Chemogenomics : Methods and protocols
- المؤلف
- Daniel Merk and Apirat Chaikuad
- سنة النشر
- 2023
- الناشر
- Springer
- لغة الملف
- انكليزي
- نوع الملف
- Book
- تصنيف الكتاب
- Medical Science
- تحميل الكتاب قراءة الكتاب
Presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; functional and target engagement assays in cellular settings for broad characterization; and a discussion on phenotypic assays where chemogenomic sets may be applied.
الكلمات المفتاحية: Pharmacology / Toxicology / Chemogenomics / Pharmacogenetics - Methods / Combinatorial chemistry techniques - Methods / Drug compounding - Methods / Chémogénomique / Pharmacogenetics methods / Druggable human proteome / Target validation / Annotated chemogenomic compounds / Targeted chemical libraries / Novel drugs / Drug targets / Genetics and genomics
