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Multichain Immune Recognition Receptor Signaling : From Spatiotemporal Organization to Human Disease

The central idea of this book is to show that the structural similarity of the MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms and also provides the basis for existing and fixture therapeutic strategies targeting MIRRs. The reviews assembled in this book detail the prog-ress in defining and controlling the spatiotemporal organization of key events in immune cell activation. An improved understanding of MIRR-mediated signaling has numerous potential practical applications, fi-om the rational design of drugs and vaccines to the engineering of cells for biotechnological purposes.

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Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy : Route to Femtosecond Ångstrom Technology

"Mono-Cycle Photonics and Optical Scanning Tunneling Microscopy" deals with both the ultrashort laser-pulse technology in the few- to mono-cycle region and the laser-surface-controlled scanning-tunneling microscopy (STM) extending into the spatiotemporal extreme technology. The former covers the theory of nonlinear pulse propagation beyond the slowly-varing-envelope approximation, the generation and active chirp compensation of ultrabroadband optical pulses, the amplitude and phase characterization of few- to mono-cycle pulses, and the feedback field control for the mono-cycle-like pulse generation. In addition, the wavelength-multiplex shaping of ultrabroadband pulse is described. The latter covers the CW-laser-excitation STM, the femtosecond-time-resolved STM and atomic-level surface phenomena controlled by femtosecond pulses.

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Mobility, data mining and privacy : Geographic knowledge discovery

This book assesses this research frontier from a computer science perspective, investigating the various scientific and technological issues, open problems, and roadmap. The editors manage a research project called GeoPKDD, Geographic Privacy-Aware Knowledge Discovery and Delivery, funded by the EU Commission and involving 40 researchers from 7 countries, and this book tightly integrates and relates their findings in 13 chapters covering all related subjects, including the concepts of movement data and knowledge discovery from movement data; privacy-aware geographic knowledge discovery; wireless network and next-generation mobile technologies; trajectory data models, systems and warehouses; privacy and security aspects of technologies and related regulations; querying, mining and reasoning on spatiotemporal data; and visual analytics methods for movement data.

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MDATA : A New Knowledge Representation Model: Theory, Methods and Applications

This book introduces a new knowledge representation model called MDATA (Multi-dimensional Data Association and inTelligent Analysis). By modifying the representation of entities and relations in knowledge graphs, dynamic knowledge can be efficiently described with temporal and spatial characteristics. The MDATA model can be regarded as a high-level temporal and spatial knowledge graph model, which has strong capabilities for knowledge representation. This book introduces some key technologies in the MDATA model, such as entity recognition, relation extraction, entity alignment, and knowledge reasoning with spatiotemporal factors. The MDATA model can be applied in many critical applications and this book introduces some typical examples, such as network attack detection, social network analysis, and epidemic assessment.

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Impulse Breakdown of Liquids

The book describes the main physical processes and phenomena in pulsed electric breakdown. The knowledge and the control of the electric breakdown of liquids is important not only for the insulation inside power systems but it is also used for the creation and information of high voltage and high current pulses. Such high-voltage micro- and nanosecond pulses find wide application in experimental physics, electro discharge technology, physics of dielectrics, radar detection and ranging, high-speed photography. The nature of charge carriers, mechanism of formation and evolution of the gas phase, and their role in charge ignition (initiation) and development are considered. In particular, the spatiotemporal laws of propagation and parameters of charge channels are described in detail and the boundery conditions of the breakdown initiation are formulated.

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Fuzzy Chaotic Systems : Modeling, Control, and Applications

"Fuzzy Chaotic Systems" provides original heuristic research achievements and insightful ideas on the interactions or intrinsic relationships between fuzzy logic and chaos theory. It presents the fundamental concepts of fuzzy logic and fuzzy control, chaos theory and chaos control, as well as thedefinition of chaos on the metric space of fuzzy sets. This monograph discusses and illustrates fuzzy modeling and fuzzy control of chaotic systems, synchronization, anti-control of chaos, intelligent digital redesign, spatiotemporal chaos and synchronization in complex fuzzy systems; as well as a practical application example of fuzzy-chaos-based cryptography. Like other very good books, this book may raise more questions than it can provide answers. It therefore generates a great potential to attract more attention to combine fuzzy systems with chaos theory and contains important seeds for future scientific research and engineering applications.

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Control of Spatially Structured Random Processes and Random Fields with Applications

This book is devoted to the study and optimization of spatiotemporal stochastic processes, that is, processes which develop simultaneously in space and time under random influences. These processes are seen to occur almost everywhere when studying the global behavior of complex systems.Classical stochastic dynamic optimization forms the framework of the book. Taken as a whole, the project undertaken in the book is to establish optimality or near-optimality for Markovian policies in the control of spatiotemporal Markovian processes. The authors apply this general principle to different frameworks of Markovian systems and processes. Depending on the structure of the systems and the surroundings of the model classes the authors arrive at different levels of simplicity for the policy classes which encompass optimal or nearly optimal policies. A set of examples accompanies the theoretical findings, and these examples should demonstrate some important application areas for the theorems discussed.

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