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Open and Toroidal Electrophoresis : Ultra-High Separation Efficiencies in Capillaries, Microchips and Slabs

Written by one of the developers of Toroidal Capillary Electrophoresis (TCE), this book is the first to present this novel analytical technique, in detail, to the field of analytical chemistry. The exact expressions of separation efficiency, resolution, peak capacity, and many other performance indicators of the open and toroidal layouts are presented and compared.

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Ontology Learning and Population from Text: Algorithms, Evaluation and Applications

Ontology Learning and Population from Text: Algorithms, Evaluation and Applications presents approaches for ontology learning from text and will be relevant for researchers working on text mining, natural language processing, information retrieval, semantic web and ontologies. Containing introductory material and a quantity of related work on the one hand, but also detailed descriptions of algorithms, evaluation procedures etc. on the other, this book is suitable for novices, and experts in the field, as well as lecturers.

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Ontologies for Software Engineering and Software Technology

The editors structured the contributions into three parts: first, a detailed introduction into the use of ontologies in software engineering and software technology in general; second, the use of ontologies to conceptualize different process-related domains such as software maintenance, software measurement, or SWEBOK, initiated by IEEE; third, the use of ontologies as artifacts in several software processes, like, for example, in OMG’s MOF or MDA.

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One-Dimensional Nanostructures

One-dimensional (1D) nanostructures, including nanowires, nanotubes and quantum wires, have been regarded as the most promising building blocks for nanoscale electronic and optoelectronic devices. Worldwide efforts in both the theory and the experimental investigation of growth, characterization and applications of 1D nanostructures have resulted in a mature, multidisciplinary field. In this book, a wealth of state-of-the-art information offers the opportunity to uncover the underlying science from diverse perspectives. Leading researchers elucidate the synthesis and properties of 1D nanostructures for various morphologies and compositions (semiconductor, metal, carbon, etc.) as well as their considerable impact on spintronics, information storage, and the design of field-effect transistors.

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Ondansetron Patches

The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.

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Oncology : An Evidence-Based Approach

Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.

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Oncologic and Cardiologic PET/CT-Diagnosis : An Interdisciplinary Atlas and Manual

Since 1999/2000 simultaneous imaging of anatomical features and metabolic activities using fused PET and CT images has complemented and in many cases even replaced what was originally done as separate analysis. – Is this a small revolution? – In fact, this new approach can be considered to be without a rival for imaging diagnosis. The complementary efforts of nuclear medicine physicians and radiologists have improved the diagnostic value of PET/CT scans. The successful use of PET/CT in the field of oncology has been documented world-wide, and in cardiology we can take advantage of the significant findings of PET diagnosis, particularly in the USA. New prospects are now available for paediatric oncology and molecular medicine.

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Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).

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On the path to AI : Law’s prophecies and the conceptual foundations of the machine learning age

This book explores machine learning and its impact on how we make sense of the world. It does so by bringing together two ‘revolutions’ in a surprising analogy: the revolution of machine learning, which has placed computing on the path to artificial intelligence, and the revolution in thinking about the law that was spurred by Oliver Wendell Holmes Jr in the last two decades of the 19th century.

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On The Interpretation of Treaties : The Modern International Law as Expressed in the 1969 Vienna Convention on the Law of Treaties

This book investigates the contents and structure of this system. By importing knowledge from linguistics, and pragmatics in particular, a model is established giving representation to the concept of a rule of interpretation. Drawing on this model, the book then proceeds to reconstruct the contents of the various rules of interpretation. To facilitate reference, the conclusions suggest a list of 44 rules, all of which can be invoked by appliers citing VCLT Articles 31-33.

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Omics sudies of medicinal plants

Herbal drugs play a pivotal role in modern medicine and pharmaceutical care; however, only limited biotechnology applications have been seen in medicinal plants. Revolutions in high-throughput approaches emphasize omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. A volume in the Exploring Medicinal Plants series, this book provides a comprehensive and in-depth analysis of breakthroughs in high-throughput approaches for the research of medicinal plants.

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Omega 3 and Omega 6 and its relationship to obesity

This research summarizes information about omega-3 and omega-6. In recent times, there has been growing recognition of the key role of foods and beverages in disease prevention and treatment. Thus, the production and consumption of functional foods has gained much importance as they provide a health benefit beyond the basic nutritional functions. At present, PUFA (poly unsaturated fatty acids) as Omega-3 [(n-3)] fatty acids and Omega -6 [(n-6)] fatty acid have been linked to healthy aging throughout life. Recently, omega-3 fatty acids EPA (eicosapentaenoic acid ) and DHA (docosahexaenoic acid ) have been associated with cardiovascular function, and Alzheimer’s disease.

