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One hundred years of social protection : The changing social question in Brazil, India, China, and South Africa
As the first in-depth study of the ideational foundations of social protection policies and programmes in these four countries, the contributions demonstrate that the social question was articulated in an increasingly inclusive way.
Ondansetron Patches
The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.
On the Topology of Isolated Singularities in Analytic Spaces
The aim of this book is to give an overview of selected topics on the topology of real and complex isolated singularities, with emphasis on its relations to other branches of geometry and topology. The first chapters are mostly devoted to complex singularities and a myriad of results spread in a vast literature, which are presented here in a unified way, accessible to non-specialists. Among the topics are the fibration theorems of Milnor; the relation with 3-dimensional Lie groups; exotic spheres; spin structures and 3-manifold invariants; the geometry of quadrics and Arnold's theorem which states that the complex projective plane modulo conjugation is the 4-sphere. The second part of the book studies pioneer work about real analytic singularities which arise from the topological and geometric study of holomorphic vector fields and foliations. In the low dimensional case these turn out to be related to fibred links in the 3-sphere defined by meromorphic functions. This provides new methods for constructing manifolds equipped with a rich geometry.
olution Sets for Net Zero Energy Buildings : Feedback from 30 Buildings Worldwide
Presents a unique study of 30 NZEBs that have been constructed and have had their performance measured for at least 12 months. The study is based upon an international collaborative research initiated by the International Energy Agency. It is the first book to evaluate building strategies in houses, educational buildings and offices that have been demonstrated to work in practice. It examines how the design challenges of climate and building type have been addressed, and to what extent the various design approaches have been successful. This book presents convincing evidence that a careful re-thinking of conventional design norms can achieve a far greater performance benefit than is normally feasible. It identifies 'solution sets' that work at the whole building level and at the individual building design challenge level for each climate and building type. In doing so, the book provides guidance as to how to improve the design by learning from these cases. Unusually for a book of this type it has examples of buildings in what are conventionally labeled 'hot' and 'cold' climates.
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Ocean Waves Breaking and Marine Aerosol Fluxes
This book presents a comprehensive study on the breaking of surface waves induced by wind and the relationship of breaking rate with marine aerosol fluxes. The book draws attention to the theoretical and experimental achievements in the study of wave breaking phenomena in deep water seas. In particular, it deals with the important problems of energy dissipation and the estimation of energy loss due to wave breaking in deep waters. The rationale behind existing methods and practical outcomes for the estimation of whitecap coverage of the sea surface and energy dissipation rate are given in detail.The book also focuses on the fundamentals of marine aerosols and their generation. The text provides a comprehensive overview of the currently available experimental data on marine aerosol fluxes and presents theoretical methodology of the estimation of the intensity of sea aerosol production. The systematic analysis leads to a novel approach in the development of links between aerosol production with sea state parameters and its seasonal variation in deep water seas.
Object-Oriented Software Engineering Using UML Patterns and Java
Shows students how to use both the principles of software engineering and the practices of various object-oriented tools, processes, and products. Using a step-by-step case study to illustrate the concepts and topics in each chapter, Bruegge and Dutoit emphasize learning object-oriented software engineer through practical experience: students can apply the techniques learned in class by implementing a real-world software project. The third edition addresses new trends, in particular agile project management (Chapter 14 Project Management) and agile methodologies (Chapter 16 Methodologies).
Obesity and Cancer
This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development.
Nutraceuticals and health care ; 1st ed.
Explores the role of plant-based nutraceuticals as food ingredients and as therapeutic agents for preventing various diseases. The book assesses the role of nutraceuticals in addressing cardiovascular disease, cancer, diabetes, and obesity by highlighting the derivatives, extraction, chemistry, mechanism of action, pharmacology, bioavailability, and safety of specific nutraceuticals. It analyzes twenty one nutraceuticals in a systematic way, providing a welcomed reference for nutrition researchers, nutritionists and dieticians, as well as other scientists studying related areas in food science, technology or agriculture. Students studying related topics will also benefit from this material.
Nutraceuticals : Sources, processing methods, properties, and applications
Explores the impact of nutraceutical compounds on human health and their main pharmacological contributions. Organized into three parts, this book addresses nutraceutical production, applications for disease prevention and treatment, and current trends, especially the role of nutraceuticals in cosmeceutical. Nutraceuticals are a class of products that can help people improve their health, reduce the risk of disease, extend their lives, and control the structure and functioning of their bodies. However, due to multiple hurdles that prevent nutraceuticals from circulating in an active form in the body, their use is associated with diminished therapeutic efficacy. Recognizing this problem, the book explores the root of the nutraceutical delivery system and its codelivery methods with a focus on medicines. With contributions from experienced nutraceutical experts, this book serves as a valuable reference for nutrition researchers, food scientists, pharmacologists, and those who are researching and studying in related areas.
