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Zinc Finger Proteins: From Atomic Contact to Cellular Function
The scientists discovered a novel domain associated with zinc, and named this domain "zinc finger. " The number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc finger proteins fi-om variou s viewpoints. This field is a good example of how a new science begins with the insight of a few scientists and how it develops by efforts of numerous independent scientists, in contrast to a policy-driven scientific project, such as the Human Genome Project, with goals clearly set at its inception and with work performed by a huge collaboration throughout the world. As more zinc finger proteins were discovered, several subfamilies, such as C2C2, CCHC, CCCH, LIM, RING, TAZ, and FYVE emerged, increasing our understanding of zinc fingers. The knowledge was overwhelming. Moreover, scientists began defining the term "zinc finger" differently and using various names for identical zinc fingers.
Visualization : Theory and Practice in Science Education
External representations (pictures, diagrams, graphs, concrete models) have always been valuable tools for the science teacher. The formation of personal, internal, representations – visualizations – from them plays a key role in all learning, especially in that of science. The use of personal computers and sophisticated software has expanded into the areas of simulation, virtual reality, and animation, and students now engage in the creation of models, a key aspect of scientific methodology. Several academic disciplines underlie these developments, yet act independently of each other, to the detriment of an attainment of what is possible. This book brings together the insights of practicing scientists, science education researchers, computer specialists, and cognitive scientists, to produce a coherent overview. It links presentations about the cognitive theory of representation and visualization, its implications for science curriculum design, and for learning and teaching in classrooms and laboratories.
Upon What Does the Turtle Stand? : Rethinking Education for the Digital Age
Brings together the reflections of independent researchers from around the world. Sixteen authors from fourteen countries present their views on the use of information and communication technology (ICT) in education, offering valuable insights through the examination of current issues relevant to the future of education. What will education be in tomorrow’s world? How can ICT be used without rendering education a purely technical process? How can we succeed the renovation of educational subjects without transforming them into technical objects? The introductory chapter of this publication guides us into the essays through a classification organized by the editors to illustrate different attitudes to technologies: The ‘Globalizers’ see the integration of ICT and education as a means of enhancing the competitiveness of their society in a global economy / The ‘Reformists’ see it as a means of bringing about significant change in didactics in the various disciplines, and even in the ‘basics’ of education / The ‘Humanists’ consider technologies as possible catalysts for changing the aims and values of education from learni- oriented to humanistic
Two Minds : Intuition and Analysis in the History of Economic Thought
Intuition is warm and fuzzy, qualitative, not measurable. Economics, on the other hand, is quantitative, and if it is not a hard science, at least it is the "queen of the social sciences." It is, therefore, intuitively obvious, that intuition and economics are as if oil and water. The problem is, what is intuitively obvious is not always correct. And, there are two major reasons why intuition and economics are not like oil and water. First, economics concerns itself with decision making, and decisions are made in the brain. The human brain is the size of a grapefruit, weighing three pounds with approximately 180 billion neurons, each physically independent but interacting with the other neurons. What we call intuition is, like decision making, a natural information processing function of the brain. Second, despite the current emphasis on quantitative analysis and deductive logic there is a rich history of economists speaking about intuition. First, the human brain, specifically the neocortex, has a left and right hemisphere. The specialized analytical style of the left hemisphere and the specialized intuitive style of the right hemispheres complement each other.
Trust Management ; Vol. 3477 ; 3rd International Conference, iTrust 2005, Paris, France, May 23-26, 2005, Proceedings
The purpose of the iTrust working group is to provide a forum for cro- disciplinary investigation of the applications of trust as a means of increasing security, building con?dence and facilitating collaboration in dynamic open s- tems. The notion of trust has been studied independently by di?erent academic disciplines, which has helped us to identify and understand di?erent aspects of trust. Theaimofthisconferencewastoprovideacommonforum,bringingtogether researchers from di?erent academic branches, such as the technology-oriented disciplines, law, social sciences and philosophy, in order to develop a deeper and more fundamental understanding of the issues and challenges in the area of trust management in dynamic open systems.
