الصفحة 100
الصفحة 100
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A Time for Metabolism and Hormones

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

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A Successful Transformation? : Restructuring of the Czech Automobile Industry

This book investigates the complex processes of the post-1990 transformation in the Czech automotive industry and its selective integration in the West European automobile manufacturing system. The post-1990 restructuring of the Czech automotive industry is analyzed in the context of its pre-1990 development and in the context of the Central and East European automobile industry as a whole. Specifically, the book examines the development and post-1990 restructuring of the Czech passenger car industry, the components industry and truck manufacturing. Major topics covered include the development of the Czech automotive industry before 1990, the detailed case study of Škoda Auto, the effects of the post-1990 privatization in the Czech automotive industry, the role and effects of foreign direct investment during the post-1990 restructuring, the restructuring of the Czech truck industry, and the rapid development of the automotive components manufacturing.

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A Study about Prevalence of Thalassemia Complications in Syrian Patients

Inherited haemoglobin disorders, including thalassemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of α-thalassemia and β-thalassemia, including the co-inheritance of β-thalassemia with haemoglobin E resulting in haemoglobin E/β-thalassemia, have been described. The disease hallmarks include imbalance in the α/β-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, compensatory hemopoietin expansion, hypercoagulability, and increased intestinal iron absorption. The complications of iron overload, arising from transfusions that represent the basis of disease management in most patients with severe thalassemia. The mature Hb molecule is a tetramer composed of 2 a-globin and 2 b-globin polypeptides, which assemble, along with a heme prosthetic group, to form the complete molecule.

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A Sea Change: The Exclusive Economic Zone and Governance Institutions for Living Marine Resources

A Sea Change in a Changing Sea The oceans, seas and coastal areas encompass over 70% of the earth’s surface. They are a critical driver of the earth’s hydrologic cycle and climate system, important for c- merce, transport, and tourism, a source of economically important living marine resources, minerals such as hydrocarbons, as well as new pharmaceutical compounds. The marine environment provides essential habitats for thousands of marine living 1 2 resources, which in turn contribute significantly to global food security, employment, 3 and trade. Overall, the sea’s contribution to human welfare, in terms of market and non-market resources and environmental services, has been estimated at US$21 trillion/year (Costanza, 2000). However, despite the importance of the ocean realm to humans, there is a growing sense that human impacts are destabilizing this system. Some experts believe that current fishing levels are approaching or exceeding the total 4 productivity of the ocean ecosystem (National Research Council, 1999).

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A Roadmap for Formal Property Verification

Develops the answers to these questions and fits them into a roadmap for formal property verification – a roadmap that shows how to glue FPV technology into the traditional validation flow. A Roadmap for Formal Property Verification explores the key issues in this powerful technology through simple examples – you do not need any background on formal methods to read most parts of this book.

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A Risk-Benefit Perspective on Early Customer Integration

Customer integration in the early innovation phase has been considered the method of choice in theory and practice. Growing experience with the concept has shown unexpected side effects that may even outweigh its recognized advantages. Therefore, management needs to be able to assess in advance whether the involvement of customers will add overall value to each particular innovation project. To support but not to replace the final managerial decision, a mathematical formula is developed. It can be applied to all kinds of process structures, takes into account the risks and benefits contingent on a company's situation as well as risk-reducing and benefit-increasing measures and translates them into numerical values. The resulting figure indicates the prospective value of customer integration in a specific project.

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A Reappraisal of the Ascending Systems in Man, with Emphasis on the Medial Lemniscus

Based on material assembled by Dr Jaap HR Schoen who was one of the few neuroanatomists to apply the Nauta method to human material. Gaining insight in the consequences of longitudinal damage to the human spinal cord is necessary before reimplantation of the avulsed rootlets or an autologous transplant can be performed in man.

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A Prodigy of Universal Genius : Robert Leslie Ellis, 1817-1859

Written by a diverse team of experts, the chapters in the book’s first part contain in-depth examinations of, among other things, Ellis’s family, education, Bacon scholarship and mathematical contributions. The second part consists of annotated transcriptions of a selection of Ellis’s diaries and correspondence. Taken together, A Prodigy of Universal Genius: Robert Leslie Ellis, 1817–1859 is a rich resource for historians of science, historians of mathematics and Victorian scholars alike.

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A practical guide to corporate finance : Breaking the financial lce

Offers an approachable guide to all key concepts within corporate finance. Emphasizing the use of common sense rather than number-crunching models, A practical guide to corporate finance begins with the basics of how to read financial statements and how to estimate future cash flows. It also includes a guide to subjects such as capital budgeting decisions, the cost of financing for businesses, cash and working capital management, The process of business valuation, and how stock markets work. This textbook breaks the financial ice by offering real, practical advice, helping the reader to avoid common pitfalls, and translate the 'financialese', or business jargon that can cause confusion for those without a financial or banking background.

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A Portrait of State-of-the-Art Research at the Technical University of Lisbon

This book contains the edited version of the invited lectures that were delivered by prominent researchers at UTL. This book brings together in a review manner a comprehensive summary of high quality research contri- tions across basic and applied sciences. The contributing papers are organized around the following major areas: – Emergent areas (Nanosciences, Quantic Computations and Infor- tion, Risk and Volatility in Financial Markets); – Basic Sciences (Mathematics, Physics, Chemistry and Materials); – Social Sciences, Economics and Management Sciences; – Life Sciences and Biotechnology; – Engineering and Technologies – Nature, Environment and Sustainability; – Public Health, Food Quality and Safety; – Health and Sport Sciences; – Urbanism, Transports, Architecture, Arts and Design.

