الصفحة 111
الصفحة 111
An introduction to bioanalysis of biopharmaceuticals
Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.
An Introduction to Bayesian Analysis : Theory and Methods
This book is a contemporary introduction to theory, methods and computation in Bayesian Analysis. It focuses on topics that have stood the test of time and on emerging areas. No other such book is available in the market.
An Interactive Multimedia Introduction to Signal Processing
A didactic concept is undertaken for microelectronics, computer technology and communication engineering, which deals with the visualization of signals and processes in addition to graphical programming of signal processing systems. Through the utilization of a professional and globally supported software for metrology and control engineering, DasyLab, useful applications can be developed, modified and optimized. Computer supported processing of real signals is made possible over the sound card and the parallel port. Over two hundred pre-programmed signal engineering systems and design transparencies are provided. Pictures also play a dominant rule in this book: there are numerous introduction-videos, one for every chapter, more than 250 high-quality pictures and - most important – all the "living" experiments and their results are visualized. With this learning system, readers can now make use of "equipment" and software, which was practically unaffordable for individuals in the past. What's more, here is a very new concept for learning Signal Processing, not only from the physically-based scientific fundamentals, but also from the didactic perspective, based on modern results of brain research.
An Integrated Approach to Software Engineering
An Integrated Approach to Software Engineering introduces software engineering to advanced-level undergraduate and graduate students of computer science. It emphasizes a case-study approach whereby a project is developed through the course of the book, illustrating the different activities of software development. The sequence of chapters is essentially the same as the sequence of activities performed during a typical software project. All activities, including quality assurance and control activities, are described in each chapter as integral activities for that phase of development. Similarly, the author carefully introduces appropriate metrics for controlling and assessing the software process. Chapters in this revised edition, updated for today’s standards, include these new features: Software Process, Requirements Analysis and Specification, Software Architecture, Project Planning, Object Oriented Design, Coding,Testing,
An Energy Analysis of Household Consumption : Changing Patterns of Direct and Indirect Use in India
The book presents a novel socio-economic approach to analysing the - ergy system and energy consumption in India from a household persp- tive. In doing so, it views households as the ultimate end-consumers and estimates and analyses the direct and indirect energy requirements of household consumption, both at an aggregate national level as well as at a disaggregate household level. In addition, the work incorporates two c- cial aspects often ignored by many energy studies that are characteristic of most developing countries, namely the importance of non-commercial sources of biomass energy in the energy systems of these countries, and the enormous diversity and inequity in the patterns of energy access and use across households with different lifestyles and levels of well being.
An economic feasibility study of extracting electrical energy from solar panels
The research is a case that study depends on both secondary and primary data. Secondary data should be collected from the firms producing the photo panels(local and foreign) and those that working in this field in addition to the data of the ministry of electricity in Syria and the national center of power, while primary data should be collected by interviews with the persons working in electricity field .Then the traditional steps of commercial profitability analysis should be followed starting in pre-feasibility study passing the detailed feasibility study steps which, in turn, consists of the following phases : market study , technical study , financial study in order to reach the estimated net cash flows that should be used in analyzing the project feasibility depending on all criteria both traditional " payback-period . Simple rate of return" and economic criteria " net present value and the internal rate of return”.
An assessment framework for compliance with international space law and norms : Promoting equitable access and Use of space for emerging actors
proposes a framework for assessing countries’ levels of compliance with international space law and norms. It begins by exploring the development of two movements – the evidence-based policymaking and programming movement, and the rise of ratings and rankings research – and their growth across various disciplines. The analysis suggests that such efforts are useful in gauging the behavior of countries in space according to how well they adhere to existing space law and norms. To date, there is no comprehensive, periodic, and systematic measure of countries’ efforts to comply with space law and norms; this work endeavors to fill that gap by offering a framework in which to assess compliance.
