activities including: the stimulation of beneficial microflora, alerting the immune system to the presence of potential pathogens and allergens, binding and eliminating toxins, etc. The book is divided into four parts. The first part focuses on bioactive milk lipid components, which very widely among mammalian species. The second part describes different aspects of biological active colostrums and milk proteins and their derivatives, with special concern on species specific effects. The third part reviews the production of recombinant human proteins in the milk of livestock animals - including ethical issues - and the aims of altering milk composition for the benefit of both the animals themselves and the consumers. The final part focuses on the influence of ruminants nutrition on the biological activity of milk.
Big Data in Context : Legal, Social and Technological Insights
Sheds new light on a selection of big data scenarios from an interdisciplinary perspective. It features legal, sociological and economic approaches to fundamental big data topics such as privacy, data quality and the ECJ’s Safe Harbor decision on the one hand, and practical applications such as smart cars, wearables and web tracking on the other. Addressing the interests of researchers and practitioners alike, it provides a comprehensive overview of and introduction to the emerging challenges regarding big data.All contributions are based on papers submitted in connection with ABIDA (Assessing Big Data), an interdisciplinary research project exploring the societal aspects of big data and funded by the German Federal Ministry of Education and Research.
Big Data and Global Trade Law
Explores the relevance of global trade law for data, big data and cross-border data flows. Contributing authors from different disciplines including law, economics and political science analyze developments at the World Trade Organization and in preferential trade venues by asking what future-oriented models for data governance are available and viable in the area of trade law and policy. The collection paints the broad picture of the interaction between digital technologies and trade regulation as well as provides in-depth analyses of critical to the data-driven economy issues, such as privacy and AI, and different countries' perspectives.
Big data analytics and machine intelligence in biomedical and health informatics : Concepts, methodologies, tools and applications
Provides coverage of developments and state-of-the-art methods in the broad and diversified data analytics field and applicable areas such as big data analytics, data mining, and machine intelligence in biomedical and health informatics. Covers the latest advances and developments in health informatics, data mining, machine learning, and artificial intelligence. They have been organized with respect to the similarity of topics addressed, ranging from issues pertaining to the Internet of Things (IoT) for biomedical engineering and health informatics, computational intelligence for medical data processing, and Internet of Medical Things??(IoMT).
Beyond Kyoto : A new global climate certificate system : Continuing Kyoto commitsments or a global ´Cap and Trade´ scheme for a sustainable climate policy?
This book shows how humankind can ‘prevent dangerous interference with the c- mate system’ without dangerous interference with the global economic system. In the two underlying studies on behalf of the Ministry of Environment and Transport of i the German federal state of Baden-Württemberg, the results have been elaborated through scientific evaluation of different climate protection systems and intensive developmental work on an efficient climate protection system. The results will be presented in nine chapters according to the following nine basic R&D steps: 1. Quantifying the ‘ultimate climate objective’ of the world community in order ‘to prevent dangerous interference with the climate system,’ thus achieving climate sustainability; 2. Development of a comprehensive standard system for evaluating the prospect of success for different climate protection systems; 3. Based on this scientific standard system, evaluation of the current Kyoto system and of the most important proposals for ‘incremental regime evolution’ of the Kyoto system. Unfortunately, it must be noted that these systems are incapable of achi- ing climate sustainability; 4. Evaluating three proposals for ‘structural regime change’ of the Kyoto system. Following this objective evaluation process and numeric comparison of the diff- ent proposals, 5. Description of the eight basic elements of GCCS and its in-depth ‘critical asse- ment;’ 6.
Between Necessity and Probability : Searching for the Definition and Origin of Life
This study investigates the major theories of the origins of life in light of modern research with the aim of distinguishing between the necessary and the optional and between deterministic and random influences in the emergence of what we call ‘life.’ Life is treated as a cosmic phenomenon whose emergence and driving force should be viewed independently from its Earth-bound natural history. The author synthesizes all the fundamental life-related developments in a comprehensive scenario, and makes the argument that understanding life in its broadest context requires a material-independent perspective that identifies its essential fingerprints.
Between Mobility and Migration : The Multi-Level Governance of Intra-European Movement
Offers a critical perspective on intra-European mobility and migration by using new empirical data and theoretical discussions. It develops a theoretical and empirical analysis of the consequences of intra-European movement for sending and receiving urban regions in The Netherlands, Sweden, Austria, Turkey, Poland and Czech Republic.The book conceptualizes Central and Eastern European (CEE) migration by distinguishing between different types of CEE migrants and consequences. This involves a mapping of migration corridors within Europe, a unique empirical analysis of consequences for urban regions, and an analysis of governance responses. Next to the European and country perspectives on this phenomenon, the book focuses on the local perspective of urban regions where most mobile citizens settle (either permanently or temporarily). This way the book puts the analysis of intra-European movement in the perspective of broader theoretical debates in migration studies and beyond.
Between dirt and discussion : Methods, methodology and interpretation in historical archaeology
The cases presented in this volume revisit old methods and previous scholarly approaches with new perspectives, along with incorporating the newest technologies available to understanding the past.
Behavioral finance and your portfolio : A navigation guide for building wealth
Designed for investors who are serious about maximizing their gains, in this book you’ll discover how to: ● Take control of your decision-making—even when challenging markets push greed and fear to intolerable levels ● Reflect on how to make investment decisions using data-backed and substantiated information instead of emotion and bias ● Counter deep-seated biases like loss aversion, hindsight and overconfidence with self-awareness and hard facts ● Identify your personal investment psychology profile, which you can use to inform your future financial decision making
Beginning Google Maps Applications with Rails and Ajax : From novice to professional
Beginning Google Maps Applications with Rails and Ajax: From Novice to Professional is the first book to comprehensively introduce the service from a developer perspective, showing you how you can integrate mapping features into your Rails-driven web applications. Proceeding far beyond simplistic map display, youll learn how to draw from a variety of data sources.
