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Ondansetron Patches

The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.

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Object-Oriented Programming Languages : Interpretation

This comprehensive examination of the main approaches to object-oriented language explains the key features of the languages in use today. Class-based, prototypes and Actor languages are all looked at and compared in terms of their semantic concepts. In providing such a wide-ranging comparison, this book provides a unique overview of the main approaches to object-oriented languages.

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Numerical Continuation Methods for Dynamical Systems : Path following and boundary value problems

The book opens with a foreword by Herbert B. Keller and lecture notes by Sebius Doedel himself that introduce the basic concepts of numerical bifurcation analysis. The other chapters by leading experts discuss continuation for various types of systems and objects and showcase examples of how numerical bifurcation analysis can be used in concrete applications. Topics that are treated include: interactive continuation tools, higher-dimensional continuation, the computation of invariant manifolds, and continuation techniques for slow-fast systems, for symmetric Hamiltonian systems, for spatially extended systems and for systems with delay. Three chapters review physical applications: the dynamics of a SQUID, global bifurcations in laser systems, and dynamics and bifurcations in electronic circuits.

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Nuclear Energy : Principles, Practices, and Prospects

The world faces serious difficulties in obtaining the energy that will be needed in coming decades for a growing population, especially given the problem of climate change caused by fossil fuel use. This book presents a view of nuclear energy as an important carbon-free energy option. It discusses the nuclear fuel cycle, the types of reactors used today and proposed for the future, nuclear waste disposal, reactor accidents and reactor safety, nuclear weapon proliferation, and the cost of electric power. To provide background for these discussions, the book begins with chapters on the history of the development and use of nuclear energy, the health effects of ionizing radiation, and the basic physics principles of reactor operation. The text has been rewritten and substantially expanded for this edition, to reflect changes that have taken place in the eight years since the publication of the first edition and to provide greater coverage of key topics. These include the Yucca Mountain repository plans, designs for next-generation reactors, weapons proliferation and terrorism threats, the potential of alternatives to nuclear energy, and controversies about low-level radiation.

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Noise-Induced Transitions : Theory and Applications in Physics, Chemistry, and Biology

This classic text, an often-requested reprint, develops and explains the foundations of noise-induced processes. At its core is a self-contained, textbook-style presentation of the elements of probability theory, of the theory of Markovian diffusion processes and of the theory of stochastic differential equations, on which the modeling of fluctuating natural and artificial environments is based. Following an introduction to the mathematical tools, the occurrence and the properties of noise-induced transitions are then analyzed for rapidly fluctuating environments describable by the white-noise idealization. Subsequently, more realistic and general types of colored noises are considered. Appropriate practical methods for dealing with these situations are developed. The latter part of the book contains applications and experimental studies illustrating the many facets of noise-induced transitions. The following applications are considered in Noise-Induced Transitions: population dynamics, electrical circuits, chemical and photochemical reactions, non-linear optics, and hydrodynamical systems.

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New Vision of Metformin in treating cancer

The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.

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New technical approaches and medications to improve fertility for women in Syria

Egg freezing is one way of preserving a woman's fertility so she can try to have a family in the future. It involves collecting a woman's eggs, freezing them and then thawing them later on so they can be used in fertility treatment. Egg freezing won't lower your ovarian reserve and won't decrease your chances of getting pregnancy naturally in the future. To understand why, we will first of all focus on the ovulation process. During each menstrual cycle—typically each month—one egg makes it through the whole ovulatory process, and we will discuss all the reasons which may suggest to do such a specific process in women such as being in malignant diseases and the risk of its side effects of this therapy on fertility for example this medication or radiation therapy mainly in a abdomen area is reducing fertility beside other types of medications mentioned in this research

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New Materials in Civil Engineering

A valuable guide to the properties, selection criteria, products, applications, lifecycle and recyclability of advanced materials. It presents an A-to-Z approach to all types of materials, highlighting their key performance properties, principal characteristics and applications. Traditional materials covered include concrete, soil, steel, timber, fly ash, geosynthetic, fiber-reinforced concrete, smart materials, carbon fiber and reinforced polymers. In addition, the book covers nanotechnology and biotechnology in the development of new materials.

