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New Vision of Multiblesclerosis
"There is an evidence that both the multiple sclerosis increased prevalence and incidence rate of over the last few decades. Therefore, the goal of our study is to highlight the causes and the risk factors of such neurological disease in order to raise the public awareness for its early symptoms to be able to treat the patients as early as possible and to have the best outcome. The symptoms of this disease are similar to some extent to other diseases so we will design a table and a test for differential diagnosis with such diseases because there is not a specific diagnostic test also taking into consideration to include in our current project A new promising medication (Radicava)which was first approved by FDA in 2015 in Japan 20 years after all old mentioned medications in this study and we started communication with a brilliant neurological doctor to plan using it first time ever in our country. Beside that we will recommend some important diet to follow for patients and some advises to avoid some risk factors which can develop this disease."
New Vision of Metformin in treating cancer
The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.
Neuroendocrine cells and peptidergic innervation in human and rat prostrate
Introduction The prostate causes a signi?cant number of medical problems in the adult male, and the lower urinary tract symptoms are accepted as an unavoidable consequence of male aging. Most of these symptoms are mainly due to clinical benign prostatic hyperplasia (BPH), which is the most frequent benign tumor in the male, in- pendent of race or culture. On the other hand, cancer of the prostate shows an increasing incidence, being the second leading cause of death in men, after lung cancer.
Multi-Photon Quantum Interference
Multi-Photon Quantum Interference covers the phenomena of quantum interference through the multi-photon effects of photon correlation. The author’s focus is on the temporal correlation among photons and how it influences the interference effect.
Microbes and oral squamous cell carcinoma : A network spanning infection and inflammation
Helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention.
Metastasis of Prostate Cancer
Without metastasis, prostate cancer would be both tolerable and treatable. The high incidence of indolent and organ confined disease is testament to this sweeping generalisation. Equally, if molecular markers of metastatic spread can be identified, then the choice of treatment for many patients would be easier and more radical, even curative. However, should prevention and treatment of the primary tumors prove difficult or impossible.
Investigative Electrocardiography in Epidemiological Studies and Clinical Trials
It reviews the prevalence and incidence and emphasizes the prognostic implications of common ECG abnormalities in contrasting populations. It provides a comprehensive, penetrating and critical analysis of topics such as QT prolongation in clinical drug trials, left ventricular hypertrophy, myocardial ischemia/infarction and epidemiological consideration of relative risks associated with ECG abnormalities. As such it is an essential tool in epidemiological or clinical research using ECGs and in investigations of possible adverse responses of new pharmacological agents.
Infections à papillomavirus : État des connaissances, pratiques et prévention vaccinale = Human papillomavirus infections : Current knowledge, practices and vaccination prevention
The impact of papillomavirus (HPV) infection is considerable. More than one in two women has been exposed to HPV in her lifetime and around 10% will develop a chronic infection. Of these, 20% will develop cervical cancer in the absence or failure of screening. In France, high-risk HPV infection causes 80,000 precancerous lesions, 3,400 cervical cancers and the death of 1,000 women every year. Smear screening performed at a regular rate and according to quality standards has resulted in a significant decrease in incidence and mortality over the past 20 years. However, despite this considerable success, the so-called preventable disease has not been eradicated; testing is a complex process that only benefits part of the population while those who benefit endure its weaknesses. Optimization of screening and treatment is now made possible by the use of innovative techniques including the smear in liquid suspension, the HPV test, and soon viral genotyping and molecular markers guaranteeing maximum protection. Because cervical cancer is the result of chronic HPV infection, we already have the extraordinary chance to prevent it with a prophylactic vaccine. This progress will have a major impact on our practices as it happens in a poorly prepared medico-sociological environment. This resolutely practical and educational book provides an overview of knowledge and perspectives on HPV infection and its associated pathologies while deciphering the new challenges and practices in the vaccine era.
Homocysteine : Related Vitamins and Neuropsychiatric Disorders
There is an increasing interest in the connection between the homocysteine metabolism and neuropsychiatric disease with a steeply increasing number of publications. In particular, the association between homocysteine metabolism and cognitive decline/dementia attracts much interest. If simple, non-toxic homocysteine-lowering treatment with vitamins can reduce the incidence of, or delay the onset of dementia, it would have an enormous impact in societies with a rapidly increasing number of elderly at risk for dementia. This book summarises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects.
Grey information : Theory and practical applications
he book covers the latest advances in grey information and systems research, providing a state-of-the-art overview of this important field. Covering the theoretical foundation, fundamental methods and main topics in grey information and systems research, this book includes all the elementary concepts: basic principles, grey numbers and their operations, grey equations and matrices, operators of sequences and generations of grey sequences, grey incidence analysis, grey clusters and grey statistical evaluations, grey systems modeling, grey combined models, grey prediction, grey decisions, grey programming, grey input and output and grey controls, etc.