Ambiguities in Decision-oriented Life Cycle Inventories: The Role of Mental Models and Values
Shows for the first time how mental models and values influence this attribution in the life cycle inventory step of LCA. One of the key findings is that the different management rules for a sustainable use of materials must be taken into account for the attribution of material and energy flows to a product. Otherwise, improvement options recommended by an LCA might turn out to even worsen the environmental situation if reassessed from a meta-perspective. As a consequence of this book, the claim of unambiguitiy (‘objectivity’) of the life cycle inventory must be abandoned. A group-model building process for LCA is developed that allows one to grasp the decision makers' mental models and values in the inventory analysis on a case- and situation-specific basis. Only by this, LCA results will become relevant in a decision-making process. Two case studies on the modelling of recycling and other end-of-life options of aluminium windows and beech wood railway sleepers in LCA complement the methodological part.
Amartya Sens Capability Approach: Theoretical Insights and Empirical Applications
Kuklys examines how Nobel Prize-winning economist Amartya Sen’s approach to welfare measurement can be put in practice for poverty and inequality measurement in affluent societies such as the UK. Sen argues that an individual’s welfare should not be measured in terms of her income, but in terms what she can actually do or be, her capabilities. In Chapters 1 and 2, Kuklys describes the capability approach from a standard welfare economic point of view and provides a comprehensive literature review of the empirical applications in this area of research. In the remaining chapters, novel econometric techniques are employed to operationalise the concepts of functionings and capability to investigate inequality and poverty in terms of capability in the UK. Kuklys finds that capability measurement is always a useful complement to traditional monetary analysis, and particularly so in the case of capability-deprived disabled individuals.
Alternatives Considered But Not Disclosed : The Ambiguous Role of PowerPoint in Cross-Project Learning
This study investigates the role of PowerPoint in organizational communication, particularly in terms of a functional dilemma between its application for documentation as opposed to presentation purposes. The theoretical part of the analysis combines insights from both organizational communication studies (J. R. Taylor et al.) and social systems theory (N. Luhmann et al.). The empirical analysis shows that PowerPoint documents created for cross-project learning purposes contribute to an invisibilization rather than a visibilization of decision processes and their contingency.
Alternative pseudodifferential analysis : With an application to modular forms
This volume introduces an entirely new pseudodifferential analysis on the line, the opposition of which to the usual (Weyl-type) analysis can be said to reflect that, in representation theory, between the representations from the discrete and from the (full, non-unitary) series, or that between modular forms of the holomorphic and substitute for the usual Moyal-type brackets. This pseudodifferential analysis relies on the one-dimensional case of the recently introduced anaplectic representation and analysis, a competitor of the metaplectic representation and usual analysis.
Alternative Education : Global Perspectives Relevant to the Asia-Pacific Region
Alternative streams of education have been and remain an important but difficult theme for teachers, parents, policy-makers, and scholars. By focusing on case studies of six countries (Bolivia, Thailand, Australia, USA, The Netherlands, and Denmark), and by comprehensively analysing these by means of international comparative methodologies, the author approaches the nuts and bolts issues of alternative and mainstream education systems. The case studies include Charter Schools in the USA and Waldorf Schools in Australia. The study presents not only an insightful analysis of alternative forms of education with regard to actual issues in societies and also legal and administrative features of education. It provides insights into the kind of school development that could be appropriate in the 21st century and the types of educational communities we should seek to create in the age of globalisation.
Alternative breast imaging : Four model-based approaches
Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible. Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS).
Alpine Industrial Landscapes : Towards a New Approach for Brownfield Redevelopment in Mountain Regions
This book presents a pioneering research on brownfield redevelopment in mountain regions, and specifically in the European Alps. The origins and causes, the actual conditions as well as the future challenges and potentials of mountain brownfields are investigated from an interdisciplinary yet landscape-centered perspective. Through the reasoned combination of research-by-design methods and case-study analysis, the book explores the infrastructural relevance of these sites for the specific mountain territory, while advancing an innovative structuralist-systemic approach for their physical and functional transformation. The book includes, among others, a first transnational geo-mapping of Alpine brownfields, whose impressive outcomes in terms of site numbers and distribution can only confirm the urgency of this research.
