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Natural products and human diseases : Pharmacology, molecular targets, and therapeutic benefits

Provides insight into the clinical and translational application of natural products in human diseases Details the impact of natural products on a molecular basis Describes the identification of biomarkers, therapeutic effects of phytochemicals, and and new targets

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Monitors of Organic Chemicals in the Environment : Semipermeable Membrane Devices

Modern, industrialized societies depend on a wide range of chemical substances such as fuels, plastics, biocides, pharmaceuticals and detergents for maintaining the high quality lifestyle to which we aspire. The challenge is to ensure that while we enjoy the benetsof thes esubstances,theirinevitablereleaseintoourbiosphere does not result in unwanted human and ecosystem exposures, and the risk of - verse effects. One response to this challenge has been the extensive effort to detect and analyze or monitor a multitude of chemicals in a variety of environmental media, especially toxic organic compounds in air, water, soils and biota. An extensive literature on these traditional techniques has evolved over the years.

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Molecular Mechanisms of Synaptogenesis

Molecular Mechanisms of Synaptogenesis is a compilation of recent exciting findings that summarizes the ever-expanding knowledge of how neuronal contacts develop in the normal brain and how their functions are affected in mental disorders. In the last decade, advances in molecular and cellular biology, combined with the development of sophisticated fluorescence microscopy tools to visualize synapses in live neurons, have revealed many intriguing and unexpected findings regarding the dynamics of synapse formation. Studies by a number of researchers have identified several critical protein components of synapses and shown the time course of their arrival at the synapse. Several molecules serve to hold the synaptic contacts between nerve cells and regulate their function.

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mm-Wave Silicon Technology : 60 GHz and Beyond

mm-Wave Silicon Technology: 60GHz and Beyond covers silicon-based millimeter wave circuits and systems. It provides in depth coverage of advanced silicon processing technologies including CMOS and SiGe as well as modeling of active and passive devices on silicon at millimeter waves. It also provides coverage of mm-wave circuit building blocks such as low noise amplifiers, mixers, voltage controlled oscillators, frequency dividers, and power amplifiers that are suitable for integration in silicon. The book contains information on highly integrated mm-wave transceiver architectures with several silicon-based case studies. The book also includes advanced topics such as antenna arrays and beam-forming on silicon.

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Inherited inborn errors in amino acids metabolism

Proteins are the most abundant organic molecules in animals, playing important roles in all aspects of cell structure and function. Proteins are biopolymers of acids, so named because the amino group is bonded to the carbon atom, next to the carbonyl group.

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Information security and privacy ; 12th Australasian Conference, ACISP 2007, Townsville, Australia, July 2-4, 2007, Proceedings

The book covers a wide array of key aspects in information security. The papers are organized in topical sections on stream ciphers, hashing, biometrics, secret sharing, cryptanalysis, public key cryptography, authentication, e-commerce, and security.

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Foundations of Trusted Autonomy

This book establishes the foundations needed to realize the ultimate goals for artificial intelligence, such as autonomy and trustworthiness. Aimed at scientists, researchers, technologists, practitioners, and students, it brings together contributions offering the basics, the challenges and the state-of-the-art on trusted autonomous systems in a single volume. The book is structured in three parts, with chapters written by eminent researchers and outstanding practitioners and users in the field. The first part covers foundational artificial intelligence technologies, while the second part covers philosophical, practical and technological perspectives on trust. Lastly, the third part presents advanced topics necessary to create future trusted autonomous systems. The book augments theory with real-world applications including cyber security, defence and space.

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Foundations of AOP for J2EE Development

Foundations of AOP for J2EE Development covers a relatively new programming paradigm: aspect-oriented programming, or AOP. Presented are the core concepts of AOP: AspectJ 5, JBoss AOP, Spring AOP, and JAC. Specific features of these tools are compared. The book also explores the potential uses of AOP in everyday programming life, such as design patterns implementation, program testing, and application management. In the latter part of the book, the authors show how AOP can ease the task of J2EE application development (J2EE is known for being a rich and somewhat complicated framework).

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Fashionable Technology

The interplay of electronic textiles and wearable technology, wearables for short, and fashion, design and science is a highly promising and topical subject. Offered here is a compact survey of the theory involved and an explanation of the role technology plays in a fabric or article of clothing. The practical application is explained in detail and numerous illustrations serve as clarification. Over 50 well-known designers, research institutes, companies and artists, among them Philips, Burton, MIT Media Lab, XS Labs, New York University, Hussein Chalayan, Cute Circuit or International Fashion Machines are introduced by means of their latest, often still unpublished, project, and a survey of their work to date. Given for the first time is a list of all the relevant information on research institutes, materials, publications etc. A must for all those wishing to know everything about fashionable technology.

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Fadfada

Sharing personal problems and true feeling on social media has a lot of fears and is not likable nowadays, because of bullying, shaming, and making fun of the user by other users, Fadfada is a multi-platform social networking service, that aims to give the users the ability to share their problems or feeling via written newsfeed (posts) or videos (stories) that had an impact on their psychological health without revealing their true identity, by putting a mask on their faces and changing their voices after recording the story. In addition to extracting features from posts and stories to match users based on it.

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ESD Protection Device and Circuit Design for Advanced CMOS Technologies

ESD Protection Device and Circuit Design for Advanced CMOS Technologies is intended for practicing engineers working in the areas of circuit design, VLSI reliability and testing domains.

