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One-Dimensional Nanostructures

One-dimensional (1D) nanostructures, including nanowires, nanotubes and quantum wires, have been regarded as the most promising building blocks for nanoscale electronic and optoelectronic devices. Worldwide efforts in both the theory and the experimental investigation of growth, characterization and applications of 1D nanostructures have resulted in a mature, multidisciplinary field. In this book, a wealth of state-of-the-art information offers the opportunity to uncover the underlying science from diverse perspectives. Leading researchers elucidate the synthesis and properties of 1D nanostructures for various morphologies and compositions (semiconductor, metal, carbon, etc.) as well as their considerable impact on spintronics, information storage, and the design of field-effect transistors.

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Nuucleic acids in medicinal chemistry and chemical biology : Drug development and clinical applications

Delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field

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Numerical analysis

Introduces readers to the theory and application of modern numerical approximation techniques. Providing an accessible treatment that only requires a calculus prerequisite, the authors explain how, why, and when approximation techniques can be expected to work-and why, in some situations, they fail. A wealth of examples and exercises develop readers' intuition, and demonstrate the subject's practical applications to important everyday problems in math, computing, engineering, and physical science disciplines.

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Nonlinear Problems of Elasticity

This second edition is an enlarged, completely updated, and extensively revised version of the authoritative first edition. It is devoted to the detailed study of illuminating specific problems of nonlinear elasticity. The mathematical tools from nonlinear analysis are given self-contained presentations where they are needed. This book begins with chapters on (geometrically exact theories of) strings, rods, and shells, and on the applications of bifurcation theory and the calculus of variations to problems for these bodies. The book continues with chapters on tensors, three-dimensional continuum mechanics, three-dimensional elasticity, large-strain plasticity, general theories of rods and shells, and dynamical problems. Each chapter contains a wealth of interesting, challenging, and tractable exercises.

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New and Evolving Infections of the 21st Century

This new volume of the Emerging Infectious Diseases of the 21st Century Series, has complied a collection of chapters by leading authorities of the world on emerging & evolving infections that is a must read for anyone interested in this topic. The chapters by reknown experts have provided a wealth of up-date information, such as clinical spectrum of disease, epidemiology, pathogenesis, diagnosis, management, prevention and future research.

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Neuroacanthocytosis Syndromes

Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.

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Neural Networks : Computational Models and Applications

Neural Networks: Computational Models and Applications covers a wealth of important theoretical and practical issues in neural networks, including the learning algorithms of feed-forward neural networks, various dynamical properties of recurrent neural networks, winner-take-all networks and their applications in broad manifolds of computational intelligence: pattern recognition, uniform approximation, constrained optimization, NP-hard problems, and image segmentation. By presenting various computational models, this book is developed to provide readers with a quick but insightful understanding of the broad and rapidly growing areas in the neural networks domain. Besides laying down fundamentals on artificial neural networks, this book also studies biologically inspired neural networks. Some typical computational models are discussed, and subsequently applied to objection recognition, scene analysis and associative memory. The studies of bio-inspired models have important implications in computer vision and robotic navigation, as well as new efficient algorithms for image analysis.

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Mutual Funds : Fifty Years of Research Findings

"This book presents an outstanding wealth of information on mutual funds in a remarkably readable format. It is probably the most comprehensive work currently available on funds. The book sheds light on the numerous issues surrounding mutual fund performance and pricing and is an important resource for any serious investor."

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Multiple Integrals in the Calculus of Variations

From the reviews: "…the book contains a wealth of material essential to the researcher concerned with multiple integral variational problems and with elliptic partial differential equations. The book not only reports the researches of the author but also the contributions of his contemporaries in the same and related fields. The book undoubtedly will become a standard reference for researchers in these areas. …The book is addressed mainly to mature mathematical analysts. However, any student of analysis will be greatly rewarded by a careful study of this book."

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Multimedia security : Algorithm development, analysis and applications (algorithms for intelligent systems)

Provides an insight about various techniques used in multimedia security and identifies its progress in both technological and algorithmic perspectives. In the contemporary world, digitization offers an effective mechanism to process, preserve and transfer all types of information. The incredible progresses in computing and communication technologies augmented by economic feasibility have revolutionized the world. The availability of efficient algorithms together with inexpensive digital recording and storage peripherals have created a multimedia era bringing conveniences to people in sharing the digital data that includes images, audio and video. The ever-increasing pace, at which the multimedia and communication technology is growing, has also made it possible to combine, replicate and distribute the content faster and easier, thereby empowering mankind by having a wealth of information at their disposal.

