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Model-Driven Software Development
Abstraction is the most basic principle of software engineering. Abstractions are provided by models. Modeling and model transformation constitute the core of model-driven development. Models can be refined and finally be transformed into a technical implementation, i.e., a software system. The aim of this book is to give an overview of the state of the art in model-driven software development. Achievements are considered from a conceptual point of view in the first part, while the second part describes technical advances and infrastructures. Finally, the third part summarizes experiences gained in actual projects employing model-driven development. Beydeda, Book and Gruhn put together the results from leading researchers in this area, both from industry and academia. The result is a collection of papers which gives both researchers and graduate students a comprehensive overview of current research issues and industrial forefront practice, as promoted by OMG’s MDA initiative.
Evolutionary Genomics : Statistical and Computational Methods
This book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results.
