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On the move to meaningful internet systemss 2005 : CoopIS, DOA, and ODBASE ; Vol. 3760 : OTM Confederated International Conferences, CoopIS, DOA, and ODBASE 2005, Agia Napa, Cyprus, October 31 - November 4, 2005, Proceedings Part I
such as the modeling of (legal) regulatory systems and the ubiquitous nature of their usage. Weweregladto seethatin 2005undertheinspiredleadershipofDr. Pilar Herrero, several of earlier successful workshops re-emerged with a second or even third edition (notably WOSE, MIOS-INTEROP and GADA), and that 5 new workshops could be hosted and successfully organized by their respective proposers: AWeSOMe, SWWS, CAMS, ORM and SeBGIS. .
On Communication : An interdisciplinary and mathematical approach
This book offers a radical new approach for the understanding of communication. By using the theoretical framework of complex systems theory communication is defined as the interplay of social and cognitive dynamics: communicators are modelled as complex cognitive systems who interact according to social rules and generate communicative systems. Messages generate meaning, which is understood as an attractor in the cognitive system of the receiver. Information is measured via the difference between a factual message and the message expected by the receiver.
Ocular Transporters in Ophthalmic Diseases and Drug Delivery
This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In Ocular Transporters in Ophthalmic Diseases and Drug Delivery, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium, and the transport of nutrients across the retinal pigment epithelium. It also provides an in-depth look at how mutations or dysfunction of specific transporters can contribute to various disorders in the eye, including blindness, and provides readers with potential targets and strategies to allow safe passage of therapeutic drugs into the eye.
Novel food grade enzymes : Applications in food processing and preservation industries
Covers all the aspects of food-grade enzymes, including their classification, kinetics, microbial production, biosynthetic pathways, commodity-wise industrial applications, and downstream processing strategies. The broad focus of this book is on the application of various classes of enzymes in dairy, fruits and vegetables, cereals and oilseeds, meat and poultry, and brewing and food packaging industries. Certain recent areas such as nanotechnological perspective in enzyme immobilization, infusion strategies as well as its efficient usage in food packaging and preservation are some of the salient highlights of this book. This book also discusses the aspects related to application of enzymes in functional food development and shelf life extension of various commodities food products.
Novel Developments for Sustainable Hydropower
This book presents (selected) new and innovative developments for sustainable and fish-friendly hydropower. It offers unique insights into the challenges, practices and policies of hydropower developments across 8 European countries, providing examples from on-site studies and European-wide analyses. The case studies throughout the book are practical “real-world” examples, which are intended to serve as inspiration for anyone who would like to know more about how solutions for more sustainable hydropower production can be designed and implemented. Hydropower is an important renewable energy source, which, however, can also impact aquatic ecosystems, fish populations and hydro-morphology. EU and national water, environmental and energy legislation strive for sustainable energy and water resource management as well as the protection of important habitats and species. These have an effect on the requirements and decision making processes for hydropower planning, commissioning and operation. With a high variety of measures existing and site-specific conditions as well as national and EU level legal requirements to consider, it can be difficult to determine, what issues to address and which measures to implement.
Nonlinear Structural Engineering : With Unique Theories and Methods to Solve Effectively Complex Nonlinear Problems
This book is aiming to concentrate on the nonlinear static and dynamic analysis of structures and structural components that are widely used in everyday engineering applications. It approaches a nonlinear problem by mathematically converting it into an exact equivalent pseudolinear one, in contrast to commonly used approaches which are based on linear concepts. The new concepts, theories and methods introduced in this book, simplify a great deal the solution of the complex nonlinear problems, and also allow for the correct usage of the powerful existing linear methods of analysis.
New horizons for a data-driven economy : A roadmap for usage and exploitation of big data in Europe
The book is structured in four parts: Part I “The Big Data Opportunity” explores the value potential of big data with a particular focus on the European context. It also describes the legal, business and social dimensions that need to be addressed, and briefly introduces the European Commission’s BIG project. Part II “The Big Data Value Chain” details the complete big data lifecycle from a technical point of view, ranging from data acquisition, analysis, curation and storage, to data usage and exploitation. Next, Part III “Usage and Exploitation of Big Data” illustrates the value creation possibilities of big data applications in various sectors, including industry, healthcare, finance, energy, media and public services. Finally, Part IV “A Roadmap for Big Data Research” identifies and prioritizes the cross-sectorial requirements for big data research, and outlines the most urgent and challenging technological, economic, political and societal issues for big data in Europe.
New developments in nanosensors for pharmaceutical analysis ; 1st ed.
Presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors.
New Business Models for the Reuse of Secondary Resources from WEEEs : The FENIX Project
This book summarizes research being pursued within the FENIX project, funded by the EU community under the H2020 programme, the goal of which is to design a new product service paradigm able to promote innovative business models, to open added value to the vessels and to create new market segments. It experiments and validates its approach on three new concepts of added-value specialized vessels able to run requested services for several maritime sectors in the most effective, efficient, economic valuable and eco-friendly way. The three vessels share the same lean design methodology, IoT tools and HPC simulation strategy: a lean fact-based design model approach, which combines real operative data at sea with lean methodology, to support the development and implementation of the vessel concepts; IT customized tools to enable the acquisition, processing and usage of on board and local weather data, through an IoT platform, to provide business services to different stakeholders; HPC simulation, providing a virtual towing tank environment, for early vessel design improvement and testing. The book demonstrates that an integrated LCC analysis and LCC strategy to guarantee sustainability to vessels concepts and the proper environmental attention inside the maritime industry.
