الصفحة 10
الصفحة 10
Immunology, phenotype first : How mutations have established new principles and pathways in immunology
This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists.
Immanent Realism : An Introduction to Brentano
A set of knotty questions are implied in the very title of Brentano's work "Psychology from an empirical standpoint". To solve them, Albertazzi guides us systematically through Brentano's life and works, investigating into the inherent complexity of both his view of mental life and the related methodology. In so doing, she discloses a number of threads into the open texture of modern philosophy of mind." Lia Formigari, Ordinary professor of Philosophy of Language, La Sapienza, Rome, Italy
Imaging Pelvic Floor Disorders
This volume builds on the success of the first edition of Imaging Pelvic Floor Disorders and is aimed at those practitioners with an interest in the imaging, diagnosis and treatment of pelvic floor dysfunction. Concise textual information from acknowledged experts is complemented by high-quality diagrams and images to provide a thorough update of this rapidly evolving field. Introductory chapters fully elucidate the anatomical basis underlying disorders of the pelvic floor. State of the art imaging techniques and their application in pelvic floor dysfunction are then discussed in detail. Additions since the first edition include consideration of the effect of aging and new chapters on perineal ultrasound, functional MRI and MRI of the levator muscles.
Il disturbo bipolare = Bipolar disorder
Questo libro, frutto della collaborazione di tre esperti dell’argomento, ? una guida completa e pratica sulle cause, il trattamento e le implicazioni del disturbo bipolare, altrimenti definito come malattia maniaco-depressiva. Destinato a tutti coloro che soffrono di questa patologia, ma anche ai familiari che spesso la condividono intensamente, questo manuale prende in esame cause, sintomi e possibili terapie, fornendo inoltre una panoramica dei diversi tipi di supporto professionale che possono essere utili al paziente e a chi gli sta vicino. Il lettore trover? suggerimenti pratici su come affrontare e convivere con il disturbo, per esempio "monitorando" il proprio umore, oppure, su come gestire il denaro o risolvere problemi quali l’abitazione o le relazioni interpersonali, fino a come fruire degli aiuti offerti dalla societ?. La descrizione di storie reali - i box di sintesi posti alla fine dei vari capitoli - assieme ad indicazioni sulle organizzazioni cui fare riferimento e sugli web-forum dedicati a questo problema fanno s? che quest’opera possa fornire informazione e supporto a tutte le persone che devono affrontare la sconcertante turbolenza connessa al disturbo bipolare.
I recettori dellangiotensina : Dalla biologia molecolare alla terapia con gli antagonisti recettoriali
Describes all the structural and functional characteristics of angiotensin receptors, with particular reference to their molecular and pharmacological properties. The therapeutic applications of AT1 receptor antagonists and the results obtained from large trials are also discussed, especially in arterial hypertension, heart failure, diabetic nephropathy and stroke.
Hypocretins : Integrators of Physiological Signals
The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression.
Hypertension in the Elderly
Topics range from basic concepts, epidemiology and trials, and evaluation and management, to pharmacological treatment, special populations, and adherence, all presented with an emphasis on the optimal management of patients. The authors examine in detail the mechanisms of hypertension in the elderly, particularly age-related changes in vascular stiffness, and methodically review the lifestyle and outcomes trials that were conducted in older persons. The problems of clinical evaluation, secondary hypertension, and target organ damage are also fully addressed, and a practical approach is provided for correctly determining blood pressure, one of the most important tasks in evaluating an older patient. Extensive discussions of pharmacological therapy detail the role of individual drug classes, including diuretics and b-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, calcium antagonists, a-1 blockers, and combination drug therapies. Additional chapters focus on special populations, such as African Americans, patients with diabetes, and patients with arthritis, as well as on the clinician's role in improving therapeutic adherence in older patients. Offers family practitioners and general internists an up-to-date, user-friendly reference on the diagnosis, treatment, and complications of hypertension in the elderly.
Hydrological modelling and the water cycle : Coupling the atmospheric and hydrological models
This collected work reports on the state of the art of hydrological model simulation, as well as the methods for satellite-based rainfall estimation. Mainly addressed to scientists and researchers, the contributions have the structure of a standard paper appearing in most cited hydrological, atmospheric and climate journals. Several already-known hydrological models and a few novel ones are presented, as well as the satellite-based precipitation techniques. As the field of hydrologic modeling is experiencing rapid development and transition to application of distributed models, many challenges including overcoming the requirements of compatible observations of inputs and outputs are addressed.
Hydra = هايدرا
Forgery involves the use of advanced algorithms to replicate and distribute deceptive products across various categories, casting shadows of doubt on the authenticity of goods. Although counterfeit detection can be useful in identifying and mitigating fraudulent activities, the widespread presence of counterfeit goods poses significant dangers, undermining consumer confidence and brand reputation. To underscore the severity of this issue, consider instances such as fake luxury items flooding the market, counterfeit electronics compromising safety, or bogus pharmaceuticals endangering health. Addressing this issue is critical in maintaining the integrity of brands, safeguarding consumer well-being, and preserving trust in the marketplace. The ability to distinguish between authentic and counterfeit products is paramount in ensuring accurate decision-making and preventing the harmful consequences of fraudulent goods. This technological context underscores the urgency of developing and deploying cutting-edge solutions to combat the evolving landscape of product forgery. Hydra emerges as a robust solution, utilizing a comprehensive approach that includes extracting posts and images from search engine tools, and is integrated with AI models to detect forgery. The Hydra platform not only provides users with a powerful tool for detecting counterfeit products but also offers tangible benefits such as enhanced brand security, increased awareness about the prevalence of forgeries, and the opportunity to actively participate in a real-time community.
