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Open and Closed Innovation : Different Cultures for Different Strategies
Open Innovation is a phenomenon in both research and management practice. Since radical innovation or new business development often require external technologies or ways of commercialization, many firms have shifted from a Closed to an Open Innovation model. However, firms often face difficulties during the implementation. While the implementation effort usually focuses on external ideas and technologies as well as the processes to identify them, cultural challenges are neglected. Philipp Herzog develops a theoretical framework arguing that Open Innovation and Closed Innovation cultures need to be different (e.g. regarding the not-invented-here (NIH) syndrome). Based on a multi-respondent survey among 120 R&D employees from three business units of a leading chemical firm, he provides empirical evidence for many of the hypothesized differences in innovation culture.
Ontology Matching
Euzenat and Shvaiko’s book is devoted to ontology matching as a solution to the semantic heterogeneity problem faced by computer systems. Ontology matching aims at finding correspondences between semantically related entities of different ontologies. These correspondences may stand for equivalence as well as other relations, such as consequence, subsumption, or disjointness, between ontology entities.
Nutrition and Gastrointestinal Disease
Nutritional support of people with gastrointestinal impairment is critical to treatment and ultimately successful management. As such, gastroenterologists should be experts in nutrition and knowledgeable about the affects of nutrition on disease management. Nutritional and Gastrointestinal Disease fulfills that need, serving as a hands-on, practical reference in nutrition support for the clinical gastroenterologist and other clinicians with similar interests. The volume offers expert nutritional knowledge and management ideas as well as methodology for combating problems such as short bowel syndrome, inflammatory bowel disease, celiac disease and obesity. Renowned authorities also investigate nutrition’s influence on such issues as liver failure and acute pancreatitis. While gastroenterology training programs around the world remain deficient in their nutrition curriculum, Nutritional and Gastrointestinal Disease provides a comprehensive and groundbreaking support for clinical gastroenterologists.
Nutraceuticals in obesity management and control
Provides detailed information on nutraceuticals that can be helpful in the control and management of obesity. It clarifies key aspects of nutraceuticals that include sources, extraction, chemistry, mechanisms of action, pharmacology, bioavailability, safety, and various applications. Beginning with a concise overview of the prevalence of obesity, complications related to obesity, and current treatment regimens, the volume delves into the roles of functional foods and nutraceuticals for the management of body weight and for alleviating obesity comorbidities. It goes on to discuss the effect of some of the most commonly and frequently used naturally occurring nutraceutical substances, along with their mechanisms of action in controlling obesity. The volume looks at the role of nutraceutical fruits as well as the beneficial aspects of carotenoids in fruits and vegetables and explores antioxidant-rich nutraceuticals, the role of vitamins and supplements, the use of green tea, and the potential of pseudocereals and spices in the management of metabolic syndrome.
Nutraceuticals and bone health
Here is an informative volume on the importance of nutraceuticals and herbal remedies for bone health. It explains the probable mechanisms of nutraceuticals for the prevention, treatment, and management of bone-related diseases as well as their curable effects on bone injuries. The volume covers the progression and development of bones, which is a multifaceted process that requires an endless and ample supply of nutrients, such as calcium, phosphorus, potassium, protein, vitamin D, magnesium, and fluoride. The book delves into the beneficial effects of nutraceuticals on overall bone health and for the treatment of bone disorders such as osteoporosis, bone fractures, scoliosis and related complications, rheumatoid arthritis, Paget’s disease, bursitis, gout, and carpal tunnel syndrome. It also addresses the use of nutraceuticals for inflammatory deformities and rickets.
Nutraceutical fruits : Overview and disease prevention
While nutritional supplements have enormous advantages, food ingredients such as fruits and vegetables can play a significant preventative and therapeutic role in our daily lives. Fruits are found to have anti-inflammatory, antibacterial, antifungal, and chemopreventive properties that can boost health, as well as prevent diseases. This new book explores the use of fruits as nutraceuticals for alternative treatment, as well as for disease prevention. It looks at how nutraceutical fruits can be used to prevent and manage a range of diseases that include mental illness, cancer, respiratory and lung diseases, cardiovascular diseases, liver disease, inflammatory bowel diseases, sleep disorders, etc. The book also looks at the roles of nutraceutical fruits in the metabolic syndrome and provides information regarding the safety and toxicity of neutraceutical fruits.
Novel Plant Imaging and Analysis : Water, Elements and Gas, Utilizing Radiation and Radioisotopes
This book is only an introduction to show that radiation and radioisotopes (RI) are premier tools to study living plant physiology which leads to new findings. Who had ever imagined that we could see water in a plant? Who had ever imagined that we could see ions moving toward roots in solution? Who had ever imagined that we could see invisible gas (CO2) fixation and movement in a plant? These studies demonstrated for the first time that water, ions and gas can be visualized in living plants, which could be hardly seen by anyone before. This publication summarizes the results obtained by Nakanishi’s lab in The Univ. of Tokyo, based on her original concept and her original tools or systems. It is useful for professional scientists, plant physiologist, and those studying plant imaging.
Non-Vitamin K Antagonist Oral Anticoagulants : A Concise Guide
An essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides a unique and valuable resource in the cardiovascular field, both for those currently in training, and for those already in clinical or research practice.