Neural networks and deep learning
Covers both classical and modern models in deep learning. The primary focus is on the theory and algorithms of deep learning. The theory and algorithms of neural networks are particularly important for understanding important concepts, so that one can understand the important design concepts of neural architectures in different applications. Why do neural networks work? When do they work better than off-the-shelf machine-learning models? When is depth useful? Why is training neural networks so hard? What are the pitfalls? The book is also rich in discussing different applications in order to give the practitioner a flavor of how neural architectures are designed for different types of problems.
Neural Nets ; 16th Italian Workshop on Neural Nets, WIRN 2005, International workshop on natural and artificial immune systems, NAIS 2005, Vietri sul Mare, Italy, June 8-11, 2005, Revised Selected Papers
This book constitutes the thoroughly refereed postproceedings of the 16th Italian Workshop on Neural Nets, WIRN 2005, as well as the satellite International Workshop on Natural and Artificial Immune Systems, NAIS 2005, held in Vietri sul Mare, Italy in June 2005. The 41 revised papers presented together with a lecture by the winner of the Premio Caianiello award were carefully reviewed and improved during two rounds of selection and refereeing.
Natural Products Targeting Clinically Relevant Enzymes
Covers the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
Multiscale Optimization Methods and Applications
One general strategy for dealing with a large or difficult problem is to partition it into smaller ones, which are hopefully much easier to solve, and then work backwards towards the solution of original problem, using a solution from a previous level as a starting guess at the next level.The topics of the chapters selected for this volume are focused on the development of new solution methodologies, including general multilevel solution techniques, for tackling difficult, large-scale optimization problems that arise in science and industry. Applications presented in the book include but are not limited to the circuit placement problem in VLSI design, a wireless sensor location problem, optimal dosages in the treatment of cancer by radiation therapy, and facility location.
Multi-Scale Approaches in Drug Discovery : From Empirical Knowledge to In silico Experiments and Back
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
MSCs and Innovative Biomaterials in Dentistry
Presents the modern concepts of mesenchymal stem cells (MSCs) and biomaterials as they pertain to the dental field. The book is organized around three main topics: MSCs biology, advanced biomaterials, and clinical applications. The chapters present basic information on stem cell biology and physiology, modern biomaterials that improve bone tissue regeneration, the biomatrices like platelet-rich fibrin (PRF) used to functionalize the biomaterials surface, the strategic and safe intraoral seats of harvesting, the new sources for MSCs, as well as the future perspectives and new challenges in these exciting fields.
Mosby's 2024 nursing drug reference
Makes it easy to find the most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled — including more than 25 new entries for drugs recently approved by the FDA. And no other drug guide places a higher emphasis on patient safety, with Black Box Warnings for dangerous adverse reactions, High Alerts for drugs with the greatest risk, and a focus on both common and life-threatening side effects. From nursing pharmacology expert Linda Skidmore-Roth, this perennial bestseller proves there is a difference in drug guides.
Mosby’s dental drug reference
Profiles the most commonly used drugs in dentistry, with emphasis on dental-specific considerations. More than 800 drug monographs make it easy to find information such as dosages, indications, contraindications, interactions, precautions, side effects, and serious reactions.
Modern pharmaceutics
Covers the curriculum and syllabus developed by the Pharmacy Council of India, providing students with the necessary knowledge and skills required in the field of pharmaceutical services
Modern deep learning for tabular data : Novel approaches to common modeling problems
Synthesizes and presents novel deep learning approaches to a seemingly unlikely domain - tabular data. Whether for finance, business, security, medicine, or countless other domain, deep learning can help mine and model complex patterns in tabular data - an incredibly ubiquitous form of structured data. Part I of the book offers a rigorous overview of machine learning principles, algorithms, and implementation skills relevant to holistically modeling and manipulating tabular data. Part II studies five dominant deep learning model designs - Artificial Neural Networks, Convolutional Neural Networks, Recurrent Neural Networks, Attention and Transformers, and Tree-Rooted Networks - through both their 'default' usage and their application to tabular data. Part III compounds the power of the previously covered methods by surveying strategies and techniques to supercharge deep learning systems: autoencoders, deep data generation, meta-optimization, multi-model arrangement, and neural network interpretability.
Modern aspects of pharmaceutical quality assurance : developing and proposing application models, SOPs, practical audit systems for pharma industry
Aims to develop a tool that will substantially decrease the number of Inspectional Observations and Warning letters, thus eliminating Import Alerts and Consent Decree. This book targets the Pharmaceutical Industry and students of Pharmaceutical Quality Assurance so they can get in hand-ready consolidated information on Pharmaceutical Quality guidelines, Quality metrics, and implementation of simplified SOP guidelines, plant layouts to implement Quality metrics for Pharmaceutical Manufacturing systems in tablets, capsules, liquid orals, and semi-solid dosage forms.