Human origins and environmental backgrounds
Human Origins and Environmental Backgrounds is a benchmark compendium of research that presents itself at a major paradigm shift in paleoanthropology. The editors offer a variety of theoretical approaches to puzzles on the place of the Hominidae, particularly Homo sapiens, among the Primates, including our unique bipedal positional behavior and social structure and the selective factors that might have been involved in our evolution in the broad context of Miocene and later environments. The contributors represent several generations of pioneering laboratory and field researchers from Japan, France and the United States, who have worked together over the past 40 years and who have trained future leaders in evolutionary anthropology and experimental primatology. This volume, compiled by the leading experts in the field, explores the interface between hominid origins and palaeoenvironments.
Human mitochondrial DNA and the evolution of homo sapiens
Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.
Human Challenge Studies in Endemic Settings : Ethical and Regulatory Issues
This book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide
Human and Animal Relationships
Pathogenic fungi are widely distributed and can infect many organisms, particularly humans, but also other vertebrates and insects. Due to a growing number of fungal infections, there is an increasing need to understand the interaction of pathogenic fungi with their hosts. This second completely updated and revised edition of Volume VI of The Mycota consists of state of the art reviews written by experts in the field, covering three major areas of this rapidly developing field. In the first part the current understanding of pathogenic fungi and the physiological reactions relevant for the pathogen - host interaction are elucidated. The second part describes novel technologies for the identification of proteins, virulence factors and mechanisms central to the host - pathogen interaction. The third part deals with the characterization of the host response towards pathogenic fungi and addresses timely clinical aspects.
Housing Market Dynamics in Africa
Utilizes new data to thoroughly analyze the main factors currently shaping the African housing market. Some of these factors include the supply and demand for housing finance, land tenure security issues, construction cost conundrum, infrastructure provision, and low-cost housing alternatives. Through detailed analysis, the authors investigate the political economy surrounding the continent’s housing market and the constraints that behind-the-scenes policy makers need to address in their attempts to provide affordable housing for the majority in need. With Africa’s urban population growing rapidly, this study highlights how broad demographic shifts and rapid urbanization are placing enormous pressure on the limited infrastructure in many cities and stretching the economic and social fabric of municipalities to their breaking point. But beyond providing a snapshot of the present conditions of the African housing market, the book offers recommendations and actionable measures for policy makers and other stakeholders on how best to provide affordable housing and alleviate Africa’s housing deficit.
Housing as Intervention : Architecture towards social equity
Across the world, the housing crisis is escalating. Mass migration to cities has led to rapid urbanisation on an unprecedented scale, while the withdrawal of public funding from social housing provision in Western countries, and widening income inequality, have further compounded the situation.
Hot Property : The Housing Market in Major Cities
This book discusses booming housing markets in cities around the globe, and the resulting challenges for policymakers and central banks. Cities are booming everywhere, leading to a growing demand for urban housing. In many cities this demand is out-pacing supply, which causes house prices to soar and increases the pressure on rental markets. These developments are posing major challenges for policymakers, central banks and other authorities responsible for ensuring financial stability, and economic well-being in general. This volume collects views from high-level policymakers and researchers, providing essential insights into these challenges, their impact on society, the economy and financial stability, and possible policy responses. The respective chapters address issues such as the popularity of cities, the question of a credit-fueled housing bubble, the role of housing supply frictions and potential policy solutions. Given its scope, the book offers a revealing read and valuable guide for everyone involved in practical policymaking for housing markets, mortgage credit and financial stability.
Hosting server management
At a high level, this project involves building and configuring a hosting server to provide website, email, and FTP hosting services to customers. The project also includes building a website where customers can register an account, choose hosting packages, and manage their hosting plan by linking the website to the hosting server's control panel using APIs. To effectively manage the hosting server and provide reliable hosting services to customers, it is important to have a deep understanding of the technologies and protocols involved in web hosting. This includes knowledge of web server software, email protocols, FTP protocols, and security best practices.
Homogenization of Partial Differential Equations
Homogenization is a method for modeling processes in microinhomogeneous media, which are encountered in radiophysics, filtration theory, rheology, elasticity theory, and other domains of mechanics, physics, and technology. These processes are described by PDEs with rapidly oscillating coefficients or boundary value problems in domains with complex microstructure. From the technical point of view, given the complexity of these processes, the best techniques to solve a wide variety of problems involve constructing appropriate macroscopic (homogenized) models. The present monograph is a comprehensive study of homogenized problems, based on the asymptotic analysis of boundary value problems as the characteristic scales of the microstructure decrease to zero. The work focuses on the construction of nonstandard models: non-local models, multicomponent models, and models with memory.
Homocysteine : Related Vitamins and Neuropsychiatric Disorders
There is an increasing interest in the connection between the homocysteine metabolism and neuropsychiatric disease with a steeply increasing number of publications. In particular, the association between homocysteine metabolism and cognitive decline/dementia attracts much interest. If simple, non-toxic homocysteine-lowering treatment with vitamins can reduce the incidence of, or delay the onset of dementia, it would have an enormous impact in societies with a rapidly increasing number of elderly at risk for dementia. This book summarises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects.
Holonic and multi-agent systems for manufacturing ; 3rd International Conference on industrial applications of holonic and multi-agent systems, HoloMAS 2007, Regensburg, Germany, September 3-5, 2007, Proceedings
The research of holonic and agent-based systems is developing rapidly, as is the community around this R&D topic. Despite the fact that real-life practical implementations of such systems remain surprisingly rare, the leaders in different branches of industry feel that the holonic and agent-based systems represent the only way to manage and control very complex, highly distributed systems in the future.