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Neural networks and deep learning

Covers both classical and modern models in deep learning. The primary focus is on the theory and algorithms of deep learning. The theory and algorithms of neural networks are particularly important for understanding important concepts, so that one can understand the important design concepts of neural architectures in different applications. Why do neural networks work? When do they work better than off-the-shelf machine-learning models? When is depth useful? Why is training neural networks so hard? What are the pitfalls? The book is also rich in discussing different applications in order to give the practitioner a flavor of how neural architectures are designed for different types of problems.

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Network Science, Nonlinear Science and Dynamic Game Theory Applied to the Study of Infrastructure Systems

Network Science, Nonlinear Science and Infrastructure Systems has been written by leading scholars in these areas. Its express purpose is to develop common theoretical underpinnings to better solve modern infrastructural problems. It is felt by many who work in these fields that many modern communication problems, ranging from transportation networks to telecommunications, Internet, supply chains, etc., are fundamentally infrastructure problems. Moreover, these infrastructure problems would benefit greatly from a confluence of theoretical and methodological work done with the areas of Network Science, Dynamical Systems and Nonlinear Science. This book is dedicated to the formulation of infrastructural tools that will better solve these types of infrastructural problems.

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Nanotechnology for Oral Drug Delivery : From Concept to Applications

Discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance.

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Nanoformulations in Human Health: Challenges and Approaches

This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.

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Multi-Source National Forest Inventory : Methods and Applications

The book describes in detail the full MS-NFI process, and the input data used – including field data, satellite images, and digital map data, as well as coarse-scale variation of forest variables. It also presents comprehensive information on the types of outputs which can be derived, including maps and statistics, describing, for example, stock volumes and development, dominant tree species, age-class distribution, and large and small-scale variation. The book will provide an invaluable resource for those involved in forest inventory, including government departments and bodies involved in forest policy, management and monitoring, forest managers, and researchers and graduate students interested in forest inventory, modelling and analysis. It will find an additional market among those interested in Earth observation, ecology and broader areas of environmental and natural resource management.

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Multimedia security : Algorithm development, analysis and applications (algorithms for intelligent systems)

Provides an insight about various techniques used in multimedia security and identifies its progress in both technological and algorithmic perspectives. In the contemporary world, digitization offers an effective mechanism to process, preserve and transfer all types of information. The incredible progresses in computing and communication technologies augmented by economic feasibility have revolutionized the world. The availability of efficient algorithms together with inexpensive digital recording and storage peripherals have created a multimedia era bringing conveniences to people in sharing the digital data that includes images, audio and video. The ever-increasing pace, at which the multimedia and communication technology is growing, has also made it possible to combine, replicate and distribute the content faster and easier, thereby empowering mankind by having a wealth of information at their disposal.

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Multimedia Introduction to Programming Using Java

Although vital to modern software development, Java and object-oriented programming can pose significant challenges to newcomers. This text, unique in both scope and approach and accompanied by interactive content that you may find on extras.springer.com, addresses that learning curve by providing a careful, classroom-tested presentation of Java -- from the fundamentals of variables, types, and expressions to procedural concepts like loops and sophisticated object-oriented ideas. Additional key features of this work Introduces objects and classes early in the exposition, rendering object-oriented programming intuitive and natural. Develops programs, rather than simply showcasing them. Supports all concepts through complementary lectures on the zip-file featured on extras.springer.com. Contains numerous self-help exercises that encourage readers to practice programming. With its comprehensive appendices and bibliography, systematic approach, and helpful interactive programs on extras.springer.com, this exciting work provides the key tools they needed for successful object-oriented programming. It is ideal for use at the undergraduate and graduate beginning level, whether in the classroom or for distance learning; furthermore, the text will also be a valuable self-study resource or reference volume in any programmer’s library.