Topics in Elementary Geometry
This small book has for a long time been a unique place to find classical results from geometry, such as Pythagoras' theorem, the nine-point circle, Morley's triangle, Poncelet's polygons, and many other subjects. In addition, this book contains recent, geometric theorems which have been obtained in this classical field over the past years. There are 27 independent chapters on a wide range of topics in elementary plane Euclidean geometry, at a level just beyond what is usually taught in a good high school or college geometry course. The selection of topics is intelligent, varied, and stimulating. In a small space the author provides many thought-provoking ideas.
Theory of Chemical Reaction Dynamics
The book represents a snapshot of the current status of research in reaction dynamics, focusing especially on accurate time-dependent and time-independent methods of quantum scattering, treatment of non-adiabatic processes, studies of associative and inelastic collisions, calculation of potential surfaces.the experiments now offer detailed scattering information for theory to explain and rationalize. At the same time, advances in computing and networking technologies for heterogeneous and grid environments afford new possibilities for theoretical studies of chemical reactivity. As a consequence, calculation of atom+diatom reactions has become routine, accurate methods have been developed to describe reactions in tetra-atomic systems, nonadiabatic reactions are being studied in simultaneous experimental and theoretical efforts, and statistical theories of unimolecular reaction dynamics are applied to systems that were a mystery a few years ago.
Theoretical Atomic Physics
This established text and reference contains an advanced presentation of quantum mechanics adapted to the requirements of modern atomic physics. It includes topics of great current interest such as semiclassical theory, chaos and Bose-Einstein condensation in atomic gases. The third edition of Theoretical Atomic Physics extends the successful second edition with a detailed treatment of the wave motion of atoms near the anticlassical or extreme quantum regime, and it also contains an introduction to some aspects of atom optics that are relevant for current and future experiments involving ultra-cold atoms. Various problems are included together with complete solutions. Because it has more emphasis on theory, this book enables the reader to appreciate the fundamental assumptions underlying standard theoretical constructs and to embark on independent research projects.
The Values of Independent Hip-Hop in the Post-Golden Era : Hip-Hop’s Rebels
Illuminates a subculture that is rarely explored, shining a light on independent hip-hop’s power to counter mainstream ideology.it aims to understand the complex and contradictory cultural politics of independent hip-hop in the contemporary age.
The Theory of Coherent Radiation by Intense Electron Beams
This books delves into the foundations of a device and geometry independent theoretical treatment of a large collection of interacting and radiating electron bunches. Part I deals with the basics of the radiation emission of a single charged particle, paying particular attention to the effect of radiation reaction and dwelling on the corresponding well-known paradoxes. Part II investigates the collective behaviour of a high-density electron bunch where both discrete and continous beam modelling is explored. Part III treats the application to modern systems while still keeping the treatment as general as possible. This book will be mandatory reading for anyone working on the foundations of modern devices such as free electron lasers, plasma accelerators, synchroton sources and other modern sources of bright, coherent radiation with high spectral density.
The Impact of The Macroeconomic Variable on Saudi Arabia Stock Market from (2005 – 2019)
The study aim to examine the relationship between macroeconomic variables and the Saudi Arabia stock market over the period (2005 to 2019). The dependent variable used in this study are Ratios of public debt to GDP (D/GDP), Average per capita income (APCI), and Interest Rate, Gold volume and Oil Price, Gross domestic product and the independent variable is the market index “Tadawul All Share index (TASI)”. In the results we could not find a linear equation because P-value was bigger than ALFA in the NOVA test, and the reason is mentioned in the study.
The impact of leadership behavioral integrity and trust on the employees’ organizational trust : Empirical Evidence from the private health sector in Syria
Examines the effect of leader trust and leader behavioral integrity on the employee’s organization trust. Based on the assumption that there is a direct link between leader trust and leader behavioral integrity (Independent Variables), on organization trust (Dependent Variable), we have examined the relationship between these variables. The research methodology applies a deductive quantitative approach that collects quantifiable data by using survey instrument. Sampling strategy included interviewing employees across different hospitals which makes up 84.37% of the data, and from an online form that was shared on social media platforms making 15.62% of the data.