Numerical Simulation of Mechatronic Sensors and Actuators
The second edition of this book fully preserves the character of the first edition to combine the detailed physical modeling of mechatronic systems and their precise numerical simulation using the Finite Element (FE) method. Most of the text and general appearance of the previous edition were retained, while the coverage was extended and the presentation improved. A large part of the book describes the application of the developed numerical calculation schemes to industrial problems, e.g.: analysis and optimization of electrodynamic loudspeakers. In these parts, new computational methods are included, and last but not least, this new edition contains a new chapter on computational aeroacoustics to study the complex phenomenon of flow induced noise.
Numerical Linear Algebra
This book brings together linear algebra, numerical methods and an easy to use programming environment under Matlab (or Scilab). One of the key features of the book are the worked out examples and exercises at the end of each chapter. The reader is asked to do some numerical experiments in Matlab and then to prove the results theoretically. The book is a combination and update of two earlier French books by the authors. It is appropriate for both undergraduate and beginning graduate courses in mathematics as well as for working scientists and engineers as a self-study tool and reference.This book is about numerical linear algebra and focuses on practical algorithms for solving computer problems of linear algebra.
Nuclear Import and Export in Plants and Animals
Nuclear Import and Export in Plants and Animals provides insight into the remarkable mechanisms of nuclear import and export. This book covers a range of topics from the nuclear pore structure, to nuclear import and export of macromolecules in plant and animal cells. In addition, the book covers the special cases of nuclear import of Agrobacterium T-DNA during plant genetic transformation, nuclear import and export of animal viruses, and nuclear intake of foreign DNA. A chapter on research methods to study nuclear transport concludes the book.
Novel Plant Imaging and Analysis : Water, Elements and Gas, Utilizing Radiation and Radioisotopes
This book is only an introduction to show that radiation and radioisotopes (RI) are premier tools to study living plant physiology which leads to new findings. Who had ever imagined that we could see water in a plant? Who had ever imagined that we could see ions moving toward roots in solution? Who had ever imagined that we could see invisible gas (CO2) fixation and movement in a plant? These studies demonstrated for the first time that water, ions and gas can be visualized in living plants, which could be hardly seen by anyone before. This publication summarizes the results obtained by Nakanishi’s lab in The Univ. of Tokyo, based on her original concept and her original tools or systems. It is useful for professional scientists, plant physiologist, and those studying plant imaging.
Notions of Convexity
The first two chapters of this book are devoted to convexity in the classical sense, for functions of one and several real variables respectively. This gives a background for the study in the following chapters of related notions which occur in the theory of linear partial differential equations and complex analysis such as (pluri-)subharmonic functions, pseudoconvex sets, and sets which are convex for supports or singular supports with respect to a differential operator. In addition, the convexity conditions which are relevant for local or global existence of holomorphic differential equations are discussed, leading up to Trépreau’s theorem on sufficiency of condition (capital Greek letter Psi) for microlocal solvability in the analytic category.
Northern Lights on Civic and Citizenship Education : A Cross-national Comparison of Nordic Data from ICCS
This book presents an in depth analysis of data from ICCS. An international group of scholars critically address the state of civic and citizenship education in the four Nordic countries that participated in the IEA International Civic and Citizenship Education Study (ICCS) in 2009 and 2016. The findings are of particular relevance to educators at all levels, from school education through to teacher education.
Nordic Mediation Research
Presents twelve unique studies on mediation from researchers in Denmark, Finland, Norway and Sweden, respectively. Each study highlights important aspects of mediation, including the role of children in family mediation, the evolution and ambivalent application of restorative justice in the Nordic countries, the confusion of roles in court-connected mediation, and the challenges in dispute systems.
Nonsmooth Vector Functions and Continuous Optimization
A recent significant innovation in mathematical sciences has been the progressive use of nonsmooth calculus, an extension of the differential calculus, as a key tool of modern analysis in many areas of mathematics, operations research, and engineering. Focusing on the study of nonsmooth vector functions, this book presents a comprehensive account of the calculus of generalized Jacobian matrices and their applications to continuous nonsmooth optimization problems and variational inequalities in finite dimensions.
Non-Native Language Teachers : Perceptions, Challenges and Contributions to the Profession
Now that non-natives are increasingly found teaching languages, and particularly English, both in ESL and EFL contexts, the identification of their specific contributions and their main strengths has become more relevant than ever.As a result, there has recently been a surge of interest in the role of non-native teachers but little empirical research has been published so far. This volume is particularly rich in providing different approaches to the study of non-native teachers: NNS teachers as seen by students, teachers, graduate supervisors, and by themselves. It also contributes little explored perspectives, like classroom discourse analysis, or a social-psychological framework to discuss conceptions of NNS teachers.
Nonlinear Time Series Analysis in the Geosciences : Applications in Climatology, Geodynamics and Solar-Terrestrial Physics
This book presents recent developments in nonlinear time series which have been motivated by present day problems in geosciences. Modern methods of spatio-temporal data analysis, time-frequency analysis, dimension analysis, nonlinear correlation and synchronization analysis and other nonlinear concepts are used to study emerging questions in climatology, geophysics, solar-terrestrial physics and related scientific disciplines. This volume collects contributions of some of the world's leading experts in geoscientific time series analysis.
