Page 1
Page 1
In Silico Immunology
"in silico Immunology" is a book for the future: it will summarize these emergent disciplines and, while focusing on cutting edge developments, will address the issue of synergy as it shows how these three are set to transform immunological science and the future of health care.
Immunoinformatics
Immunoinformatics is an emerging subdiscipline of bioinformatics. It utilizes mathematics, information science, computer engineering, genomics, proteomics and immunological methods to bridge immunology and informatics. Similar to bioionformatics which became a driving force in genome research, immunoinformatics enables data-driven research strategies and systems approaches that aim at understanding the networks regulating the immune system. Considering the breath of topic, Immunoinformatics was composed to provide a cross-section of research ranging from data integration, epitope predictions to systems level applications. In ten chapters experts in the field introduce and discuss research strategies for immunologists and bioinformaticians who wish to endeavour existing and new approaches to gain insight into the workings of the immune system.
Immunogenetics: Methods and Protocols
Explores techniques for working in the field of immunogenetics, i.e. fundamental and translational research into the adaptive immune receptor repertoire. Many chapters are dedicated to lab protocols, bioinformatics, and immunoinformatics analysis of high-resolution immunome analysis, exemplified by numerous applications. Additionally, the newest technological variations on these protocols are discussed, including non-amplicon, single-cell, and cell-free strategies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Artificial immune systems ; Vol. 3627 ; 4th International conference, ICARIS 2005, Banff, Alberta, Canada, August 14-17, 2005, Proceedings
Your immune system is unique. It is in many ways as complex as your brain, butit is not centred in one location, like the brain. It is not a single organ—it consistsof many different cell types, diverse methods of intercellular communication, andmany different organs. Its functionality is blurred throughout you—we can’textract the immune system, or point to where it begins and ends. The immunesystem is not separable from the system it protects. It has integral links to everyorgan of our bodies.This has radical implications for the field of Artificial Immune Systems (AIS),that we are only now beginning to comprehend. One of the first insights is thatmodelling the immune system, or developing any kind of immune algorithm, isdifficult. The immune system is one aspect of biology that we find difficult toapply simple reductionist explanations to. We can very successfully extract sub-processes of the whole and create immune algorithms based on those processes.
