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Neurodegeneration in Multiple Sclerosis
In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic reliability and to monitor the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy as to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is dramatically changing our understanding of how MS causes irreversible disability.
Mute people aiding application
Communication is an essential tool for human survival. It is a fundamental and effective method of sharing thoughts, needs, feelings, and opinions. However, a large portion of the world's population lacks the ability to communicate with others. Such as the ones suffering from hearing loss, speech disability, or even both. Those disabilities have a significant impact on their lives in terms of work and relationships. The majority of these people are sometimes unable to support themselves financially due to the lack of job opportunities. Given these difficulties, we have decided to develop an application to help them overcome the obstacles they may encounter in their daily lives. After consulting with two deaf and mute people we customized an application that works in two ways. One of which is to translate their sign language in real time by using mobile camera and recognizing hand motion. The other works by converting text-to-voice, and accurately expressing the user’s emotions with the help of the facial emotion recognition.
Multiple Sclerosis: Autoimmunity and Management
Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20–25 years in more than 30% of patients. The hallmark of MS is symptomatic episodes that occur months or years apart and affect different anatomic locations. Also, see the Autoimmune Disorders: Making Sense of Nonspecific Symptoms slideshow to help identify several diseases that can cause a variety of nonspecific symptoms. MS is diagnosed on the basis of clinical findings and supporting evidence from ancillary tests. Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as nonpharmacologic treatments, such as physical and occupational therapy. Disease-modifying therapies have shown beneficial effects in patients with relapsing MS, including reduced frequency and severity of clinical attacks. These agents appear to slow the progression of disability and the reduce accumulation of lesions within the brain and spinal cord.
International criminal law : Using or abusing legality
Analyses the relationship between law and violence, the utility of law over violence and whether legality as an approach has an inherent disability in addressing mass violence as a crime. The study is located within international law and assesses whether prosecuting political violence would necessarily entail an abuse of the legal process. The intention is to encourage definition of criminal aggression via legal processes laid down by the International Criminal Court,
International Actors and the Formation of Laws
This book addresses the discourse that creates, modifies, and reshapes the law, as well as discourse participants. The book focuses on the actors operating in legal regimes and their subtly, bluntly, or even outright aggressive impact on the formation of laws. As the book examines the intersection of domestic, European, international, and even transnational, legal regimes where new law emerges as a product of this discourse, it contributes to the understanding of the mobility of law and contemporary law’s interactive nature. This book provides enlightening examples of diverse legal fields influenced by international, non-domestic actors. It covers a wide range of relevant topics, from financial sanctions to the rights of indigenous peoples, and addresses actors ranging from the European Union and the European Court of Human Rights to disability organizations. By exploring actors, the book stresses their objectives and driving forces behind their efforts to influence law. The book reveals an array of diverging methods used by international actors to influence law. Additionally, the book resonates with Nordic legal tradition and highlights Nordic commitment to rule of law and equality.
Impossible Bodies, Impossible Selves : Exclusions and Student Subjectivities
This book looks inside the school to examine how every-day, school-level processes act to place particular students 'outside' the educational endeavour and argues for new strategies for thinking critically about and interrupting educational exclusions and inequalities.The book uses tools offered by post-structural theory to read ethnographic data and show how the discourses that circulate inside schools at once mobilize and elide gender, sexuality, social class, ability, disability, race, ethnicity, religious and cultural belongings at the same time as they open up and close down 'who' students can be as learners.
Healthy Longevity in China : Demographic, Socioeconomic, and Psychological Dimensions
China is aging at an extraordinary speed and has the largest quantity of elderly persons in the world. Scholars utilize this unprecedented living experience of human being and the unique Chinese Longitudinal Healthy Longevity Survey (CLHLS) datasets with the aim to answer in this volume the following questions critical to the aging population world wide. Is the period of disability compressing or expanding with increasing life expectancy and what factors are associated with these trends in the recent decades? Is it possible to realize morbidity compression with a prolongation of the life span in the future?The first section of the book presents the CLHLS project’s study design, sample distribution, contents of data collected, and assessments of age reporting and data quality. The remaining chapters are grouped into sections dealing with the demographic, social, economic, familial and psychological dimensions of healthy longevity.
Handbook of Complex Occupational Disability Claims : Early Risk Identification, Intervention, and Prevention
A book that synthesizes so many diverse viewpoints has the potential to influence both policy and practice across disciplines and cut through politicization of these still poorly understood conditions with evidence. The Handbook is important reading for all clinicians, professionals, and members of rehabilitation and disability management teams, across healthcare, occupational and compensation settings.
Genetic surgery : from genes to solutions
As a tool for modifying the genome, gene editing technologies has developed rapidly in recent years, the application of these technologies in basic biomedical research has yielded significant advances in identifying and studying key molecular targets relevant to human diseases and their treatment. The clinical translation of genome editing techniques offers unprecedented biomedical engineering capabilities in the diagnosis, prevention, and treatment of disease or disability...
Fire-fighter robot
Firefighting is an important but dangerous career that can potentially cause the loss of life, property damage and permanent disability to the victim. Robots are designed to find a fire, before it rages out of control, could one day work with fire fighters greatly reducing the risk of injury to victims. In this report we will focus on each phase of the project one by one and demonstrate them.