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Oilseeds

Genome Mapping and Molecular Breeding in Plants presents the current status of the elucidation and improvement of plant genomes of economic interest. The focus is on genetic and physical mapping, positioning, cloning, monitoring of desirable genes by molecular breeding and the most recent advances in genomics. The series comprises seven volumes: Cereals and Millets; Oilseeds; Pulses, Sugar and Tuber Crops; Fruits and Nuts; Vegetables; Technical Crops; and Forest Trees.

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Ocean Waves Breaking and Marine Aerosol Fluxes

This book presents a comprehensive study on the breaking of surface waves induced by wind and the relationship of breaking rate with marine aerosol fluxes. The book draws attention to the theoretical and experimental achievements in the study of wave breaking phenomena in deep water seas. In particular, it deals with the important problems of energy dissipation and the estimation of energy loss due to wave breaking in deep waters. The rationale behind existing methods and practical outcomes for the estimation of whitecap coverage of the sea surface and energy dissipation rate are given in detail.The book also focuses on the fundamentals of marine aerosols and their generation. The text provides a comprehensive overview of the currently available experimental data on marine aerosol fluxes and presents theoretical methodology of the estimation of the intensity of sea aerosol production. The systematic analysis leads to a novel approach in the development of links between aerosol production with sea state parameters and its seasonal variation in deep water seas.

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Occlusal splints for painful craniomandibular dysfunction

Bridges that gap, presenting a practical guide for the treatment of craniomandibular dysfunction (CMD)—a functional disorder that affects the muscles of mastication, temporomandibular joints, and/or occlusion—in patients with related pain. The first half of the book provides detailed but simple clinical instructions and examples of occlusal splint therapy, including splint fabrication and coordinative training for painful CMD, based entirely on a high level of evidence. The second half delves deeper into the etiology, advanced diagnostic techniques, neurobiology, and pathophysiology of painful CMD and splint therapy.

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Obstetric medicine : A problem-based approach

This book is a collection of exam questions and case studies which illustrates both common and more unusual problems in obstetric medicine. Using a problem–based approach to both teach and test knowledge, it incorporates many different approaches to obstetric medicine, in Q & A format. The ‘Extended Matched Questions’ section covers the breadth of theoretical knowledge. The ‘Short Answers / Data Interpretation’ section requires a systematic approach to a clinical problem. Most of the case reports are based on real cases and all are accompanied by a brief literature review to further broaden the learning experience.

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Observing the Sun with Coronado™ Telescopes

At around the turn of the millennium, the introduction of the Coronado range of solar telescopes and filters heralded the ‘coming of age’ of amateur solar astronomy. Before then, solar astronomy was mostly white-light only. Hydrogen-alpha systems were expensive and difficult to use, but today even the budget-priced Coronado PST (Personal Solar Telescope) provides a band pass of one Angstrom and is thermally stable. That means that today’s amateur solar observers can see – and image – sunspots, flares, prominences, plage, filaments, and active regions of the Sun, all in amazing detail.

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Object-Oriented Programming Languages : Interpretation

This comprehensive examination of the main approaches to object-oriented language explains the key features of the languages in use today. Class-based, prototypes and Actor languages are all looked at and compared in terms of their semantic concepts. In providing such a wide-ranging comparison, this book provides a unique overview of the main approaches to object-oriented languages.

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Objective information theory

Objective Information Theory (OIT) is proposed to represent and compute the information in a large-scale complex information system with big data in this monograph. To formally analyze, design, develop, and evaluate the information, OIT interprets the information from essential nature, measures the information from mathematical properties, and models the information from concept, logic, and physic. As the exemplified applications, Air Traffic Control System (ATCS) and Smart Court SoSs (System of Systems) are introduced for practical OITs.

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Object-Based Image Analysis and Treaty Verification : New Approaches in Remote Sensing – Applied to Nuclear Facilities in Iran

This book describes recent progress in object-based image interpretation, and also presents many new results in its application to verification of nuclear non-proliferation. ​A comprehensive workflow and newly developed algorithms for object-based high resolution image (pre-) processing, feature extraction, change detection, classification and interpretation are developed, applied and evaluated. The entire analysis chain is demonstrated with high resolution imagery acquired over Iranian nuclear facilities.

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