الصفحة 102
الصفحة 102
Analysis and Simulation of Contact Problems
Contact mechanics was and is an important branch in mechanics which covers a broad field of theoretical, numerical and experimental investigations. In this carefully edited book the reader will obtain a state-of-the-art overview on formulation, mathematical analysis and numerical solution procedures of contact problems. The contributions collected in this volume summarize the lectures presented during the 4th Contact Mechanics International Symposium (CMIS) held in Hannover, Germany, 2005, by leading scientists in the area of contact mechanics.
Analysis and evaluation of a proposed human resources management system using success assessment models
Aims to develop a comprehensive model of human resources information systems (HRIS) and assess the success of it .There are six critical success measures in this model, namely perceived HRIS system quality, perceived HRIS information quality, perceived HRIS ease of use, perceived HRIS usefulness, HRIS user satisfaction, and overall HRIS success.
Analysis and Design of Advanced Multiservice Networks Supporting Mobility, Multimedia, and Internetworking : COST Action 279 Final Report
This book reports on the state-of-the-art work developed during the four years of operation of COST Action 279, Analysis and Design of Advanced Multiservice Networks Supporting Mobility, Multimedia, and Internetworking, by its participating researchers, originating from over 40 research institutions from the academic, industrial, and telecom operator worlds. The work includes both fundamental, methodological, and applied aspects of network performance evaluation and design. The book contains a detailed account of the work developed, supported on an extensive bibliography of material published in the peer-reviewed literature.
Analysis and Control of Ultrafast Photoinduced Reactions
The present monograph summarizes, in a comprehensive way, several years of joint experimental and theoretical frontier research on ultrafast laser-induced molecular dynamics and its control. Emphasis is set on the characterization of the nuclear dynamics within molecular systems in various environments (gas phase, surfaces, solids, solution, strong fields) triggered by optical excitations spanning from the infrared to the ultraviolet. Building on the converged analysis between experiment and theory, control of chemical reactions is established by means of optimally shaped laser pulses. This paves the road toward new applications and future challenges in this rapidly developing research field.
Analog Circuit Design : RF Circuits : Wide band, Front-Ends, DAC's, Design Methodology and Verification for RF and Mixed-Signal Systems, Low Power and Low Voltage
Analog Circuit Design contains the contribution of 18 tutorials of the 14th workshop on Advances in Analog Circuit Design. Each part discusses a specific todate topic on new and valuable design ideas in the area of analog circuit design. Each part is presented by six experts in that field and state of the art information is shared and overviewed. This book is number 14 in this successful series of Analog Circuit Design, providing valuable information and excellent overviews of analog circuit design, CAD and RF systems.
Analisi di Rasch e questionari di misura : Applicazioni in medicina e scienze sociali = Rasch analysis and measurement questionnaires: Applications in medicine and social sciences
Evaluation questionnaires are the most used tools nowadays in the field of medicine and the human sciences to evaluate variables such as disability, altruism or pain. However, clinicians are often unfamiliar with these tools. What do they really measure? How are the results to be interpreted? This book tries to answer these questions.
Analgesia
Analgesics are among the oldest drugs described, albeit not necessarily for medicinaluse. Forexample,theSumeriansisolatedopioids(probablyfortheir euphoric effects) in the third millennium b. c. and the use of willow bark (salicin) for fever was ?rst reported in the eighteenth century. Both types of drugs are still in use, but today they are supplemented by a wide array of substances ranging from antidepressants to ion channel blockers. Not all of theseareprescribedbyphysicians. Manycompoundsaresoldoverthecounter and thus available to the public for self-medication. As a result, analgesics are also the most misused class of drugs and are the culprit for a multitude of healthproblemsdueto untoward sideeffects. Thisvolumeattemptstosummarizethecurrentstateofknowledgeonme- anisms underlying the various effects of these drugs, their side effect pro?les, and their indications and contraindications in clinical use.
An Introduction to Scientific Computing : Twelve Computational Projects Solved with MATLAB
This book provides twelve computational projects aimed at numerically solving problems from a broad range of applications including Fluid Mechanics, Chemistry, Elasticity, Thermal Science, Computer Aided Design, Signal and Image Processing. For each project the reader is guided through the typical steps of scientific computing from physical and mathematical description of the problem, to numerical formulation and programming and finally to critical discussion of numerical results. Considerable emphasis is placed on practical issues of computational methods. The last section of each project contains the solutions to all proposed exercises and guides the reader in using the MATLAB scripts.