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A Life Course Perspective on Health Trajectories and Transitions

This book examines health trajectories and health transitions at different stages of the life course, including childhood, adulthood and later life. It provides findings that assess the role of biological and social transitions on health status over time. The essays examine a wide range of health issues, including the consequences of military service on body mass index, childhood obesity and cardiovascular health, socio-economic inequalities in preventive health care use, depression and anxiety during the child rearing period, health trajectories and transitions in people with cystic fibrosis, and oral health over the life course.

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A Guide to Sustainable Corporate Responsibility : From Theory to Action

Discusses the challenges and opportunities faced by companies in an age that increasingly values sustainability and demands corporate responsibility. Beginning with the historical development of corporate responsibility, this book moves from academic theory to practical application. It points to ways in which companies can successfully manage their transition to a more responsible, sustainable way of doing business, common mistakes to avoid and how the UN Sustainable Development Goals are integral to any sustainability transformation.

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A Graph-Theoretic Approach to Enterprise Network Dynamics

This monograph treats the application of numerous graph-theoretic algorithms to a comprehensive analysis of dynamic enterprise networks. Network dynamics analysis yields valuable information about network performance, efficiency, fault prediction, cost optimization, indicators and warnings.

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A First Course in Harmonic Analysis

This book is a primer in harmonic analysis using an elementary approach. Its first aim is to provide an introduction to Fourier analysis, leading up to the Poisson Summation Formula. Secondly, it makes the reader aware of the fact that both, the Fourier series and the Fourier transform, are special cases of a more general theory arising in the context of locally compact abelian groups. The third goal of this book is to introduce the reader to the techniques used in harmonic analysis of noncommutative groups. There are two new chapters in this new edition. One on distributions will complete the set of real variable methods introduced in the first part. The other on the Heisenberg Group provides an example of a group that is neither compact nor abelian, yet is simple enough to easily deduce the Plancherel Theorem.

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A Field Guide to Algebra

Focuses on the structure of fields and is intended for a second course in abstract algebra. Besides providing proofs of the transcendance of pi and e, the book includes material on differential Galois groups and a proof of Hilbert's irreducibility theorem. The reader will hear about equations, both polynomial and differential, and about the algebraic structure of their solutions. In explaining these concepts, the author also provides comments on their historical development and leads the reader along many interesting paths. In addition, there are theorems from analysis: as stated before, the transcendence of the numbers pi and e, the fact that the complex numbers form an algebraically closed field, and also Puiseux's theorem that shows how one can parametrize the roots of polynomial equations, the coefficients of which are allowed to vary. There are exercises at the end of each chapter, varying in degree from easy to difficult. To make the book more lively, the author has incorporated pictures from the history of mathematics, including scans of mathematical stamps and pictures of mathematicians.

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A Dressing Method in Mathematical Physics

The monograph is devoted to the systematic presentation of the so called "dressing method" for solving differential equations (both linear and nonlinear) of mathematical physics. The essence of the dressing method consists in a generation of new non-trivial solutions of a given equation from (maybe trivial) solution of the same or related equation.

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A Companion to islamic art and architecture ; 2 Vol. Set : Blackwell companions to art history

Bridges the gap between monograph and survey text by providing a new level of access and interpretation to Islamic art. The more than 50 newly commissioned essays revisit canonical topics, and include original approaches and scholarship on neglected aspects of the field. showcases more than 50 specially commissioned essays and an introduction that survey Islamic art and architecture in all its traditional grandeurEssays are organized according to a new chronological-geographical paradigm that remaps the unprecedented expansion of the field and reflects the nuances of major artistic and political developments during the 1400-year span. Represents recent developments in the field, and encourages future horizons by commissioning innovative essays that provide fresh perspectives on canonical subjects, such as early Islamic art, sacred spaces, palaces, urbanism, ornament, arts of the book, and the portable arts while introducing others that have been previously neglected, including unexplored geographies and periods, transregional connectivities, talismans and magic, consumption and networks of portability, museums and collecting,

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A City in Blue and Green : The Singapore Story

Highlights Singapore’s development into a city in which water and greenery, along with associated environmental, technical, social and political aspects have been harnessed and cultivated into a liveable sustainable way of life. It is also a story about a unique and thoroughgoing approach to large-scale and potentially transferable water sustainability, within largely urbanized circumstances, which can be achieved, along with complementary roles of environmental conservation, ecology, public open-space management and the greening of buildings, together with infrastructural improvements.

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A Century of Ideas : Perspectives from Leading Scientists of the 20th Century

Shortly after its inauguration in 1985 the Birla Science Centre, Hyderabad, India, started a series of lectures by Nobel Laureates and other scientists of international renown, usually in Physics and Astronomy, sometimes in Life Sciences and Chemistry. The present collection mostly consists of lectures on frontier topics. The transcript of each lecture is preceded by a short biography of the Nobel Laureate/Scientist in question.

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6G Mobile Wireless Networks

Specifically, this book covers the following topics: 6G Use Cases, Requirements, Metrics and Enabling Technologies, PHY Technologies for 6G Wireless, Reconfigurable Intelligent Surface for 6G Wireless Networks, Millimeter-wave and Terahertz Spectrum for 6G Wireless, Challenges in Transport Layer for Tbit/s Communications, High-capacity Backhaul Connectivity for 6G Wireless, Cloud Native Approach for 6G Wireless Networks, Machine Type Communications in 6G, Edge Intelligence and Pervasive AI in 6G, Blockchain: Foundations and Role in 6G, Role of Open-source Platforms in 6G, and Quantum Computing and 6G Wireless.

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