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Zebrafish : Methods and protocols
Introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Web Intelligence Meets Brain Informatics ; 1st WICI International Workshop, WImBI 2006, Beijing, China, December 15-16, 2006, Revised Selected and Invited Papers
the book include: workshop was the first in the field to focus on the interplay between (a) intelligent technologies, especially in the context of WI and (b) studies on human intelligence as explored in neuroscience, cognitive psychology, and brain science instrumentation.The book, as a volume in the Springer LNCS/LNAI state-of-the-art survey, will be a milestone publication, with research visions and blueprints, for com-puter scientists and practitioners at large in this exciting interdisciplinaryarea.
Visual Development
Research on visual development now spans a wide variety of disciplines encompassing biochemistry, anatomy, electrophysiology, psychophysics, clinical ophthalmology, and other related topics. It is difficult to present a thorough overview of such a broad range of topics in a simple, concise manner. However, Nigel Daw has masterfully accomplished this task in his book. It is well organized, informative, easy to read, and enjoyable.
Ultradian Rhythms from Molecules to Mind : A New Vision of Life
Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.
Tutorials in Mathematical Biosciences I : Mathematical Neuroscience
Introduces some basic theories on computational neuroscience. Chapter 1 is a brief introduction to neurons, tailored to the subsequent chapters. Chapter 2 is a self-contained introduction to dynamical systems and bifurcation theory, oriented towards neuronal dynamics. The theory is illustrated with a model of Parkinson's disease. Chapter 3 reviews the theory of coupled neural oscillators observed throughout the nervous systems at all levels; it describes how oscillations arise, what pattern they take, and how they depend on excitory or inhibitory synaptic connections. Chapter 4 specializes to one particular neuronal system, namely, the auditory system. It includes a self-contained introduction, from the anatomy and physiology of the inner ear to the neuronal network that connects the hair cells to the cortex, and describes various models of subsystems.
Transgenic and Knockout Models of Neuropsychiatric Disorders
Neuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond.
Transcriptional Regulation by Neuronal Activity : To the Nucleus and Back
Regulation of gene transcription by neuronal activity is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury. In the field of activity-dependent gene expression, rapid progress is being made that can impact these, and many other areas of neuroscience. The major aim of Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back is to illustrate key advances in the field – specifically how signals are transmitted to the nucleus in response to neuronal activity, what genes are activated and how this is achieved, and how these changes in gene expression alter neuronal function.
The Statistical Analysis of Functional MRI Data
One of the most intriguing questions facing modern science is the inner workings of the human brain. Functional magnetic resonance imaging (fMRI) is a powerful tool used to study the human brain in action. The data produced from mapping the active processes within the brain present many challenges to statisticians, computer scientists, engineers and other data analysts, due to their complex structure and the ever-increasing sophistication of the scientific questions being posed by researchers. This book represents the first in-depth discussion of statistical methodology, which it couples with an introduction to the scientific background needed to understand the data.
The Rosetta Stone of the Human Mind : Three languages to integrate neurobiology and psychology
The Rosetta Stone to the Human Mind: Three Languages to Integrate Neurobiology and Psychology illustrates how the simultaneous use of these two approaches enriches the understanding of the neural and mental realms, and adds new dimensions to our perception of neuropsychological events.
The Proteasome in Neurodegeneration
This book contains up-to-date reviews on different aspects of the ubiquitin proteasome system and its involvement in several neurodegenerative diseases. It is an indispensable source of information for scientists studying neurodegeneration. The book provides information on the basics of the ubiquitin proteasome system, but mainly describes a number of aspects of involvement of this system in neurodegeneration. All major hypotheses on the possible causes of neurodegeneration, such as oxidative stress, inflammation, and aging, are discussed in view of their effect on the ubiquitin proteasome system.