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Mucosal Immunology and Virology

Mucosal Immunology and Virology is designed to provide the clinician with a thorough and yet approachable textbook describing the relationships between immunology, virology and the disease process. It includes a vast wealth of information and illustrations to enable the reader to become familiar with the clinical presentation of these diseases, the tests needed to establish the diagnosis, and the treatment of the disease including specific antiviral agents. Suitable for residents and clinicians in immunology, infectious diseases, internal medicine and dermatology the book reviews the systematic manifestations of mucosal viral infections, including those involving the mouth, gastrointestinal tract, respiratory system, anogenital mucosa and ocular infections

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Molecular Mechanisms of Neurotransmitter Release

Within the complex neuronal network of the nervous system, neuron-to-neuron communication occurs mainly through chemical synapses, where the presynaptic nerve terminal releases neurotransmitters that control the function of postsynaptic neurons by acting on postsynaptic receptors. Recent decades have brought groundbreaking new developments and a wealth of knowledge to this field. In Molecular Mechanisms of Neurotransmitter Release, leading experts provide concise, up-to-date information on all major molecular mechanisms involved, with complete background information and figures and diagrams to further elucidate key concepts or experiments.Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release is sure to provide a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for all those who have a general interest in the ever-evolving field of neuroscience.

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Modern luminescence spectroscopy of minerals and materials

Luminescence Spectroscopy of Minerals and Materials presents an overview of the general concepts in luminescence spectroscopy as well as experimental methods and their interpretation. Special emphasis is laid on the fluorescence lifetime and the determination of time-resolved spectra. This method enables the exposure of new luminescence in minerals previously hidden by more intensive centers. Specialists in the fields of solid state physics, chemistry and spectroscopy will find a wealth of new information in this unique book.

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Modern asset allocation for wealth management

This book provides a complete taxonomy of modern methods for constructing investment portfolios. It goes beyond the simplest models and heuristics that are commonly used today and brings advances that are otherwise buried in Ph.D.-level mathematics to the financial advisor community. It covers all aspects of creating client portfolios, including choosing asset classes to invest in, selecting securities within asset classes, client risk preference assessment, portfolio construction, and portfolio rebalancing.

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Medicinal plants of the world ; Vol.3 : Chemical constituents, traditional and modern medicinal uses

The author's exhaustive summary of available scientific data for each plant provides detailed information on how the plant is used in different countries, describing its traditional therapeutic applications and what is known from its use in clinical trials. Additional material presented includes a botanical description with a color photo of each plant for identification, the common names used for the plant throughout the world, and a listing of the plant's known chemical constituents. A comprehensive bibliography cites the literature available from a wide range of disciplines. Medicinal Plants of the World: Chemical Constituents, Traditional and Modern Medicinal Uses, Volume 3, offers a unique collection of vital scientific information for pharmacologists, herbal medicine practitioners, drug developers, phytochemists, medicinal chemists, phytologists, toxicologists, and researchers who want to explore the many uses of plant materials for medicinal and related purposes. Its wealth of significant information will reveal little-known facts about these plants and open new horizons of application for the many novel drugs and drug candidates found in them.

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Mechanisms of Angiogenesis

Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.

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Measurement Errors and Uncertainties : Theory and Practice

Measurement Errors and Uncertainties addresses the most important problems that physicists and engineers encounter when estimating errors and uncertainty. Building from the fundamentals of measurement theory, the author develops the theory of accuracy of measurements and offers a wealth of practical recommendations and examples of applications.

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Maxillofacial Imaging

Demonstrates how advanced medical imaging techniques can be successfully applied to dental and maxillofacial conditions. There is a focus on CT and MRI, but the use of all contemporary imaging techniques are illustrated including PET, PET/CT, ultrasonography, and cone beam CT. The presentation is in atlas style, with succinct, bulleted text and a wealth of high-quality images in multiple planes. All images for each patient are grouped to enable the reader very quickly to gain an imaging overview of the condition under consideration. After a comprehensive introductory chapter on normal imaging anatomy, the role of advanced imaging techniques is described in pathologic conditions of the mandible and maxilla, temporomandibular joint, regions closely related to the jaw, paranasal sinuses, oral cavity, salivary glands, and structures adjacent to the maxillofacial region. A concluding chapter examines the use of interventional procedures for diagnosis and treatment of maxillofacial conditions. Compared with the first edition, numerous additional cases have been incorporated and a completely new chapter focuses on cone beam CT.

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Matter and Methods at Low Temperatures

Matter and Methods at Low Temperatures contains a wealth of information essential for successful experiments at low temperatures, which makes it suitable as a reference and textbook. This third edition also describes newly developed low-temperature experimentation techniques and new materials properties; it also contains many additional references and a list of suppliers of cryogenic equipment.

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Interconnect Noise Optimization in Nanometer Technologies

The authors bring together a wealth of information presenting a range of CAD algorithms and techniques for synthesizing and optimizing interconnect. Practical aspects of the algorithms and the models are explained with sufficient details. The book investigates the most effective parameters in layout optimization. Different post-layout optimization techniques with complexity analysis and benchmarks tests are provided. The impact crosstalk noise and coupling on the wire delay is analyzed. Parameters that affect signal integrity are also considered.

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