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Multilayered Low Temperature Cofired Ceramics (LTCC) Technology

LTCCs are made by combining ceramic insulating materials, conductor materials, and other materials through numerous processes culminating in co-firing. The materials and the processes used are therefore interdependent. By ensuring the consistency between materials and processes, it is possible to achieve circuit boards and various types of high frequency passive components and so on with the desired characteristics. This book describes the general technical information of each material (ceramic, conductor, and resistor materials) and each process, and it offers commentaries on unique examples resulting from these interrelations.

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Multi-Agent Systems and Applications IV ; 4th International Central and Eastern European Conference on Multi-Agent Systems, CEEMAS 2005, Budapest, Hungary, September 15-17, 2005, Proceedings

In the very competitive field of agent oriented conferences and workshops nowadays (such as AAMAS, WI/IAT, EUMAS, CIA, MATES) the special profile of CEEMAS is that it is trying to bridge the gap between applied research achievements and theoretical research activities. Our ambition is to provide a forum for presenting theoretical research with an evident application potential, implemented application prototypes and their properties, as well as industrial case studies of successful (but also unsuccessful) agent technology deployments. This is why the CEEMAS proceedings volume provides a collection of research and application papers. The technical research paper section of the proceedings (see pages 11–499) contains pure research papers as well as research results in application settings while the application papers section (see pages 500–530) contains papers focused on application aspects. The goal is to demonstrate the real life value and commercial reality of multi-agent systems as well as to foster communication between academia and industry in this field.

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MSC Maximal Stress Cooperation

In 1996 my book ‘The Nature of Cultures’ appeared in Vi- na and New York. It describes cultures as systems which are controlled by MSC and decorum. While MSC is a neologism meaning ‘maximal stress cooperation’ decorum is a very old term. It is as old as Western culture itself, and is furthermore, the translation of the even older Greek word ‘prepon’. Decorum and prepon mean ‘to be suitable, to be fitting’. It is all about the fitting of cultural medial contents to elementary cultural behavioural types and behavioural phases. These behavioural units are subject to a type of ranking system in which that which is essential is sorted from that which less essential. - corum then means – the representations of the media must ‘fit’ the ranking of the cultural behaviour. It is MSC which assumes the top position in this ranking. In 1996 and the two previous years when I was working on my book ‘The Nature of Cultures’ less than 5 years had passed since the Iron Curtain had been lifted. Many believed at that time that with ending of the Cold War, which was more or less de facto peace anyway, that a new and better age of peace was dawning.

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Mouse Models of Human Blood Cancers : Basic Research and Pre-clinical Applications

Although it remains an open question among some people whether mice and humans are similar in disease development, the laboratory mouse has emerged as the preeminent animal model for human diseases. This is underscored by the recently completed mouse and human genome projects, which have revealed that mice and humans share the vast majority of their genes, and thus get many of the same diseases, and for the same reasons. Emphasizing why mouse models are valuable in vivo systems for understanding disease mechanisms and developing therapeutic strategies for human blood cancers, "Mouse Models of Human Blood Cancers: Basic Research and Pre-clinical Applications," edited by Shaoguang Li, aims on presenting thorough analyses of the pathological features and the molecular bases of several major types of blood cancer and to describe translational research using mouse cancer models.

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Mortality and Maldevelopment : Part I : Congenital cardiovascular malformations

The most frequent of them all are the many types of malformations of the cardiovascular system, the heart and its blood vessels.Study of these conditions during the twentieth century took many forms, revolving about examination and analysis of their causes, genetic, nongenetic, and complex. To aid in unraveling the complexities of this causation, various influences on their frequency are considered, among them social conditions, maternal health, birthweight, newborn maturity. And of course the known and possible environmental bases of their occurrence are fully described.

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