May 12,2018 البحث العلمي والدراسات العليا, الصيدلة

Prevalence of Herpes Simplex Virus (Types 1 and 2), Varicella-Zoster Virus, Cytomegalovirus, and Human Herpesvirus 6 and 7 DNA in Cerebrospinal Fluid of Middle Eastern Patients with Encephalitis

Author

Ali I. Ibrahim; Michel T. Obeid; Muhidien J. Jouma; Klaus Roemer; Nikolaus Mueller-Lantzsch; Barbara C. Gärtner

Published in

Journal of Clinical Microbiology, Volume 43, Issue 8, August 2005

Abstract

HSV-1 DNA was detected in 32 (30%) of 106 cerebrospinal fluid samples from patients with encephalitis. Cytomegalovirus, varicella-zoster virus, and human herpesvirus 6 (HHV-6) DNAs were each detected in three patients (3%); herpes simplex virus type 2 (HSV-2) and HHV-7 PCRs were negative. HSV detection was associated with seizure (P = 0.02), especially focal seizure (P = 0.0002), and pathological computed tomography (P = 0.02) with focal lesions (P = 0.0004).

Link to read full paper

https://doi.org/10.1128/JCM.43.8.4172-4174.2005