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الصفحة 11
الصفحة 11
Bacterial Physiology : A Molecular Approach
The application of new molecular methodologies in the study of bacterial behaviour and cell architecture has enabled new revolutionary insights and discoveries in these areas. While this has also raised a number of scientific mysteries about bacteria, it certainly improved our understanding of these organisms as complex and adaptive entities rather than just simple tiny buckets of enzymes. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology, but it also extends to biotechnology and drug-discovery disciplines where understanding cell behaviour and structure is essential for better exploitation of useful bacteria and effective eradication of harmful ones. This makes a new text accommodating recent developments in bacterial physiology highly relevant to a wide range of readership including those interested in basic and applied knowledge.
Bacterial Fish Pathogens : Disease of Farmed and Wild Fish
This completely revised and updated edition of Bacterial Fish Pathogens is a comprehensive discussion of the biological aspects of the bacterial taxa which cause disease in fish. Since the 3rd edition was published in 1999, much has changed in the control of disease of farmes and wild fish. New pathogens such as Pasteurella skyensis have been described, and antimicrobial compounds for the control of disease have been replaced by alternative methods, such as probiotics. Consideration is given to all the bacterial taxa which have at some time been reported as fish pathogens, whether they are secondary invaders of already damaged tissues or serious, primary pathogens.
Bacterial Biofilms
This volume tends to focus on the biology of biofilms that affect human disease. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth. The next chapters are devoted to common problematic biofilms, those that colonize venous and urinary catheters. The final series of chapters examines biofilm formation by four species that are important pathogens and well studied models, one of which, Yersinia pestis, cleverly adopts a biofilm state of growth within its insect vector to promote disease transmission to mammalian hosts.
Bacterial and Bacteriophage Genetics
Genetic investigations and manipulations of bacteria and bacteriophage have made vital contributions to our basic understanding of living cells and to the development of molecular biology and biotechnology. This volume is a survey of the genetics of bacteria and their viruses, and it provides students with a comprehensive introduction to this rapidly changing subject. The book is written for upper level undergraduates and beginning graduate students, particularly those who have had an introductory genetics course.
Axonal branching and recovery of coordinated muscle activity after transsection of the facial nerve in adult rats
Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets
Axon growth and guidance
The complexarchitectureofneuronal networks togetherwith the extraordinary associated functions make the nervous system a fascinating biological structure. The considerable work performed to explore this cellular machinery is nowadays successfulbecause the mysteryofnervous system developmentisbeing unravelled. As described in their outstanding review published 10 years ago in Science.' Marc Tessier-Lavigne and Corey Goodman-the pioneers of the molecular era of axon guidance-summarized the assembly of nervous system connections as a subtle game of attraction and repulsion of neuronal growth cones. The cellular ballet ensuring the formation of billions of synapses, which ultimately gives rise to the highest cognitive functions, is primarily orchestrated by a step-by-step mechanism of growth driven by multiple molecular cues. While our general concept of axon guidance remains identical, a profound evolution ofour knowledge ofthe molecular identityofthe guidance cues together with their interactions and signalling pathways occurred over the past ten years.
Avian Navigation : Pigeon Homing as a Paradigm
This monograph summarizes our current knowledge about pigeon homing, about the birds' application of a sun compass and a magnetic compass, of a visual topographical map within a familiar area and -- most surprisingly -- of an olfactory map using atmospheric chemosignals as indicators of position in distant unfamiliar areas
Autoformation et aide au diagnostic en hématologie avec le logiciel ADH = Self-study and diagnostic aid in hematology with ADH software
The software includes a rich iconography on blood and marrow cells which will complement the knowledge in cytology of hematologists. Certain cytological abnormalities encountered in certain pathologies are also presented.
Auditory Trauma, Protection, and Repair
Protection and Repair presents recent developments in auditory research and their potential translation to the clinical setting. In particular the authors address the major entities of peripheral auditory trauma, discuss the underlying mechanisms, the central nervous system consequences, protective interventions and finally explore the possibilities to restore cochlear morphology and function.Two themes run through the chapters in this book: cellular homeostasis and cell death. In the broadest sense, all auditory pathologies are disorders of cellular homeostasis.
Auditory signal processing : Physiology, psychoacoustics, and models
The volume includes a total of 62 invited papers, organized into 12 broad thematic areas: cochlear signal processing; brainstem signal processing; pitch; frequency modulation; streaming; amplitude modulation; responses to complex sounds; speech; comodulation masking release; binaural hearing; temporal coding; and plasticity
Auditory Perception of Sound Sources
Auditory Perception of Sound Sources covers higher-level auditory processes that are perceptual processes. The chapters describe how humans and other animals perceive the sounds that they receive from the many sound sources existing in the world. This book will provide an overview of areas of current research involved with understanding how sound-source determination processes operate. This book will focus on psychophysics and perception as well as being relevant to basic auditory research.
