الصفحة 1
الصفحة 1
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Mass Vaccination : Global Aspects - Progress and Obstacles

Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.

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Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals

Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals is a comprehensive handbook on all aspects of adverse effects by drugs and chemical substances on the kidneys.

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Clinical applications of mass spectrometry in drug analysis : Methods and protocols

This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

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Chirurgie esthétique et fonctionnelle de la face = Cosmetic and functional facial surgery

Cet ouvrage centré sur la chirurgie esthétique faciale repose sur une profonde connaissance de l'anatomie, de la physiologie et de l'étiopathogénie du vieillissement de la face. Les solutions thérapeutiques à visée esthétique sont développées mais en préservant toujours la fonction - gage d'un meilleur résultat immédiat et à plus long terme. Après un rappel du vieillissement cutané et de l'intérêt de l'utilisation de la toxine botulique, les aspects de la chirurgie esthétique de la face sont abordés à travers quatorze chapitres

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Botulinum Toxin in Aesthetic Medicine

This is an excellent resource for learning how to inject Botox. Even if you are a seasoned injector, I am sure you will discover tips to improve your technique. … The audience includes any physicians who use Botox in their practice. The book specifically focuses on cosmetic use of Botox, so plastic surgeons and dermatologists would be the majority of physicians interested in reading it.

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Botulinum toxin

Offering a step-by-step, practical approach to this commonly performed cosmetic procedure, Procedures in Cosmetic Dermatology: Botulinum Toxin, 5th Edition, enables you to master the up-to-date cosmetic techniques that produce the superior results your patients expect. It covers the science behind these neuromodulators and their usage areas in cosmetic dermatology, as well as the latest treatment options—all abundantly illustrated and evidence based. A substantial video library demonstrating injection techniques helps you successfully incorporate the latest procedures into your practice.

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Biotic elicitors: Production, purification, and characterization

Details techniques to study biotic elicitors involved in the field of agriculture for the benefit of the environment and growers. Chapters guide readers through protein, carbohydrate, lipid, glycoprotein and glycolipid components derived from microorganisms and their production, purification, and characterization.

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Biological nitrogen fixation, sustainable agriculture and the environment ; Proceedings of the 14th International nitrogen fixation congress

Covers aspects of fundamental and applied nitrogen-fixation research, from biochemistry and chemistry through genetics, regulation and physiology to agricultural practice and environmental impact. This work describes progress on studies of potential catalysts for nitrogen fixation; how the N2-fixing process is regulated in living cells; and more.

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Barile's clinical toxicology : Principles and mechanisms ; 3rd ed.

Examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. Special emphasis is placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs. Includes the source, pharmacological and toxicological mechanism of action, detection and identification in body fluids, and treatment of exposure. An overview of protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology, are discussed. In addition, effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered

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Bacterial virulence factors and Rho GTPases

The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.

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Associative and endophytic nitrogen-fixing bacteria and cyanobacterial associations

Associative and Endophytic Nitrogen-fixing Bacteria and Cyanobacterial Associations This book is part of the seven-volume series that was launched a few years ago with the ambitious objectives of reviewing the field of nitrogen fixation from its earliest beginnings through the millennium change and of consolidating the relevant information - from fundamental to agricultural and environmental aspects – all in one place. Volume 5 covers the biology of bacteria that associate with n- leguminous plants. The subject matter includes a wide range of associations; it covers the bacterial species that associate either with the surface or within the tissues of grasses (often referred as plant growth-promoting rhizobacteria) and also the symbiotic associations that cyanobacteria form with fungi, algae, and both lower and higher plants. This volume does not deal with the Frankia-actinorhizal plant associations, which is the topic of Volume 6

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Arzneimittel, giftstoffe, kunststoffe, farbstoffe, pestizide = Pharmaceuticals, toxins, plastics, dyes, pesticides

Spells out which methods in which cases produce the most comprehensive results. Beschreibt alle modernen Spektroskopiemethoden in Theorie und Praxis. Behandelt die schnelle und effektive Identifikation von Giftstoffen. Enthält zahlreiche Absorptions- und Massenspektren aus der Zentralkartei der Bayer AG.