Glucoszmine and Chondroitin between reality and tllusion
Despite the development of cancer treatments and the introduction of new treatments other than traditional treatments, the death rate is still high around the world for each type of cancer. Although conventional treatments are still common, as a first method in treatment, advanced new treatments have opened new horizon and have shown good efficacy in inhibiting cancer, either by treating them alone or in combination with conventional treatments, such as chemotherapy and radiation therapy. We mention in this research the latest methods of cancer treatment, such as targeted therapies in the treatment of solid cancers and leukemia. and will also mention the annual incidence rates of lines around the world. In cooperation with the head of the hematology division at the Mouwasat Hospital, Dr. Amin Suleiman, we studied cases of CML and MM patients being treated with modern therapies.
Genetic Engineering of Mesenchymal Stem Cells
MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
Gastroesophageal reflux disease : Principles of disease, diagnosis, and treatment
Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing prevalence and incidence in the last two decades. This book presents clinically relevant information for gastroenterologists, internists, surgeons, residents and also nurses, who frequently care for GERD patients.
Forced migration and mental health : Rethinking the care of refugees and displaced persons
In the last half century, the steadily increasing incidence of armed conflict (both within and between nations) has created mounting numbers of asylum seekers, refugees, and displaced persons. The provision of appropriate mental health services for these individuals has become a major focus of concern, but considerable controversy remains as to what kind of care is necessary. The initial assumptions and models that informed the field have recently come under attack, and alternative approaches have arisen. Forced Migration and Mental Health: Rethinking the Care of Refugees and Displaced Persons provides an up-to-date view of the controversies and future directions for the mental health care of those displaced by war or other extreme conditions.
Food Safety and Ways to Prevent Life-Threatening Pollutants
The fears regarding food safety started long time ago, and till this very moment of ours, the international organizations and INGOs pay lots of hard work to minimize and achieve reduction in the effects and the suffering caused to people around the world by contaminated foods each year. This research talks about the main patterns of food contaminants, and they are chemical, physical, biological, and last but not least the contamination caused by radioactive substances. It is also important to talk about the methods of precaution and protection against the diseases and illnesses produced by contaminated foods, as well about the role of INGOs which are dedicated and specialized in law and regulations enactment for bounding the incidence of food contamination in the world, for raising the public awareness towards food safety, and to keep up with the latest updates of events. This research also contains vast Information about Covid-19 and its spreading process via contaminated food.
Fetal compromise in labor
Sixty years ago, the purpose of introducing electronic fetal heart rate monitoring (EFM) was to reduce the incidence of intrapartum stillbirth. However, by the early 1980s, with falling stillbirth rates, fetal blood sampling had been widely abandoned, as many considered that EFM was sufficient on its own. Unfortunately, while the sensitivity of EFM for the detection of potential fetal compromise is high, specificity is low, and there is a high false positive rate which has been associated with a rising cesarean section rate. The authors suggest that EFM is considered and analyzed as a classic screening test and not a diagnostic test. Furthermore, it requires contextualization with other risk factors to achieve improved performance. A new proposed metric, the Fetal Reserve Index, takes into account additional risk factors and has demonstrated significantly improved performance metrics. It is going through the phases of further development, evaluation, and wider clinical implementation.
Essential Infectious Disease Topics for Primary Care
This book provides an easy-to-use, practical, yet comprehensive resource for family practitioners to use in the daily struggle against infectious diseases. It discusses vaccines and preventive measures as well as information on how to reduce the incidence of antimicrobial-resistant organisms by judiciously prescribing antibiotics and informing patients about the appropriate use of these agents.
Developmental Biology of Neoplastic Growth
In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest.
Demographic and Family Transition in Southeast Asia
The book is structured into two parts. Part A includes three segments preceded by a briefing on Southeast Asia. The first segment focuses on marital and partnership status in the region, particularly marriage rates, age at marriage, incidence of singlehood, cohabitation, and divorce. The second segment focuses on fertility indicators such as fertility rates (total, age-specific, adolescent), age at childbearing, and childlessness. The third presents information on household structures in the region by examining household sizes, and incidence of one-person households, single-parent families, as well as extended and composite households. Part B presents indicators of children and youth’s well-being.
Coloproctology
Coloproctology presents the state-of-the-art in coloproctology. All chapters give a comprehensive overview of etiology, incidence, epidemiology, diagnostics, medical and surgical treatment, complications and individual special considerations.