An introduction to medicinal chemistry
Providing an introduction to medicinal chemistry, this resource covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug
An Introduction to Mathematics of Emerging Biomedical Imaging
Biomedical imaging is a fascinating research area to applied mathematicians. Challenging imaging problems arise and they often trigger the investigation of fundamental problems in various branches of mathematics. This is the first book to highlight the most recent mathematical developments in emerging biomedical imaging techniques. The main focus is on emerging multi-physics and multi-scales imaging approaches. For such promising techniques, it provides the basic mathematical concepts and tools for image reconstruction. Further improvements in these exciting imaging techniques require continued research in the mathematical sciences, a field that has contributed greatly to biomedical imaging and will continue to do so.
An introduction to generative drug discovery
Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.
An Introduction to Echo Analysis : Scattering Theory and Wave Propagation
The use of various types of wave energy is an increasingly promising, non-destructive means of detecting objects and of diagnosing the properties of quite complicated materials. An analysis of this technique requires an understanding of how waves evolve in the medium of interest and how they are scattered by inhomogeneities in the medium. These scattering phenomena can be thought of as arising from some perturbation of a given, known system and they are analysed by developing a scattering theory. This monograph provides an introductory account of scattering phenomena and a guide to the technical requirements for investigating wave scattering problems.
An Introduction To Chemoinformatics
This, the first text written specifically for this field, aims to provide an introduction to the major techniques of chemoinformatics. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature.
An introduction to bioanalysis of biopharmaceuticals
Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.
An ecological and societal approach to biological control
Biological control is among the most promising methods for control of pests (including vectors), diseases and weeds. In this book ecological and societal aspects are for the first time treated together. In an ecological approach the aim is to evaluate the significance of certain biological properties like biodiversity and natural habitats. Also, it is important to see biological control from an organic (or ecological) farming point of view. In a societal approach terms like ‘consumer’s attitude’, ‘risk perception’, ‘learning and education’ and ‘value triangle’ are recognised as significant for biological production and human welfare.
Amplification of Chirality
Amplification of Chirality presents critical reviews of the present position and future trends in modern chemical research. The book contains short and concise reports on chemistry. Each is written by the world renowned experts. Still valid and useful after 5 or 10 years, more information as well as the electronic version of the whole content available at: springerlink.com.
Amino acids and the asymmetry of life : Caught in the act of formation
This book describes how the basic building blocks of life, the amino acids, formed. After a comprehensible introduction into stereochemistry, the author addresses the inherent property of amino acids in living organisms, namely the preference for left-handedness. What was the cause for violation of parity of amino acids in the emergence of life on Earth? All the fascinating models proposed by physicists, chemists and biologist are vividly presented including the scientific conflicts.
Amartya Sens Capability Approach: Theoretical Insights and Empirical Applications
Kuklys examines how Nobel Prize-winning economist Amartya Sen’s approach to welfare measurement can be put in practice for poverty and inequality measurement in affluent societies such as the UK. Sen argues that an individual’s welfare should not be measured in terms of her income, but in terms what she can actually do or be, her capabilities. In Chapters 1 and 2, Kuklys describes the capability approach from a standard welfare economic point of view and provides a comprehensive literature review of the empirical applications in this area of research. In the remaining chapters, novel econometric techniques are employed to operationalise the concepts of functionings and capability to investigate inequality and poverty in terms of capability in the UK. Kuklys finds that capability measurement is always a useful complement to traditional monetary analysis, and particularly so in the case of capability-deprived disabled individuals.
Alzheimer's disease : Peptide vaccine and immunotherapy
Peptide vaccines and immunotherapies against aggregating proteins involved in the pathogenesis and progression of Alzheimer's disease (AD) the ẞ-amyloid peptide (Aẞ) and tau are promising therapeutic avenues against AD. Two decades of effort has led to the controversial United States Food and Drug Administration (FDA) approval of the monoclonal antibody Aducamumab (Aduhelm), which has subsequentially sparked the revival and expedited review of promising monoclonal antibody immunotherapies that target Aẞ.
Alzheimers disease : Cellular and molecular aspects of Amyloid beta
This book contains a survey of present-day research into the biomedical fundamentals of Alzheimer’s disease (AD). It contains 20 chapters dealing with widely ranging topics, all of which have a bearing upon the understanding and treatment of AD. Starting with a broad survey of the contribution that the various microscopical techniques (light microscopy, electron microscopy, atomic force microscopy)