Algorithms on Trees and Graphs : With Python Code
Introduces graph algorithms on an intuitive basis followed by a detailed exposition using structured pseudocode, with correctness proofs as well as worst-case analyses. Centered around the fundamental issue of graph isomorphism, the content goes beyond classical graph problems of shortest paths, spanning trees, flows in networks, and matchings in bipartite graphs. Advanced algorithmic results and techniques of practical relevance are presented in a coherent and consolidated way. Numerous illustrations, examples, problems, exercises, and a comprehensive bibliography support students and professionals in using the book as a text and source of reference. Furthermore, Python code for all algorithms presented is given in an appendix. Topics and features: Algorithms are first presented on an intuitive basis, followed by a detailed exposition using structured pseudocode / Correctness proofs are given, together with a worst-case analysis of the algorithms / Full implementation of all the algorithms in Python / An extensive chapter is devoted to the algorithmic techniques used in the book / Solutions to all the problems
Algorithms in Bioinformatics ; Vol.4175 : 6th International Workshop, WABI 2006, Zurich, Switzerland, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the 6th International Workshop on Algorithms in Bioinformatics, WABI 2006, held in Zurich, Switzerland in September 2006 in the course of the ALGO 2006 conference meetings. The 36 revised full papers presented were carefully reviewed and selected from 100 submissions. All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. For the first time also machine-learning approaches along with combinatorial optimization are covered.
Algorithms in Bioinformatics ; Vol. 3692 ; 5th international workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005, Proceedings
this book present the proceedings of the 5th Workshop on Algorithmsin Bioinformatics (WABI 2005) which took place in Spain, 2005. The Workshop on Algorithms in Bioinformatics highlights research workspecifically developed to address algorithmic problems in biosequence analysis. The emphasis is therefore on statistical and probabilistic algorithms that addressimportant problems in the field of molecular and structural biology. the workshop aims to present recent research results, includingsignificant work in progress, and to identify and explore directions of futureresearch.Original research papers (including significant work in progress) or state-of-the-art surveys were solicited on all aspects of algorithms in bioinformatics,including, but not limited to: exact and approximate algorithms for genomics,genetics, sequence analysis, gene and signal recognition, alignment, molecularevolution, phylogenetics, structure determination or prediction, gene expressionand gene networks, proteomics, functional genomics, and drug design.
Algorithms in Bioinformatics ; 8th International Workshop, WABI 2008, Karlsruhe, Germany, September 15-19, 2008. Proceedings
This book constitutes the refereed proceedings of the 8th International Workshop on Algorithms in Bioinformatics, WABI 2008, held in Karlsruhe, Germany, in September 2008 as part of the ALGO 2008 meeting.
Algorithms in Bioinformatics ; 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007, Proceedings
All current issues of algorithms in bioinformatics are addressed, ranging from mathematical tools to experimental studies of approximation algorithms and reports on significant computational analyses. Numerous biological problems are dealt with, including genetic mapping, sequence alignment and sequence analysis, phylogeny, comparative genomics, and protein structure. Furthermore the papers feature high-performance computing approaches to computationally hard learning and optimization problems in bioinformatics and cover methods, software and dataset repositories for development and testing of such algorithms and their underlying models.
Algorithms in Bioinformatics : Theory and Implementation
Explores a comprehensive and insightful treatment of the practical application of bioinformatic algorithms in a variety of fields. Delivers a fulsome treatment of some of the main algorithms used to explain biological functions and relationships. It introduces readers to the art of algorithms in a practical manner which is linked with biological theory and interpretation. The book covers many key areas of bioinformatics, including global and local sequence alignment, forced alignment, detection of motifs, Sequence logos, Markov chains or information entropy. Other novel approaches are also described, such as Self-Sequence alignment, Objective Digital Stains (ODSs) or Spectral Forecast and the Discrete Probability Detector (DPD) algorithm. Readers will also benefit from the inclusion of: A detailed presentation of new methods, such as Self-sequence alignment, Objective Digital Stains and Spectral Forecast ; A treatment of sequence alignment, including local sequence alignment, global sequence alignment and forced sequence alignment with full implementations ; Discussions of position-specific weight matrices, including the count, weight, relative frequencies, and log-likelihoods matrices ; A detailed presentation of the methods related to Markov Chains as well as a description of their implementation in Bioinformatics and adjacent fields ; An examination of information and entropy, including sequence logos and explanations related to their meaning ; A chapter on philosophical transactions that allows the reader a broader view of the prediction process ; Extensive worked examples with detailed case studies that point out the meaning of different results