Atlas of Woody Plant Stems : Evolution, Structure, and Environmental Modifications
he „Atlas of Woody Plant Stems“ is a com- Naturally, it was impossible to cover completely the Tprehensively illustrated book with short, in- enormous variability of plant life forms. We have formative texts. We chose this layout because plant tried, however, to illustrate the main principles and anatomy and morphology can only be conveyed by features. Many decades of collection and prepa- detailed pictures. In addition, a vivid presentation tion provided the basis for this book.
Atherosclerosis : Diet and Drugs
Divided into four parts and intends to give an overview on the pathogenesis of atherosclerosis, established treatment and prevention regimen, and of perspectives for the development of new treatment modalities.
Asymmetric Cell Division
Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Associative and endophytic nitrogen-fixing bacteria and cyanobacterial associations
Associative and Endophytic Nitrogen-fixing Bacteria and Cyanobacterial Associations This book is part of the seven-volume series that was launched a few years ago with the ambitious objectives of reviewing the field of nitrogen fixation from its earliest beginnings through the millennium change and of consolidating the relevant information - from fundamental to agricultural and environmental aspects – all in one place. Volume 5 covers the biology of bacteria that associate with n- leguminous plants. The subject matter includes a wide range of associations; it covers the bacterial species that associate either with the surface or within the tissues of grasses (often referred as plant growth-promoting rhizobacteria) and also the symbiotic associations that cyanobacteria form with fungi, algae, and both lower and higher plants. This volume does not deal with the Frankia-actinorhizal plant associations, which is the topic of Volume 6
Association Mapping in Plants
For the past decade, there has been success in using conventional map-based strategies in identification and cloning of quantitative trait loci (QTL) in model plant species including tomato and Arabidopsis. These quantitative traits are generally the products of many loci with varying degrees of effect upon the observed phenotypes. Recently, a new approach to genetic mapping has emerged called association mapping. This new technique takes into account the thousands of genes to evaluate for QTL effect and is a more efficient approach that does not require generation of segregating populations/large numbers of progeny. As it can utilize all of the historic recombination events in a diverse population of individuals it can generate higher resolution genetic maps and, is needed to complement current map based cloning methods.
Ascochyta blights of grain legumes
Ascochyta blights consistently affect large areas of grain legume production (pea, lentil, chickpea and faba bean) in all countries where they are cultivated. These diseases are capable of causing large yield losses under conducive environmental conditions. This book considers the state of the art by taking a comparative approach of Ascochyta blight diseases of cool season food and feed legumes. Topics considered are pathogen diversity, legume genetics and breeding, and integrated disease management.
Artificial oxygen carrier; its frontline
This volume of the Keio University International Symposia for Life Sciences and Medicine contains the proceedings of the 13th symposium held under the sponsorship of the Keio University Medical Science Fund. The fund was est- lished by the generous donation of the late Dr. Mitsunada Sakaguchi. The Keio University International Symposia for Life Sciences and Medicine constitute one of the core activities sponsored by the fund,of which the objective is to contribute to the international community by developing human resources, promoting scienti?c knowledge, and encouraging mutual exchange. Each year, the Committee of the International Symposia for Life Sciences and Medicine selects the most signi?cant symposium topics from applications received from the Keio medical community. The publication of the proce- ings is intended to publicize and distribute the information arising from the lively discussions of the most exciting and current issues presented during the symposium.
Artificial intelligence in drug design
Looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future.
Arthropod Diversity and Conservation
Despite their enormous bulk and complexity of architecture, plants make up only around a quarter of a million of the 8 million or so species on Earth. The major components of biodiversity, instead, are the smaller, largely unseen, silent majority of invertebrates – most of which are arthropods. Vertebrates, a mere blip on the biotic horizon, are elevated in importance in the bigger scheme of things only by the human psyche. This collection of more than 30 peer-reviewed papers focuses on the diversity and conservation of arthropods, whose species inhabit virtually every recess and plane – and feature somewhere in virtually every food web – on the planet. Highlighting issues ranging from large-scale disturbance to local management, and from spatial heterogeneity to temporal patterns, these papers reflect some of the most exciting new research taking place today – and in some of the most biodiverse corners of the planet.
