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Nimesulide - Actions and Uses

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs.

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Irritable Bowel syndrome I.B.S

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder with a range of symptoms that significantly affect quality of life for patients. Is currently one of the most common disorders of the digestive system in the Western society? Almost 2 out of 10 people suffer from IBS, and it is associated with abdominal pain, bloating and altered stool consistency and imposes a heavy burden for the affected patients. The difficulty of differential diagnosis and its treatment may significantly delay initiation of optimal therapy. Hence, persons with IBS often self-treat symptoms with non-prescribed pharmacological regimens and/or complementary and alternative medicines (CAM) and by modifying diet and daily activities.

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Introduction to Focused Ion Beams : Instrumentation, Theory, Techniques and Practice

Introduction to Focused Ion Beams is geared towards techniques and applications. The first portion of this book introduces the basics of FIB instrumentation, milling, and deposition capabilities. The chapter dedicated to ion-solid interactions is presented so that the FIB user can understand which parameters will influence FIB milling behavior. The remainder of the book focuses on how to prepare and analyze samples using FIB and related tools, and presents specific applications and techniques of the uses of FIB milling, deposition, and dual platform techniques. This is the only text that discusses and presents the theory directly related to applications and the only one that discusses the vast applications and techniques used in FIBs and Dual platform instruments.

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Ibuprofen : Pharmacology, Therapeutics and Side Effects

Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.

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Handbook of neurochemistry and molecular neurobiology : Brain Energetics. Integration of Molecular and Cellular Processes

Focuses on aspects of energy metabolism that are unique to the brain. The goal of each chapter is to provide a fundamental overview of each area, to define the state-of-the-art in that area as it relates to brain, and, where appropriate, describe models that portray poorly understood and apparently contradictory data sets with the goal of helping focus attention to experimental resolution of controversial issues.

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Fire properties of polymer composite materials

This book is the first to deal comprehensively with the important topic of the fire behaviour of polymer composite materials. Composites are used in a diverse range of applications, including land and marine transport, aerospace, the chemical industry, and most branches of civil engineering infrastructure. It is our belief that fire behaviour is the single most important factor limiting the wider use of composites in many of these areas. Our aim in producing this volume is therefore to stimulate the work that is needed to overcome this fundamental problem. The first step in such a journey is, of course, to summarise what is presently known, which is what we have attempted here. The book covers all of the key issues on the behaviour of polymer composites in fire.

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Ethics and Business : An Introduction

Offers a clear and accessible framework for understanding the important and complex ethical issues facing business in the contemporary world. Kevin Gibson explains ethical concepts in plain language, showing how terms such as responsibility, autonomy, justice, equality, rights, and beneficence are central to the ways in which business is and should be conducted.

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Landslides in research, theory and practice ; Proceedings of the 8th International Symposium on Landslides held in Cardiff on 26–30 June 2000

Contains vital information from throughout the world on landslide and slope instability problems. Every four years the worlds leading scientists and engineers dealing with landslides, have the opportunity to meet up and engage in the exchange of ideas and experiences at a symposium run under the auspices of ISSMGE Technical Committee 11. These volumes, taken from the 8th symposium in the series, detail investigations into landslide causes, mechanisms and hazards, together with accounts of monitoring and mapping.

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Laboratory Guide to the Methods in Biochemical Genetics

This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.

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Cleft and Craniofacial Orthodontics

Provides orthodontists, plastic and oral and maxillofacial surgeons, speech and language therapists, pediatric dentists, and prosthodontists with the information they need to evaluate and treat these conditions. Highlighting the multidisciplinary team approach, the book aids clinicians in developing a complete plan for their patients.

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Apoptotic pathways as targets for novel therapies in cancer and other diseases

The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients.

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