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Electronic engineering for neuromedicine

Advances in electronics have revolutionized diagnostic tools and created mobile medicine, touch-sensitive prosthetics, remote surgery, and artificial organs such as hearts, retinas, and bionic skins. This reference text shows the number of ways in which electronic engineering feeds into neuromedicine namely: the modelling and simulation of the brain, providing access to the brain, analysis of the signals and activities of the brain and influencing the function of the brain for therapeutic purposes. The areas of electronic engineering considered are electronic circuits, spectral analysis, filtering of signals, electromagnetic fields and wave propagation. The book is a valuable source to medical students and practitioners as well as electronic engineering and physics students and graduates.

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Diabetes mellitus and bacterial and fungal urinary tract infection

Diabetes mellitus is a heterogeneous group of disorders characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. Patients with type 2 diabetes mellitus are at increased risk of infections, with the urinary tract being the most frequent infection site. Various impairments in the immune system, in addition to poor metabolic control of diabetes, and incomplete bladder emptying due to autonomic neuropathy, may all contribute in the pathogenesis of urinary tract infections (UTI) in diabetic patients. Factors that were found to enhance the risk for UTI in diabetics include age, metabolic control, and long-term complications, primarily diabetic nephropathy and cystopathy. The spectrum of UTI in these patients ranges from asymptomatic bacteriuria (ASB) to lower UTI (cystitis), pyelonephritis, and severe urosepsis.

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Dermatotoxicology & respiratory toxicology = التسمم الجلدي والتنفسي

مصطلح " السم " غالبا يستخدم بالعامية لوصف المادة السامة - سواء كانت مادة آكالة (مخرشة)، أو مسرطنة، أو مطفرة، أو ماسخة، وإشارة إلى التلوث الضار وللتأكيد على مخاطر المواد الكيميائية. ويمكن تلخيص أساسيات علم السموم فيما يأتي: الجرعة /الاستجابة/ التعرض والاختلافات بالآثار الناتجة عن التعرض للخطر لدى الأشخاص. العديد منا يملك حس جيد بأساسيات السموم من خلال تجاربنا مع الكافيين و الكحول أو أي دواء أخر. وقد وجد أن آليات إصابة الجلد والرئتين تشكل سمية حادة أو مزمنة، حيث أن الاستعمال والجرعات المفرطة للمبيدات الحشرية أو الأدوية أو مواد أخرى تستهلك يوميا، يؤدي إلى تحويل هذين الجهازين (الجلدي والتنفسي) إلى بوابات للسمووقد وجد أيضا أن هامش العلاج ضيق جدا واحتمالية الدخول في النافذة السمية سهل جداز سنستعرض هنا أهم الآفات السمية الجلدية والرئوية من حيث آلية حدوثها وطرق علاجها.

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David Paul von Hansemann : Contributions to Oncology : Context, Comments and Translations

Presents translations of all the relevant German texts, and analyses the background and context of Hansemann's theories as well as the reasons why he was almost completely forgotten. It shows that some of Hansemann’s ideas may still be relevant to cancer research today, and that he deserves to be remembered in relation to cancer as Vordenker unter den führenden Denkern seiner Zeit - The foremost of the leading thinkers of his time.

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Load balancing using SDN

Software-Defined Network (SDN) is considered a breakthrough to the global network. It plays an important role in performance improvement and network optimization. SDN is a new mechanism for managing and designing networks rather than the current traditional network system which does not afford more services and higher data rates; therefore, we analyze the effect of applying load balancing techniques and its importance in different SDN environments. In this paper, we propose a dynamic server load balancing technique in SDN architecture. Hence, we implement a server Connection-based load balancing technique and evaluate its performance with a static Round-robin and Random-based in both mininet emulation environment and OpenFlow-enabled switch using Ryu OpenFlow controller.

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Les thérapies ciblées = Targeted therapies

We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.

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Le dépistage du cancer du sein : un enjeu de santé publique = Breast cancer screening: a public health issue

Fifteen years after the first experiments, the breast cancer screening program was rolled out in France in 2004. It is aimed at more than eight million women aged 50 to 74. Public health action on such a scale is exemplary in Europe and especially in France where the health system is not centralized. The new edition of this book takes stock of the current state of the program and its initial results. It updates technical and radiological aspects, assessment indicators, communication and forensic problems and finally the progress of foreign programs. The history of the French program is detailed from the 1990s until 2006, with the publication of the latest version of the specifications by the Directorate General of Health. The short and medium term objectives are re-specified: to increase the participation of women, to retain them and to further improve the quality of practices. The challenge is to combine the performance of screening and therapeutic management to finally achieve a clear reduction in mortality, which has remained stable for twenty years.

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Le cancer du sein = Breast cancer

The reader will find there both a synthetic summary of the current state of knowledge of epidemiology, risk factors and pathological aspects as well as a presentation of the surgical aspects, in particular, of the new approach that constitutes the sentinel node procedure. Radiotherapy, in a practical view, is divided into essential clinical questions. The medical treatment is then discussed according to the different situations encountered on a daily basis. Particular attention is of course paid to recent data both with the contribution of hormone therapy and targeted therapies. Finally, the symptomatic treatments and especially the psychological care of these patients are not forgotten.

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Karl Schuhmann, Selected papers on phenomenology

Selected papers on phenomenology offers the best work in this field by the acclaimed historian of philosophy, Karl Schuhmann (1941-2003),Topics covered include the development of Husserl's concept of intentionality, Husserl and Indian philosophy, the origins of speech act theory in Munich phenomenology, the historical background of the notion of "phenomenology", and Johannes Daubert's critique of Martin Heidegger,This book brings together, in chronological arrangement, fourteen papers. Though thirteen of these were published before in some form, several were not easily accessible so far. In addition, a substantial piece of research, Schuhmann's chronicle of Johannes Daubert.

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