The impact of financial leverage and operational efficiency on the profitability of Syrian banks using Dupont model
Aims to reveal the influence of the financial leverage and operational efficiency on the profitability of Syrian banks and the extent of the possibility of using the debt to increase profitability. To achieve the objectives of the study, the necessary data were collected for the variables of the study which is independent variables represented by financial leverage (equity multiplayer) and operational efficiency (assets utilization, net profit margin). The dependent variable profitability is expressed as the return on assets.
The Impact of E-trading on the liquidity of Damascus Securities Exchange
This study aims to evaluate the impact of introducing electronic trading system in Damascus Securities Exchange (DSE) on market liquidity. To achieve this objective, we collect data on trading volume before and after the introduction of e-trading It is the only authorized entity in Syria in which previously issued securities are traded in the primary market for the whole period (2020-2022). Using SPSS, we apply the independent sample t-test to answer this question. We document an increase in trading volumes after the introduction of the e-trading services slightly but insignificantly. That is, after offering E-trading, we figured out an increase in the number of shares traded, however,it did not make a significant differences in trading volumes.
The effects of the earthquake natural disaster on corporate social responsibility in Syria
Shines a light on the impact of the recent earthquake that struck Syria on corporate social responsibility (CSR) of the business sector, NGOs, charities, and individuals. In this study, the earthquake was considered as the independent variable and CSR to be the dependent variable, with the addition of two moderating variables – the location and type of organisation – three hypotheses were tested. This study focused on the type of aid, logistics, challenges, and type of organization and locations of the organization...
The effect of training expenses on financial performance : A study on a sample of Syrian banks
Investigates the impact of human resources training expenses on financial performance in Syrian commercial banks. Training expenses were considered the independent variable, while financial performance represented by ROA (Return On Assets) and ROE (Return On Equity) was the dependent variable. The age of the bank was included as a control variable in the study. The target population consisted of all 11 Syrian banks listed on the Damascus Securities Exchange. The researchers relied on using panel data, which takes into account the effects of individual factors and time when estimating regression equations.
The Diabetic Kidney
In The Diabetic Kidney, a stellar group of international researchers and clinicians joins forces to independently survey recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. Drawing on many years of experience, the authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Not always in total agreement, their views reflect the present state of knowledge and its uncertainties, and offer a composite of different authoritative views on the causes of diabetic kidney disease.
The Coherence of Kants Transcendental Idealism
Presents a new defense of the coh- ence and plausibility of Kant’s transcendental idealism and its indisp- sability for his theory of knowledge. I will show that the main argument of the Transcendental Aesthetic and the Transcendental Analytic is - fensible independently of some of Kant’s claims which are said to threaten its coherence. I have undertaken an inquiry into the coherence of Kant’s transc- dental idealism for the following reasons. A defense of the coherence of transcendental idealism is required by the existing state of Kantian scholarship. The claim that Kant’s transcendental idealism is incoh- ent has appeared in various forms over the last two centuries.
The Bacteria : Their Origin, Structure, Function and Antibiosis
This book may seem like three or four books even though the main - cus is on a specialized topic—the bacterial cell wall. Its job is to formulate the innovations that caused life to initiate on earth, those that caused cell physiology to develop without diversity developing, those that allowed the murein walls of the cells to arise, those that led to the separation of the domain of Bacteria from other organisms, those that allowed the Archaea and the Eukarya to develop independently, and those that then led to the development of a very diverse b- sphere.
The Art and science of color in holistic interior design : A crash course
Color sets the mood, and choosing a harmonious color palette for your interior design project is key to establishing the overarching theme, mood, and ambience of your design vision. The color consultation is an opportunity to explore your design vision with an experienced professional in order to create a custom curated room color palette that authentically reflects your style and clearly communicates overarching design themes.Choosing and combining colors in interior design requires a background in color theory and at least a little glimpse into the science of why we see different colors the way we do. That's because this technical knowledge is what allows a designer to create meaningful and striking color combinations or even manipulate light and color to create near-illusions, such as making a space appear larger, making the ceiling appear higher or lower, or even tricking the eye into perceiving two different colors as the same.