The Pain Management Workbook : Powerful CBT and Mindfulness Skills to Take Control of Pain and Reclaim Your Life
You'll find a comprehensive outline of this effective biopsychosocial approach, as well as scientifically supported interventions rooted in cognitive- behavioral therapy (CBT), mindfulness, and neuroscience to help you take control of your pain--and your life! You'll learn strategies for creating a pain plan for home and work, reducing reliance on medications, and breaking the pain cycle. Also included are tips for improving sleep, nutrition for pain, methods for resuming valued activities, and more.
The Oxford handbook of neuronal ion channels
Neurons are excitable cells. They use ions and electrical signaling to talk to each to other, and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons. The book explains how ion channels open and close, how they can be selective for specific ions, and how they give rise to action potentials. There are in-depth chapters discussing specific classes of ion channels: potassium channels, sodium channels, neurotransmitter-gated ion channels, and other specialized channels. Throughout the handbook, important insight is provided on the contribution ion channels make to neuronal excitability and to synaptic transmission. The handbook goes further to discuss a group of human diseases such as epilepsy, pain, and migraines that can be caused by ion channel dysfunction called channelopathies. For neuroscientists, biophysicists, and neuropharmacologists, this handbook is a valuable reference of ion channel biology and function.
The Origins of Language : Unraveling Evolutionary Forces
Developments in cognitive science indicate that human and nonhuman primates share a range of behavioral and physiological characteristics that speak to the issue of language origins. This volume has three major themes, woven throughout the chapters. First, it is argued that scientists in animal behavior and anthropology need to move beyond theoretical debate to a more empirically focused and comparative approach to language. Second, those empirical and comparative methods are described, revealing underpinnings of language, some of which are shared by humans and other primates and others of which are unique to humans. New insights are discussed, and several hypotheses emerge concerning the evolutionary forces that led to the "design" of language. Third, evolutionary challenges that led to adaptive changes in communication over time are considered with an eye toward understanding various constraints that channeled the process.
The Nonlinear Universe : Chaos, Emergence, Life
The book explains the wide-ranging implications of nonlinear phenomena for future developments in many areas of modern science, including mathematics, physics, engineering, chemistry, biology, and neuroscience.
The NeuroProcessor : An integrated interface to biological neural networks
This book presents the Neuroprocessor, a novel computational neuronal interface device implemented in VLSI technology. In addition to neuronal signals acquisition, it can process the data, generate stimuli and transmit the data over wireless channels, while using minimum electric energy.
The Making of a Neuromorphic Visual System
The book reviews theories of visual object and shape recognition in the fields of computer vision, neuroscience and psychology. The entire range of computations is discussed, as for example contour extraction in retinal circuits, orientation determination in cortical networks, position and scale independence of shape, as well as the issue of object and shape representation in a neural substrate.
The Influence of Genetics on Contemporary Thinking
Reflects on the effects of recent discoveries in genetics on a broad range of scientific fields. In addition to neuroscience, evolutionary biology, anthropology and medicine, contributors analyze the effects of genetics on theories of health, law, epistemology and philosophy of biology.
The Inferior Colliculus
Winer and Schreiner's The Inferior Colliculus is the first critical, comprehensive reference presenting the current knowledge of the inferior colliculus from a variety of perspectives, including anatomical, physiological, developmental, neurochemical, biophysical, neuroethological and clinical vantage points. the book is an ideal introduction to the inferior colliculus and central auditory processing for clinicians, otolaryngologists, graduate and postgraduate research workers in the auditory and other sensory-motor systems.
The Human Nervous System : Structure and Function
Offers medical students and interested neuroscientists a readily understandable and awe-inspiring view of the organization of the human nervous system. Its explanatory power and visual insight make this book an indispensable source of quick understanding that readers will consult gratefully again and again.
The human hippocampus : Functional anatomy, vascularization and serial sections with MRI
This book offers a precise description of the anatomy of human hippocampus in view of neurosurgical progress and the wealth of medical imaging methods available. A survey of the current concepts explains the functions of the hippocampus and describes its external and internal vascularisation. Head sections and magnetic resonance images complete this comprehensive view of human hippocampal anatomy. It will be of interest to neuroscientists and, in particular, to neurosurgeons, neuroradiologists and neurologists.