Non-Linear Electromechanics
This is the first book in which problems of electromechanics are considered from the perspective of analytical mechanics. The book includes fundamental results in the theory of non-linear electromechanical systems and will be useful both for researchers, engineers, scholars and graduate students of electromechanical faculties of technical universities. It includes not only theoretical results but also various examples from many industrial applications. A sizeable part of the book is devoted to the general theory of synchronous machines and electro-magnetic exciters of oscillations.
Nonlinear and Adaptive Control with Applications
Nonlinear and Adaptive Control with Applications provides a detailed treatment of the design of robust adaptive controllers for nonlinear systems with uncertainties. The authors employ a new tool based on the ideas of system immersion and manifold invariance.
New Vision of Metformin in treating cancer
The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.
New Trends in Databases and Information Systems ; ADBIS 2020 Short Papers, Lyon, France, August 25–27, 2020, Proceedings
This book constitutes thoroughly refereed short papers of the 24th European Conference on Advances in Databases and Information Systems, ADBIS 2020, held in August 2020. ADBIS 2020 was to be held in Lyon, France, however due to COVID-19 pandemic the conference was held in online format. The 18 presented short research papers were carefully reviewed and selected from 69 submissions. The papers are organized in the following sections: data access and database performance; machine learning; data processing; semantic web; data analytics.
New approach to deal with fibromyalgia
You must have walked once among the colorful fields of flowers, enjoying their colors, aromas and touches, but have you ever thought that these beautiful creatures could contain many constituents that have healing properties and be one day a part of your therapy ! Aromatherapy is a holistic healing treatment that uses natural plant extracts to promote health and well-being; it is used in the management of many diseases including a very common syndrome nowadays: Acute or chronic stress/ pain in localized body spots may trigger or aggravate symptoms knowon as fibromyalgia (FM). In this research we're going to discuss this syndrome which is very widespread, but rarely well-diagnosed and associated with many complex and unclear mechanisms. A new approach to deal with FM will be introduced to you subsequently.
Neurocutaneous Disorders : Phakomatoses and Hamartoneoplastic Syndromes
Neurocutaneous diseases are a wide group of conditions that affect the nervous system but appear as lesions of the skin. Some of the more common entities have variable forms of expression that can confuse the diagnosis; for the rare conditions it is difficult to find descriptions in the literature. Recent insights into their cellular, biochemical and molecular genetic bases have shown the essential need for a new nosology and updated genotype-phenotype correlations. The book provides an authoritative source of knowledge about these difficult problems and bridges the gap between clinical recognition and the new molecular medicine. The editors, distinguished clinicians and geneticists, assembled an internationally renowned group of collaborators, many of them the experts who first described a particular disorder or established its present accepted definition.
Neurocutaneous disorders : A clinical, ciagnostic and therapeutic approach
Provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders.
Neuroacanthocytosis Syndromes II
Awareness of neuroacanthocytosis disorders has increased significantly in recent years. There have been a number of important developments in the field since the publication of the first volume, Neuroacanthocytosis Syndromes. This book contains the latest research in this area. Recent advances have identified the range of mutations in the causative genes, shedding light on potential phenotypegenotype correlations. Studies of the proteins affected in these disorders have resulted in increased understanding of their functions and distribution. In vitro studies have identified potential protein interactions, which have important implications for pathophysiology. Work on erythrocyte membranes suggests mechanisms for the generation of acanthocytes. Animal models are being generated which will greatly facilitate understanding the role of gene mutations in humans, and provide the foundation for possible therapeutic interventions. In addition, advances in other neurodegenerative disorders, such as Huntington’s and Parkinson’s diseases, have implications for neuroacanthocytosis.
Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
Nanomechanics of Materials and Structures
This book is derived from the proceedings of the International Workshop on Nanomechanics held at Asilomar Conference Grounds in Pacific Grove, California on July 14-17, 2004. The main objective was to convene leading researchers in the nanotechnology community to assess the current state-of-the-art and disseminate recent progress, critical issues, barriers to applications, and directions for future research in nanomechanics.
Myelodysplastic Syndromes
This book summarizes our current knowledge of MDS, from very basic aspects to the clinical management. It provides guidance to the diagnosis, an understanding of disease mechanisms, and a discussion of treatment strategies.
Multiwavelength Approach to Unidentified Gamma-Ray Sources : A 2nd Workshop on the Nature of the High-Energy Unidentified Sources
Nearly one half of the point-like gamma-ray sources detected by EGRET instrument of the late Compton satellite are still defeating our attempts at identifying them. To establish the origin and nature of these enigmatic sources has become a major problem of current high-energy astrophysics. The second workshop on Multiwavelength Approach to Unidentified Gamma-ray Sources intends to shed new and fresh light on the problem of the nature of these mysterious sources and the objects behind them. The proceedings contain 46 contributed papers in this subject, which cover theoretical models on gamma-ray sources as well as the best multiwavelength strategies for the identification of the promising candidates. The topics of this conference also include energetic phenomena ocurring both in galactic and extragalactic scenarios, phenomena that might lead to the appearance of what we have called high-energy unidentified sources. The book will be of interest for all active researchers in the high-energy astrophysics and related research areas as well as for scientists and graduate students interested in understanding the recent progress in this field.
