الصفحة 10
الصفحة 10
The Chemokine Receptors
To date, there are over twenty different chemokine receptors, binding nearly fifty unique ligands that have been identified. In Chemokine Receptors, leading investigators attempt to distill the large body of literature ranging from basic molecular and cellular mechanism of chemokine receptors, to physiological and pathological roles of chemokines. Chemokines exhibit a tremendous functional diversity and participate in a wide variety of processes that include inflammation, innate and adaptive immunity, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology and viral pathogenesis. Chemokine Receptors targets the pharmaceutical industry, provides an authoritative perspective on the future direction of this field, and insights into areas of active development of novel therapeutics.
The Cell Cycle in the Central Nervous System
Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system (CNS) to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.
The Cambridge handbook of digital evidence in criminal investigations
Delves into the intricate matter of digital evidence collection, adopting a comparative and intra-disciplinary approach. It focuses specifically on the increasingly important role of online service providers in criminal investigations, which marks a new paradigm in the field of criminal law and criminal procedure, raising particular challenges and fundamental questions. This scholarly work facilitates a nuanced understanding of the multi-faceted and cross-cutting challenges inherent in the collection of digital evidence, as it navigates the contours of current and future solutions against the backdrop of ongoing European and international policy-making.
The Bluefin Tuna Fishery in the Bay of Biscay : Its Relationship with the Crisis of Catches of Large Specimens in the East Atlantic Fisheries from the 1960s
It reconstructs the possible methods used to catch large spawners in the Strait of Gibraltar thousands of years ago and describes the much more recent overfishing that led to a great reduction in the catches of the trap fishery on the area and the disappearance of the northern European fisheries. It is the first book to relate the overfishing of juvenile fishes in certain areas to the decline of large spawners in other very distant areas, revealing one of the main underlying causes of this decline, which has remained a mystery to the fishing sector and scientists alike for over 50 years. This finding should serve to prevent similar cases from arising in the future.
The architecture of persistence : Designing for future use
Why do some buildings last for generations as beloved and useful places, while others do not? How can designers today create buildings that remain useful into the future? While architects and theorists have offered a wide range of ideas about building for change, this book focuses on persistent architecture: the material, spatial, and cultural processes that give rise to long-lived buildings. Organized in three parts, this book examines material longevity in the face of constant physical and cultural change, connects the dimensions of human use and contemporary program, and discusses how time informs the design process. Featuring dozens of interviews with people who design and use buildings, and the close analysis of over a hundred historic and contemporary projects, the principles of persistent architecture introduced here address urgent challenges for contemporary practice while pointing towards a more sustainable built environment in the future. The Architecture of Persistence: Designing for Future Use offers practitioners, students, and scholars a set of principles and illustrative precedents exploring architecture's unique ability to connect an instructive past, a useful present, and an unknown future
The Allegheny Woodrat : Ecology, Conservation, and Management of a Declining Species
Once a common resident of the northeastern United States, the Allegheny woodrat (Neotoma magister) has now disappeared from areas where it was once abundant. The mystery of its decline has confounded biologists for three decades, but offers warnings for the future of other small, inconspicuous native mammals. Mammalogists John Peles and Janet Wright have synthesized current knowledge of the species in book form. The Allegheny Woodrat: Ecology, Conservation, and Management of a Declining Species provides the reader with a coherent, integrated picture illustrating the current status and distribution of the woodrat as well as the factors that have contributed to its decline. It provides background of the mammal’s ecology and genetics and insight into its future through conservation initiatives and management programs. Through hard lessons learned and relayed in the book, the editors and contributors hope to provide both good models for, and some caveats to, general principles that may be applied to the study of other declining species. It is a real and instructive study for ecology, management and conservation.
The Academic Book of the Future
Interrogates current and emerging contexts of academic books from the perspectives of thirteen expert voices from the connected communities of publishing, academia, libraries, and bookselling.
The 3rd international conference on current and future trends in bridge design, construction and maintenance ; April 28-30, 2003 ; Shanghai, China
This title helps to ensure access to essential engineering content from past to present
Textbook of Healthcare Ethics
1 Historical Introduction INTRODUCTION This chapter is mainly about the history of medicine and its ethics. As usually c- ceived, history is retrograde: It is what happened yesterday, and, much as we may try, it is what happened yesterday seen with a set of today’s eyes. Trying to understand yesterday’s culture may help us put on a pair of corrective glasses, but it fails in - tirely correcting our vision. Contemporary cultural anthropology may likewise help us understand the way today’s events and cultural habits shape what we call history tomorrow. Past events and the kaleidoscopic pattern of today’s cultures may help guide us into a future that in at least some respects is ours to forge. Learning about ethics yesterday and thinking about ethics as it expresses itself in various cultures today can help us shape the ethics of tomorrow: This is true whether we are speaking of that part of social ethics called “medical” or of any other part of social ethics. The social aspects of medical practice—how the institution called medicine fits into and works within the greater society called culture—shape the way its ethics ultimately must play itself out.
Text, Speech and Dialogue ; 5th International Conference, TSD 2002, Brno, Czech Republic September 9-12, 2002. Proceedings
This volume contains proceedings of the 5th International Conference Speech and Dialogue (TSD) Conference, held in Brno, Czech Republic, September 9–12, 2002. It was international forum about the basic ?elds of NLP. the communication between man and computers has displayed a one-way nature, humans have to know how the - chines work and only then can they “understand” them. The opposite, however, is still quite far from being real, our understanding of how our “user-friendly” computers can understand us humans is not deep enough yet. A lot of work has to be done both in the near and distant future. Let TSD 2002 be a modest contribution to this goal. The conference also serves well in its second purpose: to facilitate researchers meeting in the NLP ?eld from Western and Eastern Europe.