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Antiviral drug discovery and development

Summarizes antiviral drug design and discovery approaches Provides the latest update in the field of antiviral therapeutics Includes antiviral research of coronaviruses

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Antibiotic Policies : Fighting Resistance

This book addresses many of the key issues taxing our society and hospitals in an era of epidemic resistance and shortage of new antibiotics. Written by internationally renowned experts in the field, this volume will provide practical advice and inform control strategies for the most urgent of problems related to antibiotic resistance epidemic for years to come. Antibiotic Policies: Fighting Resistance is an ideal volume for health professionals with an interest in this field.

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Algal Toxins : Nature, Occurrence, Effect and Detection

This volume contains the lectures and seminars given at the NATO Advanced Study Institute on “Sensor Systems for Biological Threads: The Algal Toxins Case”, held in Pisa, Italy in October, 2007. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.

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Algal Toxins : Nature, Occurrence, Effect and Detection

This volume contains the lectures and seminars given at the NATO Advanced Study Institute on “Sensor Systems for Biological Threads: The Algal Toxins Case”, held in Pisa, Italy in October, 2007. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.

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Agricultural Biotechnology in China : Origins and Prospects

Building on a long tradition of agricultural advances, Chinese scientists have applied biotechnology techniques to develop hundreds of novel crop varieties suited to local farming conditions and challenges.Agricultural Biotechnology in China: Origins and Prospects is a comprehensive examination of how the origins of biotechnology research agendas, along with the effectiveness of the seed delivery system and biosafety oversight, help to explain current patterns of crop development and adoption in China. Based on firsthand insights from China’s laboratories and farms, Valerie Karplus and Dr. Xing Wang Deng explore the implications of China’s investment for the nation’s rural development, environmental footprint, as well as its global scientific and economic competitiveness.

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Advances in multiple Sclerosis and Experimental Demyelinating Diseases

Challenging Charcot’s hypothesis that inflammatory response is the primary contributor to demyelination, Dr. Rodriguez and colleagues take a fresh, bold look at the causes and possible treatments of MS.Assuming oligodendrocyte injury as a prerequisite to MS, the authors explore viruses, toxins and genetic defects as possible culprits. They present novel methods to interrupt and reverse demyelination. This book examines the correlation between axonal loss and clinical deficits, including the implied role of the CD8+ T cell and perforin. It assesses proteases, specifically, kallikrein 6, which are strongly associated with active demyelination. By directing natural autoantibodies against oligodendrocytes that demonstrate remyelination in animal models, the authors envision clinical trials for remyelination enhancement.

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A History of Limb Amputation

This book traces humanity’s long experience of natural amputations due to congenital absence, disease, frostbite, toxins, domestic and wild animal trauma, and for non-medical reasons related to punitive, ritual, and legal actions, ultimately leading to the development of elective surgical amputation. While the evolution of surgical techniques forms a major chapter in the book, many ancillary problems are addressed including the control of hemorrhage and infection, the approach to pain relief, the development of suitable instruments and equipment, and the invention of prostheses, all suitably illuminated with case histories and relevant illustrations. In addition, alternative procedures designed to avoid amputation, increasingly important in the last two centuries, are debated, and factors associated with self-amputation in extremis, not rare according to press reports, are also examined. A separate chapter considers the philosophy and interpretations of society, patients, and surgeons faced with amputation, particularly before anesthesia.

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Architecture of advanced numerical analysis systems: designing a scientific computing system using ocaml

Applies the functional OCaml programming language to numerical or computational weighted data science, engineering, and scientific applications. This book is based on the authors' first-hand experience building and maintaining Owl, an OCaml-based numerical computing library. You'll first learn the various components in a modern numerical computation library. Then, you will learn how these components are designed and built up and how to optimize their performance. After reading and using this book, you'll have the knowledge required to design and build real-world complex systems that effectively leverage the advantages of the OCaml functional programming language.

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