Fecal Incontinence : Diagnosis and Treatment
Fecal incontinence is a frequent, distressing condition that has a devastating impact on patients’ lives. However, patients are typically embarrassed and reluctant to acknowledge this disability, so they relinquish the possibility of being cured and remain socially isolated. Since fecal incontinence may result from various pathophysiological situations, an accurate diagnostic work-up of each patient is fundamental. Today, a wide range of therapeutic options is available, but making the correct choice is pivotal to the successful management of this condition. This book is aimed at all physicians involved in the assessment and treatment of fecal incontinence. Its main purpose is to review the latest advances in the epidemiologic, socio-economic, psychologic, diagnostic, and therapeutic aspects of fecal incontinence, in order to establish guidelines for effective treatment.
Explainable artificial intelligence in troke from the clinical, rehabilitation and nursing perspectives
As we know, strokes are one of the world's leading causes of death, and the cruel aspect of a stroke is that it leaves people with severe functional disability and/or cognitive impairment. Strokes have a significant impact on economies worldwide, as it is estimated that about 10% of the male population and 8% of the female population are affected by them. Such people need personal help in their everyday life and must be materially supported by social services. With the advancement of medicine, artificial intelligence, and new technologies have been developing rapidly and are gradually applied in diseases of the nervous system, increasingly helping diagnosis, treatment, rehabilitation, and prognosis of disease.
Education for Children with Disabilities in Addis Ababa, Ethiopia : Developing a Sense of Belonging
This book presents insights into the lived realities of children with disabilities in primary schools in Addis Ababa, Ethiopia. It examines specific cultural and societal characteristics of Ethiopia that influence the education of children with disabilities. The book presents findings drawn from interviews with, and participant observation of the schoolchildren, family members, teachers and other “experts”, and places these findings in a cultural-historical context. The multidimensional approach taken allows for, on the one hand, the provision of a historical grounding of the book, explaining the main historical junctures and their implications for education, and the discussion of the role of culture and society as barriers and facilitators of education.
Disability, Health and Human Development
Introduces the human development model to define disability and map its links with health and wellbeing, based on Sen’s capability approach. The author uses panel survey data with internationally comparable questions on disability for Ethiopia, Malawi, Tanzania and Uganda. It presents evidence on the prevalence of disability and its strong and consistent association with multidimensional poverty, mortality, economic insecurity and deprivations in education, morbidity and employment. It shows that disability needs to be considered from multiple angles including aging, gender, health and poverty. Ultimately, this study makes a call for inclusion and prevention interventions as solutions to the deprivations associated with impairments and health conditions.
Disability in Islamic Law
The book analyzes attitudes to people with various disabilities based on Muslim jurists’ works (fiqh) in the Middle Ages and the modern era. In the Islamic legal literature people with disabilities are mentioned sporadically, and often within broad topics such as religious duties, jihad, marriage, etc., but seldom as a subject by its own right. Very little has been written so far on people with disabilities in a general Islamic context, much less in reference to Islamic law. This is the innovation of the book.
Dental Care for Children with Special Needs : A Clinical Guide
This concise manual offers best practice guidance on dental treatment of pediatric patients with special health care needs (CSHCN). Readers will find up-to-date information on case-based treatment planning, alternative caries management strategies, the use of behavioral and pharmacological interventions to facilitate delivery of quality treatment, and a team approach to care.
Coping with Chronic Illness and Disability : Theoretical, Empirical, and Clinical Aspects
Individuals’ responses to their chronic illness or disability (CID) vary widely. Some are positive and productive, some negative and self-defeating, and some have elements of both. Coping with Chronic Illness and Disability synthesizes the growing literature on these coping styles and strategies by analyzing how individuals with CID face challenges, find and use their strengths, and alter their environment to fit their life-changing realities. The book’s first section provides readers with the major theories and conceptual perspectives on coping, with special emphasis on social aspects and models of coping with different types of CID. In Part Two, an array of specific medical conditions is covered. Each chapter supplies a clinical description, current empirical findings on coping, effective medical, physical, and psychological interventions, employment issues, and social concerns.
Cognitive Behavioral Therapy for Chronic Illness and Disability
Severe pain, debilitating fatigue, sleep disruption, severe gastrointestinal distress – these hallmarks of chronic illness complicate treatment as surely as they disrupt patients’ lives, in no small part because of the overlap between biological pathology and resulting psychological distress. Cognitive Behavioral Therapy for Chronic Illness and Disability cuts across formal diagnostic categories to apply proven therapeutic techniques to potentially devastating conditions, from first assessment to end of treatment. Four extended clinical case examples of patients with chronic fatigue, rheumatoid arthritis, inoperable cancer, and Crohn’s disease are used throughout the book to demonstrate how cognitive-behavioral interventions can be used to effectively address ongoing medical stressors and their attendant depression, anxiety, and quality-of-life concerns. At the same time, they highlight specific patient and therapist challenges commonly associated with chronic conditions.
Clinical Pathways in Stroke Rehabilitation : Evidence-based Clinical Practice Recommendations
This book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation.
Longer Life and Healthy Aging
Focuses on theoretical issues and empirical findings related to trends and determinants of healthy aging, including factors related to "healthy longevity" of the oldest-old, aged 80 and over. The group is the most rapidly increasing elderly sub-population and is most likely to need assistance in daily living in all countries. Chapters include both longitudinal and cross-sectional data from North America, Europe, and Asia in country-specific studies and cross-national comparisons. Part I focuses on the definition, components, concepts, measurements, and determinants of healthy aging, and discusses the trends and patterns of disability and healthy life expectancy at the macro level. Part II addresses individual healthy aging, including its biological and socio-demographic aspects. Part III focuses on issues concerning the family and healthy aging, and Part IV explores formal and informal care for healthy aging through governmental policy interventions and community service programs.