Terrestrial Trunked Radio - TETRA : A Global Security Tool
Terrestrial Trunked Radio (TETRA) has become the tool to design any type of public security systems, in particular due to the strongly increased security demands for mobile systems. In this book, the authors show how TETRA can be strongly improved and these improvements will most probably be part of future TETRA standards. The areas examined include channel assignment and multiple access techniques, video transmission, wireless LAN integration, and the establishment of multiple wireless mesh networks. Since the requirements for these networks is security, the authors show that innovative techniques such as those based on chaotic signals can be used in order to maximize security.
Templates in Chemistry II
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage includes all areas of chemical science including the interfaces withrelated disciplines such as biology, medicine and materials science. The goal of each thematic volume is togive the nonspecialist reader, whether at the university or in industry, a comprehensive overview of an areawhere new insights are emerging that are of interest to a larger scientific audience.As a rule, contributions are specially commissioned.
Telecommunications Planning : Innovations in Pricing, Network Design and Management
Focuses on the latest methodological developments in three key areas---pricing of telecommunications services, network design, and resource allocation. These three elements are most relevant to current telecommunications planning. The first five chapters cover global deregulation of the telecommunications industry, effective pricing and revenue management, as well as an understanding of competitive pressures are key factors that will improve revenue in telecommunications companies. These chapters present some novel ideas related to pricing (including auction-based pricing of network bandwidth) and modeling competition in the industry. The next seven chapters outline what successful telecommunications companies of the future will need to do in order to minimize their costs and still meet customer expectations. In this context the optimal design/provisioning of telecommunication networks plays an important role. These chapters focus on network design for a wide range of technologies including SONET, SDH, WDM, and MPLS. They include the latest research developments related to the modeling and solving of network design problems. The final six chapters provide insightful solutions to several resource allocation problems. Day-to-day management/control of telecommunications networks is dependant upon the optimal allocation of resources.
Teeth extraction and immediate implant insertion
The future of oral implantology is very positive and is expected to continue as one of the fastest and largest growth areas in medicine. Dental implant therapy is a widely accepted treatment method for restoring chewing function in partially or fully edentulous patients.
Technical Universities : Past, present and future
This book analyses the past, present and future of the technical university as a single faculty independent institution. The point of departure is a view of changing academic realities, through which the identity as a technical university is challenged and reconstituted.
Techlash : The Future of the Socially Responsible Tech Organization
Applies proactive crisis management to the management of technology organizations to make them more sustainable and socially responsible for the betterment of humankind. It forecasts the unintended consequences of technology and offers methods to counteract it.
Teaching : Professionalization, Development and Leadership : Festschrift for Professor Eric Hoyle
The world-wide reform movement has now been in process for thirty years and it is therefore perhaps an appropriate point to consider its implications for the work of teachers thus far and to ponder on the future. It would be widely agreed that the reform movement in general, and in relation to teachers’ work in particular, has brought advantages and disadvantages. It has stimulated teacher development and increased the accountability of teachers to clients – including the state as client. On the other hand, it has led to the intensification of teachers’ work and to the deprofessionalisation as well as professionalisation of teachers. Moreover, it has increased the power of managerialism over the influence of professionalism. This book addresses these issues from different perspectives and in relation to different contexts. It also considers possible solutions to two problems in particular: how to achieve accountability without intensification, and how to ensure that school management and leadership functions to support and enhance teachers as professionals.
Task Models and Diagrams for Users Interface Design ; 5th International Workshop, TAMODIA 2006, Hasselt, Belgium, October 23-24, 2006. Revised Papers
The first workshopaimed at examining how multiple forms of task expressionscan sign- icantly increase or decrease the quality of user interface design. This is still the scope of the current edition; we tried to assemble papers that discuss how the complexity of HCI design and development can be managed with tasks, models and diagrams. Much like the previous editions, the selection of papers from the 2006 edition re?ects the broad scope of this ?eld, which cannot be labeled with a single title or term. The invited paper is by Jo¨ elle Coutaz and discusses meta-user interfaces for ambient spaces. Finding appropriate ways to design and develop user interfaces for interactive spaces is becoming an important challenge for the creation of future usable applications.
Targeted Radionuclide Tumor Therapy : Biological Aspects
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. The expanding array of new targeting molecules (recombinant antibodies or peptides) may increase the therapeutic efficacy. The title of this book "Targeted Radionuclide Tumor Therapy – Biological aspects" was selected to reinforce the concept that a major focus was devoted to understanding the biological effects of targeting and radiation. Furthermore, our rapidly expanding knowledge of low dose-rate effects, different types of cell death, autosensitization and the increasingly likely existence of cancer stem cells suggests to us that even more efficient approaches in targeting might be possible in the future.
System Software Reliability
Computer software reliability has never been more important. Today, computers are employed in areas as diverse as air traffic control, nuclear reactors, aircraft, real-time military, industrial process control, security system control, biometric scan-systems, automotive, mechanical and safety control, and hospital patient monitoring systems. Many of these applications require critical functionality as software applications increase in size and complexity. System Software Reliability is an introduction to software reliability engineering as well as a detailed survey of the state-of-the-art techniques, methodologies and tools used to assess the reliability of software and combined software-hardware systems. The most recent research results in the field are reported and future directions in the subject are signposted.
